Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1948 1
1981 1
1992 1
1994 2
1995 1
1997 1
1998 5
1999 5
2000 4
2001 3
2002 5
2003 1
2004 7
2005 3
2006 5
2007 2
2008 6
2009 5
2010 9
2011 3
2012 5
2013 3
2014 7
2015 8
2016 4
2017 5
2018 6
2019 7
2020 6
2021 9
2022 13
2023 6
2024 9
2025 6
2026 5

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

157 results

Results by year

Filters applied: . Clear all
Page 1
Supplementation with Riboflavin (Vitamin B2) for Migraine Prophylaxis in Adults and Children: A Review.
Namazi N, Heshmati J, Tarighat-Esfanjani A. Namazi N, et al. Int J Vitam Nutr Res. 2015;85(1-2):79-87. doi: 10.1024/0300-9831/a000225. Int J Vitam Nutr Res. 2015. PMID: 26780280 Free article. Review.
Low vitamin B2 can lead to mitochondrial dysfunction and may have an effect on migraine pathogenesis. The aim of the present study was to carry out a review of existing evidence regarding the effects of riboflavin (vitamin B2) supplementation on migraine prop …
Low vitamin B2 can lead to mitochondrial dysfunction and may have an effect on migraine pathogenesis. The aim of the present study wa …
Improvement of migraine symptoms with a proprietary supplement containing riboflavin, magnesium and Q10: a randomized, placebo-controlled, double-blind, multicenter trial.
Gaul C, Diener HC, Danesch U; Migravent® Study Group. Gaul C, et al. J Headache Pain. 2015;16:516. doi: 10.1186/s10194-015-0516-6. Epub 2015 Apr 3. J Headache Pain. 2015. PMID: 25916335 Free PMC article. Clinical Trial.
BACKGROUND: Non-medical, non-pharmacological and pharmacological treatments are recommended for the prevention of migraine. The purpose of this randomized double-blind placebo controlled, multicenter trial was to evaluate the efficacy of a proprietary nutritional supplemen …
BACKGROUND: Non-medical, non-pharmacological and pharmacological treatments are recommended for the prevention of migraine. The purpo …
Preventive Migraine Treatment.
Silberstein SD. Silberstein SD. Continuum (Minneap Minn). 2015 Aug;21(4 Headache):973-89. doi: 10.1212/CON.0000000000000199. Continuum (Minneap Minn). 2015. PMID: 26252585 Free PMC article. Review.
PURPOSE OF REVIEW: This article reviews the evidence base for the preventive treatment of migraine. RECENT FINDINGS: Evidence-based guidelines for the preventive treatment of migraine have recently been published by the American Academy of Neurology (AAN) and the Ca …
PURPOSE OF REVIEW: This article reviews the evidence base for the preventive treatment of migraine. RECENT FINDINGS: Evidence-based g …
Migraine Headache Prophylaxis.
Ha H, Gonzalez A. Ha H, et al. Am Fam Physician. 2019 Jan 1;99(1):17-24. Am Fam Physician. 2019. PMID: 30600979 Free article.
Migraines impose significant health and financial burdens. Approximately 38% of patients with episodic migraines would benefit from preventive therapy, but less than 13% take prophylactic medications. Preventive medication therapy reduces migraine frequency, …
Migraines impose significant health and financial burdens. Approximately 38% of patients with episodic migraines would benefit …
Prophylaxis of migraine headaches with riboflavin: A systematic review.
Thompson DF, Saluja HS. Thompson DF, et al. J Clin Pharm Ther. 2017 Aug;42(4):394-403. doi: 10.1111/jcpt.12548. Epub 2017 May 8. J Clin Pharm Ther. 2017. PMID: 28485121
The purpose of this study was to provide a systematic review of the current role of riboflavin in the prophylaxis of migraine headache. METHODS: A MEDLINE literature search inclusive of the dates 1966-2016 was performed using the search terms: riboflavin and …
