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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1994 9
1995 6
1996 23
1997 22
1998 19
1999 26
2000 29
2001 24
2002 32
2003 19
2004 27
2005 22
2006 24
2007 27
2008 29
2009 27
2010 32
2011 36
2012 42
2013 45
2014 34
2015 43
2016 51
2017 59
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2025 80
2026 33

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1,084 results

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Page 1
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Miller RG, Mitchell JD, Moore DH. Miller RG, et al. Cochrane Database Syst Rev. 2012 Mar 14;2012(3):CD001447. doi: 10.1002/14651858.CD001447.pub3. Cochrane Database Syst Rev. 2012. PMID: 22419278 Free PMC article.
BACKGROUND: Riluzole is approved for the treatment of amyotrophic lateral sclerosis in most countries. ...A three-fold increase in serum alanine transferase was more frequent in riluzole-treated patients than controls (mean difference 2.62, 95% …
BACKGROUND: Riluzole is approved for the treatment of amyotrophic lateral sclerosis in most countries. ...A thre …
Riluzole and edaravone: A tale of two amyotrophic lateral sclerosis drugs.
Jaiswal MK. Jaiswal MK. Med Res Rev. 2019 Mar;39(2):733-748. doi: 10.1002/med.21528. Epub 2018 Aug 12. Med Res Rev. 2019. PMID: 30101496 Review.
Over the past decades, a multitude of experimental drugs have been shown to delay disease progression in preclinical animal models of amyotrophic lateral sclerosis (ALS) but failed to show efficacy in human clinical trials or are still waiting for approval un …
Over the past decades, a multitude of experimental drugs have been shown to delay disease progression in preclinical animal models of amy …
Riluzole for the treatment of amyotrophic lateral sclerosis.
Saitoh Y, Takahashi Y. Saitoh Y, et al. Neurodegener Dis Manag. 2020 Dec;10(6):343-355. doi: 10.2217/nmt-2020-0033. Epub 2020 Aug 27. Neurodegener Dis Manag. 2020. PMID: 32847483
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by the death of motor neurons. ...Riluzole was approved by the US FDA in 1995 as the first drug to treat ALS. Although riluzole is generally safe and well tole …
Amyotrophic lateral sclerosis (ALS) is a progressive neurodegenerative disease caused by the death of motor neurons. .. …
A controlled trial of riluzole in amyotrophic lateral sclerosis. ALS/Riluzole Study Group.
Bensimon G, Lacomblez L, Meininger V. Bensimon G, et al. N Engl J Med. 1994 Mar 3;330(9):585-91. doi: 10.1056/NEJM199403033300901. N Engl J Med. 1994. PMID: 8302340 Free article. Clinical Trial.
BACKGROUND: Amyotrophic lateral sclerosis is a progressive motor neuron disease for which there is no adequate treatment. ...METHODS: To evaluate the efficacy and safety of the antiglutamate agent riluzole, we conducted a prospective, double-blind, pla …
BACKGROUND: Amyotrophic lateral sclerosis is a progressive motor neuron disease for which there is no adequate treatmen …
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Miller RG, Mitchell JD, Lyon M, Moore DH. Miller RG, et al. Cochrane Database Syst Rev. 2002;(2):CD001447. doi: 10.1002/14651858.CD001447. Cochrane Database Syst Rev. 2002. Update in: Cochrane Database Syst Rev. 2007 Jan 24;(1):CD001447. doi: 10.1002/14651858.CD001447.pub2. PMID: 12076411 Updated.
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis in many countries but not all. ...REVIEWER'S CONCLUSIONS: Riluzole 100 mg daily is reasonably safe and probably prolongs survival by about two mo …
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis in many coun …
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Miller RG, Mitchell JD, Lyon M, Moore DH. Miller RG, et al. Cochrane Database Syst Rev. 2007 Jan 24;(1):CD001447. doi: 10.1002/14651858.CD001447.pub2. Cochrane Database Syst Rev. 2007. Update in: Cochrane Database Syst Rev. 2012 Mar 14;(3):CD001447. doi: 10.1002/14651858.CD001447.pub3. PMID: 17253460 Updated.
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis in most countries. ...TYPES OF PARTICIPANTS: adults with a diagnosis of amyotrophic lateral sclerosis. Types of interventions: trea …
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis in most coun …
Treatment continuity of amyotrophic lateral sclerosis with available riluzole formulations: state of the art and current challenges in a 'real-world' setting.
Corcia P, Guy N, Pradat PF, Soriani MH, Verschueren A, Couratier P. Corcia P, et al. Amyotroph Lateral Scler Frontotemporal Degener. 2025 Feb;26(1-2):15-21. doi: 10.1080/21678421.2024.2375330. Epub 2024 Jul 7. Amyotroph Lateral Scler Frontotemporal Degener. 2025. PMID: 38973130 Free article. Review.
Amyotrophic lateral sclerosis (ALS) is a rare multisystem neurodegenerative disease leading to death due to respiratory failure. ...Tablet crushing is associated with a loss of drug intake and a risk of powder aspiration, which jeopardizes the benefits of …
Amyotrophic lateral sclerosis (ALS) is a rare multisystem neurodegenerative disease leading to death due to respiratory …
Amyotrophic lateral sclerosis.
Rowland LP. Rowland LP. Curr Opin Neurol. 1994 Aug;7(4):310-5. doi: 10.1097/00019052-199408000-00006. Curr Opin Neurol. 1994. PMID: 7952238 Review.
Therapeutic trials for amyotrophic lateral sclerosis have attracted much attention, but no drug tested has been effective yet. ...In striking contrast to the negative results of all of the other drug trials, riluzole (a glutamate antagonist) was said t …
Therapeutic trials for amyotrophic lateral sclerosis have attracted much attention, but no drug tested has been effecti …
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Miller RG, Mitchell JD, Moore DH. Miller RG, et al. Cochrane Database Syst Rev. 2001;(4):CD001447. doi: 10.1002/14651858.CD001447. Cochrane Database Syst Rev. 2001. Update in: Cochrane Database Syst Rev. 2002;(2):CD001447. doi: 10.1002/14651858.CD001447. PMID: 11687111 Updated.
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis (ALS) in some countries but not others. ...There were significant differences between the riluzole and placebo groups of both trials, in terms of …
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis (ALS) in som …
Riluzole for amyotrophic lateral sclerosis (ALS)/motor neuron disease (MND).
Miller RG, Mitchell JD, Moore DH. Miller RG, et al. Cochrane Database Syst Rev. 2000;(2):CD001447. doi: 10.1002/14651858.CD001447. Cochrane Database Syst Rev. 2000. Update in: Cochrane Database Syst Rev. 2001;(4):CD001447. doi: 10.1002/14651858.CD001447. PMID: 10796796 Updated.
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis (ALS) in some countries but not others. ...There were significant differences between the riluzole and placebo groups of both trials, in terms of …
BACKGROUND: Riluzole has been approved for treatment of patients with amyotrophic lateral sclerosis (ALS) in som …
1,084 results