Faecal microbial transfer and complex carbohydrates mediate protection against COPD.
Budden KF, Shukla SD, Bowerman KL, Vaughan A, Gellatly SL, Wood DLA, Lachner N, Idrees S, Rehman SF, Faiz A, Patel VK, Donovan C, Alemao CA, Shen S, Amorim N, Majumder R, Vanka KS, Mason J, Haw TJ, Tillet B, Fricker M, Keely S, Hansbro N, Belz GT, Horvat J, Ashhurst T, van Vreden C, McGuire H, Fazekas de St Groth B, King NJC, Crossett B, Cordwell SJ, Bonaguro L, Schultze JL, Hamilton-Williams EE, Mann E, Forster SC, Cooper MA, Segal LN, Chotirmall SH, Collins P, Bowman R, Fong KM, Yang IA, Wark PAB, Dennis PG, Hugenholtz P, Hansbro PM.
Budden KF, et al.
Gut. 2024 Apr 5;73(5):751-769. doi: 10.1136/gutjnl-2023-330521.
Gut. 2024.
PMID: 38331563
Clinical Trial.
Complex carbohydrates were assessed in mice using a high resistant starch diet, and in 16 patients with COPD using a randomised, double-blind, placebo-controlled pilot study of inulin supplementation. ...Proteomics and metabolomics identified downregulation of gluco …
Complex carbohydrates were assessed in mice using a high resistant starch diet, and in 16 patients with COPD using a randomise …