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Page 1
Inpatient Management of Hyperemesis Gravidarum.
Clark SM, Zhang X, Goncharov DA. Clark SM, et al. Obstet Gynecol. 2024 Jun 1;143(6):745-758. doi: 10.1097/AOG.0000000000005518. Epub 2024 Feb 1. Obstet Gynecol. 2024. PMID: 38301258 Review.
Hyperemesis gravidarum has a reported incidence of approximately 0.3-3% of pregnancies. Without treatment, refractory hyperemesis gravidarum can result in dehydration, electrolyte deficiencies, and severe nutritional deficiencies, resulting in significant maternal morbidit …
Hyperemesis gravidarum has a reported incidence of approximately 0.3-3% of pregnancies. Without treatment, refractory hyperemesis gra …
Treatment options for hyperemesis gravidarum.
Abramowitz A, Miller ES, Wisner KL. Abramowitz A, et al. Arch Womens Ment Health. 2017 Jun;20(3):363-372. doi: 10.1007/s00737-016-0707-4. Epub 2017 Jan 9. Arch Womens Ment Health. 2017. PMID: 28070660 Free PMC article. Review.
Hyperemesis gravidarum (HG) is a severe and prolonged form of nausea and/or vomiting during pregnancy. HG affects 0.3-2% of pregnancies and is defined by dehydration, ketonuria, and more than 5% body weight loss. ...Mirtazapine is not associated with a …
Hyperemesis gravidarum (HG) is a severe and prolonged form of nausea and/or vomiting during pregnancy. HG affects 0.3-2% of …
Management Considerations for Recalcitrant Hyperemesis.
Spinosa D, Post A, Kuller JA, Dotters-Katz S. Spinosa D, et al. Obstet Gynecol Surv. 2020 Jan;75(1):50-60. doi: 10.1097/OGX.0000000000000746. Obstet Gynecol Surv. 2020. PMID: 31999353 Free article. Review.
IMPORTANCE: Hyperemesis gravidarum (HEG) affects 0.3% to 3% of pregnancies and requires additional therapies beyond those commonly used for less severe instances of nausea and vomiting of pregnancy (NVP). ...Postpyloric feeding approaches are less likely to i …
IMPORTANCE: Hyperemesis gravidarum (HEG) affects 0.3% to 3% of pregnancies and requires additional therapies beyond those commonly us …
Mirtazapine or ondansetron for hyperemesis gravidarum: a randomized placebo-controlled trial.
Ostenfeld A, Carlsen SE, Jensen AK, Futtrup TB, Westergaard HB, Pedersen LH, Andersen JT, Petersen TS, Løkkegaard ECL; VOMIT investigation group. Ostenfeld A, et al. Am J Obstet Gynecol. 2025 Dec 30:S0002-9378(25)00982-2. doi: 10.1016/j.ajog.2025.12.061. Online ahead of print. Am J Obstet Gynecol. 2025. PMID: 41478546 Free article.
The differences in Pregnancy Unique Quantification of Emesis 24 score change in mirtazapine vs both ondansetron and placebo were more evident after day 4. ...The incidence of mild to moderate adverse events was higher with mirtazapine, and serious adverse eve …
The differences in Pregnancy Unique Quantification of Emesis 24 score change in mirtazapine vs both ondansetron and placebo we …
Mirtazapine for Severe Nausea and Vomiting During Pregnancy: Case Presentations and Recommendations.
Khan AR, Stika CS, Wisner KL. Khan AR, et al. J Clin Psychopharmacol. 2025 Nov-Dec 01;45(6):629-633. doi: 10.1097/JCP.0000000000002067. Epub 2025 Aug 28. J Clin Psychopharmacol. 2025. PMID: 40874598
PURPOSE/BACKGROUND: Severe nausea and vomiting in pregnancy (sNVP) causes numerous detrimental short-term and long-term impacts on the physical and mental health of mothers and newborns, yet treatments are limited. When first-line drugs are ineffective, minimal data …
PURPOSE/BACKGROUND: Severe nausea and vomiting in pregnancy (sNVP) causes numerous detrimental short-term and long-term impact …
Adjuvants to Conventional Management of Postdural Puncture Headache Following Obstetric Surgery Under Spinal Anesthesia: Mirtazapine vs. Sumatriptan.
Ashoor TM, Abd ElKader AM, Gadalla RR, Esmat IM, Hasseb AM. Ashoor TM, et al. Pain Physician. 2025 Jan;28(1):39-49. Pain Physician. 2025. PMID: 39903014 Free article. Clinical Trial.
Every day at 8 p.m., patients in the mirtazapine group (the M-group) took 30 mg mirtazapine tablet, patients in the sumatriptan group (the S-group) took 50 mg sumatriptan tablet, and patients in the control group (the C-group) took placebo tablets. ...This study did …
Every day at 8 p.m., patients in the mirtazapine group (the M-group) took 30 mg mirtazapine tablet, patients in the sumatripta …
Common Questions About the Pharmacologic Management of Depression in Adults.
Kovich H, DeJong A. Kovich H, et al. Am Fam Physician. 2015 Jul 15;92(2):94-100. Am Fam Physician. 2015. PMID: 26176368 Free article. Review.
High-quality evidence is lacking on the benefits and harms of antidepressant use in pregnancy. It is unclear whether selective serotonin reuptake inhibitor use in breastfeeding mothers causes adverse effects in their infants, but sertraline and paroxetine transfer to breas …
High-quality evidence is lacking on the benefits and harms of antidepressant use in pregnancy. It is unclear whether selective seroto …
Low-dose mirtazapine in treatment of major depression developed following severe nausea and vomiting during pregnancy: two cases.
Uguz F. Uguz F. Gen Hosp Psychiatry. 2014 Jan-Feb;36(1):125.e5-6. doi: 10.1016/j.genhosppsych.2013.07.016. Epub 2013 Sep 10. Gen Hosp Psychiatry. 2014. PMID: 24034854
This report presents the successful use of low-dose mirtazapine in the treatment of major depression that developed following severe nausea and vomiting symptoms during the early gestational weeks in two cases. ...
This report presents the successful use of low-dose mirtazapine in the treatment of major depression that developed following severe …
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