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1993 4
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731 results

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Page 1
Risk-reducing mastectomy.
Edlich RF, Winters KL, Faulkner BC, Lin KY. Edlich RF, et al. J Long Term Eff Med Implants. 2006;16(4):301-14. doi: 10.1615/jlongtermeffmedimplants.v16.i4.40. J Long Term Eff Med Implants. 2006. PMID: 17073572 Review.
The surgical technique involves several operations to include the risk-reducing mastectomy as well as breast reconstructive procedures. Skin-sparing mastectomy represents a new surgical approach that allows a mastectomy, whereas preserving the n …
The surgical technique involves several operations to include the risk-reducing mastectomy as well as breast reconstruc …
Risk-reducing mastectomy.
Chiesa F, Sacchini VS. Chiesa F, et al. Minerva Ginecol. 2016 Oct;68(5):544-7. Epub 2016 Jan 19. Minerva Ginecol. 2016. PMID: 26785281 Free PMC article. Review.
Mastectomy rates have significantly increased over the last decades, likely due to the rising trend of risk-reducing mastectomies (RRM) in the treatment and prevention of breast cancer. Growing evidence suggests that aggressive risk-reducing …
Mastectomy rates have significantly increased over the last decades, likely due to the rising trend of risk-reducing …
Risk-Reducing Mastectomy.
Jatoi I, Kemp Z. Jatoi I, et al. JAMA. 2021 May 4;325(17):1781-1782. doi: 10.1001/jama.2020.22414. JAMA. 2021. PMID: 33944884 No abstract available.
Risk-Reducing Bilateral Mastectomy and Mortality in Carriers of BRCA1 and BRCA2 Variants: A Systematic Review and Meta-Analysis.
O'Reilly C, McGarry JL, Zaborowski AM, Davey MG, Evoy D, Rothwell J, McCartan D, Rutherford CL, Boland MR, Prichard RS. O'Reilly C, et al. JAMA Surg. 2026 Mar 1;161(3):260-267. doi: 10.1001/jamasurg.2025.5929. JAMA Surg. 2026. PMID: 41499127
IMPORTANCE: Risk-reducing bilateral mastectomy reduces the incidence of breast cancer in female carriers of the BRCA pathogenic variants, but its association with mortality remains uncertain. OBJECTIVE: To evaluate the association between risk-reduc …
IMPORTANCE: Risk-reducing bilateral mastectomy reduces the incidence of breast cancer in female carriers of the BRCA pa …
Risk-reducing mastectomy in healthy women with BRCA mutation: a narrative review.
Cipolla C, Scandurra G, Sambataro D, Mesi C, Greco M, D'Agati E, Gebbia V, Valerio MR. Cipolla C, et al. Expert Rev Anticancer Ther. 2025 Jul;25(7):797-807. doi: 10.1080/14737140.2025.2513451. Epub 2025 Jun 2. Expert Rev Anticancer Ther. 2025. PMID: 40432480 Review.
INTRODUCTION: Breast cancer (BC) prevention in BRCA1/2 mutation carriers remains a significant clinical challenge. Risk-reducing mastectomy (RRM) is the most effective preventive option, lowering BC incidence by over 90%. ...Large cohort studies and systemati …
INTRODUCTION: Breast cancer (BC) prevention in BRCA1/2 mutation carriers remains a significant clinical challenge. Risk-reducing …
Risk-reducing mastectomy and breast cancer mortality in women with a BRCA1 or BRCA2 pathogenic variant: an international analysis.
Metcalfe K, Huzarski T, Gronwald J, Kotsopoulos J, Kim R, Moller P, Pal T, Aeilts A, Eisen A, Karlan B, Bordeleau L, Tung N, Olopade O, Zakalik D, Singer CF, Foulkes W, Couch F, Neuhausen SL, Eng C, Sun P, Lubinski J, Narod SA; Hereditary Breast Cancer Clinical Study Group. Metcalfe K, et al. Br J Cancer. 2024 Feb;130(2):269-274. doi: 10.1038/s41416-023-02503-8. Epub 2023 Nov 29. Br J Cancer. 2024. PMID: 38030749 Free PMC article.
