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Salvia miltiorrhiza and Tanshinone IIA reduce endothelial inflammation and atherosclerotic plaque formation through inhibiting COX-2.
Ma X, Zhang L, Gao F, Jia W, Li C. Ma X, et al. Biomed Pharmacother. 2023 Nov;167:115501. doi: 10.1016/j.biopha.2023.115501. Epub 2023 Sep 15. Biomed Pharmacother. 2023. PMID: 37713995 Free article.
The mechanisms of Salvia miltiorrhiza (SM) and Tanshinone IIA (Tan IIA) in the treatment of atherosclerosis was examined by combining network pharmacology and molecular biology experiments. ...We have demonstrated for the first time that Tan IIA plays a vital …
The mechanisms of Salvia miltiorrhiza (SM) and Tanshinone IIA (Tan IIA) in the treatment of atherosclerosis was examine …
Salvia miltiorrhiza Extract Prevents the Occurrence of Early Atherosclerosis in Apoe -/- Mice via TLR4/ NF-kB Pathway.
Wu R, Zhang L, Xu H, Chen H, Zhao W, Zhou Y, Zhou L, Wu J, An S. Wu R, et al. Cardiovasc Hematol Agents Med Chem. 2023;21(3):232-239. doi: 10.2174/1871525721666230206112134. Cardiovasc Hematol Agents Med Chem. 2023. PMID: 36748219 Free PMC article.
Although aqueous extract from Salvia miltiorrhiza has been traditionally used to treat cardiovascular diseases, the efficacy and function of the optimal ratio of SABP in preventing and treating cardiovascular diseases remain unknown. This study aims to explore the a …
Although aqueous extract from Salvia miltiorrhiza has been traditionally used to treat cardiovascular diseases, the efficacy a …
Pharmacological Activity and Mechanism of Tanshinone IIA in Related Diseases.
Guo R, Li L, Su J, Li S, Duncan SE, Liu Z, Fan G. Guo R, et al. Drug Des Devel Ther. 2020 Nov 5;14:4735-4748. doi: 10.2147/DDDT.S266911. eCollection 2020. Drug Des Devel Ther. 2020. PMID: 33192051 Free PMC article. Review.
Salvia miltiorrhiza: (Danshen) is a significant (traditional Chinese medication) natural remedy, enhancing blood circulation and clear blood stasis. ...Tanshinone IIA (tan-IIA) is the main fat-soluble component of Salvia miltiorrhiza. Modern pharmacolo …
Salvia miltiorrhiza: (Danshen) is a significant (traditional Chinese medication) natural remedy, enhancing blood circulation a …
Salvia miltiorrhizaBurge (Danshen): a golden herbal medicine in cardiovascular therapeutics.
Li ZM, Xu SW, Liu PQ. Li ZM, et al. Acta Pharmacol Sin. 2018 May;39(5):802-824. doi: 10.1038/aps.2017.193. Epub 2018 Apr 26. Acta Pharmacol Sin. 2018. PMID: 29698387 Free PMC article. Review.
Salvia miltiorrhiza Burge (Danshen) is an eminent medicinal herb that possesses broad cardiovascular and cerebrovascular protective actions and has been used in Asian countries for many centuries. Accumulating evidence suggests that Danshen and its components preven …
Salvia miltiorrhiza Burge (Danshen) is an eminent medicinal herb that possesses broad cardiovascular and cerebrovascular prote …
Salvia miltiorrhiza in Treating Cardiovascular Diseases: A Review on Its Pharmacological and Clinical Applications.
Ren J, Fu L, Nile SH, Zhang J, Kai G. Ren J, et al. Front Pharmacol. 2019 Jul 5;10:753. doi: 10.3389/fphar.2019.00753. eCollection 2019. Front Pharmacol. 2019. PMID: 31338034 Free PMC article. Review.
