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Lingzhi or Reishi Medicinal Mushroom Ganoderma lucidum (Agaricomycetes) Nanogel in a Complete Freund's Adjuvant-Induced Rheumatoid Arthritis Rat Model: Anti-Arthritic, Anti-Inflammatory, and Antioxidative Activity.
Ratnaningtyas NI, Husen F, Fitrianto N. Ratnaningtyas NI, et al. Int J Med Mushrooms. 2024;26(8):27-40. doi: 10.1615/IntJMedMushrooms.2024053884. Int J Med Mushrooms. 2024. PMID: 38967209
Lingzhi or reishi mushroom, Ganoderma lucidum, is a medicinal mushroom quite widely developed as herbal medicine because it has acted as an anticancer, antitumor, antioxidant, and anti-inflammatory. The active mycochemical compounds of G. lucidum mushrooms, such as flavono …
Lingzhi or reishi mushroom, Ganoderma lucidum, is a medicinal mushroom quite widely developed as herbal medicine because it has acted …
Ganoderma lucidum polysaccharide peptide (GLPP) attenuates rheumatic arthritis in rats through inactivating NF-kappaB and MAPK signaling pathways.
Meng M, Wang L, Yao Y, Lin D, Wang C, Yao J, Sun H, Liu M. Meng M, et al. Phytomedicine. 2023 Oct;119:155010. doi: 10.1016/j.phymed.2023.155010. Epub 2023 Aug 2. Phytomedicine. 2023. PMID: 37586160
BACKGROUND: Not many drugs with fewer side effects are available for the treatment of rheumatoid arthritis (RA). Ganoderma lucidum polysaccharide peptide (GLPP) has good immunomodulatory effects, but whether it is effective in managing RA is not clear. ...Paw …
BACKGROUND: Not many drugs with fewer side effects are available for the treatment of rheumatoid arthritis (RA). Ganoderma …
Potential Anti-Rheumatoid Arthritis Activities and Mechanisms of Ganoderma lucidum Polysaccharides.
Meng M, Yao J, Zhang Y, Sun H, Liu M. Meng M, et al. Molecules. 2023 Mar 8;28(6):2483. doi: 10.3390/molecules28062483. Molecules. 2023. PMID: 36985456 Free PMC article. Review.
Rheumatoid arthritis (RA) is a chronic and autoimmune disease characterized by inflammation, autoimmune dysfunction, and cartilage and bone destruction. In this review, we summarized the available reports on the protective effects of Ganoderma lucidum polysac …
Rheumatoid arthritis (RA) is a chronic and autoimmune disease characterized by inflammation, autoimmune dysfunction, and carti …
Inhibitory effects of Ganoderma lucidum spore oil on rheumatoid arthritis in a collagen-induced arthritis mouse model.
Heo Y, Kim M, Suminda GGD, Min Y, Zhao Y, Ghosh M, Son YO. Heo Y, et al. Biomed Pharmacother. 2023 Jan;157:114067. doi: 10.1016/j.biopha.2022.114067. Epub 2022 Dec 5. Biomed Pharmacother. 2023. PMID: 36481405 Free article.
Holistic healthcare practitioners have now started to focus on specific traditional medicinal mushrooms to treat rheumatoid arthritis (RA). Ganoderma lucidum (GL) is one of the oldest mushrooms that have been used in ancient Chinese medicine to treat inflamma …
Holistic healthcare practitioners have now started to focus on specific traditional medicinal mushrooms to treat rheumatoid arthri …
Ganoderic acid A improves osteoarthritis by regulating RANKL/OPG ratio.
Wu W, Song K, Chen G, Liu N, Cao T. Wu W, et al. Chem Biol Drug Des. 2022 Sep;100(3):313-319. doi: 10.1111/cbdd.14101. Epub 2022 Jun 28. Chem Biol Drug Des. 2022. PMID: 35708158
Ganoderma mushrooms have been used to treat rheumatoid arthritis (RA) in East Asia. Whether Ganoderic acid A (GAA), the natural product extracted from Ganoderma, could be utilized to alleviate osteoarthritis (OA) is investigated in this study. ...
