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Resistant starch decreases intrahepatic triglycerides in patients with NAFLD via gut microbiome alterations.
Ni Y, Qian L, Siliceo SL, Long X, Nychas E, Liu Y, Ismaiah MJ, Leung H, Zhang L, Gao Q, Wu Q, Zhang Y, Jia X, Liu S, Yuan R, Zhou L, Wang X, Li Q, Zhao Y, El-Nezami H, Xu A, Xu G, Li H, Panagiotou G, Jia W. Ni Y, et al. Cell Metab. 2023 Sep 5;35(9):1530-1547.e8. doi: 10.1016/j.cmet.2023.08.002. Cell Metab. 2023. PMID: 37673036 Free article. Clinical Trial.
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic dysfunction for which effective interventions are lacking. To investigate the effects of resistant starch (RS) as a microbiota-directed dietar
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic dysfunction for
Kudzu resistant starch effectively ameliorates non-alcoholic fatty liver disease by protecting the gut microbiota intestinal barrier and suppressing inflammatory responses.
Dong H, Yang X, Zhou Y, Yang M, Zhang H, Liu X, Zhu W. Dong H, et al. J Sci Food Agric. 2025 Sep;105(12):6538-6555. doi: 10.1002/jsfa.14371. Epub 2025 Jun 25. J Sci Food Agric. 2025. PMID: 40557534
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic steatohepatitis, may lead to a cocktail of disease consequences, for instance, type II diabetes, liver fibrosis, and even hepatocar …
BACKGROUND: Non-alcoholic fatty liver disease (NAFLD), including non-alcoholic steat …
Amelioratory Effect of Resistant Starch on Non-alcoholic Fatty Liver Disease via the Gut-Liver Axis.
Zhu W, Zhou Y, Tsao R, Dong H, Zhang H. Zhu W, et al. Front Nutr. 2022 May 17;9:861854. doi: 10.3389/fnut.2022.861854. eCollection 2022. Front Nutr. 2022. PMID: 35662935 Free PMC article. Review.
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome with a global prevalence. Impaired gut barrier function caused by an unhealthy diet plays a key role in disrupting the immune-metabolic homeostasis
Non-alcoholic fatty liver disease (NAFLD) is a hepatic manifestation of metabolic syndrome with a
Resistant starch from green banana (Musa sp.) attenuates non-alcoholic fat liver accumulation and increases short-chain fatty acids production in high-fat diet-induced obesity in mice.
Rosado CP, Rosa VHC, Martins BC, Soares AC, Santos IB, Monteiro EB, Moura-Nunes N, da Costa CA, Mulder ADRP, Daleprane JB. Rosado CP, et al. Int J Biol Macromol. 2020 Feb 15;145:1066-1072. doi: 10.1016/j.ijbiomac.2019.09.199. Epub 2019 Nov 13. Int J Biol Macromol. 2020. PMID: 31730978 Free article.
This study aimed to investigate the effect of resistant starch from green banana (GB) on steatosis and short-chain fatty acid (SCFAs) production in high fat diet-induced obesity in mice. ...Furthermore, the HFB fed-mice produced the highest amount of SCFAs (p …
This study aimed to investigate the effect of resistant starch from green banana (GB) on steatosis and short-chain fatty
The Protective Role of Butyrate against Obesity and Obesity-Related Diseases.
Coppola S, Avagliano C, Calignano A, Berni Canani R. Coppola S, et al. Molecules. 2021 Jan 28;26(3):682. doi: 10.3390/molecules26030682. Molecules. 2021. PMID: 33525625 Free PMC article. Review.
Obesity is the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular diseases, dyslipidemia, and non-alcoholic fatty liver disease. The common forms of obesity are multifactorial and derive from a complex interpla …
Obesity is the major predisposing factor to comorbidities, including type 2 diabetes, cardiovascular diseases, dyslipidemia, and non- …
Dietary Interventions in Metabolic Dysfunction-Associated Steatotic Liver Disease: A Narrative Review of Evidence, Mechanisms, and Translational Challenges.
