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501 results

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Page 1
Biological effects of rutin on skin aging.
Choi SJ, Lee SN, Kim K, Joo da H, Shin S, Lee J, Lee HK, Kim J, Kwon SB, Kim MJ, Ahn KJ, An IS, An S, Cha HJ. Choi SJ, et al. Int J Mol Med. 2016 Jul;38(1):357-63. doi: 10.3892/ijmm.2016.2604. Epub 2016 May 24. Int J Mol Med. 2016. PMID: 27220601 Clinical Trial.
To examine the effects of rutin in vivo, rutin-containing cream was applied to human skin. A double-blind clinical study was conducted in 40 subjects aged between 30-50 years and divided into control and experimental groups. ...Furthermore, rutin incre …
To examine the effects of rutin in vivo, rutin-containing cream was applied to human skin. A double-blind clinical stud …
Bilayered skin substitute incorporating rutin nanoparticles for antioxidant, anti-inflammatory, and anti-fibrotic effect.
Saha R, Patkar S, Pillai MM, Tayalia P. Saha R, et al. Biomater Adv. 2023 Jul;150:213432. doi: 10.1016/j.bioadv.2023.213432. Epub 2023 Apr 19. Biomater Adv. 2023. PMID: 37119696
Therefore, it is imperative to curb hyperinflammation to expedite wound healing. In this study, rutin nanoparticles (RNPs) were synthesized without an encapsulant and incorporated into eggshell membrane powder-crosslinked gelatin-chitosan cryogels to impart antioxidant and …
Therefore, it is imperative to curb hyperinflammation to expedite wound healing. In this study, rutin nanoparticles (RNPs) were synth …
Rutin ameliorates imiquimod-induced psoriasis-like skin lesions by inhibiting oxidative stress injury and the inflammatory response in mice via the Keap1/Nrf2 signaling pathway.
Hu Y, Liang X, Li X, Han Y, Lang G. Hu Y, et al. Sci Rep. 2025 Jul 1;15(1):20712. doi: 10.1038/s41598-025-08451-y. Sci Rep. 2025. PMID: 40596643 Free PMC article.
Psoriasis is a chronic inflammatory skin disease with a high world-wide incidence. Rutin, a natural citrus flavonoid glycoside, has been shown to have anti-inflammatory and antioxidant properties. ...Our data evidence that rutin ameliorated IMQ-induced psoria …
Psoriasis is a chronic inflammatory skin disease with a high world-wide incidence. Rutin, a natural citrus flavonoid glycoside …
Antioxidant and Skin Whitening Activities of Sub- and Super-Critical Water Treated Rutin.
Jo YJ, Yoo DH, Lee IC, Lee J, Jeong HS. Jo YJ, et al. Molecules. 2022 Aug 25;27(17):5441. doi: 10.3390/molecules27175441. Molecules. 2022. PMID: 36080207 Free PMC article.
We focused on the functional components, antioxidant activity, skin-whitening, and anti-wrinkle properties of subcritical and supercritical water (SCW)-treated rutin. ...These results indicate that SCW treatment could be used to develop cosmetic materials and functi …
We focused on the functional components, antioxidant activity, skin-whitening, and anti-wrinkle properties of subcritical and supercr …
Photoprotective effect of solid lipid nanoparticles of rutin against UVB radiation damage on skin biopsies and tissue-engineered skin.
Martins RM, de Siqueira Martins S, Barbosa GLF, Fonseca MJV, Rochette PJ, Moulin VJ, de Freitas LAP. Martins RM, et al. J Microencapsul. 2022 Nov-Dec;39(7-8):668-679. doi: 10.1080/02652048.2022.2156631. Epub 2022 Dec 20. J Microencapsul. 2022. PMID: 36476253
The rutin SLNs were able to efficiently protect against UVB induced in the analysed parameters in both skin models. Furthermore, the rutin SLNs inhibited lipid peroxidation and metalloproteinase formation. These results support the use of rutin SLNs as …
The rutin SLNs were able to efficiently protect against UVB induced in the analysed parameters in both skin models. Furthermor …
Time-dependent effect of rutin on skin fibroblasts membrane disruption following UV radiation.
