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Page 1
Rosmarinic acid potentiates carnosic acid induced apoptosis in lung fibroblasts.
Bahri S, Mies F, Ben Ali R, Mlika M, Jameleddine S, Mc Entee K, Shlyonsky V. Bahri S, et al. PLoS One. 2017 Sep 6;12(9):e0184368. doi: 10.1371/journal.pone.0184368. eCollection 2017. PLoS One. 2017. PMID: 28877257 Free PMC article.
Pulmonary fibrosis is characterized by over-population and excessive activation of fibroblasts and myofibroblasts disrupting normal lung structure and functioning. Rosemary extract rich in carnosic acid (CA) and rosmarinic acid (RA) was reported …
Pulmonary fibrosis is characterized by over-population and excessive activation of fibroblasts and myofibroblasts disrupting normal lung str …
Effect of rosmarinic acid and carnosic acid on AGEs formation in vitro.
Ou J, Huang J, Wang M, Ou S. Ou J, et al. Food Chem. 2017 Apr 15;221:1057-1061. doi: 10.1016/j.foodchem.2016.11.056. Epub 2016 Nov 11. Food Chem. 2017. PMID: 27979058
This work aimed to investigate the effect of the two main components of rosemary extracts, namely rosmarinic acid (RA) and carnosic acid (CA), on the formation of advanced glycation end-products (AGEs) in vitro. ...
This work aimed to investigate the effect of the two main components of rosemary extracts, namely rosmarinic acid (RA) …
Neuroprotection Comparison of Rosmarinic Acid and Carnosic Acid in Primary Cultures of Cerebellar Granule Neurons.
Taram F, Ignowski E, Duval N, Linseman DA. Taram F, et al. Molecules. 2018 Nov 13;23(11):2956. doi: 10.3390/molecules23112956. Molecules. 2018. PMID: 30428519 Free PMC article.
In the current study, we compared the neuroprotective effects of two polyphenolic compounds, rosmarinic acid and carnosic acid, which are both found at substantial concentrations in the herb rosemary. ...Both polyphenols significantly reduced CG …
In the current study, we compared the neuroprotective effects of two polyphenolic compounds, rosmarinic acid and carnosic …
Effect of botanical extracts containing carnosic acid or rosmarinic acid on learning and memory in SAMP8 mice.
Farr SA, Niehoff ML, Ceddia MA, Herrlinger KA, Lewis BJ, Feng S, Welleford A, Butterfield DA, Morley JE. Farr SA, et al. Physiol Behav. 2016 Oct 15;165:328-38. doi: 10.1016/j.physbeh.2016.08.013. Epub 2016 Aug 12. Physiol Behav. 2016. PMID: 27527000 Free article.
The two rosemary extracts contained carnosic acid (60% or 10% carnosic acid) and one spearmint extract contained 5% rosmarinic acid. ...Protein carbonyls were reduced in the hippocampus after administration of rosemary with …
The two rosemary extracts contained carnosic acid (60% or 10% carnosic acid) and one spearmint extract co …
Inhibitory effects of rosemary extracts, carnosic acid and rosmarinic acid on the growth of various human cancer cell lines.
Yesil-Celiktas O, Sevimli C, Bedir E, Vardar-Sukan F. Yesil-Celiktas O, et al. Plant Foods Hum Nutr. 2010 Jun;65(2):158-63. doi: 10.1007/s11130-010-0166-4. Plant Foods Hum Nutr. 2010. PMID: 20449663
Subsequently, six extracts and the active compounds, carnosic acid, and rosmarinic acid were applied to various human cancer cell lines including NCI-H82 (human, small cell lung, carcinoma), DU-145 (human, prostate, carcinoma), Hep-3B (human, black, li …
Subsequently, six extracts and the active compounds, carnosic acid, and rosmarinic acid were applied to various …
Differential activation of pregnane X receptor by carnosic acid, carnosol, ursolic acid, and rosmarinic acid.
Seow CL, Lau AJ. Seow CL, et al. Pharmacol Res. 2017 Jun;120:23-33. doi: 10.1016/j.phrs.2017.03.007. Epub 2017 Mar 10. Pharmacol Res. 2017. PMID: 28288941
In the present study, we determined whether carnosic acid and other chemicals in rosemary extract (carnosol, ursolic acid, and rosmarinic acid) are PXR activators. As assessed in dual-luciferase reporter gene assays, carnosic ac …
In the present study, we determined whether carnosic acid and other chemicals in rosemary extract (carnosol, ursolic …
Network pharmacology mechanism of Rosmarinus officinalis L.(Rosemary) to improve cell viability and reduces apoptosis in treating Alzheimer's disease.
Zhao J, Li Z, Zhang R, Yu H, Zhang L. Zhao J, et al. BMC Complement Med Ther. 2025 Mar 7;25(1):94. doi: 10.1186/s12906-025-04771-8. BMC Complement Med Ther. 2025. PMID: 40055645 Free PMC article.
Additionally, a main antioxidant compound in rosemary, carnosic acid, also has neuroprotective effects. Eight main antioxidant compounds of rosemary ware collected. Network pharmacology and molecular docking, revealed that rosemary plays …
Additionally, a main antioxidant compound in rosemary, carnosic acid, also has neuroprotective effects. Eight main anti …
Anticancer Effects of Rosemary (Rosmarinus officinalis L.) Extract and Rosemary Extract Polyphenols.
Moore J, Yousef M, Tsiani E. Moore J, et al. Nutrients. 2016 Nov 17;8(11):731. doi: 10.3390/nu8110731. Nutrients. 2016. PMID: 27869665 Free PMC article. Review.
Rosemary extract contains many polyphenols with carnosic acid and rosmarinic acid found in highest concentrations. The present review summarizes the existing in vitro and in vivo studies focusing on the anticancer effects of rosemary extr …
Rosemary extract contains many polyphenols with carnosic acid and rosmarinic acid found in highest concen …
Anti-Carcinogenic Effects of Carnosol-An Updated Review.
Samarghandian S, Azimi-Nezhad M, Farkhondeh T. Samarghandian S, et al. Curr Drug Discov Technol. 2018;15(1):32-40. doi: 10.2174/1570163814666170413121732. Curr Drug Discov Technol. 2018. PMID: 28412913 Review.
BACKGROUND: Despite the newly treatment procedures, cancer is considered as the main health threat nowadays and, therefore, new therapeutic options such as traditional medicine should be investigated. Rosemary (Rosmarinus officinalis L.) has been found to possess antitumor …
BACKGROUND: Despite the newly treatment procedures, cancer is considered as the main health threat nowadays and, therefore, new therapeutic …
Nutraceutical antioxidants as novel neuroprotective agents.
Kelsey NA, Wilkins HM, Linseman DA. Kelsey NA, et al. Molecules. 2010 Nov 3;15(11):7792-814. doi: 10.3390/molecules15117792. Molecules. 2010. PMID: 21060289 Free PMC article. Review.
These natural antioxidants fall into several distinct groups based on their chemical structures: (1) flavonoid polyphenols like epigallocatechin 3-gallate (EGCG) from green tea and quercetin from apples; (2) non-flavonoid polyphenols such as curcumin from tumeric and resveratrol …
These natural antioxidants fall into several distinct groups based on their chemical structures: (1) flavonoid polyphenols like epigallocate …
54 results