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209 results

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Page 1
Getting STAT-isfaction.
Scharfman HE. Scharfman HE. Epilepsy Curr. 2025 Jul 17;25(5):353-355. doi: 10.1177/15357597251352993. eCollection 2025 Sep-Oct. Epilepsy Curr. 2025. PMID: 40688444 Free PMC article. No abstract available.
Adenosine Makes a Scene.
Scharfman HE. Scharfman HE. Epilepsy Curr. 2025 Apr 16;25(3):198-200. doi: 10.1177/15357597251323126. eCollection 2025 May-Jun. Epilepsy Curr. 2025. PMID: 40256115 Free PMC article. No abstract available.
Field EPSPs of dentate gyrus granule cells studied by selective optogenetic activation of hilar mossy cells in hippocampal slices.
Bernstein HL, Lu YL, Botterill JJ, Duffy ÁM, LaFrancois JJ, Scharfman HE. Bernstein HL, et al. Among authors: scharfman he. bioRxiv [Preprint]. 2024 Nov 8:2024.11.08.622679. doi: 10.1101/2024.11.08.622679. bioRxiv. 2024. Update in: Hippocampus. 2025 Jan;35(1):e23652. doi: 10.1002/hipo.23652. PMID: 39574724 Free PMC article. Updated. Preprint.
Increasing adult-born neurons protects mice from epilepsy.
Jain S, LaFrancois JJ, Gerencer K, Botterill JJ, Kennedy M, Criscuolo C, Scharfman HE. Jain S, et al. Among authors: scharfman he. Elife. 2024 Oct 24;12:RP90893. doi: 10.7554/eLife.90893. Elife. 2024. PMID: 39446467 Free PMC article.
Increased excitability of dentate gyrus mossy cells occurs early in life in the Tg2576 model of Alzheimer's disease.
Alcantara-Gonzalez D, Kennedy M, Criscuolo C, Botterill J, Scharfman HE. Alcantara-Gonzalez D, et al. Among authors: scharfman he. bioRxiv [Preprint]. 2024 Feb 12:2024.02.09.579729. doi: 10.1101/2024.02.09.579729. bioRxiv. 2024. Update in: Alzheimers Res Ther. 2025 May 15;17(1):105. doi: 10.1186/s13195-025-01747-1. PMID: 38645244 Free PMC article. Updated. Preprint.
The Diverse Roles of Mossy Cells in the Normal Brain, Epileptogenesis, and Chronic Epilepsy.
Scharfman HE. Scharfman HE. In: Noebels JL, Avoli M, Rogawski MA, Vezzani A, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies. 5th edition. New York: Oxford University Press; 2024. Chapter 23. In: Noebels JL, Avoli M, Rogawski MA, Vezzani A, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies. 5th edition. New York: Oxford University Press; 2024. Chapter 23. PMID: 39637222 Free Books & Documents. Review.
Assessments of dentate gyrus function: discoveries and debates.
Borzello M, Ramirez S, Treves A, Lee I, Scharfman H, Stark C, Knierim JJ, Rangel LM. Borzello M, et al. Among authors: scharfman h. Nat Rev Neurosci. 2023 Aug;24(8):502-517. doi: 10.1038/s41583-023-00710-z. Epub 2023 Jun 14. Nat Rev Neurosci. 2023. PMID: 37316588 Free PMC article. Review.
Stability of dentate gyrus granule cell mossy fiber BDNF protein expression with age and resistance of granule cells to Alzheimer's disease neuropathology in a mouse model.
Criscuolo C, Chartampila E, Ginsberg SD, Scharfman HE. Criscuolo C, et al. Among authors: scharfman he. bioRxiv [Preprint]. 2023 May 8:2023.05.07.539742. doi: 10.1101/2023.05.07.539742. bioRxiv. 2023. Update in: eNeuro. 2024 Mar 4;11(3):ENEURO.0192-23.2023. doi: 10.1523/ENEURO.0192-23.2023. PMID: 37214931 Free PMC article. Updated. Preprint.
Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.
