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Year Number of Results
1988 1
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340 results

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Page 1
Mechanism and regulation of kinesin motors.
Yildiz A. Yildiz A. Nat Rev Mol Cell Biol. 2025 Feb;26(2):86-103. doi: 10.1038/s41580-024-00780-6. Epub 2024 Oct 11. Nat Rev Mol Cell Biol. 2025. PMID: 39394463 Review.
Kinesins are a diverse superfamily of microtubule-based motors that perform fundamental roles in intracellular transport, cytoskeletal dynamics and cell division. These motors share a characteristic motor domain that powers unidirectional motility and force generati …
Kinesins are a diverse superfamily of microtubule-based motors that perform fundamental roles in intracellular transport, cyto …
The cytoplasmic dynein transport machinery and its many cargoes.
Reck-Peterson SL, Redwine WB, Vale RD, Carter AP. Reck-Peterson SL, et al. Nat Rev Mol Cell Biol. 2018 Jun;19(6):382-398. doi: 10.1038/s41580-018-0004-3. Nat Rev Mol Cell Biol. 2018. PMID: 29662141 Free PMC article. Review.
Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells. Dynein has critical roles both in interphase and during cell division. ...A central challenge in the field is to understand how a single motor can transport such a diverse array o …
Cytoplasmic dynein 1 is an important microtubule-based motor in many eukaryotic cells. Dynein has critical roles both in inter …
Actin-based regulation of ciliogenesis - The long and the short of it.
Copeland J. Copeland J. Semin Cell Dev Biol. 2020 Jun;102:132-138. doi: 10.1016/j.semcdb.2019.12.005. Epub 2019 Dec 18. Semin Cell Dev Biol. 2020. PMID: 31862221 Review.
The primary cilia is found on the mammalian cell surface where it serves as an antenna for the reception and transmission of a variety of cellular signaling pathways. At its core the cilium is a microtubule-based organelle, but it is clear that its assembly and func …
The primary cilia is found on the mammalian cell surface where it serves as an antenna for the reception and transmission of a variety of ce …
Microtubules and spermatogenesis.
O'Donnell L, O'Bryan MK. O'Donnell L, et al. Semin Cell Dev Biol. 2014 Jun;30:45-54. doi: 10.1016/j.semcdb.2014.01.003. Epub 2014 Jan 17. Semin Cell Dev Biol. 2014. PMID: 24440897 Review.
Microtubules are dynamic polymers of tubulin subunits that underpin many essential cellular processes, such as cell division and migration. Spermatogenesis is the process by which spermatogenic stem cells undergo mitotic and meiotic division and differentiation to p …
Microtubules are dynamic polymers of tubulin subunits that underpin many essential cellular processes, such as cell division and migr …
Centriole length control.
Sharma A, Olieric N, Steinmetz MO. Sharma A, et al. Curr Opin Struct Biol. 2021 Feb;66:89-95. doi: 10.1016/j.sbi.2020.10.011. Epub 2020 Nov 18. Curr Opin Struct Biol. 2021. PMID: 33220554 Free article. Review.
Centrioles are microtubule-based structures involved in cell division and ciliogenesis. Centriole formation is a highly regulated cellular process and aberrations in centriole structure, size or numbers have implications in multiple human pathologies. …
Centrioles are microtubule-based structures involved in cell division and ciliogenesis. Centriole formation is a highly reg
Removal of cellular protrusions.
Inaba M, Ridwan SM, Antel M. Inaba M, et al. Semin Cell Dev Biol. 2022 Sep;129:126-134. doi: 10.1016/j.semcdb.2022.02.025. Epub 2022 Mar 5. Semin Cell Dev Biol. 2022. PMID: 35260295 Free PMC article. Review.
However, the typical approaches for understanding signaling regulation tend to focus solely on changes in signaling molecules, such as gene expression, protein-protein interaction, and degradation. In this short review, we summarize the studies proposing the removal of dif …
However, the typical approaches for understanding signaling regulation tend to focus solely on changes in signaling molecules, such a …
Protein Lactylation and Metabolic Regulation of the Zoonotic Parasite Toxoplasma gondii.
Yin D, Jiang N, Cheng C, Sang X, Feng Y, Chen R, Chen Q. Yin D, et al. Genomics Proteomics Bioinformatics. 2023 Dec;21(6):1163-1181. doi: 10.1016/j.gpb.2022.09.010. Epub 2022 Oct 7. Genomics Proteomics Bioinformatics. 2023. PMID: 36216028 Free PMC article.
Lactylated proteins were distributed in multiple subcellular compartments and were closely related to a wide variety of biological processes, including mRNA splicing, glycolysis, aminoacyl-tRNA biosynthesis, RNA transport, and many signaling pathways. We also performed a c …
Lactylated proteins were distributed in multiple subcellular compartments and were closely related to a wide variety of biological proces
Ciliogenesis membrane dynamics and organization.
Zhao H, Khan Z, Westlake CJ. Zhao H, et al. Semin Cell Dev Biol. 2023 Jan 15;133:20-31. doi: 10.1016/j.semcdb.2022.03.021. Epub 2022 Mar 26. Semin Cell Dev Biol. 2023. PMID: 35351373 Free PMC article. Review.
Ciliogenesis is a complex multistep process used to describe assembly of cilia and flagella. These organelles play essential roles in motility and signaling on the surface of cells. ...As is the case in the biogenesis of other cellular organelles, regulators of memb …
Ciliogenesis is a complex multistep process used to describe assembly of cilia and flagella. These organelles play essential roles in …
Association of microtubule-based processes gene expression with immune microenvironment and its predictive value for drug response in oestrogen receptor-positive breast cancer.
Huang Z, Zhang M, Zhang N, Zeng M, Qian Y, Zhu M, Meng X, Shan M, Zhang G, Liu F. Huang Z, et al. Front Immunol. 2025 Jul 30;16:1608991. doi: 10.3389/fimmu.2025.1608991. eCollection 2025. Front Immunol. 2025. PMID: 40808956 Free PMC article.
OBJECTIVE: The development of acquired endocrine resistance and reduced chemosensitivity in oestrogen receptor-positive (ER+) breast cancer presents significant challenges. Microtubule-based process-related genes (MBPRGs) play essential biological roles in th …
OBJECTIVE: The development of acquired endocrine resistance and reduced chemosensitivity in oestrogen receptor-positive (ER+) breast cancer …
Liquid-Liquid Phase Separation-Mediated Cellular-Scale Compartmentalization of Hydrogel Covalent Cross-Linking Promotes Microtubule-Based Mechanosensing.
Zhao J, Hu Y, Li H, Liu C, Nie Z, Chen Z, Ling Q, Li Z, Zhao P, Song B, Zhang K, Bian L. Zhao J, et al. J Am Chem Soc. 2025 Apr 30;147(17):14336-14347. doi: 10.1021/jacs.5c00079. Epub 2025 Apr 19. J Am Chem Soc. 2025. PMID: 40252026
The obtained ECM-mimetic heterogeneous hydrogel, which is solely cross-linked by covalent bonds, promotes extensive spreading, microtubule-based mechanotransduction, and autophagic flux of encapsulated human mesenchymal stem cells (hMSCs), thereby enhancing osteogen …
The obtained ECM-mimetic heterogeneous hydrogel, which is solely cross-linked by covalent bonds, promotes extensive spreading, microtubul
340 results