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Phase 1/2a clinical trial in ALS with ropinirole, a drug candidate identified by iPSC drug discovery.
Morimoto S, Takahashi S, Ito D, Daté Y, Okada K, Kato C, Nakamura S, Ozawa F, Chyi CM, Nishiyama A, Suzuki N, Fujimori K, Kondo T, Takao M, Hirai M, Kabe Y, Suematsu M, Jinzaki M, Aoki M, Fujiki Y, Sato Y, Suzuki N, Nakahara J; Pooled Resource Open-Access ALS Clinical Trials Consortium; Okano H. Morimoto S, et al. Cell Stem Cell. 2023 Jun 1;30(6):766-780.e9. doi: 10.1016/j.stem.2023.04.017. Cell Stem Cell. 2023. PMID: 37267913 Free article. Clinical Trial.
[Ropinirole Hydrochloride for ALS].
Takahashi S, Morimoto S, Fukushima K, Nakahara J, Okano H. Takahashi S, et al. Brain Nerve. 2019 Nov;71(11):1279-1288. doi: 10.11477/mf.1416201438. Brain Nerve. 2019. PMID: 31722314 Clinical Trial. Japanese.
Influence of the nonergot dopamine agonist piribedil on vigilance in patients With Parkinson Disease and excessive daytime sleepiness (PiViCog-PD): an 11-week randomized comparison trial against pramipexole and ropinirole.
Eggert K, Öhlwein C, Kassubek J, Wolz M, Kupsch A, Ceballos-Baumann A, Ehret R, Polzer U, Klostermann F, Schwarz J, Fuchs G, Jost W, Albert A, Haag A, Hermsen A, Lohmüller K, Kuhn K, Wangemann M, Oertel WH; In Cooperation With the German Competence Network on Parkinson’s Disease. Eggert K, et al. Clin Neuropharmacol. 2014 Jul-Aug;37(4):116-22. doi: 10.1097/WNF.0000000000000041. Clin Neuropharmacol. 2014. PMID: 24992083 Clinical Trial.
15 results