Chartampila E, Elayouby KS, Leary P, LaFrancois JJ, Alcantara-Gonzalez D, Jain S, Gerencer K, Botterill JJ, Ginsberg SD, Scharfman HE. Chartampila E, et al. Among authors: scharfman he. bioRxiv [Preprint]. 2024 May 9:2023.05.12.540428. doi: 10.1101/2023.05.12.540428. bioRxiv. 2024. Update in: Elife. 2024 Jun 21;12:RP89889. doi: 10.7554/eLife.89889. PMID: 37214805 Free PMC article. Updated. Preprint.
Cannabidiol modulates excitatory-inhibitory ratio to counter hippocampal hyperactivity.
Rosenberg EC, Chamberland S, Bazelot M, Nebet ER, Wang X, McKenzie S, Jain S, Greenhill S, Wilson M, Marley N, Salah A, Bailey S, Patra PH, Rose R, Chenouard N, Sun SED, Jones D, Buzsáki G, Devinsky O, Woodhall G, Scharfman HE, Whalley BJ, Tsien RW. Rosenberg EC, et al. Among authors: scharfman he. Neuron. 2023 Apr 19;111(8):1282-1300.e8. doi: 10.1016/j.neuron.2023.01.018. Epub 2023 Feb 13. Neuron. 2023. PMID: 36787750 Free PMC article.
Regulation of BACE1 expression after injury is linked to the p75 neurotrophin receptor.
Saadipour K, Tiberi A, Lombardo S, Grajales E, Montroull L, Mañucat-Tan NB, LaFrancois J, Cammer M, Mathews PM, Scharfman HE, Liao FF, Friedman WJ, Zhou XF, Tesco G, Chao MV. Saadipour K, et al. Among authors: scharfman he. Mol Cell Neurosci. 2019 Sep;99:103395. doi: 10.1016/j.mcn.2019.103395. Epub 2019 Aug 15. Mol Cell Neurosci. 2019. PMID: 31422108 Free PMC article.
Common data elements (CDEs) for preclinical epilepsy research: Introduction to CDEs and description of core CDEs. A TASK3 report of the ILAE/AES joint translational task force.
Harte-Hargrove LC, Galanopoulou AS, French JA, Pitkänen A, Whittemore V, Scharfman HE. Harte-Hargrove LC, et al. Among authors: scharfman he. Epilepsia Open. 2018 Jul 26;3(Suppl Suppl 1):13-23. doi: 10.1002/epi4.12234. eCollection 2018 Nov. Epilepsia Open. 2018. PMID: 30450483 Free PMC article.
A companion to the preclinical common data elements for physiologic data in rodent epilepsy models. A report of the TASK3 Physiology Working Group of the ILAE/AES Joint Translational Task Force.
Gorter JA, van Vliet EA, Dedeurwaerdere S, Buchanan GF, Friedman D, Borges K, Grabenstatter H, Lukasiuk K, Scharfman HE, Nehlig A. Gorter JA, et al. Among authors: scharfman he. Epilepsia Open. 2018 Oct 11;3(Suppl Suppl 1):69-89. doi: 10.1002/epi4.12261. eCollection 2018 Nov. Epilepsia Open. 2018. PMID: 30411072 Free PMC article.
Controlling learning and epilepsy together.
Scharfman HE. Scharfman HE. Science. 2018 Feb 16;359(6377):740-741. doi: 10.1126/science.aas8993. Science. 2018. PMID: 29449476 Free PMC article. No abstract available.
A Novel Neuroprotective Mechanism for Lithium That Prevents Association of the p75NTR-Sortilin Receptor Complex and Attenuates proNGF-Induced Neuronal Death In Vitro and In Vivo.
Greenwood SG, Montroull L, Volosin M, Scharfman HE, Teng KK, Light M, Torkin R, Maxfield F, Hempstead BL, Friedman WJ. Greenwood SG, et al. Among authors: scharfman he. eNeuro. 2018 Jan 17;5(1):ENEURO.0257-17.2017. doi: 10.1523/ENEURO.0257-17.2017. eCollection 2018 Jan-Feb. eNeuro. 2018. PMID: 29349290 Free PMC article.
