Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

My NCBI Filters
Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 2
1982 2
1985 1
1986 2
1987 4
1988 1
1989 1
1990 1
1991 2
1995 1
1998 3
1999 2
2000 1
2001 1
2003 2
2005 1
2006 2
2008 1
2011 2
2012 4
2014 1
2023 0
Text availability
Article attribute
Article type
Publication date

Search Results

35 results
Results by year
Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
Amantadine and rimantadine for influenza A in children and the elderly.
Alves Galvão MG, Rocha Crispino Santos MA, Alves da Cunha AJ. Alves Galvão MG, et al. Cochrane Database Syst Rev. 2014 Nov 21;2014(11):CD002745. doi: 10.1002/14651858.CD002745.pub4. Cochrane Database Syst Rev. 2014. PMID: 25415374 Free PMC article. Review.
SELECTION CRITERIA: Randomised controlled trials (RCTs) or quasi-RCTs comparing amantadine and/or rimantadine with no intervention, placebo, other antivirals or different doses or schedules of amantadine or rimantadine in children and the elderly with influenza A. . …
SELECTION CRITERIA: Randomised controlled trials (RCTs) or quasi-RCTs comparing amantadine and/or rimantadine with no intervention, p …
Amantadine and rimantadine for influenza A in adults.
Jefferson T, Demicheli V, Di Pietrantonj C, Rivetti D. Jefferson T, et al. Cochrane Database Syst Rev. 2006 Apr 19;2006(2):CD001169. doi: 10.1002/14651858.CD001169.pub3. Cochrane Database Syst Rev. 2006. PMID: 16625539 Free PMC article. Review.
SELECTION CRITERIA: Randomised and quasi-randomised studies comparing amantadine and/or rimantadine with placebo, control medication or no intervention, or comparing doses or schedules of amantadine and/or rimantadine in healthy adults. ...Both amantadine and rim
SELECTION CRITERIA: Randomised and quasi-randomised studies comparing amantadine and/or rimantadine with placebo, control medication …
A case for rimantadine to be marketed in Canada for prophylaxis of influenza A virus infection.
Marra F, Marra CA, Stiver HG. Marra F, et al. Can Respir J. 2003 Oct;10(7):381-8. doi: 10.1155/2003/453183. Can Respir J. 2003. PMID: 14571290 Free article. Review.
PURPOSE: To evaluate the efficacy and safety of amantadine and rimantadine, the first generation antivirals, for the prophylaxis of influenza virus. ...Discrepancies in data extraction among the investigators were solved by consensus. Nine prophylaxis studies of amantadine …
PURPOSE: To evaluate the efficacy and safety of amantadine and rimantadine, the first generation antivirals, for the prophylaxis of i …
Amantadine and rimantadine for influenza A in children and the elderly.
Alves Galvão MG, Rocha Crispino Santos MA, Alves da Cunha AJ. Alves Galvão MG, et al. Cochrane Database Syst Rev. 2008 Jan 23;(1):CD002745. doi: 10.1002/14651858.CD002745.pub2. Cochrane Database Syst Rev. 2008. PMID: 18254006 Updated. Review.
BACKGROUND: Although amantadine (AMT) and rimantadine (RMT) are used to relieve or treat influenza A symptoms in healthy adults, little is known about the effectiveness and safety of these antivirals in preventing and treating influenza A in children and the elderly. ...
BACKGROUND: Although amantadine (AMT) and rimantadine (RMT) are used to relieve or treat influenza A symptoms in healthy adults, litt …
Amantadine and rimantadine for influenza A in children and the elderly.
Alves Galvão MG, Rocha Crispino Santos MA, Alves da Cunha AJ. Alves Galvão MG, et al. Cochrane Database Syst Rev. 2012 Jan 18;1:CD002745. doi: 10.1002/14651858.CD002745.pub3. Cochrane Database Syst Rev. 2012. PMID: 22258950 Updated. Review.
BACKGROUND: The effectiveness and safety of amantadine (AMT) and rimantadine (RMT) for preventing and treating influenza A in adults has been systematically reviewed. ...
