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Year Number of Results
1949 1
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1957 4
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1962 1
1963 1
1981 1
1982 1
1983 5
1984 9
1985 11
1986 21
1987 15
1988 14
1989 15
1990 30
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1992 36
1993 32
1994 83
1995 165
1996 168
1997 181
1998 241
1999 371
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2001 407
2002 356
2003 416
2004 432
2005 505
2006 510
2007 514
2008 517
2009 501
2010 492
2011 549
2012 602
2013 579
2014 549
2015 538
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13,134 results

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Page 1
Trex1 prevents cell-intrinsic initiation of autoimmunity.
Stetson DB, Ko JS, Heidmann T, Medzhitov R. Stetson DB, et al. Cell. 2008 Aug 22;134(4):587-98. doi: 10.1016/j.cell.2008.06.032. Cell. 2008. PMID: 18724932 Free PMC article.
We show that single-stranded DNA derived from endogenous retroelements accumulates in Trex1-deficient cells, and that Trex1 can metabolize reverse-transcribed DNA. These findings reveal a cell-intrinsic mechanism for initiation of autoimmunity, implicate the ISD pathway as …
We show that single-stranded DNA derived from endogenous retroelements accumulates in Trex1-deficient cells, and that Trex1 can metab …
Genomic distribution of the retrovirus-like element ZAM in Drosophila.
Baldrich E, Dimitri P, Desset S, Leblanc P, Codipietro D, Vaury C. Baldrich E, et al. Genetica. 1997;100(1-3):131-40. Genetica. 1997. PMID: 9440265 Review.
The mobile element ZAM, recently identified in Drosophila melanogaster, is similar in structure and coding potential to vertebrate retroviruses. In this paper, we analyze the insertional and structural polymorphism of this element and show that members of this famil …
The mobile element ZAM, recently identified in Drosophila melanogaster, is similar in structure and coding potential to vertebrate re …
Mammalian retroelements.
Deininger PL, Batzer MA. Deininger PL, et al. Genome Res. 2002 Oct;12(10):1455-65. doi: 10.1101/gr.282402. Genome Res. 2002. PMID: 12368238 Free article. Review.
The majority of these elements utilize an RNA intermediate and are termed retroelements. Most of these retroelements appear to amplify in evolutionary waves that insert in the genome and then gradually diverge. In humans, almost half of the genome is recognizably de …
The majority of these elements utilize an RNA intermediate and are termed retroelements. Most of these retroelements appear to …
CircRNA-derived pseudogenes.
Dong R, Zhang XO, Zhang Y, Ma XK, Chen LL, Yang L. Dong R, et al. Cell Res. 2016 Jun;26(6):747-50. doi: 10.1038/cr.2016.42. Epub 2016 Mar 29. Cell Res. 2016. PMID: 27021280 Free PMC article. No abstract available.
Plant polyploidy and evolution.
Huang G, Zhu YX. Huang G, et al. J Integr Plant Biol. 2019 Jan;61(1):4-6. doi: 10.1111/jipb.12758. J Integr Plant Biol. 2019. PMID: 30548399 No abstract available.
Ty1 retrovirus-like element Gag contains overlapping restriction factor and nucleic acid chaperone functions.
Nishida Y, Pachulska-Wieczorek K, Błaszczyk L, Saha A, Gumna J, Garfinkel DJ, Purzycka KJ. Nishida Y, et al. Nucleic Acids Res. 2015 Sep 3;43(15):7414-31. doi: 10.1093/nar/gkv695. Epub 2015 Jul 8. Nucleic Acids Res. 2015. PMID: 26160887 Free PMC article.
Ty1 Gag comprises the capsid of virus-like particles and provides nucleic acid chaperone (NAC) functions during retrotransposition in budding yeast. A subgenomic Ty1 mRNA encodes a truncated Gag protein (p22) that is cleaved by Ty1 protease to form p18. p22/p18 strongly in …
Ty1 Gag comprises the capsid of virus-like particles and provides nucleic acid chaperone (NAC) functions during retrotransposition in …
SETDB1-Mediated Silencing of Retroelements.
Fukuda K, Shinkai Y. Fukuda K, et al. Viruses. 2020 May 30;12(6):596. doi: 10.3390/v12060596. Viruses. 2020. PMID: 32486217 Free PMC article. Review.
Among other H3K9 methyltransferases, SETDB1 and SETDB1-mediated H3K9 trimethylation (H3K9me3) play pivotal roles for silencing of endogenous and exogenous retroelements, thus contributing to genome stability against retroelement transposition. Furthermore, SETDB1 is highly …
Among other H3K9 methyltransferases, SETDB1 and SETDB1-mediated H3K9 trimethylation (H3K9me3) play pivotal roles for silencing of endogenous …
Accelerated Evolution by Diversity-Generating Retroelements.
Macadangdang BR, Makanani SK, Miller JF. Macadangdang BR, et al. Annu Rev Microbiol. 2022 Sep 8;76:389-411. doi: 10.1146/annurev-micro-030322-040423. Epub 2022 Jun 1. Annu Rev Microbiol. 2022. PMID: 35650669 Review.
Diversity-generating retroelements (DGRs) create vast amounts of targeted, functional diversity by facilitating the rapid evolution of ligand-binding protein domains. ...
Diversity-generating retroelements (DGRs) create vast amounts of targeted, functional diversity by facilitating the rapid evolution o …
The complete Tirant transposable element in Drosophila melanogaster shows a structural relationship with retrovirus-like retrotransposons.
Marsano RM, Moschetti R, Caggese C, Lanave C, Barsanti P, Caizzi R. Marsano RM, et al. Gene. 2000 Apr 18;247(1-2):87-95. doi: 10.1016/s0378-1119(00)00115-3. Gene. 2000. PMID: 10773447
It possesses three open reading frames (ORF) encoding Gag, Pol and Env proteins with a strong similarity with ZAM, a recently identified member of the gypsy class of retrovirus-like mobile elements. Molecular analysis of the Tirant genomic copies present in four D. …
It possesses three open reading frames (ORF) encoding Gag, Pol and Env proteins with a strong similarity with ZAM, a recently identified mem …
Plant centromeres.
Lamb JC, Yu W, Han F, Birchler JA. Lamb JC, et al. Genome Dyn. 2008;4:95-107. doi: 10.1159/000126009. Genome Dyn. 2008. PMID: 18756080
Plant centromeres are generally composed of tandem arrays of simple repeats that are typical of a particular species, but that evolve rapidly. Centromere specific retroelements are also present. These arrays associate with a centromere specific variant of histone H3 that a …
Plant centromeres are generally composed of tandem arrays of simple repeats that are typical of a particular species, but that evolve rapidl …
13,134 results
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