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Acute kidney injury in COVID-19 patients receiving remdesivir: A systematic review and meta-analysis of randomized clinical trials.
Shams G, Kazemi A, Jafaryan K, Morowvat MH, Peymani P, Karimzadeh I. Shams G, et al. Clinics (Sao Paulo). 2023 Apr 13;78:100200. doi: 10.1016/j.clinsp.2023.100200. eCollection 2023. Clinics (Sao Paulo). 2023. PMID: 37120984 Free PMC article.
OBJECTIVES: Remdesivir is an antiviral agent with positive effects on the prognosis of Coronavirus Disease (COVID-19). However, there are concerns about the detrimental effects of remdesivir on kidney function which might consequently lead to Acute Kidney …
OBJECTIVES: Remdesivir is an antiviral agent with positive effects on the prognosis of Coronavirus Disease (COVID-19). However, there …
Remdesivir Alleviates Acute Kidney Injury by Inhibiting the Activation of NLRP3 Inflammasome.
Yin L, Zhao H, Zhang H, Li Y, Dong Y, Ju H, Kong F, Zhao S. Yin L, et al. Front Immunol. 2021 May 21;12:652446. doi: 10.3389/fimmu.2021.652446. eCollection 2021. Front Immunol. 2021. PMID: 34093539 Free PMC article.
Acute kidney injury (AKI) is a frequent clinical complication in critically ill patients, and it rapidly develops into renal failure with high morbidity and mortality. However, other than dialysis, no effective therapeutic interventions can offer reliable treatment …
Acute kidney injury (AKI) is a frequent clinical complication in critically ill patients, and it rapidly develops into renal f …
Acute Kidney Injury Associated With Remdesivir: A Comprehensive Pharmacovigilance Analysis of COVID-19 Reports in FAERS.
Wu B, Luo M, Wu F, He Z, Li Y, Xu T. Wu B, et al. Front Pharmacol. 2022 Mar 25;13:692828. doi: 10.3389/fphar.2022.692828. eCollection 2022. Front Pharmacol. 2022. PMID: 35401177 Free PMC article.
Acute kidney injury (AKI) is a common complication among patients with the novel coronavirus (COVID-19). ...The mean time to AKI event onset was 4.91 7.25 days in COVID-19 cases with remdesivir therapy. The fatality proportion was 36.45% in AKI cases with …
Acute kidney injury (AKI) is a common complication among patients with the novel coronavirus (COVID-19). ...The mean time to A …
Remdesivir for COVID-19 and acute kidney injury: disproportionality analysis of data from the U.S. Food and Drug Administration Adverse Event Reporting System.
Li X, Zhou L, Gaggl M, Kinlaw AC, Gou Z, Xu Y, Wei J, Wang T. Li X, et al. Int J Clin Pharm. 2023 Apr;45(2):509-514. doi: 10.1007/s11096-023-01554-4. Epub 2023 Mar 24. Int J Clin Pharm. 2023. PMID: 36964312 Free PMC article.
BACKGROUND: Evidence about remdesivir-associated acute kidney injury (AKI) among patients with novel coronavirus disease 2019 (COVID-19) was controversial. ...Number of signals in sensitivity analyses and the proportion of AKI in remdesivir-associated …
BACKGROUND: Evidence about remdesivir-associated acute kidney injury (AKI) among patients with novel coronavirus diseas …
Remdesivir.
[No authors listed] [No authors listed] 2022 Feb 3. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2022 Feb 3. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 33211457 Free Books & Documents. Review.
Remdesivir is an antiviral nucleotide analogue used for therapy of severe novel coronavirus disease 2019 (COVID-19) caused by severe acute respiratory syndrome (SARS) coronavirus 2 (CoV-2) infection. Remdesivir therapy is given intravenously for 3 to 10 days and is …
Remdesivir is an antiviral nucleotide analogue used for therapy of severe novel coronavirus disease 2019 (COVID-19) caused by severe …
Baricitinib.
[No authors listed] [No authors listed] 2022 Aug 30. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. 2022 Aug 30. LiverTox®: Clinical and Research Information on Drug-Induced Liver Injury [Internet]. Bethesda (MD): National Institute of Diabetes and Digestive and Kidney Diseases; 2012–. PMID: 31643344 Free Books & Documents. Review.
Baricitinib is an orally available small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, severe alopecia areata, and, in combination with remdesivir, severe COVID-19 in hospitalized patients requiring supplementary oxygen. …
Baricitinib is an orally available small molecule inhibitor of Janus kinases that is used to treat moderate-to-severe rheumatoid arthritis, …
COVID-19 and acute kidney injury.
Ertuğlu LA, Kanbay A, Afşar B, Elsürer Afşar R, Kanbay M. Ertuğlu LA, et al. Tuberk Toraks. 2020 Dec;68(4):407-418. doi: 10.5578/tt.70010. Tuberk Toraks. 2020. PMID: 33448738 Free article. Review. English.
Current data show that many hospitalized COVID-19 patients suffer from kidney damage, in the form of proteinuria, hematuria or acute kidney injury (AKI). AKI is especially prevalent among severe and critically ill COVID-19 patients and is a predictor of morta …
Current data show that many hospitalized COVID-19 patients suffer from kidney damage, in the form of proteinuria, hematuria or acute …
Efficacy and Safety of Remdesivir in People With Impaired Kidney Function Hospitalized for COVID-19 Pneumonia: A Randomized Clinical Trial.
Sise ME, Santos JR, Goldman JD, Tuttle KR, Teixeira JP, Seibert AF, Koullias Y, Llewellyn J, Regan S, Zhao Y, Huang H, Hyland RH, Osinusi A, Winter H, Humeniuk R, Hulter HN, Gottlieb RL, Fusco DN, Birne R, Stancampiano FF, Libertin CR, Small CB, Plate M, McPhail MJ; REDPINE Investigators. Sise ME, et al. Clin Infect Dis. 2024 Nov 22;79(5):1172-1181. doi: 10.1093/cid/ciae333. Clin Infect Dis. 2024. PMID: 38913574 Free PMC article. Clinical Trial.
METHODS: In REDPINE, a phase 3, randomized, double-blind, placebo-controlled study, participants aged 12 years hospitalized for COVID-19 pneumonia with acute kidney injury, chronic kidney disease, or kidney failure were randomized 2:1 to receive intra …
METHODS: In REDPINE, a phase 3, randomized, double-blind, placebo-controlled study, participants aged 12 years hospitalized for COVID-19 pn …
130 results