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The connection between microbiome and schizophrenia.
Golofast B, Vales K. Golofast B, et al. Neurosci Biobehav Rev. 2020 Jan;108:712-731. doi: 10.1016/j.neubiorev.2019.12.011. Epub 2019 Dec 9. Neurosci Biobehav Rev. 2020. PMID: 31821833 Review.
That assumes the involvement of the microbiome in the pathogenesis of various CNS diseases, including schizophrenia. Given this information and the fact, that the gut microbiota is sensitive to internal and environmental influences, we have speculated that am …
That assumes the involvement of the microbiome in the pathogenesis of various CNS diseases, including schizophrenia. Given thi …
Microbiome and Schizophrenia.
Akhondzadeh S. Akhondzadeh S. Avicenna J Med Biotechnol. 2019 Oct-Dec;11(4):269. Avicenna J Med Biotechnol. 2019. PMID: 31908733 Free PMC article. No abstract available.
Metagenome-wide association of gut microbiome features for schizophrenia.
Zhu F, Ju Y, Wang W, Wang Q, Guo R, Ma Q, Sun Q, Fan Y, Xie Y, Yang Z, Jie Z, Zhao B, Xiao L, Yang L, Zhang T, Feng J, Guo L, He X, Chen Y, Chen C, Gao C, Xu X, Yang H, Wang J, Dang Y, Madsen L, Brix S, Kristiansen K, Jia H, Ma X. Zhu F, et al. Nat Commun. 2020 Mar 31;11(1):1612. doi: 10.1038/s41467-020-15457-9. Nat Commun. 2020. PMID: 32235826 Free PMC article.
However, shotgun metagenomic data from treatment-naive patients are scarce hampering comprehensive analyses of the complex interaction between the gut microbiota and the brain. Here we explore the fecal microbiome based on 90 medication-free schizophrenia pat …
However, shotgun metagenomic data from treatment-naive patients are scarce hampering comprehensive analyses of the complex interaction betwe …
Mapping genomic loci implicates genes and synaptic biology in schizophrenia.
Trubetskoy V, Pardiñas AF, Qi T, Panagiotaropoulou G, Awasthi S, Bigdeli TB, Bryois J, Chen CY, Dennison CA, Hall LS, Lam M, Watanabe K, Frei O, Ge T, Harwood JC, Koopmans F, Magnusson S, Richards AL, Sidorenko J, Wu Y, Zeng J, Grove J, Kim M, Li Z, Voloudakis G, Zhang W, Adams M, Agartz I, Atkinson EG, Agerbo E, Al Eissa M, Albus M, Alexander M, Alizadeh BZ, Alptekin K, Als TD, Amin F, Arolt V, Arrojo M, Athanasiu L, Azevedo MH, Bacanu SA, Bass NJ, Begemann M, Belliveau RA, Bene J, Benyamin B, Bergen SE, Blasi G, Bobes J, Bonassi S, Braun A, Bressan RA, Bromet EJ, Bruggeman R, Buckley PF, Buckner RL, Bybjerg-Grauholm J, Cahn W, Cairns MJ, Calkins ME, Carr VJ, Castle D, Catts SV, Chambert KD, Chan RCK, Chaumette B, Cheng W, Cheung EFC, Chong SA, Cohen D, Consoli A, Cordeiro Q, Costas J, Curtis C, Davidson M, Davis KL, de Haan L, Degenhardt F, DeLisi LE, Demontis D, Dickerson F, Dikeos D, Dinan T, Djurovic S, Duan J, Ducci G, Dudbridge F, Eriksson JG, Fañanás L, Faraone SV, Fiorentino A, Forstner A, Frank J, Freimer NB, Fromer M, Frustaci A, Gadelha A, Genovese G, Gershon ES, Giannitelli M, Giegling I, Giusti-Rodríguez P, Godard S, Goldstein JI, González Peñas J, González-Pinto A, … See abstract for full author list ➔ Trubetskoy V, et al. Nature. 2022 Apr;604(7906):502-508. doi: 10.1038/s41586-022-04434-5. Epub 2022 Apr 8. Nature. 2022. PMID: 35396580 Free PMC article.
Schizophrenia has a heritability of 60-80%(1), much of which is attributable to common risk alleles. ...We identify biological processes relevant to schizophrenia pathophysiology; show convergence of common and rare variant associations in schizophrenia and n …
Schizophrenia has a heritability of 60-80%(1), much of which is attributable to common risk alleles. ...We identify biological proces …
Gut microbiota and microbiome in schizophrenia.
