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1989 1
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13 results

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Page 1
Bioavailability of encapsulated rosmarinic acid and beta-Carotene in beef Sausages: A Caco-2 cell study.
Bako HK, Ibeogu IH, Yar MS, Li C. Bako HK, et al. Food Res Int. 2025 Jan;200:115430. doi: 10.1016/j.foodres.2024.115430. Epub 2024 Nov 30. Food Res Int. 2025. PMID: 39779074
In this study, we examined the bioavailability and functionality of rosmarinic acid and beta-carotene in beef sausages using Caco-2 cell models. ...During the total absorption of sample C, rosmarinic acid was more bioavailable than …
In this study, we examined the bioavailability and functionality of rosmarinic acid and beta-carotene in beef sausages …
Short Chain ( C4) Esterification Increases Bioavailability of Rosmarinic Acid and Its Potency to Inhibit Vascular Smooth Muscle Cell Proliferation.
Blažević T, Reznicek G, Ding L, Yang G, Haiss P, Heiss EH, Dirsch VM, Liu R. Blažević T, et al. Front Pharmacol. 2021 Jan 21;11:609756. doi: 10.3389/fphar.2020.609756. eCollection 2020. Front Pharmacol. 2021. PMID: 33551811 Free PMC article.
Aiming to improve the pharmacokinetic profile of rosmarinic acid and its activity on vascular smooth muscle cell proliferation, we generated a series of rosmarinic acid esters with increasing alkyl chain length ranging from C1 to C12. UHPLC-MS/M …
Aiming to improve the pharmacokinetic profile of rosmarinic acid and its activity on vascular smooth muscle cell prolif …
Percutaneous absorption of rosmarinic acid in the rat.
Ritschel WA, Starzacher A, Sabouni A, Hussain AS, Koch HP. Ritschel WA, et al. Methods Find Exp Clin Pharmacol. 1989 May;11(5):345-52. Methods Find Exp Clin Pharmacol. 1989. PMID: 2755281
Rosmarinic acid (RA) is a nonsteroidal anti-inflammatory agent. The purpose of the study was to investigate the transdermal absorption of RA, its tissue distribution and absolute bioavailability. ...Upon topical administration of RA in form of a W/O oi …
Rosmarinic acid (RA) is a nonsteroidal anti-inflammatory agent. The purpose of the study was to investigate the transdermal …
Oral Pharmacokinetics of Hydroxycinnamic Acids: An Updated Review.
Veras KS, Fachel FNS, de Araújo BV, Teixeira HF, Koester LS. Veras KS, et al. Pharmaceutics. 2022 Nov 30;14(12):2663. doi: 10.3390/pharmaceutics14122663. Pharmaceutics. 2022. PMID: 36559157 Free PMC article. Review.
Hydroxycinnamic acids (HCAs) such as caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic acid (FA) and rosmarinic acid (RA) are natural phenolic acids with widespread distribution in vegetal foods and well-docu …
Hydroxycinnamic acids (HCAs) such as caffeic acid (CA), chlorogenic acid (CGA), coumaric acid (COA) isomers, ferulic …
Ethyl lauroyl arginate-based hydrophobic ion pair complex in lipid nanocapsules: A novel oral delivery approach of rosmarinic acid for enhanced permeability and bioavailability.
Gad HA, Ishak RAH, Labib RM, Kamel AO. Gad HA, et al. Int J Pharm. 2023 Jan 5;630:122388. doi: 10.1016/j.ijpharm.2022.122388. Epub 2022 Nov 11. Int J Pharm. 2023. PMID: 36375682
Limited oral bioavailability due to high hydrophilicity restricts the beneficial use of Rosmaranic acid (RM) that is characterized by many biological and pharmacological effects. ...In conclusion, the HIP complex and HIP loaded LNCs prosper in enhancing the p …
Limited oral bioavailability due to high hydrophilicity restricts the beneficial use of Rosmaranic acid (RM) that is character …
Bioavailability and nutrikinetics of rosemary tea phenolic compounds in humans.
