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72 results

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Page 1
Comparative Analyses of Copy-Number Variation in Autism Spectrum Disorder and Schizophrenia Reveal Etiological Overlap and Biological Insights.
Kushima I, Aleksic B, Nakatochi M, Shimamura T, Okada T, Uno Y, Morikawa M, Ishizuka K, Shiino T, Kimura H, Arioka Y, Yoshimi A, Takasaki Y, Yu Y, Nakamura Y, Yamamoto M, Iidaka T, Iritani S, Inada T, Ogawa N, Shishido E, Torii Y, Kawano N, Omura Y, Yoshikawa T, Uchiyama T, Yamamoto T, Ikeda M, Hashimoto R, Yamamori H, Yasuda Y, Someya T, Watanabe Y, Egawa J, Nunokawa A, Itokawa M, Arai M, Miyashita M, Kobori A, Suzuki M, Takahashi T, Usami M, Kodaira M, Watanabe K, Sasaki T, Kuwabara H, Tochigi M, Nishimura F, Yamasue H, Eriguchi Y, Benner S, Kojima M, Yassin W, Munesue T, Yokoyama S, Kimura R, Funabiki Y, Kosaka H, Ishitobi M, Ohmori T, Numata S, Yoshikawa T, Toyota T, Yamakawa K, Suzuki T, Inoue Y, Nakaoka K, Goto YI, Inagaki M, Hashimoto N, Kusumi I, Son S, Murai T, Ikegame T, Okada N, Kasai K, Kunimoto S, Mori D, Iwata N, Ozaki N. Kushima I, et al. Among authors: murai t, son s, hashimoto r. Cell Rep. 2018 Sep 11;24(11):2838-2856. doi: 10.1016/j.celrep.2018.08.022. Cell Rep. 2018. PMID: 30208311 Free article.
Compelling evidence in Caucasian populations suggests a role for copy-number variations (CNVs) in autism spectrum disorder (ASD) and schizophrenia (SCZ). We analyzed 1,108 ASD cases, 2,458 SCZ cases, and 2,095 controls in a Japanese population and confirmed an increased bu …
Compelling evidence in Caucasian populations suggests a role for copy-number variations (CNVs) in autism spectrum disorder (ASD) and schi …
Toward integrated understanding of salience in psychosis.
Miyata J. Miyata J. Neurobiol Dis. 2019 Nov;131:104414. doi: 10.1016/j.nbd.2019.03.002. Epub 2019 Mar 6. Neurobiol Dis. 2019. PMID: 30849509 Review.
A "salience network" comprising the bilateral insula and anterior cingulate cortex is related to the processing of stimulus salience. In addition, visual and auditory attention is well described by a "saliency map". However, so far there has been no attempt t …
A "salience network" comprising the bilateral insula and anterior cingulate cortex is related to the processing of stimulus salien …
White matter microstructural alterations across four major psychiatric disorders: mega-analysis study in 2937 individuals.
Koshiyama D, Fukunaga M, Okada N, Morita K, Nemoto K, Usui K, Yamamori H, Yasuda Y, Fujimoto M, Kudo N, Azechi H, Watanabe Y, Hashimoto N, Narita H, Kusumi I, Ohi K, Shimada T, Kataoka Y, Yamamoto M, Ozaki N, Okada G, Okamoto Y, Harada K, Matsuo K, Yamasue H, Abe O, Hashimoto R, Takahashi T, Hori T, Nakataki M, Onitsuka T, Holleran L, Jahanshad N, van Erp TGM, Turner J, Donohoe G, Thompson PM, Kasai K, Hashimoto R; COCORO. Koshiyama D, et al. Among authors: hori t, hashimoto r. Mol Psychiatry. 2020 Apr;25(4):883-895. doi: 10.1038/s41380-019-0553-7. Epub 2019 Nov 29. Mol Psychiatry. 2020. PMID: 31780770 Free PMC article.
In comparison with HCS, we found that schizophrenia, bipolar disorder, and autism spectrum disorder share similar white matter microstructural differences in the body of the corpus callosum; schizophrenia and bipolar disorder featured comparable changes in the limbi …
In comparison with HCS, we found that schizophrenia, bipolar disorder, and autism spectrum disorder share similar white matter micros …
Cognition and interpersonal coordination of patients with schizophrenia who have sports habits.
Fujii K, Yoshihara Y, Matsumoto Y, Tose K, Takeuchi H, Isobe M, Mizuta H, Maniwa D, Okamura T, Murai T, Kawahara Y, Takahashi H. Fujii K, et al. Among authors: isobe m, yoshihara y, murai t, takahashi h. PLoS One. 2020 Nov 9;15(11):e0241863. doi: 10.1371/journal.pone.0241863. eCollection 2020. PLoS One. 2020. PMID: 33166326 Free PMC article.
Team sports activities are effective for improving the negative symptoms and cognitive functions in patients with schizophrenia. However, the interpersonal coordination during the sports and visual cognition of patients with schizophrenia who have team sports habits …
Team sports activities are effective for improving the negative symptoms and cognitive functions in patients with schizophrenia. Howe …
Enhanced carbonyl stress and disrupted white matter integrity in schizophrenia.
