Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1984 1
1987 1
1988 3
1989 5
1991 2
1992 1
1993 2
1994 1
1995 4
1996 1
1997 1
1998 1
1999 1
2000 2
2001 2
2002 1
2004 4
2005 1
2006 2
2008 2
2009 2
2015 1
2016 1
2024 1
2026 0

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

42 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Rilmenidine sympatholytic activity preserves mental stress, orthostatic sympathetic responses and adrenaline secretion.
Esler M, Lux A, Jennings G, Hastings J, Socratous F, Lambert G. Esler M, et al. J Hypertens. 2004 Aug;22(8):1529-34. doi: 10.1097/01.hjh.0000125453.28861.b8. J Hypertens. 2004. PMID: 15257176 Clinical Trial.
OBJECTIVES: To study the sympatholytic and blood pressure-lowering activity of the imidazoline binding agent rilmenidine at rest and during reflex sympathetic activation. DESIGN AND METHODS: We used a randomized, double-blind, 6-week cross-over study, with a 1-week placebo …
OBJECTIVES: To study the sympatholytic and blood pressure-lowering activity of the imidazoline binding agent rilmenidine at rest and …
Rilmenidine in the hypertensive type-2 diabetic: a controlled pilot study versus captopril.
Bauduceau B, Mayaudon H, Dupuy O. Bauduceau B, et al. J Cardiovasc Risk. 2000 Feb;7(1):57-61. doi: 10.1177/204748730000700110. J Cardiovasc Risk. 2000. PMID: 10785875 Clinical Trial.
BACKGROUND: Rilmenidine is an innovative antihypertensive agent that binds specifically to I1 imidazoline receptors. ...CONCLUSION: Rilmenidine exerts similar antihypertensive effects to those of captopril on the hypertensive with type-2 diabetes. ...
BACKGROUND: Rilmenidine is an innovative antihypertensive agent that binds specifically to I1 imidazoline receptors. ...CONCLUSION: …
Dose and concentration-effect relations for rilmenidine.
Dollery CT, Davies DS, Duchier J, Pannier B, Safar ME. Dollery CT, et al. Am J Cardiol. 1988 Feb 24;61(7):60D-66D. Am J Cardiol. 1988. PMID: 2894161 Clinical Trial.
The dose-effect and concentration-effect relations of rilmenidine, a new alpha 2 agonist, were evaluated for the hemodynamic and side-effect responses to single oral doses. ...Dry mouth was assessed by measuring the salivary flow (study I) or by visual analog scale (study …
The dose-effect and concentration-effect relations of rilmenidine, a new alpha 2 agonist, were evaluated for the hemodynamic and side …
[Rilmenidine in rosacea: a double-blind study versus placebo].
Grosshans E, Michel C, Arcade B, Cribier B. Grosshans E, et al. Ann Dermatol Venereol. 1997;124(10):687-91. Ann Dermatol Venereol. 1997. PMID: 9740864 Clinical Trial. French.
The purpose of this study was to evaluate the efficacy of rilmenidine 1 mg/d in the treatment of rosacea. PATIENTS AND METHODS: A total of 41 patients suffering from typical rosacea were selected in this randomised double blind study rilmenidine versus placebo. ...R …
The purpose of this study was to evaluate the efficacy of rilmenidine 1 mg/d in the treatment of rosacea. PATIENTS AND METHODS: A tot …
The effects of rilmenidine and atenolol on mental stress, dynamic exercise and autonomic function in mild to moderate hypertension.
Panfilov V, Morris AD, Donnelly R, Scemama M, Reid JL. Panfilov V, et al. Br J Clin Pharmacol. 1995 Dec;40(6):563-9. doi: 10.1111/j.1365-2125.1995.tb05801.x. Br J Clin Pharmacol. 1995. PMID: 8703663 Free PMC article. Clinical Trial.
During the mental arithmetic test, BP and heart rate (HR) responses were similar for rilmenidine and atenolol. 4. During bicycle exercise, the increase in HR was significantly greater after rilmenidine (+50 vs 41 beats min-1, P = 0.04). ...The standing to lying rati …
During the mental arithmetic test, BP and heart rate (HR) responses were similar for rilmenidine and atenolol. 4. During bicycle exer …
Efficacy and safety of rilmenidine in elderly patients--comparison with hydrochlorothiazide. The Belgian Multicentre Study Group.
