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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1975 1
1977 3
1978 2
1979 3
1980 2
1981 3
1982 3
1983 2
1984 4
1985 1
1986 1
1987 3
1988 5
1990 2
1991 1
1993 2
1994 4
1995 4
1996 5
1997 3
1998 6
1999 6
2000 3
2001 8
2002 14
2003 13
2004 20
2005 19
2006 12
2007 16
2008 22
2009 30
2010 38
2011 43
2012 42
2013 37
2014 45
2015 27
2016 37
2017 40
2018 39
2019 38
2020 45
2021 35
2022 31
2023 33
2024 30
2025 38
2026 19

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764 results

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Page 1
Assembly of the small ribosomal subunit in yeast: mechanism and regulation.
Chaker-Margot M. Chaker-Margot M. RNA. 2018 Jul;24(7):881-891. doi: 10.1261/rna.066985.118. Epub 2018 Apr 30. RNA. 2018. PMID: 29712726 Free PMC article. Review.
The biogenesis of the small ribosomal subunit, or 40S, is especially intricate, requiring more than four times the mass of the small subunit in assembly factors for its full maturation. ...Mechanisms of the regulation of ribosome
The biogenesis of the small ribosomal subunit, or 40S, is especially intricate, requiring more than four times the mass …
Eukaryotic Ribosome Assembly.
Vanden Broeck A, Klinge S. Vanden Broeck A, et al. Annu Rev Biochem. 2024 Aug;93(1):189-210. doi: 10.1146/annurev-biochem-030222-113611. Epub 2024 Jul 2. Annu Rev Biochem. 2024. PMID: 38768392 Free article. Review.
During the last ten years, developments in cryo-electron microscopy have transformed our understanding of eukaryotic ribosome assembly. As a result, the field has advanced from a list of the vast array of ribosome assembly factors toward an emerging mo …
During the last ten years, developments in cryo-electron microscopy have transformed our understanding of eukaryotic ribosome asse
Translation in Prokaryotes.
Rodnina MV. Rodnina MV. Cold Spring Harb Perspect Biol. 2018 Sep 4;10(9):a032664. doi: 10.1101/cshperspect.a032664. Cold Spring Harb Perspect Biol. 2018. PMID: 29661790 Free PMC article. Review.
Correct codon-anticodon interaction during the decoding phase of elongation results in major conformational changes of the small ribosomal subunit and shapes the reaction pathway of guanosine triphosphate (GTP) hydrolysis. ...Following termination, the rib
Correct codon-anticodon interaction during the decoding phase of elongation results in major conformational changes of the small r
Assembly and structure of the SSU processome-a nucleolar precursor of the small ribosomal subunit.
Barandun J, Hunziker M, Klinge S. Barandun J, et al. Curr Opin Struct Biol. 2018 Apr;49:85-93. doi: 10.1016/j.sbi.2018.01.008. Epub 2018 Feb 4. Curr Opin Struct Biol. 2018. PMID: 29414516 Free PMC article. Review.
The small subunit processome is the first precursor of the small eukaryotic ribosomal subunit. ...Large rearrangements within the SSU processome are required for compaction into the mature small ribosomal subunit....
The small subunit processome is the first precursor of the small eukaryotic ribosomal subunit. ...Large r …
Principles of mitoribosomal small subunit assembly in eukaryotes.
Harper NJ, Burnside C, Klinge S. Harper NJ, et al. Nature. 2023 Feb;614(7946):175-181. doi: 10.1038/s41586-022-05621-0. Epub 2022 Dec 8. Nature. 2023. PMID: 36482135 Free PMC article.
Here we used cryo-electron microscopy to determine nine structures of native yeast and human mitoribosomal small subunit assembly intermediates, illuminating the mechanistic basis for how GTPases are used to control early steps of decoding centre formation, h …
Here we used cryo-electron microscopy to determine nine structures of native yeast and human mitoribosomal small subunit as
Protein Assistants of Small Ribosomal Subunit Biogenesis in Bacteria.
Maksimova E, Kravchenko O, Korepanov A, Stolboushkina E. Maksimova E, et al. Microorganisms. 2022 Mar 30;10(4):747. doi: 10.3390/microorganisms10040747. Microorganisms. 2022. PMID: 35456798 Free PMC article. Review.
Ribosome biogenesis is a fundamental and multistage process. The basic steps of ribosome assembly are the transcription, processing, folding, and modification of rRNA; the translation, folding, and modification of r-proteins; and consecutive binding of rib
Ribosome biogenesis is a fundamental and multistage process. The basic steps of ribosome assembly are the transcription
Principles of 60S ribosomal subunit assembly emerging from recent studies in yeast.
Konikkat S, Woolford JL Jr. Konikkat S, et al. Biochem J. 2017 Jan 15;474(2):195-214. doi: 10.1042/BCJ20160516. Biochem J. 2017. PMID: 28062837 Free PMC article. Review.
The efficiency and fidelity of ribosome biogenesis are facilitated by >200 assembly factors and 76 different small nucleolar RNAs. The pathway is driven forward by numerous remodeling events to rearrange the ribonucleoprotein architecture of pre-ribosomes …
The efficiency and fidelity of ribosome biogenesis are facilitated by >200 assembly factors and 76 different small
KsgA facilitates ribosomal small subunit maturation by proofreading a key structural lesion.
Sun J, Kinman LF, Jahagirdar D, Ortega J, Davis JH. Sun J, et al. Nat Struct Mol Biol. 2023 Oct;30(10):1468-1480. doi: 10.1038/s41594-023-01078-5. Epub 2023 Aug 31. Nat Struct Mol Biol. 2023. PMID: 37653244 Free PMC article.
Ribosome assembly is orchestrated by many assembly factors, including ribosomal RNA methyltransferases, whose precise role is poorly understood. Here, we leverage the power of cryo-EM and machine learning to discover that the E. coli methyltransferase
Ribosome assembly is orchestrated by many assembly factors, including ribosomal RNA methyltransferases, whose pr
Mechanism of mitoribosomal small subunit biogenesis and preinitiation.
Itoh Y, Khawaja A, Laptev I, Cipullo M, Atanassov I, Sergiev P, Rorbach J, Amunts A. Itoh Y, et al. Nature. 2022 Jun;606(7914):603-608. doi: 10.1038/s41586-022-04795-x. Epub 2022 Jun 8. Nature. 2022. PMID: 35676484 Free PMC article.
Here we use cryo-electron microscopy to determine a series of the small mitoribosomal subunit (SSU) intermediates in complex with auxiliary factors, revealing a sequential assembly mechanism. ...The new conformation allows initiation factor mtIF3 to already o …
Here we use cryo-electron microscopy to determine a series of the small mitoribosomal subunit (SSU) intermediates in complex w …
Role of Era in assembly and homeostasis of the ribosomal small subunit.
Razi A, Davis JH, Hao Y, Jahagirdar D, Thurlow B, Basu K, Jain N, Gomez-Blanco J, Britton RA, Vargas J, Guarné A, Woodson SA, Williamson JR, Ortega J. Razi A, et al. Nucleic Acids Res. 2019 Sep 5;47(15):8301-8317. doi: 10.1093/nar/gkz571. Nucleic Acids Res. 2019. PMID: 31265110 Free PMC article.
Assembly factors provide speed and directionality to the maturation process of the 30S subunit in bacteria. ...This work establishes Era's role in ribosome assembly and suggests new roles in maintaining ribosome homeostasis....
Assembly factors provide speed and directionality to the maturation process of the 30S subunit in bacteria. ...This work estab
764 results