Son S, Arai M, Miyata J, Toriumi K, Mizuta H, Hayashi T, Aso T, Itokawa M, Murai T. Son S, et al. Among authors: murai t, miyata j. Schizophr Res. 2020 Sep;223:242-248. doi: 10.1016/j.schres.2020.08.007. Epub 2020 Aug 22. Schizophr Res. 2020. PMID: 32843203
Therefore, we investigated the relationship between carbonyl stress and white matter integrity in schizophrenia using diffusion tensor imaging. A total of 53 patients with schizophrenia and 83 age- and gender-matched healthy controls were recruited. ...There was a s …
Therefore, we investigated the relationship between carbonyl stress and white matter integrity in schizophrenia using diffusion tenso …
Molecular diagnosis of 405 individuals with autism spectrum disorder.
Miyake N, Tsurusaki Y, Fukai R, Kushima I, Okamoto N, Ohashi K, Nakamura K, Hashimoto R, Hiraki Y, Son S, Kato M, Sakai Y, Osaka H, Deguchi K, Matsuishi T, Takeshita S, Fattal-Valevski A, Ekhilevitch N, Tohyama J, Yap P, Keng WT, Kobayashi H, Takubo K, Okada T, Saitoh S, Yasuda Y, Murai T, Nakamura K, Ohga S, Matsumoto A, Inoue K, Saikusa T, Hershkovitz T, Kobayashi Y, Morikawa M, Ito A, Hara T, Uno Y, Seiwa C, Ishizuka K, Shirahata E, Fujita A, Koshimizu E, Miyatake S, Takata A, Mizuguchi T, Ozaki N, Matsumoto N. Miyake N, et al. Among authors: murai t, son s, hashimoto r. Eur J Hum Genet. 2024 Dec;32(12):1551-1558. doi: 10.1038/s41431-023-01335-7. Epub 2023 Mar 27. Eur J Hum Genet. 2024. PMID: 36973392 Free PMC article.
Commonalities and differences in ECT-induced gray matter volume change between depression and schizophrenia.
Kawashima H, Yamasaki S, Kubota M, Hazama M, Fushimi Y, Miyata J, Murai T, Suwa T. Kawashima H, et al. Among authors: murai t, kubota m, miyata j. Neuroimage Clin. 2023;38:103429. doi: 10.1016/j.nicl.2023.103429. Epub 2023 May 3. Neuroimage Clin. 2023. PMID: 37150022 Free PMC article.
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments for depression and schizophrenia, particularly in urgent or treatment-resistant cases. After ECT, regional gray matter volume (GMV) increases have been repeatedly reported both in depressio …
BACKGROUND: Electroconvulsive therapy (ECT) is one of the most effective treatments for depression and schizophrenia, particularly in …
Cortical changes in patients with schizophrenia across two ethnic backgrounds.
Langenbach BP, Kohl W, Murai T, Suslow T, Ohrmann P, Bauer J, Matsukawa N, Son S, Pedersen A, Lichtenstein T, Miyata J, Koelkebeck K. Langenbach BP, et al. Among authors: murai t, son s, miyata j. Sci Rep. 2022 Jun 25;12(1):10810. doi: 10.1038/s41598-022-14914-3. Sci Rep. 2022. PMID: 35752706 Free PMC article.
While it is known that cultural background influences the healthy brain, less is known about how it affects cortical changes in schizophrenia. Here, we tested whether schizophrenia differentially affected the brain in Japanese and German patients. In a sample of 155 …
While it is known that cultural background influences the healthy brain, less is known about how it affects cortical changes in schizophr …
Positron Emission Tomography Assessments of Phosphodiesterase 10A in Patients With Schizophrenia.
Kubota M, Takahata K, Matsuoka K, Sano Y, Yamamoto Y, Tagai K, Tarumi R, Suzuki H, Kurose S, Nakajima S, Shiwaku H, Seki C, Kawamura K, Zhang MR, Takahashi H, Takado Y, Higuchi M. Kubota M, et al. Among authors: takahashi h. Schizophr Bull. 2023 May 3;49(3):688-696. doi: 10.1093/schbul/sbac181. Schizophr Bull. 2023. PMID: 36458958 Free PMC article.
Therapeutic PDE10A inhibition effects on schizophrenia have been reported previously, but the status of this molecule in the living patients with schizophrenia remains elusive. ...CONCLUSIONS: The results suggest altered striatal PDE10A availability and associated l …
Therapeutic PDE10A inhibition effects on schizophrenia have been reported previously, but the status of this molecule in the living p …
Association between enhanced carbonyl stress and decreased apparent axonal density in schizophrenia by multimodal white matter imaging.
Son S, Arai M, Toriumi K, Andica C, Matsuyoshi D, Kamagata K, Aoki S, Kawashima T, Kochiyama T, Okada T, Fushimi Y, Nakamoto Y, Kobayashi Y, Murai T, Itokawa M, Miyata J. Son S, et al. Among authors: murai t, miyata j. Sci Rep. 2023 Jul 27;13(1):12220. doi: 10.1038/s41598-023-39379-w. Sci Rep. 2023. PMID: 37500709 Free PMC article.
We previously reported the relationship between enhanced carbonyl stress and disrupted white matter integrity in schizophrenia, although which microstructural component is disrupted remained unclear. In this study, 32 patients with schizophrenia (SCZ) and 45 age- an …
We previously reported the relationship between enhanced carbonyl stress and disrupted white matter integrity in schizophrenia, altho …
72 results