Pelemans W, Verhaeghe J, Creytens G, Coupez G, Van Dessel A, Opsomer M, Corcoran C. Pelemans W, et al. Am J Cardiol. 1994 Dec 22;74(13):51A-57A. doi: 10.1016/0002-9149(94)90042-6. Am J Cardiol. 1994. PMID: 7998586 Clinical Trial.
The aim of this trial was to study the treatment of hypertension in the elderly, comparing a new oxazoline antihypertensive agent, rilmenidine, with the diuretic hydrochlorothiazide (HCZ). After 2 weeks on placebo, 88 elderly patients (mean age 75 years; 65 women), corresp …
The aim of this trial was to study the treatment of hypertension in the elderly, comparing a new oxazoline antihypertensive agent, rilmen …
Bioequivalence evaluation of rilmenidine in healthy volunteers.
Groenewoud G, Potgieter L, Meyer B. Groenewoud G, et al. Arzneimittelforschung. 2009;59(5):233-7. doi: 10.1055/s-0031-1296390. Arzneimittelforschung. 2009. PMID: 19537523 Clinical Trial.
In each treatment phase subjects received a single dose of 1.544 mg rilmenidine dihydrogen phosphate (CAS 85409-38-7), equivalent to 1 mg rilmenidine (CAS 54187-04-1). ...The geometric mean C(max) of rilmenidine for the reference and test products was 3.73 an …
In each treatment phase subjects received a single dose of 1.544 mg rilmenidine dihydrogen phosphate (CAS 85409-38-7), equivalent to …
Haemodynamic and metabolic effects of rilmenidine in hypertensive patients with metabolic syndrome X. A double-blind parallel study versus amlodipine.
De Luca N, Izzo R, Fontana D, Iovino G, Argenziano L, Vecchione C, Trimarco B. De Luca N, et al. J Hypertens. 2000 Oct;18(10):1515-22. doi: 10.1097/00004872-200018100-00021. J Hypertens. 2000. PMID: 11057441 Clinical Trial.
OBJECTIVE: To compare the effects of rilmenidine with those of amlodipine on blood pressure, glucose metabolism, plasma lipid concentration and fibrinolysis parameters. ...Plasminogen activator inhibitor type 1 (PAI-1) antigen and PAI-1 activity were only decreased in the …
OBJECTIVE: To compare the effects of rilmenidine with those of amlodipine on blood pressure, glucose metabolism, plasma lipid concent …
Comparison of rilmenidine and lisinopril on ambulatory blood pressure and plasma lipid and glucose levels in hypertensive women with metabolic syndrome.
Anichkov DA, Shostak NA, Schastnaya OV. Anichkov DA, et al. Curr Med Res Opin. 2005 Jan;21(1):113-9. doi: 10.1185/030079904x20277. Curr Med Res Opin. 2005. PMID: 15881482 Clinical Trial.
Rilmenidine significantly increased HDL cholesterol and decreased fasting glucose levels (p = 0.009 and p = 0.012, respectively). ...Rilmenidine compared with lisinopril significantly reduces ambulatory HR. In this study, rilmenidine and lisinopril demonstrat …
Rilmenidine significantly increased HDL cholesterol and decreased fasting glucose levels (p = 0.009 and p = 0.012, respectively). ... …
Antihypertensive efficacy and acceptability of rilmenidine in elderly hypertensive patients.
Galley P, Manciet G, Hessel JL, Michel JP. Galley P, et al. Am J Cardiol. 1988 Feb 24;61(7):86D-90D. doi: 10.1016/0002-9149(88)90472-9. Am J Cardiol. 1988. PMID: 2894166 Clinical Trial.
Elderly hypertensive patients (older than 70 years, with a diastolic blood pressure [BP] between 95 and 114 mm Hg) were entered into a study after a 2-week wash-out period and randomized to 2 parallel groups: rilmenidine (n = 28) and methyldopa (n = 30). The initial dose ( …
Elderly hypertensive patients (older than 70 years, with a diastolic blood pressure [BP] between 95 and 114 mm Hg) were entered into a study …
42 results