Paredes-Marin A, He Y, Zhang X. Paredes-Marin A, et al. Nutrients. 2025 Nov 6;17(21):3491. doi: 10.3390/nu17213491. Nutrients. 2025. PMID: 41228562 Free PMC article.
A calorie-restricted lifestyle program in adults with MASLD (n = 196) reduced liver fat by 25% over 52 weeks. Resistant starch supplementation (n = 200) lowered intrahepatic triglyceride content by 8% through gut microbiome modulation. ...Conclusions: Dietary …
A calorie-restricted lifestyle program in adults with MASLD (n = 196) reduced liver fat by 25% over 52 weeks. Resistant sta
Commensal microbe-derived acetate suppresses NAFLD/NASH development via hepatic FFAR2 signalling in mice.
Aoki R, Onuki M, Hattori K, Ito M, Yamada T, Kamikado K, Kim YG, Nakamoto N, Kimura I, Clarke JM, Kanai T, Hase K. Aoki R, et al. Microbiome. 2021 Sep 16;9(1):188. doi: 10.1186/s40168-021-01125-7. Microbiome. 2021. PMID: 34530928 Free PMC article.
BACKGROUND: Non-alcoholic liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome, and it can progress to non-alcoholic steatohepatitis (NASH). ...Inulin consumption resulted in global changes in the gut microbiome …
BACKGROUND: Non-alcoholic liver disease (NAFLD) is the hepatic manifestation of metabolic syndrome, and i …
Mitigative effect of natural resistant starch from kudzu on intestinal-hepatic injury in mice exposed to high-fat diet and dextran sulfate sodium.
Dong H, Zhu F, Yang M, Zhang L, Liu X, Zhang H, Huang Y, Zhu W, Xie L. Dong H, et al. Int J Biol Macromol. 2026 Apr;353:151338. doi: 10.1016/j.ijbiomac.2026.151338. Epub 2026 Mar 10. Int J Biol Macromol. 2026. PMID: 41812947
Non-alcoholic fatty liver disease (NAFLD) has become a globally prevalent metabolic disorder, with its pathogenesis closely linked to dysfunction of the gut-liver axis. In this study, a mouse model of NAFLD was established b
Non-alcoholic fatty liver disease (NAFLD) has become a globally prevalent metabolic disorder, with
Pueraria lobata starch regulates gut microbiota and alleviates high-fat high-cholesterol diet induced non-alcoholic fatty liver disease in mice.
Yang Y, Li M, Wang Q, Huang H, Zhao Y, Du F, Chen Y, Shen J, Luo H, Zhao Q, Zeng J, Li W, Chen M, Li X, Wang F, Sun Y, Gu L, Xiao Z, Wu X. Yang Y, et al. Food Res Int. 2022 Jul;157:111401. doi: 10.1016/j.foodres.2022.111401. Epub 2022 May 26. Food Res Int. 2022. PMID: 35761655
This study showed that PLS consisted of mixed population of granules with polyhedral or spherical surface. The apparent content of resistant starch was 23.14%, and the molecular weight was 1.93 10(7) Da. PLS showed a branching degree and an average polymerization …
This study showed that PLS consisted of mixed population of granules with polyhedral or spherical surface. The apparent content of resist
Hepatoprotective potential of anthocyanins from purple highland barley bran against non-alcoholic fatty liver disease through gut-liver axis.
Zhang Y, Zhou Y, Fang G, Azi F, Gao Z, Wu F, Jiao L, Wang R, Lu B, Liu X. Zhang Y, et al. Food Res Int. 2026 Apr 30;230:118558. doi: 10.1016/j.foodres.2026.118558. Epub 2026 Feb 2. Food Res Int. 2026. PMID: 41794448
Non-alcoholic fatty liver disease (NAFLD) accounts for a major share of liver damage worldwide. ...Results indicated that PAE at 1.2 mg/mL significantly (p < 0.05) inhibited pancreatic lipase and cholesteryl esterase activities
Non-alcoholic fatty liver disease (NAFLD) accounts for a major share of liver damage worldw
14 results