BACKGROUND: The effectiveness and safety of amantadine (AMT) and rimantadine (RMT) for preventing and treating influenza A in adults …
Effect of rimantadine treatment on clinical manifestations and otologic complications in adults experimentally infected with influenza A (H1N1) virus.
Doyle WJ, Skoner DP, Alper CM, Allen G, Moody SA, Seroky JT, Hayden FG. Doyle WJ, et al. J Infect Dis. 1998 May;177(5):1260-5. doi: 10.1086/515294. J Infect Dis. 1998. PMID: 9593010 Clinical Trial.
Susceptible adults (n = 105) were enrolled into a randomized double-blind study of rimantadine treatment of experimental influenza A infection. Subjects were cloistered for 8 days and challenged with a rimantadine-sensitive strain of influenza A H1N1 virus at the en …
Susceptible adults (n = 105) were enrolled into a randomized double-blind study of rimantadine treatment of experimental influenza A …
Rimantadine pharmacokinetics after single and multiple doses.
Wills RJ, Farolino DA, Choma N, Keigher N. Wills RJ, et al. Antimicrob Agents Chemother. 1987 May;31(5):826-8. doi: 10.1128/AAC.31.5.826. Antimicrob Agents Chemother. 1987. PMID: 3606083 Free PMC article. Clinical Trial.
Twenty-four healthy adult male volunteers were randomly assigned to one of two rimantadine regimens. The 12 volunteers assigned to regimen 1 orally received a single 100-mg rimantadine tablet followed 5 days later by 100 mg of rimantadine twice a day for 10 d …
Twenty-four healthy adult male volunteers were randomly assigned to one of two rimantadine regimens. The 12 volunteers assigned to re …
Safety and efficacy of long-term use of rimantadine for prophylaxis of type A influenza in nursing homes.
Monto AS, Ohmit SE, Hornbuckle K, Pearce CL. Monto AS, et al. Antimicrob Agents Chemother. 1995 Oct;39(10):2224-8. doi: 10.1128/AAC.39.10.2224. Antimicrob Agents Chemother. 1995. PMID: 8619572 Free PMC article. Clinical Trial.
The safety and efficacy of rimantadine for long-term prophylaxis of influenza A (H3N2) infection were evaluated among elderly residents in 10 nursing homes. ...The results suggest the relative safety and clinical efficacy of using rimantadine for influenza prophylax …
The safety and efficacy of rimantadine for long-term prophylaxis of influenza A (H3N2) infection were evaluated among elderly residen …
A controlled trial of amantadine and rimantadine in the prophylaxis of influenza A infection.
Dolin R, Reichman RC, Madore HP, Maynard R, Linton PN, Webber-Jones J. Dolin R, et al. N Engl J Med. 1982 Sep 2;307(10):580-4. doi: 10.1056/NEJM198209023071002. N Engl J Med. 1982. PMID: 7050702 Clinical Trial.
These findings represent efficacy rates of 85 per cent for rimantadine and 91 per cent for amantadine, as compared with placebo. ...On the basis of this study, rimantadine appears to be the drug of choice for the prophylaxis of influenza A....
These findings represent efficacy rates of 85 per cent for rimantadine and 91 per cent for amantadine, as compared with placebo. ...O …
Comparative single-dose pharmacokinetics of amantadine hydrochloride and rimantadine hydrochloride in young and elderly adults.
Hayden FG, Minocha A, Spyker DA, Hoffman HE. Hayden FG, et al. Antimicrob Agents Chemother. 1985 Aug;28(2):216-21. doi: 10.1128/AAC.28.2.216. Antimicrob Agents Chemother. 1985. PMID: 3834831 Free PMC article. Clinical Trial.
No significant age-related differences were noted for rimantadine. Urinary excretion (0 to 24 h) of rimantadine and its hydroxylated metabolites averaged 19% of the administered dose. The maximum nasal mucus drug concentration was similar for both drugs (0.42 +/- 0. …
No significant age-related differences were noted for rimantadine. Urinary excretion (0 to 24 h) of rimantadine and its hydrox …
35 results