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Rhodiola rosea: A Therapeutic Candidate on Cardiovascular Diseases.
Chen Y, Tang M, Yuan S, Fu S, Li Y, Li Y, Wang Q, Cao Y, Liu L, Zhang Q. Chen Y, et al. Oxid Med Cell Longev. 2022 Feb 27;2022:1348795. doi: 10.1155/2022/1348795. eCollection 2022. Oxid Med Cell Longev. 2022. PMID: 35265260 Free PMC article. Review.
Rhodiola rosea has various chemical components, and different chemical elements have the same pharmacological effects and medicinal values for various cardiovascular diseases. This article reviews the research on the pharmacological effects of Rhodiola rosea on card …
Rhodiola rosea has various chemical components, and different chemical elements have the same pharmacological effects and medicinal v …
Rhodiola and salidroside in the treatment of metabolic disorders.
Bai XL, Deng XL, Wu GJ, Li WJ, Jin S. Bai XL, et al. Mini Rev Med Chem. 2019;19(19):1611-1626. doi: 10.2174/1389557519666190903115424. Mini Rev Med Chem. 2019. PMID: 31481002 Review.
Extracts of Rhodiola and salidroside, the most abundant active compound in Rhodiola, are suggested to provide a beneficial effect in mental, behavioral, and metabolic disorders. ...This review highlights studies that focus on the potential role of Rhodiola ex …
Extracts of Rhodiola and salidroside, the most abundant active compound in Rhodiola, are suggested to provide a beneficial eff …
Anti-atherosclerosis of oligomeric proanthocyanidins from Rhodiola rosea on rat model via hypolipemic, antioxidant, anti-inflammatory activities together with regulation of endothelial function.
Zhou Q, Han X, Li R, Zhao W, Bai B, Yan C, Dong X. Zhou Q, et al. Phytomedicine. 2018 Dec 1;51:171-180. doi: 10.1016/j.phymed.2018.10.002. Epub 2018 Oct 4. Phytomedicine. 2018. PMID: 30466614
BACKGROUND: Rhodiola rosea has been used as a traditional medicine for a long history. ...HYPOTHESIS/PURPOSE: We hypothesized that OPCRR can improve the atherosclerosis pathological in rats. In the present study, we investigated the effects of OPCRR on the serum lip …
BACKGROUND: Rhodiola rosea has been used as a traditional medicine for a long history. ...HYPOTHESIS/PURPOSE: We hypothesized that OP …
Salidroside Decreases Atherosclerosis Plaque Formation via Inhibiting Endothelial Cell Pyroptosis.
Xing SS, Yang J, Li WJ, Li J, Chen L, Yang YT, Lei X, Li J, Wang K, Liu X. Xing SS, et al. Inflammation. 2020 Apr;43(2):433-440. doi: 10.1007/s10753-019-01106-x. Inflammation. 2020. PMID: 32076940
However, the effect of SAL on atherosclerosis-related pyroptosis has not been studied. Here, we investigated the effect of SAL on pyroptosis to explain the underlying mechanisms of SAL on atherosclerosis-related inflammation. We established an atherosclerosis …
However, the effect of SAL on atherosclerosis-related pyroptosis has not been studied. Here, we investigated the effect of SAL on pyr …
Pharmacological functions of salidroside in renal diseases: facts and perspectives.
Liu Q, Chen J, Zeng A, Song L. Liu Q, et al. Front Pharmacol. 2024 Jan 8;14:1309598. doi: 10.3389/fphar.2023.1309598. eCollection 2023. Front Pharmacol. 2024. PMID: 38259279 Free PMC article. Review.
Rhodiola rosea is a valuable functional medicinal plant widely utilized in China and other Asian countries for its anti-fatigue, anti-aging, and altitude sickness prevention properties. Salidroside, a most active constituent derived from Rhodiola rosea, exhibits pot …
Rhodiola rosea is a valuable functional medicinal plant widely utilized in China and other Asian countries for its anti-fatigue, anti …
Salidroside Ameliorated Intermittent Hypoxia-Aggravated Endothelial Barrier Disruption and Atherosclerosis via the cAMP/PKA/RhoA Signaling Pathway.