The purpose of this study was to provide a systematic review of the current role of riboflavin in the prophylaxis of migraine …
Effect of Vitamin B2 supplementation on migraine prophylaxis: a systematic review and meta-analysis.
Chen YS, Lee HF, Tsai CH, Hsu YY, Fang CJ, Chen CJ, Hung YH, Hu FW. Chen YS, et al. Nutr Neurosci. 2022 Sep;25(9):1801-1812. doi: 10.1080/1028415X.2021.1904542. Epub 2021 Mar 29. Nutr Neurosci. 2022. PMID: 33779525
OBJECTIVE: Migraine is a common disease worldwide and migraine prevention is primarily currently based on pharmaceuticals. The mechanism of Vitamin B2 may positively contribute to migraine. This systematic review and meta-analysis aimed to evaluate the impact …
OBJECTIVE: Migraine is a common disease worldwide and migraine prevention is primarily currently based on pharmaceuticals. The …
Riboflavin Has Neuroprotective Potential: Focus on Parkinson's Disease and Migraine.
Marashly ET, Bohlega SA. Marashly ET, et al. Front Neurol. 2017 Jul 20;8:333. doi: 10.3389/fneur.2017.00333. eCollection 2017. Front Neurol. 2017. PMID: 28775706 Free PMC article. Review.
In conclusion, riboflavin is a potential neuroprotective agent affecting a wide range of neurological disorders exemplified by PD, a disorder of neurodegeneration, and migraine headache, a disorder of pain. In this article, we will emphasize the role of ri …
In conclusion, riboflavin is a potential neuroprotective agent affecting a wide range of neurological disorders exemplified by …
Effects of selected dietary supplements on migraine prophylaxis: A systematic review and dose-response meta-analysis of randomized controlled trials.
Talandashti MK, Shahinfar H, Delgarm P, Jazayeri S. Talandashti MK, et al. Neurol Sci. 2025 Feb;46(2):651-670. doi: 10.1007/s10072-024-07794-0. Epub 2024 Oct 15. Neurol Sci. 2025. PMID: 39404918
BACKGROUND: The existing evidence on the effect of dietary supplements for preventing migraines has generated conflicting results. METHODS: We assessed alterations in migraine clinical features corresponding to the intake of dietary supplements. ...Probiotics decrea …
BACKGROUND: The existing evidence on the effect of dietary supplements for preventing migraines has generated conflicting results. ME …
Nutraceuticals and Headache 2024: Riboflavin, Coenzyme Q10, Feverfew, Magnesium, Melatonin, and Butterbur.
Tepper SJ, Tepper K. Tepper SJ, et al. Curr Pain Headache Rep. 2025 Jan 24;29(1):33. doi: 10.1007/s11916-025-01358-3. Curr Pain Headache Rep. 2025. PMID: 39853578 Review.
Nutraceuticals are not regulated by the US Food and Drug Administration, so a careful literature review is essential to make clinical decisions. Riboflavin or vitamin B2 can be recommended for migraine prevention in adults, but pediatric use is not proven. ...Coenzy …
Nutraceuticals are not regulated by the US Food and Drug Administration, so a careful literature review is essential to make clinical decisi …
The Brain, the Eating Plate, and the Gut Microbiome: Partners in Migraine Pathogenesis.
Gazerani P, Papetti L, Dalkara T, Cook CL, Webster C, Bai J. Gazerani P, et al. Nutrients. 2024 Jul 11;16(14):2222. doi: 10.3390/nu16142222. Nutrients. 2024. PMID: 39064664 Free PMC article. Review.
This review summarizes the relationship between diet, the gut microbiome, and migraine. Key findings reveal that certain dietary factors, such as caffeine and alcohol, can trigger migraine, while nutrients like magnesium and riboflavin may help alleviate m …
This review summarizes the relationship between diet, the gut microbiome, and migraine. Key findings reveal that certain dietary fact …
157 results