Achour M, Bravo L, Sarriá B, Ben Fredj M, Nouira M, Mtiraoui A, Saguem S, Mateos R. Achour M, et al. Food Res Int. 2021 Jan;139:109815. doi: 10.1016/j.foodres.2020.109815. Epub 2020 Oct 20. Food Res Int. 2021. PMID: 33509454
Few un-metabolized compounds were detected since rosemary polyphenols were extensively metabolized into phase II conjugates, with rapid appearance and clearance in plasma, pointing to small intestinal absorption. Phase II derivatives of caffeic acid showed kinetics …
Few un-metabolized compounds were detected since rosemary polyphenols were extensively metabolized into phase II conjugates, with rapid appe …
Permeability of rosmarinic acid in Prunella vulgaris and ursolic acid in Salvia officinalis extracts across Caco-2 cell monolayers.
Qiang Z, Ye Z, Hauck C, Murphy PA, McCoy JA, Widrlechner MP, Reddy MB, Hendrich S. Qiang Z, et al. J Ethnopharmacol. 2011 Oct 11;137(3):1107-12. doi: 10.1016/j.jep.2011.07.037. Epub 2011 Jul 20. J Ethnopharmacol. 2011. PMID: 21798330 Free PMC article.
ETHNOPHARMACOLOGICAL RELEVANCE: Rosmarinic acid (RA), a caffeic acid-related compound found in high concentrations in Prunella vulgaris (self-heal), and ursolic acid (UA), a pentacyclic triterpene acid concentrated in Salvia officinalis (sage), …
ETHNOPHARMACOLOGICAL RELEVANCE: Rosmarinic acid (RA), a caffeic acid-related compound found in high concentrations in P …
Anti-Inflammatory and Antioxidant Activities from the Basolateral Fraction of Caco-2 Cells Exposed to a Rosmarinic Acid Enriched Extract.
Villalva M, Jaime L, Aguado E, Nieto JA, Reglero G, Santoyo S. Villalva M, et al. J Agric Food Chem. 2018 Feb 7;66(5):1167-1174. doi: 10.1021/acs.jafc.7b06008. Epub 2018 Jan 30. J Agric Food Chem. 2018. PMID: 29345918
The potential use of Origanum majorana L. as a source of bioavailable phenolic compounds, specifically rosmarinic acid (RA), has been evaluated. Phenolic bioavailability was tested using an in vitro digestion process followed by a Caco-2 cellular model …
The potential use of Origanum majorana L. as a source of bioavailable phenolic compounds, specifically rosmarinic acid …
Orally administered rosmarinic acid is present as the conjugated and/or methylated forms in plasma, and is degraded and metabolized to conjugated forms of caffeic acid, ferulic acid and m-coumaric acid.
Baba S, Osakabe N, Natsume M, Terao J. Baba S, et al. Life Sci. 2004 May 28;75(2):165-78. doi: 10.1016/j.lfs.2003.11.028. Life Sci. 2004. PMID: 15120569
Rosmarinic acid (RA) is contained in various Lamiaceae herbs used commonly as culinary herbs. Although RA has various potent physiological actions, little is known on its bioavailability. We therefore investigated the absorption and metabolism of orall …
Rosmarinic acid (RA) is contained in various Lamiaceae herbs used commonly as culinary herbs. Although RA has various potent p …
Comparative pharmacokinetic and bioavailability studies of three salvianolic acids after the administration of Salviae miltiorrhizae alone or with synthetical borneol in rats.
Lai XJ, Zhang L, Li JS, Liu HQ, Liu XH, Di LQ, Cai BC, Chen LH. Lai XJ, et al. Fitoterapia. 2011 Sep;82(6):883-8. doi: 10.1016/j.fitote.2011.04.015. Epub 2011 May 4. Fitoterapia. 2011. PMID: 21575691
The purpose of this study was to investigate the effects of borneol on the pharmacokinetic and bioavailability of S. miltiorrhizae. The pharmacokinetics studying on rosmarinic acid, salvianolic acid A and salvianolic acid B which a …
The purpose of this study was to investigate the effects of borneol on the pharmacokinetic and bioavailability of S. miltiorrh …
13 results