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Vitamin D Insufficiency and Deficiency and Mortality from Respiratory Diseases in a Cohort of Older Adults: Potential for Limiting the Death Toll during and beyond the COVID-19 Pandemic?
Brenner H, Holleczek B, Schöttker B. Brenner H, et al. Among authors: schottker b. Nutrients. 2020 Aug 18;12(8):2488. doi: 10.3390/nu12082488. Nutrients. 2020. PMID: 32824839 Free PMC article.
The COVID-19 pandemic goes along with increased mortality from acute respiratory disease. It has been suggested that vitamin D(3) supplementation might help to reduce respiratory disease mortality. ...Overall, 41% (95% confidence interval: 20-58%) of r …
The COVID-19 pandemic goes along with increased mortality from acute respiratory disease. It has been suggested that vitamin
Efficacy of vitamin D(3) supplementation on cancer mortality in the general population and the prognosis of patients with cancer: protocol of a systematic review and individual patient data meta-analysis of randomised controlled trials.
Schöttker B, Kuznia S, Brenner H. Schöttker B, et al. BMJ Open. 2021 Jan 13;11(1):e041607. doi: 10.1136/bmjopen-2020-041607. BMJ Open. 2021. PMID: 33441357 Free PMC article.
INTRODUCTION: Vitamin D insufficiency is much more common among patients with cancer than the general population. Previous meta-analyses of controlled trials showed an approximately 15% reduction of cancer mortality by vitamin D supplementation …
INTRODUCTION: Vitamin D insufficiency is much more common among patients with cancer than the general population. Previous met …
Serum 25-hydroxyvitamin D levels and overall mortality. A systematic review and meta-analysis of prospective cohort studies.
Schöttker B, Ball D, Gellert C, Brenner H. Schöttker B, et al. Ageing Res Rev. 2013 Mar;12(2):708-18. doi: 10.1016/j.arr.2012.02.004. Epub 2012 Feb 17. Ageing Res Rev. 2013. PMID: 22343489 Review.
In meta-analysis, 25(OH)D levels were significantly inversely associated with all-cause mortality with a pooled HR of 0.92 (95% confidence interval: 0.89-0.95) for a 20 nmol/l increase in 25(OH)D levels. ...This agrees with results from meta-analyses on rando …
In meta-analysis, 25(OH)D levels were significantly inversely associated with all-cause mortality with a pooled HR of 0.92 (95 …
Vitamin D status and epigenetic-based mortality risk score: strong independent and joint prediction of all-cause mortality in a population-based cohort study.
Gao X, Zhang Y, Schöttker B, Brenner H. Gao X, et al. Among authors: schottker b. Clin Epigenetics. 2018 Jun 20;10:84. doi: 10.1186/s13148-018-0515-y. eCollection 2018. Clin Epigenetics. 2018. PMID: 29977410 Free PMC article.
BACKGROUND: Vitamin D deficiency and insufficiency have been established to be strongly associated with increased overall mortality and deaths from specific aging-related diseases. ...CONCLUSIONS: This study suggests that vitamin D and the MS ar …
BACKGROUND: Vitamin D deficiency and insufficiency have been established to be strongly associated with increased overall m
Genetic Variants in the Vitamin D Pathway, 25(OH)D Levels, and Mortality in a Large Population-Based Cohort Study.
Ordóñez-Mena JM, Maalmi H, Schöttker B, Saum KU, Holleczek B, Wang TJ, Burwinkel B, Brenner H. Ordóñez-Mena JM, et al. Among authors: schottker b. J Clin Endocrinol Metab. 2017 Feb 1;102(2):470-477. doi: 10.1210/jc.2016-2468. J Clin Endocrinol Metab. 2017. PMID: 27732326
An association of vitamin D-related genetic variants with all-cause mortality could strengthen the claims of causality, because this association is assumed to be unaffected by confounding. OBJECTIVE: To assess the associations of low 25(OH)D with mo
An association of vitamin D-related genetic variants with all-cause mortality could strengthen the claims of causality, …
Vitamin D Supplementation Trials Aimed at Reducing Mortality Have Much Higher Power When Focusing on People with Low Serum 25-Hydroxyvitamin D Concentrations.