Samochowiec J, Misiak B. Samochowiec J, et al. Curr Opin Psychiatry. 2021 Sep 1;34(5):503-507. doi: 10.1097/YCO.0000000000000733. Curr Opin Psychiatry. 2021. PMID: 34155149 Review.
PURPOSE OF REVIEW: Accumulating evidence indicates that there are bidirectional interactions between the gut microbiota and functioning of the central nervous system. Consequently, it has been proposed that gut microbiota alterations might play an important role in …
PURPOSE OF REVIEW: Accumulating evidence indicates that there are bidirectional interactions between the gut microbiota and functioni …
The Gut-Brain Axis in Schizophrenia: The Implications of the Gut Microbiome and SCFA Production.
Ju S, Shin Y, Han S, Kwon J, Choi TG, Kang I, Kim SS. Ju S, et al. Nutrients. 2023 Oct 16;15(20):4391. doi: 10.3390/nu15204391. Nutrients. 2023. PMID: 37892465 Free PMC article. Review.
Emerging research indicates that maternal infection or stress during pregnancy may also increase schizophrenia risk in offspring. Recent research on the gut-brain axis highlights the gut microbiome's potential influence on central nervous system (CNS) functio …
Emerging research indicates that maternal infection or stress during pregnancy may also increase schizophrenia risk in offspring. Rec …
A Comprehensive Review on the Role of the Gut Microbiome in Human Neurological Disorders.
Sorboni SG, Moghaddam HS, Jafarzadeh-Esfehani R, Soleimanpour S. Sorboni SG, et al. Clin Microbiol Rev. 2022 Jan 19;35(1):e0033820. doi: 10.1128/CMR.00338-20. Epub 2022 Jan 5. Clin Microbiol Rev. 2022. PMID: 34985325 Free PMC article. Review.
The human body is full of an extensive number of commensal microbes, consisting of bacteria, viruses, and fungi, collectively termed the human microbiome. The initial acquisition of microbiota occurs from both the external and maternal environments, and the vast maj …
The human body is full of an extensive number of commensal microbes, consisting of bacteria, viruses, and fungi, collectively termed the hum …
Is There a Link between Oropharyngeal Microbiome and Schizophrenia? A Narrative Review.
Martin S, Foulon A, El Hage W, Dufour-Rainfray D, Denis F. Martin S, et al. Int J Mol Sci. 2022 Jan 13;23(2):846. doi: 10.3390/ijms23020846. Int J Mol Sci. 2022. PMID: 35055031 Free PMC article. Review.
The study aimed to examine the impact of the oropharyngeal microbiome in the pathophysiology of schizophrenia and to clarify whether there might be a bidirectional link between the oral microbiota and the brain in a context of dysbiosis-related neuroinflammat …
The study aimed to examine the impact of the oropharyngeal microbiome in the pathophysiology of schizophrenia and to clarify w …
Microglia and microbiome in schizophrenia: can immunomodulation improve symptoms?
Juckel G, Freund N. Juckel G, et al. J Neural Transm (Vienna). 2023 Sep;130(9):1187-1193. doi: 10.1007/s00702-023-02605-w. Epub 2023 Feb 21. J Neural Transm (Vienna). 2023. PMID: 36810627 Free PMC article. Review.
In this overview, influences of microglia activation and disturbances of the microbiome in the devastating disorder schizophrenia are discussed. Despite previous assumptions of a primary neurodegenerative character of this disorder, current research underlines the i …
In this overview, influences of microglia activation and disturbances of the microbiome in the devastating disorder schizophrenia …
The Gut Microbiome in Schizophrenia and the Potential Benefits of Prebiotic and Probiotic Treatment.
Liu JCW, Gorbovskaya I, Hahn MK, Müller DJ. Liu JCW, et al. Nutrients. 2021 Mar 31;13(4):1152. doi: 10.3390/nu13041152. Nutrients. 2021. PMID: 33807241 Free PMC article. Review.
However, the relationship between GMB and schizophrenia remains unclear. In this article, we review the existing evidence surrounding the gut microbiome in schizophrenia and the potential for antipsychotics to cause adverse metabolic events by altering the gu …
However, the relationship between GMB and schizophrenia remains unclear. In this article, we review the existing evidence surrounding …
526 results