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Regulation of lung immunity and host defense by the intestinal microbiota.
Samuelson DR, Welsh DA, Shellito JE. Samuelson DR, et al. Front Microbiol. 2015 Oct 7;6:1085. doi: 10.3389/fmicb.2015.01085. eCollection 2015. Front Microbiol. 2015. PMID: 26500629 Free PMC article. Review.
Therefore, understanding the mechanistic basis for host defense against infection and regulation of immune processes involved in asthma are crucial for the development of novel therapeutic strategies. ...This review explores the current research descri …
Therefore, understanding the mechanistic basis for host defense against infection and regulation of immune proce …
Probiotics in Medicine: A Long Debate.
Stavropoulou E, Bezirtzoglou E. Stavropoulou E, et al. Front Immunol. 2020 Sep 25;11:2192. doi: 10.3389/fimmu.2020.02192. eCollection 2020. Front Immunol. 2020. PMID: 33072084 Free PMC article. Review.
It is accepted that there is a mutual communication between the gut microbiota and the liver, the so-called "microbiota-gut-liver axis" as well as a reciprocal communication between the intestinal microbiota and the central nervous system through the " …
It is accepted that there is a mutual communication between the gut microbiota and the liver, the so-called "microbiota-gut-li …
The regulation of host defences to infection by the microbiota.
Brown RL, Clarke TB. Brown RL, et al. Immunology. 2017 Jan;150(1):1-6. doi: 10.1111/imm.12634. Epub 2016 Aug 9. Immunology. 2017. PMID: 27311879 Free PMC article. Review.
The regulation of immunity by the microbiota helps to protect the host against intestinal and extra-intestinal infection by many classes of pathogen. In this review, we will discuss the experimental evidence supporting a role for the m
The regulation of immunity by the microbiota helps to protect the host against intestinal and extra-in
Effect of gut microbiota on LPS-induced acute lung injury by regulating the TLR4/NF-kB signaling pathway.
Tang J, Xu L, Zeng Y, Gong F. Tang J, et al. Int Immunopharmacol. 2021 Feb;91:107272. doi: 10.1016/j.intimp.2020.107272. Epub 2020 Dec 22. Int Immunopharmacol. 2021. PMID: 33360370
Intestinal microflora disorder affect lung diseases through the gut-lung axis. ...Accordingly, gut microbiota imbalance may regulate the TLR4/NF-kB signaling pathway in the lung immune system, activating oxidative stress in the
Intestinal microflora disorder affect lung diseases through the gut-lung axis. ...Accordingly, gut microbiota im
The microbiota protects against respiratory infection via GM-CSF signaling.
Brown RL, Sequeira RP, Clarke TB. Brown RL, et al. Nat Commun. 2017 Nov 15;8(1):1512. doi: 10.1038/s41467-017-01803-x. Nat Commun. 2017. PMID: 29142211 Free PMC article.
We show that the microbiota enhances respiratory defenses via granulocyte-macrophage colony-stimulating factor (GM-CSF) signaling, which stimulates pathogen killing and clearance by alveolar macrophages through extracellular signal-regulated kinase signaling. …
We show that the microbiota enhances respiratory defenses via granulocyte-macrophage colony-stimulating factor (GM-CSF) signal …
The Potential Use of Grape Phytochemicals for Preventing the Development of Intestine-Related and Subsequent Inflammatory Diseases.
Santa K, Kumazawa Y, Nagaoka I. Santa K, et al. Endocr Metab Immune Disord Drug Targets. 2019;19(6):794-802. doi: 10.2174/1871530319666190529105226. Endocr Metab Immune Disord Drug Targets. 2019. PMID: 31142251 Review.
DISCUSSION: Grape phytochemicals mainly consist of a variety of chemicals that include terpenoid (oleanolic acid), carotenoids (beta-carotene, lutein), and flavonoids: flavon-3-ols (quercetin), flavan-3-ols (catechins), anthocyanins, oligomers and polymers (tannins and proanthocy …
DISCUSSION: Grape phytochemicals mainly consist of a variety of chemicals that include terpenoid (oleanolic acid), carotenoids (beta-caroten …
Mast cells participate in regulation of lung-gut axis during Staphylococcus aureus pneumonia.
Liu C, Yang L, Han Y, Ouyang W, Yin W, Xu F. Liu C, et al. Cell Prolif. 2019 Mar;52(2):e12565. doi: 10.1111/cpr.12565. Epub 2019 Feb 7. Cell Prolif. 2019. PMID: 30729611 Free PMC article.
RESULTS: After S. aureus challenge, the MC-deficient mice, compared with wild-type (WT) mice, displayed attenuated lung inflammation, decreased expression of CRAMP, higher bacterial lung load and disturbance of the intestinal microbiota. Adoptiv …
RESULTS: After S. aureus challenge, the MC-deficient mice, compared with wild-type (WT) mice, displayed attenuated lung inflam …
Early innate immunity to bacterial infection in the lung is regulated systemically by the commensal microbiota via nod-like receptor ligands.
Clarke TB. Clarke TB. Infect Immun. 2014 Nov;82(11):4596-606. doi: 10.1128/IAI.02212-14. Epub 2014 Aug 18. Infect Immun. 2014. PMID: 25135683 Free PMC article.
The commensal microbiota is a major regulator of the immune system. The majority of commensal bacteria inhabit the gastrointestinal tract and are known to regulate local mucosal defenses against intestinal pathogens. ...Importantly …
The commensal microbiota is a major regulator of the immune system. The majority of commensal bacteria inhabit the g
Intestinal Microbiota of Mice Influences Resistance to Staphylococcus aureus Pneumonia.
Gauguet S, D'Ortona S, Ahnger-Pier K, Duan B, Surana NK, Lu R, Cywes-Bentley C, Gadjeva M, Shan Q, Priebe GP, Pier GB. Gauguet S, et al. Infect Immun. 2015 Oct;83(10):4003-14. doi: 10.1128/IAI.00037-15. Epub 2015 Jul 27. Infect Immun. 2015. PMID: 26216419 Free PMC article.
Th17 immunity in the gastrointestinal tract is regulated by the intestinal microbiota composition, particularly the presence of segmented filamentous bacteria (sfb), but the role of the intestinal microbiota in pulmonary host
Th17 immunity in the gastrointestinal tract is regulated by the intestinal microbiota composition, partic …
Gut microbiota modulates type I interferon and antibody-mediated immune responses in chickens infected with influenza virus subtype H9N2.
Yitbarek A, Alkie T, Taha-Abdelaziz K, Astill J, Rodriguez-Lecompte JC, Parkinson J, Nagy É, Sharif S. Yitbarek A, et al. Benef Microbes. 2018 Apr 25;9(3):417-427. doi: 10.3920/BM2017.0088. Epub 2018 Jan 30. Benef Microbes. 2018. PMID: 29380643
Commensal gut microbes play a critical role in shaping host defences against pathogens, including influenza viruses. The current study was conducted to assess the role and mechanisms of action of commensal gut microbiota on the innate and antibody-mediated re …
Commensal gut microbes play a critical role in shaping host defences against pathogens, including influenza viruses. The curre …