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Schizophyllum commune induces IL-17-mediated neutrophilic airway inflammation in OVA-induced asthma model mice.
Hanashiro J, Muraosa Y, Toyotome T, Hirose K, Watanabe A, Kamei K. Hanashiro J, et al. Sci Rep. 2019 Dec 18;9(1):19321. doi: 10.1038/s41598-019-55836-x. Sci Rep. 2019. PMID: 31852931 Free PMC article.
We hypothesized that S. commune can exacerbate asthma. To test this hypothesis, we evaluated the direct immunomodulatory activities of S. commune in allergic airway inflammation induced by non-fungal sensitization. ...As S. commune
We hypothesized that S. commune can exacerbate asthma. To test this hypothesis, we evaluated the direct immunomodulator …
The influence of Schizophyllum commune on asthma severity.
Ogawa H, Fujimura M, Takeuchi Y, Makimura K. Ogawa H, et al. Lung. 2011 Dec;189(6):485-92. doi: 10.1007/s00408-011-9320-5. Epub 2011 Oct 18. Lung. 2011. PMID: 22006653
BACKGROUND: The sensitization and exposure to fungal allergens have been reported to be associated with asthma. The aim of this study was to clarify the impact of sensitization to Schizophyllum commune (S. commune) on the severity and exacerbati …
BACKGROUND: The sensitization and exposure to fungal allergens have been reported to be associated with asthma. The aim of this study …
Schizophyllum commune-induced allergic fungal rhinosinusitis and sinobronchial mycosis.
Tsukatani T, Ogawa H, Anzawa K, Kobayashi E, Hasegawa H, Makimura K, Yoshizaki T, Ueda N. Tsukatani T, et al. Med Mycol Case Rep. 2015 Feb 24;8:10-3. doi: 10.1016/j.mmcr.2015.02.004. eCollection 2015 Jun. Med Mycol Case Rep. 2015. PMID: 25756007 Free PMC article.
S. commune-induced AFRS was diagnosed by clinical and radiographic findings, positive specific IgE antibodies against S. commune as measured by the ImmunoCAP system, and sequencing analysis of the fungus. Our two cases with S. commune-ind
S. commune-induced AFRS was diagnosed by clinical and radiographic findings, positive specific IgE antibodies against S
Impact of Schizophyllum sensitization on decline of lung function in asthma.
Ogawa H, Fujimura M, Takeuchi Y, Makimura K. Ogawa H, et al. J Asthma. 2013 Sep;50(7):764-8. doi: 10.3109/02770903.2013.803573. Epub 2013 Jun 18. J Asthma. 2013. PMID: 23725350
This study was performed to determine the correlation between sensitization to Schizophyllum commune and decline of lung function, and to elucidate the outcomes and risk factors, especially from Schizophyllum allergy. ...On multiple regression analysis, the p …
This study was performed to determine the correlation between sensitization to Schizophyllum commune and decline of lung funct …
[Allergic bronchopulmonary mycosis due to Schizophyllum commune and Aspergillus fumigatus].
Ishiguro T, Takayanagi N, Saito A, Akiyama K, Wakayama M, Shibuya K, Shimizu Y, Sugita Y, Kamei K. Ishiguro T, et al. Nihon Kokyuki Gakkai Zasshi. 2011 Aug;49(8):612-8. Nihon Kokyuki Gakkai Zasshi. 2011. PMID: 21894779 Japanese.
A biopsy specimen of a mucus plug obtained by bronchoscopy showed fungal hyphae, eosinophils, and Charcot-Leyden crystals, with evidence of lung tissue eosinophilia. Schizophyllum commune and Aspergillus fumigatus were isolated from his sputum, bronchial washing spe …
A biopsy specimen of a mucus plug obtained by bronchoscopy showed fungal hyphae, eosinophils, and Charcot-Leyden crystals, with evidence of …
Two cases of Schizophyllum asthma: is this a new clinical entity or a precursor of ABPM?
