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Anaplerotic treatment of long-chain fat oxidation disorders with triheptanoin: Review of 15 years Experience.
Roe CR, Brunengraber H. Roe CR, et al. Mol Genet Metab. 2015 Dec;116(4):260-8. doi: 10.1016/j.ymgme.2015.10.005. Epub 2015 Oct 24. Mol Genet Metab. 2015. PMID: 26547562 Free PMC article.
BACKGROUND: The treatment of long-chain mitochondrial beta-oxidation disorders (LC-FOD) with a low fat-high carbohydrate diet, a diet rich in medium-even-chain triglycerides (MCT), or a combination of both has been associated with high morbidity …
BACKGROUND: The treatment of long-chain mitochondrial beta-oxidation disorders (LC-FOD) with a low fat-high carb …
Treatment of cardiomyopathy and rhabdomyolysis in long-chain fat oxidation disorders using an anaplerotic odd-chain triglyceride.
Roe CR, Sweetman L, Roe DS, David F, Brunengraber H. Roe CR, et al. J Clin Invest. 2002 Jul;110(2):259-69. doi: 10.1172/JCI15311. J Clin Invest. 2002. PMID: 12122118 Free PMC article.
The current dietary treatment of long-chain fatty acid oxidation defects (high carbohydrate with medium-even-chain triglycerides and reduced amounts of long-chain fats) fails, in many cases, to prevent cardiomyopathy, rhabdomyolysis, and …
The current dietary treatment of long-chain fatty acid oxidation defects (high carbohydrate with medium-even-chain …