Brenner H, Jansen L, Saum KU, Holleczek B, Schöttker B. Brenner H, et al. Among authors: schottker b. J Nutr. 2017 Jul;147(7):1325-1333. doi: 10.3945/jn.117.250191. Epub 2017 May 24. J Nutr. 2017. PMID: 28539415
Background: Evidence of an inverse association between serum vitamin D and mortality from epidemiological studies has prompted efforts to reduce mortality by vitamin D supplementation, either in targeted interventions for people with v
Background: Evidence of an inverse association between serum vitamin D and mortality from epidemiological studies has p …
Vitamin D and mortality: meta-analysis of individual participant data from a large consortium of cohort studies from Europe and the United States.
Schöttker B, Jorde R, Peasey A, Thorand B, Jansen EH, Groot Ld, Streppel M, Gardiner J, Ordóñez-Mena JM, Perna L, Wilsgaard T, Rathmann W, Feskens E, Kampman E, Siganos G, Njølstad I, Mathiesen EB, Kubínová R, Pająk A, Topor-Madry R, Tamosiunas A, Hughes M, Kee F, Bobak M, Trichopoulou A, Boffetta P, Brenner H; Consortium on Health and Ageing: Network of Cohorts in Europe and the United States. Schöttker B, et al. BMJ. 2014 Jun 17;348:g3656. doi: 10.1136/bmj.g3656. BMJ. 2014. PMID: 24938302 Free PMC article.
OBJECTIVE: To investigate the association between serum 25-hydroxyvitamin D concentrations (25(OH)D) and mortality in a large consortium of cohort studies paying particular attention to potential age, sex, season, and country differences. ...Results from a lo …
OBJECTIVE: To investigate the association between serum 25-hydroxyvitamin D concentrations (25(OH)D) and mortality in a …
Is vitamin D deficiency a cause of increased morbidity and mortality at older age or simply an indicator of poor health?
Schöttker B, Saum KU, Perna L, Ordóñez-Mena JM, Holleczek B, Brenner H. Schöttker B, et al. Eur J Epidemiol. 2014 Mar;29(3):199-210. doi: 10.1007/s10654-014-9894-3. Epub 2014 Mar 29. Eur J Epidemiol. 2014. PMID: 24682834
To assess whether vitamin D deficiency is a cause of increased morbidity and mortality or simply an indicator of poor health, we assessed (1) the cross-sectional and longitudinal association of vitamin D deficiency with self-rated health (SRH) a …
To assess whether vitamin D deficiency is a cause of increased morbidity and mortality or simply an indicator of poor h …
Vitamin D receptor polymorphism and colorectal cancer-specific and all-cause mortality.
Perna L, Hoffmeister M, Schöttker B, Arndt V, Haug U, Holleczek B, Burwinkel B, Ordóñez-Mena JM, Brenner H. Perna L, et al. Among authors: schottker b. Cancer Epidemiol. 2013 Dec;37(6):905-7. doi: 10.1016/j.canep.2013.09.007. Epub 2013 Sep 27. Cancer Epidemiol. 2013. PMID: 24075799
BACKGROUND: The vitamin D receptor (VDR) gene is present in colorectal cancer (CRC) cells and its genetic variants have been associated with an increased risk of CRC. ...RESULTS: No association was found between VDR polymorphism and CRC specific and all-cause mor
BACKGROUND: The vitamin D receptor (VDR) gene is present in colorectal cancer (CRC) cells and its genetic variants have been a …
Serum 25-hydroxyvitamin D levels and survival in colorectal and breast cancer patients: systematic review and meta-analysis of prospective cohort studies.
Maalmi H, Ordóñez-Mena JM, Schöttker B, Brenner H. Maalmi H, et al. Among authors: schottker b. Eur J Cancer. 2014 May;50(8):1510-21. doi: 10.1016/j.ejca.2014.02.006. Epub 2014 Feb 28. Eur J Cancer. 2014. PMID: 24582912 Review.
AIM: To estimate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and survival among colorectal and breast cancer patients. ...Randomised controlled trials are needed to evaluate whether vitamin D supplementation can improve survival …
AIM: To estimate the association between serum 25-hydroxyvitamin D (25(OH)D) levels and survival among colorectal and breast c …
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