Ogawa H, Fujimura M, Takeuchi Y, Makimura K. Ogawa H, et al. Pulm Pharmacol Ther. 2011 Oct;24(5):559-62. doi: 10.1016/j.pupt.2011.04.030. Epub 2011 Apr 30. Pulm Pharmacol Ther. 2011. PMID: 21549852
BACKGROUND: There is a close link between fungal sensitization and asthma severity. Although Schizophyllum commune (S. commune, "suehirotake" in Japanese), one of the basidiomycetous (BM) fungi, is a fungus that can cause allergic bronchopulmona …
BACKGROUND: There is a close link between fungal sensitization and asthma severity. Although Schizophyllum commune ( …
Characteristics of severe asthma with fungal sensitization.
Masaki K, Fukunaga K, Matsusaka M, Kabata H, Tanosaki T, Mochimaru T, Kamatani T, Ohtsuka K, Baba R, Ueda S, Suzuki Y, Sakamaki F, Oyamada Y, Inoue T, Oguma T, Sayama K, Koh H, Nakamura M, Umeda A, Kamei K, Izuhara K, Asano K, Betsuyaku T. Masaki K, et al. Ann Allergy Asthma Immunol. 2017 Sep;119(3):253-257. doi: 10.1016/j.anai.2017.07.008. Epub 2017 Aug 8. Ann Allergy Asthma Immunol. 2017. PMID: 28801088
BACKGROUND: Some patients with severe asthma also have fungal sensitization and are considered to have severe asthma with fungal sensitization. ...OBJECTIVE: To investigate the clinical characteristics of severe asthma with fungal sensitization. METHODS: The …
BACKGROUND: Some patients with severe asthma also have fungal sensitization and are considered to have severe asthma with fung …
[Allergic bronchopulmonary mycosis induced by Schizophyllum commune--case report and review of the literature].
Amemiya Y, Shirai R, Tokimatsu I, Oka H, Iwata A, Otani S, Umeki K, Sakashita H, Ishii H, Gendo Y, Kishi K, Hiramatsu K, Kadota J. Amemiya Y, et al. Nihon Kokyuki Gakkai Zasshi. 2009 Aug;47(8):692-7. Nihon Kokyuki Gakkai Zasshi. 2009. PMID: 19764511 Review. Japanese.
Laboratory tests showed peripheral eosinophilia, elevated level of serum IgE, and the increased eosinophils in his sputum. Schizophyllum commune was isolated from the bronchoscopically-removed mucous plug. ...However recurrence was recognized on chest CT scan findin …
Laboratory tests showed peripheral eosinophilia, elevated level of serum IgE, and the increased eosinophils in his sputum. Schizophyllum
[Mucoid impaction of the bronchi caused by Schizophyllum commune which developed after discontinuation of itraconazole administration].
Ishiguro T, Takayanagi N, Harasaw K, Yoshii Y, Matsushita A, Yoneda K, Miyahara Y, Kagiyama N, Tokunaga D, Aoki F, Saito H, Ubukata M, Kurashima K, Yanagisawa T, Sugita Y, Kawabata Y, Kamei K. Ishiguro T, et al. Nihon Kokyuki Gakkai Zasshi. 2009 Apr;47(4):296-303. Nihon Kokyuki Gakkai Zasshi. 2009. PMID: 19455959 Review. Japanese.
She improved again after readministration of ITCZ, and MIB has not recurred. This patient was not suffering from asthma and has been well without steroid administration. Reports of respiratory disorders due to S. commune have been increasing, and cases of all …
She improved again after readministration of ITCZ, and MIB has not recurred. This patient was not suffering from asthma and has been …
The Interactions of Airway Bacterial and Fungal Communities in Clinically Stable Asthma.
Liu HY, Li CX, Liang ZY, Zhang SY, Yang WY, Ye YM, Lin YX, Chen RC, Zhou HW, Su J. Liu HY, et al. Front Microbiol. 2020 Jul 21;11:1647. doi: 10.3389/fmicb.2020.01647. eCollection 2020. Front Microbiol. 2020. PMID: 32849339 Free PMC article.
Dysbiotic airway microbiota play important roles in the inflammatory progression of asthma, and exploration of airway microbial interactions further elucidates asthma pathogenesis. ...Correlation networks revealed 3 fungal genera (Schizophyllum, Candida, and …
Dysbiotic airway microbiota play important roles in the inflammatory progression of asthma, and exploration of airway microbial inter …
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