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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1981 1
1987 2
1988 4
1989 2
1990 5
1991 9
1992 13
1993 6
1994 14
1995 13
1996 9
1997 7
1998 14
1999 5
2000 16
2001 11
2002 6
2003 13
2004 8
2005 27
2006 16
2007 20
2008 23
2009 59
2010 221
2011 464
2012 771
2013 1318
2014 2637
2015 3251
2016 4437
2017 4058
2018 4644
2019 6215
2020 7693
2021 1596
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33,282 results
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Page 1
RNA-seq in Skeletal Biology.
Ayturk U. Ayturk U. Curr Osteoporos Rep. 2019 Aug;17(4):178-185. doi: 10.1007/s11914-019-00517-x. Curr Osteoporos Rep. 2019. PMID: 31093870 Review.
RNA-seq has led to the identification of novel genes and transcription factors involved in skeletal development and disease, through its application in small and large animal models, as well as human tissue and cells. With the availability of advanced techniques suc
RNA-seq has led to the identification of novel genes and transcription factors involved in skeletal development and disease, t
Single-Cell RNA-Seq of the Pancreatic Islets--a Promise Not yet Fulfilled?
Wang YJ, Kaestner KH. Wang YJ, et al. Cell Metab. 2019 Mar 5;29(3):539-544. doi: 10.1016/j.cmet.2018.11.016. Epub 2018 Dec 20. Cell Metab. 2019. PMID: 30581120 Free PMC article. Review.
In the past 3 years, we have seen a flurry of publications on single-cell RNA sequencing (RNA-seq) analyses of pancreatic islets from mouse and human. ...Data generation and analysis are continuously improving single-cell RNA-seq approaches and …
In the past 3 years, we have seen a flurry of publications on single-cell RNA sequencing (RNA-seq) analyses of pancreat …
An RNA-Seq Protocol for Differential Expression Analysis.
Owens NDL, De Domenico E, Gilchrist MJ. Owens NDL, et al. Cold Spring Harb Protoc. 2019 Jun 3;2019(6). doi: 10.1101/pdb.prot098368. Cold Spring Harb Protoc. 2019. PMID: 30952685
Here we consider RNA-Seq, used to measure global gene expression through RNA fragmentation, capture, sequencing, and subsequent computational analysis. ...Here we present a standard RNA-Seq protocol for performing two-state differential gene exp …
Here we consider RNA-Seq, used to measure global gene expression through RNA fragmentation, capture, sequencing, and su …
Evaluation of tools for highly variable gene discovery from single-cell RNA-seq data.
Yip SH, Sham PC, Wang J. Yip SH, et al. Brief Bioinform. 2019 Jul 19;20(4):1583-1589. doi: 10.1093/bib/bby011. Brief Bioinform. 2019. PMID: 29481632 Free PMC article. Review.
However, genes that contribute to cell-to-cell differences are not discoverable with RNA-seq because RNA-seq samples are obtained from a mixture of cells. Single-cell RNA-seq (scRNA-seq) allows the detection of gene expression in e …
However, genes that contribute to cell-to-cell differences are not discoverable with RNA-seq because RNA-seq sam …
Single-nuclei RNA-seq on human retinal tissue provides improved transcriptome profiling.
Liang Q, Dharmat R, Owen L, Shakoor A, Li Y, Kim S, Vitale A, Kim I, Morgan D, Liang S, Wu N, Chen K, DeAngelis MM, Chen R. Liang Q, et al. Nat Commun. 2019 Dec 17;10(1):5743. doi: 10.1038/s41467-019-12917-9. Nat Commun. 2019. PMID: 31848347 Free PMC article.
Here, we report a single-nuclei RNA-seq (snRNA-seq) transcriptomic study on human retinal tissue, which is composed of multiple cell types with distinct functions. ...Furthermore, our dataset shows an improved power for prioritizing genes associated with huma …
Here, we report a single-nuclei RNA-seq (snRNA-seq) transcriptomic study on human retinal tissue, which is composed of …
Single-cell RNA-seq data analysis on the receptor ACE2 expression reveals the potential risk of different human organs vulnerable to 2019-nCoV infection.
Zou X, Chen K, Zou J, Han P, Hao J, Han Z. Zou X, et al. Front Med. 2020 Apr;14(2):185-192. doi: 10.1007/s11684-020-0754-0. Epub 2020 Mar 12. Front Med. 2020. PMID: 32170560 Free PMC article.
To construct a risk map of different human organs, we analyzed the single-cell RNA sequencing (scRNA-seq) datasets derived from major human physiological systems, including the respiratory, cardiovascular, digestive, and urinary systems. Through scRNA-seq dat …
To construct a risk map of different human organs, we analyzed the single-cell RNA sequencing (scRNA-seq) datasets derived fro …
Dissecting intratumoral myeloid cell plasticity by single cell RNA-seq.
Song Q, Hawkins GA, Wudel L, Chou PC, Forbes E, Pullikuth AK, Liu L, Jin G, Craddock L, Topaloglu U, Kucera G, O'Neill S, Levine EA, Sun P, Watabe K, Lu Y, Alexander-Miller MA, Pasche B, Miller LD, Zhang W. Song Q, et al. Cancer Med. 2019 Jun;8(6):3072-3085. doi: 10.1002/cam4.2113. Epub 2019 Apr 29. Cancer Med. 2019. PMID: 31033233 Free PMC article.
However, the in situ dynamics of the transcriptional reprogramming underlying this process are poorly understood. Therefore, we applied single cell RNA-seq (scRNA-seq) to computationally investigate the cellular composition and transcriptional dynamics of tum …
However, the in situ dynamics of the transcriptional reprogramming underlying this process are poorly understood. Therefore, we applied sing …
Phospho-RNA-seq: a modified small RNA-seq method that reveals circulating mRNA and lncRNA fragments as potential biomarkers in human plasma.
Giraldez MD, Spengler RM, Etheridge A, Goicochea AJ, Tuck M, Choi SW, Galas DJ, Tewari M. Giraldez MD, et al. EMBO J. 2019 Jun 3;38(11):e101695. doi: 10.15252/embj.2019101695. Epub 2019 May 3. EMBO J. 2019. PMID: 31053596 Free PMC article.
We report that plasma contains fragmented mRNAs and lncRNAs that are missed by standard small RNA-seq protocols due to lack of 5' phosphate or presence of 3' phosphate. These fragments were revealed using a modified protocol ("phospho-RNA-seq") incorpo …
We report that plasma contains fragmented mRNAs and lncRNAs that are missed by standard small RNA-seq protocols due to lack of …
A systematic evaluation of single cell RNA-seq analysis pipelines.
Vieth B, Parekh S, Ziegenhain C, Enard W, Hellmann I. Vieth B, et al. Nat Commun. 2019 Oct 11;10(1):4667. doi: 10.1038/s41467-019-12266-7. Nat Commun. 2019. PMID: 31604912 Free PMC article.
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and computational pipelines for which best practices have not yet been established. ...Finally, we illustrate the importance of informed choices by …
The recent rapid spread of single cell RNA sequencing (scRNA-seq) methods has created a large variety of experimental and comp …
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