Epilepsy as a Network Disorder (1): What can we learn from other network disorders such as autistic spectrum disorder and mood disorders?
Kanner AM, Scharfman H, Jette N, Anagnostou E, Bernard C, Camfield C, Camfield P, Legg K, Dinstein I, Giacobbe P, Friedman A, Pohlmann-Eden B. Kanner AM, et al. Among authors: scharfman h. Epilepsy Behav. 2017 Dec;77:106-113. doi: 10.1016/j.yebeh.2017.09.014. Epub 2017 Oct 26. Epilepsy Behav. 2017. PMID: 29107450 Free PMC article.
Epilepsy as a Network Disorder (2): What can we learn from other network disorders such as dementia and schizophrenia, and what are the implications for translational research?
Scharfman HE, Kanner AM, Friedman A, Blümcke I, Crocker CE, Cendes F, Diaz-Arrastia R, Förstl H, Fenton AA, Grace AA, Palop J, Morrison J, Nehlig A, Prasad A, Wilcox KS, Jette N, Pohlmann-Eden B. Scharfman HE, et al. Epilepsy Behav. 2018 Jan;78:302-312. doi: 10.1016/j.yebeh.2017.09.016. Epub 2017 Oct 31. Epilepsy Behav. 2018. PMID: 29097123 Free PMC article. Review.
The enigmatic mossy cell of the dentate gyrus.
Scharfman HE. Scharfman HE. Nat Rev Neurosci. 2016 Sep;17(9):562-75. doi: 10.1038/nrn.2016.87. Epub 2016 Jul 28. Nat Rev Neurosci. 2016. PMID: 27466143 Free PMC article. Review.
Suppression of adult neurogenesis increases the acute effects of kainic acid.
Iyengar SS, LaFrancois JJ, Friedman D, Drew LJ, Denny CA, Burghardt NS, Wu MV, Hsieh J, Hen R, Scharfman HE. Iyengar SS, et al. Among authors: scharfman he. Exp Neurol. 2015 Feb;264:135-49. doi: 10.1016/j.expneurol.2014.11.009. Epub 2014 Dec 2. Exp Neurol. 2015. PMID: 25476494 Free PMC article.
Androgen Modulation of Hippocampal Structure and Function.
Atwi S, McMahon D, Scharfman H, MacLusky NJ. Atwi S, et al. Among authors: scharfman h. Neuroscientist. 2016 Feb;22(1):46-60. doi: 10.1177/1073858414558065. Epub 2014 Nov 21. Neuroscientist. 2016. PMID: 25416742 Free PMC article. Review.
Preface.
Scharfman HE, Buckmaster PS. Scharfman HE, et al. Adv Exp Med Biol. 2014;813:xv-xviii. Adv Exp Med Biol. 2014. PMID: 25371938 No abstract available.
How can we identify ictal and interictal abnormal activity?
Fisher RS, Scharfman HE, deCurtis M. Fisher RS, et al. Among authors: scharfman he. Adv Exp Med Biol. 2014;813:3-23. doi: 10.1007/978-94-017-8914-1_1. Adv Exp Med Biol. 2014. PMID: 25012363 Free PMC article. Review.
Authors' response to letter by A. Mazarati.
Brooks-Kayal AR, Bath KG, Berg AT, Galanopoulou AS, Holmes GL, Jensen FE, Kanner AM, O'Brien TJ, Whittemore VH, Winawer MR, Patel M, Scharfman HE. Brooks-Kayal AR, et al. Among authors: scharfman he. Epilepsia. 2013 Dec;54(12):2229-30. doi: 10.1111/epi.12414. Epilepsia. 2013. PMID: 24304440 No abstract available.
Temporal Lobe Epilepsy and the BDNF Receptor, TrkB.
McNamara JO, Scharfman HE. McNamara JO, et al. Among authors: scharfman he. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. In: Noebels JL, Avoli M, Rogawski MA, Olsen RW, Delgado-Escueta AV, editors. Jasper's Basic Mechanisms of the Epilepsies [Internet]. 4th edition. Bethesda (MD): National Center for Biotechnology Information (US); 2012. PMID: 22787630 Free Books & Documents. Review.
209 results