Gęgotek A, Bielawska K, Biernacki M, Dobrzyńska I, Skrzydlewska E. Gęgotek A, et al. Redox Biol. 2017 Aug;12:733-744. doi: 10.1016/j.redox.2017.04.014. Epub 2017 Apr 9. Redox Biol. 2017. PMID: 28412651 Free PMC article.
The aim of this study was to determine the effects of natural, previously extensively examined, polyphenol with antioxidant properties - rutin, on UV-induced skin fibroblasts membrane disruption. Accordingly, fibroblasts exposed to UVA and UVB irradiation were incub …
The aim of this study was to determine the effects of natural, previously extensively examined, polyphenol with antioxidant properties - …
Rutin-Loaded Transethosomal Gel for Topical Application: A Comprehensive Analysis of Skin Permeation and Antimicrobial Efficacy.
Aldawsari MF, Alam A, Imran M. Aldawsari MF, et al. ACS Omega. 2024 Jun 10;9(25):27300-27311. doi: 10.1021/acsomega.4c01718. eCollection 2024 Jun 25. ACS Omega. 2024. PMID: 38947795 Free PMC article.
The drug that permeated the skin from Opt-RUT-TEG (935.25 10.49 mug/cm(2)) was significantly higher than the permeability from RUT-Suspension gel (522.57 6.79 mug/cm(2)). ...The investigation highlights the significant therapeutic possibilities of rutin in a tra …
The drug that permeated the skin from Opt-RUT-TEG (935.25 10.49 mug/cm(2)) was significantly higher than the permeability from RUT- …
Novel Nanotechnological Strategies for Skin Anti-aging.
Pozos-Nonato S, Domínguez-Delgado CL, Campos-Santander KA, Benavides AA, Pacheco-Ortin SM, Higuera-Piedrahita RI, Resendiz-González G, Molina-Trinidad EM. Pozos-Nonato S, et al. Curr Pharm Biotechnol. 2023;24(11):1397-1419. doi: 10.2174/1389201024666221223095315. Curr Pharm Biotechnol. 2023. PMID: 36567280 Review.
These nanotechnological strategies can target cellular/ molecular pathways of the skin affected by the aging process. However, a review of these strategies is required to discuss their efficacy/safety and establish the needs for further research. ...This encapsulation has …
These nanotechnological strategies can target cellular/ molecular pathways of the skin affected by the aging process. However, a revi …
Rutin-decorated molybdenum disulfide/hyaluronic acid methylprenyl hydrogel photothermal antibacterial therapy promotes skin wound repair.
Dong X, Wan F, Zhang J, Zhuo C, Zhou N. Dong X, et al. Biomed Phys Eng Express. 2025 Aug 7;11(5). doi: 10.1088/2057-1976/adf445. Biomed Phys Eng Express. 2025. PMID: 40712593
This study aimed to develop a multifunctional hydrogel for skin wound healing by encapsulating rutin-modified molybdenum disulfide (MoS(2)) within methacrylated hyaluronic acid (HAMA). ...The sustained release of rutin synergistically enhances photothermal an …
This study aimed to develop a multifunctional hydrogel for skin wound healing by encapsulating rutin-modified molybdenum disul …
Apple Extract (Malus sp.) and Rutin as Photochemopreventive Agents: Evaluation of Ultraviolet B-Induced Alterations on Skin Biopsies and Tissue-Engineered Skin.
Martins RM, Alves GAD, Martins SS, de Freitas LAP, Rochette PJ, Moulin VJ, Fonseca MJV. Martins RM, et al. Rejuvenation Res. 2020 Dec;23(6):465-475. doi: 10.1089/rej.2019.2219. Epub 2020 May 18. Rejuvenation Res. 2020. PMID: 32242497 Free article.
In this study, we evaluated the efficacy of two topical formulations containing 1.25% of Malus sp. extract and the equivalent amount of rutin (0.75%). The photochemopreventive effect was assessed on two three-dimensional (3D) skin models, that is, ex vivo skin …
In this study, we evaluated the efficacy of two topical formulations containing 1.25% of Malus sp. extract and the equivalent amount of r …
501 results