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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1949 1
1951 1
1952 1
1953 2
1955 6
1956 6
1957 2
1958 4
1959 4
1960 21
1961 53
1962 89
1963 140
1964 380
1965 452
1966 636
1967 792
1968 1080
1969 1262
1970 1336
1971 1747
1972 1891
1973 1948
1974 1945
1975 1848
1976 1639
1977 1563
1978 1480
1979 1598
1980 1397
1981 1324
1982 1329
1983 1266
1984 1306
1985 1195
1986 1169
1987 1219
1988 1317
1989 1476
1990 1568
1991 1659
1992 1764
1993 1936
1994 2067
1995 2302
1996 2355
1997 2559
1998 2703
1999 3037
2000 3490
2001 3595
2002 3918
2003 4123
2004 4704
2005 5281
2006 5598
2007 6180
2008 6539
2009 7373
2010 7743
2011 8226
2012 8783
2013 9534
2014 10045
2015 10232
2016 10510
2017 9767
2018 9905
2019 10329
2020 11450
2021 11675
2022 11257
2023 10066
2024 4816

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Search Results

228,087 results

Results by year

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Page 1
Ribosomes and translation.
Green R, Noller HF. Green R, et al. Annu Rev Biochem. 1997;66:679-716. doi: 10.1146/annurev.biochem.66.1.679. Annu Rev Biochem. 1997. PMID: 9242921 Review.
The ribosome is a large multifunctional complex composed of both RNA and proteins. ...Accumulating evidence suggests that the ribosomal RNAs play central roles in the critical ribosomal functions of tRNA selection and binding, translocation, and peptidyl tran …
The ribosome is a large multifunctional complex composed of both RNA and proteins. ...Accumulating evidence suggests that the ribo
The space between notes: emerging roles for translationally silent ribosomes.
Smith PR, Pandit SC, Loerch S, Campbell ZT. Smith PR, et al. Trends Biochem Sci. 2022 Jun;47(6):477-491. doi: 10.1016/j.tibs.2022.02.003. Epub 2022 Mar 1. Trends Biochem Sci. 2022. PMID: 35246374 Free PMC article. Review.
Vacant ribosomes may provide a means to exclude ribosomes from translation while also shielding them from degradation, and the variable identity of factors that occlude ribosomes may impart distinct functionality. We propose that regulated changes in the bala …
Vacant ribosomes may provide a means to exclude ribosomes from translation while also shielding them from degradation, and the …
Engineered Ribosomes for Basic Science and Synthetic Biology.
d'Aquino AE, Kim DS, Jewett MC. d'Aquino AE, et al. Annu Rev Chem Biomol Eng. 2018 Jun 7;9:311-340. doi: 10.1146/annurev-chembioeng-060817-084129. Epub 2018 Mar 28. Annu Rev Chem Biomol Eng. 2018. PMID: 29589973 Review.
Despite these efforts, the potential for harnessing the translation apparatus to manufacture bio-based products beyond natural limits remains underexploited, and fundamental constraints on the chemistry that the ribosome's RNA-based active site can carry out are unk …
Despite these efforts, the potential for harnessing the translation apparatus to manufacture bio-based products beyond natural limits remain …
Nascent ribosomes.
Warner JR. Warner JR. Cell. 2001 Oct 19;107(2):133-6. doi: 10.1016/s0092-8674(01)00531-1. Cell. 2001. PMID: 11672521 Free article. Review.
The conversion of a ribosomal RNA transcript to a cytoplasmic ribosome requires hundreds of accessory RNA and protein factors. Two papers published recently in Molecular Cell provide first looks at the association of these processing factors with the intermediates i …
The conversion of a ribosomal RNA transcript to a cytoplasmic ribosome requires hundreds of accessory RNA and protein factors. …
Discovery of Mitochondrial Ribosomes.
O'Brien TW. O'Brien TW. Methods Mol Biol. 2023;2661:3-5. doi: 10.1007/978-1-0716-3171-3_1. Methods Mol Biol. 2023. PMID: 37166628
The Impact of Oxidative Stress on Ribosomes: From Injury to Regulation.
Shcherbik N, Pestov DG. Shcherbik N, et al. Cells. 2019 Nov 2;8(11):1379. doi: 10.3390/cells8111379. Cells. 2019. PMID: 31684095 Free PMC article. Review.
Both ribosomal RNA and ribosomal proteins can be chemically modified by reactive oxygen species, which may alter the ribosome's functions or cause a complete loss of functionality. ...However, remarkably little is known about the biological consequence …
Both ribosomal RNA and ribosomal proteins can be chemically modified by reactive oxygen species, which may alter the riboso
Ribosome biogenesis in cancer: new players and therapeutic avenues.
Pelletier J, Thomas G, Volarević S. Pelletier J, et al. Nat Rev Cancer. 2018 Jan;18(1):51-63. doi: 10.1038/nrc.2017.104. Epub 2017 Dec 1. Nat Rev Cancer. 2018. PMID: 29192214 Review.
The ribosome is a complex molecular machine composed of numerous distinct proteins and nucleic acids and is responsible for protein synthesis in every living cell. ...Although causal associations between inherited mutations affecting ribosome biogenesis and elevated …
The ribosome is a complex molecular machine composed of numerous distinct proteins and nucleic acids and is responsible for protein s …
Pre-ribosomes on the road from the nucleolus to the cytoplasm.
Tschochner H, Hurt E. Tschochner H, et al. Trends Cell Biol. 2003 May;13(5):255-63. doi: 10.1016/s0962-8924(03)00054-0. Trends Cell Biol. 2003. PMID: 12742169 Review.
Ribosome formation is a highly dynamic and coordinated multistep process, which requires synthesis, processing and modification of pre-rRNAs, assembly with ribosomal proteins and transient interaction of numerous non-ribosomal factors with the evolving pre-
Ribosome formation is a highly dynamic and coordinated multistep process, which requires synthesis, processing and modification of pr
Chaperone-directed ribosome repair after oxidative damage.
Yang YM, Jung Y, Abegg D, Adibekian A, Carroll KS, Karbstein K. Yang YM, et al. Mol Cell. 2023 May 4;83(9):1527-1537.e5. doi: 10.1016/j.molcel.2023.03.030. Epub 2023 Apr 21. Mol Cell. 2023. PMID: 37086725 Free PMC article.
Because of the central role ribosomes play for protein translation and ribosome-mediated mRNA and protein quality control (RQC), the ribosome pool is surveyed and dysfunctional ribosomes degraded both during assembly, as well as the functional cycle. . …
Because of the central role ribosomes play for protein translation and ribosome-mediated mRNA and protein quality control (RQC …
When ribosomes go bad: diseases of ribosome biogenesis.
Freed EF, Bleichert F, Dutca LM, Baserga SJ. Freed EF, et al. Mol Biosyst. 2010 Mar;6(3):481-93. doi: 10.1039/b919670f. Epub 2010 Jan 11. Mol Biosyst. 2010. PMID: 20174677 Free PMC article. Review.
Ribosomes are vital for cell growth and survival. Until recently, it was believed that mutations in ribosomes or ribosome biogenesis factors would be lethal, due to the essential nature of these complexes. However, in the last few decades, a number of disease
Ribosomes are vital for cell growth and survival. Until recently, it was believed that mutations in ribosomes or ribosome
228,087 results
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