BACKGROUND: Risk-reducing mastectomy (RRM) is offered to women with a BRCA1 or BRCA2 pathogenic variant, however, there are limited data on the impact on breast cancer mortality. ...
BACKGROUND: Risk-reducing mastectomy (RRM) is offered to women with a BRCA1 or BRCA2 pathogenic variant, however, there …
Nipple Sparing Mastectomy as a Risk-Reducing Procedure for BRCA-Mutated Patients.
Rocco N, Montagna G, Criscitiello C, Nava MB, Privitera F, Taher W, Gloria A, Catanuto G. Rocco N, et al. Genes (Basel). 2021 Feb 10;12(2):253. doi: 10.3390/genes12020253. Genes (Basel). 2021. PMID: 33578759 Free PMC article. Review.
Growing numbers of asymptomatic women who become aware of carrying a breast cancer gene mutation (BRCA) mutation are choosing to undergo risk-reducing bilateral mastectomies with immediate breast reconstruction. We reviewed the literature with the aim of asse …
Growing numbers of asymptomatic women who become aware of carrying a breast cancer gene mutation (BRCA) mutation are choosing to undergo …
Association between risk-reducing surgeries and survival in young BRCA carriers with breast cancer: an international cohort study.
Blondeaux E, Sonnenblick A, Agostinetto E, Bas R, Kim HJ, Franzoi MA, Bernstein-Molho R, Linn S, Kwong A, Pogoda K, Balmana J, Smeets A, Bajpai J, Moore HCF, Partridge AH, Phillips KA, Toss A, Rousset-Jablonski C, Peccatori FA, Renaud T, Ferrari A, Paluch-Shimon S, Mando P, Lee JE, Fruscio R, Cui W, Wong SM, Vernieri C, Ruddy KJ, Dieci MV, Matikas A, Rozenblit M, Guven DC, Lee M, Villarreal-Garza C, Hwang SE, De Marchis L, Puglisi F, Kemp Z, Meireles PA, Parokonnaya A, Werutsky G, Okano M, Azim HA Jr, Mati K, Rosenberg S, Gelber R, Boni L, Lambertini M. Blondeaux E, et al. Lancet Oncol. 2025 Jun;26(6):759-770. doi: 10.1016/S1470-2045(25)00152-4. Epub 2025 May 8. Lancet Oncol. 2025. PMID: 40347973
BACKGROUND: Little evidence exists on the effect of risk-reducing surgeries in young BRCA carriers with a previous history of breast cancer. We investigated the association between risk-reducing mastectomy (RRM) or risk-reducing sa …
BACKGROUND: Little evidence exists on the effect of risk-reducing surgeries in young BRCA carriers with a previous history of …
Survival Outcomes With or Without Risk-Reducing Mastectomy in BRCA1 and BRCA2 Pathogenic Variant Carriers.
Gandhi A, Howell SJ, Harkness EF, Woodward E, Lalloo F, Forde C, Harvey J, Highton L, Flaum N, Evans DG. Gandhi A, et al. J Clin Oncol. 2026 Apr;44(10):874-882. doi: 10.1200/JCO-25-00834. Epub 2026 Feb 4. J Clin Oncol. 2026. PMID: 41637687
PURPOSE: Many women carrying pathogenic variants (pvs) of BRCA1 and BRCA2 genes (pvBRCA1/2) elect to undergo bilateral risk-reducing mastectomy (BRRM) in the belief that it will improve their overall survival (OS). ...CONCLUSION: For women electing imaging su …
PURPOSE: Many women carrying pathogenic variants (pvs) of BRCA1 and BRCA2 genes (pvBRCA1/2) elect to undergo bilateral risk-reduci …
Risk-reducing mastectomy in mutation carriers.
Zaborowski AM, Boland MR. Zaborowski AM, et al. Br J Surg. 2024 Oct 1;111(10):znae264. doi: 10.1093/bjs/znae264. Br J Surg. 2024. PMID: 39441657 Free article. No abstract available.
731 results