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Human platelet lysate can replace fetal bovine serum for clinical-scale expansion of functional mesenchymal stromal cells.
Schallmoser K, Bartmann C, Rohde E, Reinisch A, Kashofer K, Stadelmeyer E, Drexler C, Lanzer G, Linkesch W, Strunk D. Schallmoser K, et al. Transfusion. 2007 Aug;47(8):1436-46. doi: 10.1111/j.1537-2995.2007.01220.x. Transfusion. 2007. PMID: 17655588
Translation of auspicious experimental results into clinical applications has been limited by the dependence of MSC propagation from fetal bovine serum (FBS). STUDY DESIGN AND METHODS: The capacity of human platelet lysate (HPL) to replace FBS for clin …
Translation of auspicious experimental results into clinical applications has been limited by the dependence of MSC propagation from fetal b …
Generation of a pool of human platelet lysate and efficient use in cell culture.
Schallmoser K, Strunk D. Schallmoser K, et al. Methods Mol Biol. 2013;946:349-62. doi: 10.1007/978-1-62703-128-8_22. Methods Mol Biol. 2013. PMID: 23179843
Human platelets represent a promising source of bioactive substances as growth factors not just for in vivo wound healing and tissue repair, but also for the expansion of human stem and progenitor cells in vitro. The replacement of fetal bovine serum (FBS) as a stan …
Human platelets represent a promising source of bioactive substances as growth factors not just for in vivo wound healing and tissue repair, …