Bioactive chemical constitutes from the root of Salvia miltiorrhiza classified in two major groups, viz., liposoluble tanshinones and water-soluble phenolics. ...Moreover, we also provided details about the clinical applications of S. miltiorrhiza preparation …
Bioactive chemical constitutes from the root of Salvia miltiorrhiza classified in two major groups, viz., liposoluble tanshino …
Danshen (Salvia miltiorrhiza Bunge): A Prospective Healing Sage for Cardiovascular Diseases.
Chen W, Chen G. Chen W, et al. Curr Pharm Des. 2017;23(34):5125-5135. doi: 10.2174/1381612823666170822101112. Curr Pharm Des. 2017. PMID: 28828985 Review.
Danshen (Salvia miltiorrhiza Bunge) is a valued herbal plant in the Traditional Chinese Medicine. The dried root of this plant (Radix Salvia miltiorrhiza), either alone or in combination with other herbal ingredients, has been used for hundreds of year …
Danshen (Salvia miltiorrhiza Bunge) is a valued herbal plant in the Traditional Chinese Medicine. The dried root of this plant …
Dingxin Recipe IV attenuates atherosclerosis by regulating lipid metabolism through LXR-alpha/SREBP1 pathway and modulating the gut microbiota in ApoE(-/-) mice fed with HFD.
Zhang Y, Gu Y, Chen Y, Huang Z, Li M, Jiang W, Chen J, Rao W, Luo S, Chen Y, Chen J, Li L, Jia Y, Liu M, Zhou F. Zhang Y, et al. J Ethnopharmacol. 2021 Feb 10;266:113436. doi: 10.1016/j.jep.2020.113436. Epub 2020 Oct 1. J Ethnopharmacol. 2021. PMID: 33011372 Free article.
However, the mechanism of DXR IV in atherosclerosis is unclear. AIM OF THE STUDY: This study aimed to illustrate whether DXR IV improve atherosclerosis through modulating the lipid metabolism and gut microbiota in atherosclerosis mice. ...The decroation of DX …
However, the mechanism of DXR IV in atherosclerosis is unclear. AIM OF THE STUDY: This study aimed to illustrate whether DXR IV impro …
Combination of atorvastatin or hydrochlorothiazide/amlodipine with Salvia miltiorrhiza (Danshen) and Pueraria lobata (Gegen) for atherosclerosis, hyperlipidaemia, and hypertension: a preclinical in vivo study (abridged secondary publication).
Cheung DWS, Koon JCM, Wong PH, Yau KC, Wat ECL, Chan JYW, Lau VKM, Ko ECH, Waye MMY, Fung KP. Cheung DWS, et al. Hong Kong Med J. 2021 Jun;27 Suppl 2(3):18-22. Hong Kong Med J. 2021. PMID: 34075886 Free article. No abstract available.
Extract of high hydrostatic pressure-treated danshen (Salvia miltiorrhiza) ameliorates atherosclerosis via autophagy induction.
Ko M, Oh GT, Park J, Kwon HJ. Ko M, et al. BMB Rep. 2020 Dec;53(12):652-657. doi: 10.5483/BMBRep.2020.53.12.184. BMB Rep. 2020. PMID: 33172543 Free PMC article.
Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries for its pharmacological activities (e.g., amelioration of cardiovascular diseases). ...
Danshen (Salvia miltiorrhiza) is a traditional medicinal plant widely used in Asian countries for its pharmacological activiti …
Tanshinone IIA alleviates atherosclerosis in LDLR(-/-) mice by regulating efferocytosis of macrophages.
Wang J, Zhang Y, Feng X, Du M, Li S, Chang X, Liu P. Wang J, et al. Front Pharmacol. 2023 Oct 11;14:1233709. doi: 10.3389/fphar.2023.1233709. eCollection 2023. Front Pharmacol. 2023. PMID: 37886125 Free PMC article.
Background: Tanshinone IIA (TIIA) is the major lipid-soluble active ingredient of the traditional Chinese medicine Salvia miltiorrhiza, which slows down atherosclerosis (AS). However, it remains unclear whether TIIA has the potential to enhance macrophage eff …
Background: Tanshinone IIA (TIIA) is the major lipid-soluble active ingredient of the traditional Chinese medicine Salvia miltiorr …
171 results