Ganoderma mushrooms have been used to treat rheumatoid arthritis (RA) in East Asia. Whether Ganoderic acid A (GAA), the …
Do recent research studies validate the medicinal plants used in British Columbia, Canada for pet diseases and wild animals taken into temporary care?
Lans C. Lans C. J Ethnopharmacol. 2019 May 23;236:366-392. doi: 10.1016/j.jep.2019.02.030. Epub 2019 Feb 15. J Ethnopharmacol. 2019. PMID: 30772483 Review.
Dogs were also treated with medicinal plants for rheumatoid arthritis, joint pain and articular cartilage injuries. More than 40 plants were used. ...Arctium lappa, Hydrangea arborescens and Lactuca muralis were used for rheumatoid arthritis and joint …
Dogs were also treated with medicinal plants for rheumatoid arthritis, joint pain and articular cartilage injuries. More than …
Ganomycin I from Ganoderma lucidum attenuates RANKL-mediated osteoclastogenesis by inhibiting MAPKs and NFATc1.
Tran PT, Dat NT, Dang NH, Van Cuong P, Lee S, Hwangbo C, Van Minh C, Lee JH. Tran PT, et al. Phytomedicine. 2019 Mar 1;55:1-8. doi: 10.1016/j.phymed.2018.10.029. Epub 2018 Oct 25. Phytomedicine. 2019. PMID: 30668419
BACKGROUND: Many bone-related diseases such as osteoporosis and rheumatoid arthritis are commonly associated with excessive activity of the osteoclast. Ganomycin I (GMI), a meroterpenoid isolated from Vietnamese mushroom Ganoderma lucidum, possesses a variety …
BACKGROUND: Many bone-related diseases such as osteoporosis and rheumatoid arthritis are commonly associated with excessive ac …
Immunomodulatory proteins FIP-gts and chloroquine induce caspase-independent cell death via autophagy for resensitizing cisplatin-resistant urothelial cancer cells.
Hsin IL, Wang SC, Li JR, Ciou TC, Wu CH, Wu HM, Ko JL. Hsin IL, et al. Phytomedicine. 2016 Dec 1;23(13):1566-1573. doi: 10.1016/j.phymed.2016.09.003. Epub 2016 Sep 10. Phytomedicine. 2016. PMID: 27823620
BACKGROUND: Chloroquine, a lysosomal inhibitor, is used for malaria, rheumatoid arthritis, and lupus erythematosus therapy. In our previous study, FIP-gts, an immunomodulatory protein from Ganoderma tsugae, inhibited cell viability in lung cancer cells and ur …
BACKGROUND: Chloroquine, a lysosomal inhibitor, is used for malaria, rheumatoid arthritis, and lupus erythematosus therapy. In …
Suppression of inflammatory and allergic responses by pharmacologically potent fungus Ganoderma lucidum.
Bhardwaj N, Katyal P, Sharma AK. Bhardwaj N, et al. Recent Pat Inflamm Allergy Drug Discov. 2014;8(2):104-17. doi: 10.2174/1872213x08666140619110657. Recent Pat Inflamm Allergy Drug Discov. 2014. PMID: 24948193 Review.
Whereas, chronic inflammation can be correlated well with the onset of a plethora of autoimmune disorders; rheumatoid arthritis, systemic lupus and polymyalgia, rheumatic and other diseases like asthma, inflammatory bowel diseases, cardiovascular disorders, ulcerati …
Whereas, chronic inflammation can be correlated well with the onset of a plethora of autoimmune disorders; rheumatoid arthritis …
Effects of Ganoderma lucidum spores on sialoadenitis of nonobese diabetic mice.