Li L, Yang Y, Zhang H, Du Y, Jiao X, Yu H, Wang Y, Lv Q, Li F, Sun Q, Qin Y. Li L, et al. Front Pharmacol. 2021 Aug 24;12:723922. doi: 10.3389/fphar.2021.723922. eCollection 2021. Front Pharmacol. 2021. PMID: 34504429 Free PMC article.
Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sleep apnea-hypopnea syndrome is chronic intermittent hypoxia (IH), which induces reactive oxygen species (ROS) overproduction, endothelial bar …
Background: Endothelial barrier dysfunction plays a key role in atherosclerosis progression. The primary pathology of obstructive sle …
Tyrosol attenuates lipopolysaccharide-induced inflammation in HUVECs to promote vascular health against atherosclerosis challenge.
Zhao W, Wei H, Lu J, Sha W, Sun D, Pan T, Lei T. Zhao W, et al. Exp Ther Med. 2023 Apr 6;25(5):240. doi: 10.3892/etm.2023.11939. eCollection 2023 May. Exp Ther Med. 2023. PMID: 37114177 Free PMC article.
Inflammation serves a key role in the development of vascular diseases, such as atherosclerosis. Tyrosol is a natural polyphenolic compound with diverse biological functions, found in large quantities in olive oil or in Rhodiola rosea. ...
Inflammation serves a key role in the development of vascular diseases, such as atherosclerosis. Tyrosol is a natural polyphenolic co …
The Therapeutic Effects and Mechanisms of Salidroside on Cardiovascular and Metabolic Diseases: An Updated Review.
Zhao CC, Wu XY, Yi H, Chen R, Fan G. Zhao CC, et al. Chem Biodivers. 2021 Jul;18(7):e2100033. doi: 10.1002/cbdv.202100033. Epub 2021 Jun 8. Chem Biodivers. 2021. PMID: 33991395 Review.
Salidroside (SAL), a phenylpropane glycoside, is the main active ingredient of the plateau plant Rhodiola. So far, many animal experiments proved that SAL has good biological activity against some metabolic and cardiovascular diseases. ...This review systematically summari …
Salidroside (SAL), a phenylpropane glycoside, is the main active ingredient of the plateau plant Rhodiola. So far, many animal experi …
Salidroside simultaneously reduces de novo lipogenesis and cholesterol biosynthesis to attenuate atherosclerosis in mice.
Song T, Wang P, Li C, Jia L, Liang Q, Cao Y, Dong P, Shi H, Jiang M. Song T, et al. Biomed Pharmacother. 2021 Feb;134:111137. doi: 10.1016/j.biopha.2020.111137. Epub 2020 Dec 16. Biomed Pharmacother. 2021. PMID: 33341055 Free article.
Salidroside is a kind of phenylethanoid glycoside and widespread in the plants from Rhodiola and Ligustrum species. Our previous study has reported that salidroside can prevent atherosclerosis progression by ameliorating glyerolipid and glycerophospholipid metabolis …
Salidroside is a kind of phenylethanoid glycoside and widespread in the plants from Rhodiola and Ligustrum species. Our previous stud …
Salidroside improves endothelial function and alleviates atherosclerosis by activating a mitochondria-related AMPK/PI3K/Akt/eNOS pathway.
Xing SS, Yang XY, Zheng T, Li WJ, Wu D, Chi JY, Bian F, Bai XL, Wu GJ, Zhang YZ, Zhang CT, Zhang YH, Li YS, Jin S. Xing SS, et al. Vascul Pharmacol. 2015 Sep;72:141-52. doi: 10.1016/j.vph.2015.07.004. Epub 2015 Jul 15. Vascul Pharmacol. 2015. PMID: 26187353
Given the importance of endothelial nitric oxide synthase (eNOS) in atherosclerosis, we sought to elucidate whether SAL could stimulate eNOS activation and also to explore its upstream signaling pathway. ...Taken together, our data described the effects of SAL on mitochond …
Given the importance of endothelial nitric oxide synthase (eNOS) in atherosclerosis, we sought to elucidate whether SAL could stimula …
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