Qi G, Hua H, Gao Y, Lin Q, Yu GY. Qi G, et al. Chin Med J (Engl). 2009 Mar 5;122(5):556-60. Chin Med J (Engl). 2009. PMID: 19323907
The aim of this study was to investigate the effects of Ganoderma lucindum spores (GLS) on sialoadenitis of nonobese diabetic (NOD) mice. METHODS: Thirty-two female NOD mice were assigned randomly into 4 groups: low-dose GLS-treated (L-GLS) group and high-dose GLS-treated …
The aim of this study was to investigate the effects of Ganoderma lucindum spores (GLS) on sialoadenitis of nonobese diabetic (NOD) m …
Analgesic and anti-arthritic effects of Lingzhi and San Miao San supplementation in a rat model of arthritis induced by Freund's complete adjuvant.
Lam FF, Ko IW, Ng ES, Tam LS, Leung PC, Li EK. Lam FF, et al. J Ethnopharmacol. 2008 Oct 30;120(1):44-50. doi: 10.1016/j.jep.2008.07.028. Epub 2008 Jul 30. J Ethnopharmacol. 2008. PMID: 18708134
AIM OF STUDY: In this study, we have investigated the analgesic and anti-arthritic effects of a traditional Chinese medicine (TCM) combination of Lingzhi and San Miao San (SMS) in a rat model of arthritis induced by Freund's complete adjuvant (FCA). MATERIALS AND METHODS: …
AIM OF STUDY: In this study, we have investigated the analgesic and anti-arthritic effects of a traditional Chinese medicine (TCM) combinati …
Safety and efficacy of Ganoderma lucidum (lingzhi) and San Miao San supplementation in patients with rheumatoid arthritis: a double-blind, randomized, placebo-controlled pilot trial.
Li EK, Tam LS, Wong CK, Li WC, Lam CW, Wachtel-Galor S, Benzie IF, Bao YX, Leung PC, Tomlinson B. Li EK, et al. Arthritis Rheum. 2007 Oct 15;57(7):1143-50. doi: 10.1002/art.22994. Arthritis Rheum. 2007. PMID: 17907228 Free article. Clinical Trial.
OBJECTIVE: To examine the efficacy of popular Chinese herbs used in a traditional Chinese medicine (TCM) combination of Ganoderma lucidum and San Miao San (SMS), with purported diverse health benefits including antioxidant properties in rheumatoid arthritis ( …
OBJECTIVE: To examine the efficacy of popular Chinese herbs used in a traditional Chinese medicine (TCM) combination of Ganoderma luc …
Ganoderma lucidum polysaccharide peptide reduced the production of proinflammatory cytokines in activated rheumatoid synovial fibroblast.
Ho YW, Yeung JS, Chiu PK, Tang WM, Lin ZB, Man RY, Lau CS. Ho YW, et al. Mol Cell Biochem. 2007 Jul;301(1-2):173-9. doi: 10.1007/s11010-006-9409-y. Epub 2007 Jan 12. Mol Cell Biochem. 2007. PMID: 17219061
The aim of the current study was to elucidate the potential therapeutic effect of Ganoderma lucidum polysaccharide peptide (GL-PP) in rheumatoid arthritis (RA). The effects of GL-PP on cell proliferation and cytokine production were studied in RA synovial fib …
The aim of the current study was to elucidate the potential therapeutic effect of Ganoderma lucidum polysaccharide peptide (GL-PP) in …
Immunomodulatory effects of lingzhi and san-miao-san supplementation on patients with rheumatoid arthritis.
Bao YX, Wong CK, Li EK, Tam LS, Leung PC, Yin YB, Lam CW. Bao YX, et al. Immunopharmacol Immunotoxicol. 2006;28(2):197-200. doi: 10.1080/08923970600815097. Immunopharmacol Immunotoxicol. 2006. PMID: 16873089
Rheumatoid arthritis (RA) is an autoimmune joint disease. We evaluated a standard preparation of Lingzhi (Ganoderma lucidum) and San-Miao-San (Rhizoma atractylodis, Cortex phellodendri, Radix achyranthes bidentatae) capsules (TCM group) for its supplementary …
Rheumatoid arthritis (RA) is an autoimmune joint disease. We evaluated a standard preparation of Lingzhi (Ganoderma luc …