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Page 1
Pharmacological interventions enhance virus-free generation of TRAC-replaced CAR T cells.
Kath J, Du W, Pruene A, Braun T, Thommandru B, Turk R, Sturgeon ML, Kurgan GL, Amini L, Stein M, Zittel T, Martini S, Ostendorf L, Wilhelm A, Akyüz L, Rehm A, Höpken UE, Pruß A, Künkele A, Jacobi AM, Volk HD, Schmueck-Henneresse M, Stripecke R, Reinke P, Wagner DL. Kath J, et al. Among authors: schmueck henneresse m. Mol Ther Methods Clin Dev. 2022 Apr 12;25:311-330. doi: 10.1016/j.omtm.2022.03.018. eCollection 2022 Jun 9. Mol Ther Methods Clin Dev. 2022. PMID: 35573047 Free PMC article.
Integration of ζ-deficient CARs into the CD3ζ gene conveys potent cytotoxicity in T and NK cells.
Kath J, Franke C, Drosdek V, Du W, Glaser V, Fuster-Garcia C, Stein M, Zittel T, Schulenberg S, Porter CE, Andersch L, Künkele A, Alcaniz J, Hoffmann J, Abken H, Abou-El-Enein M, Pruß A, Suzuki M, Cathomen T, Stripecke R, Volk HD, Reinke P, Schmueck-Henneresse M, Wagner DL. Kath J, et al. Among authors: schmueck henneresse m. Blood. 2024 Jun 20;143(25):2599-2611. doi: 10.1182/blood.2023020973. Blood. 2024. PMID: 38493479 Free PMC article.
TGFβ links EBV to multisystem inflammatory syndrome in children.
Goetzke CC, Massoud M, Frischbutter S, Guerra GM, Ferreira-Gomes M, Heinrich F, von Stuckrad ASL, Wisniewski S, Licha JR, Bondareva M, Ehlers L, Khaldi-Plassart S, Javouhey E, Pons S, Trouillet-Assant S, Ozsurekci Y, Zhang Y, Poli MC, Discepolo V, Lo Vecchio A, Sahin B, Verboom M, Hallensleben M, Heuhsen AI, Astudillo C, Espinosa Y, Vial Cox MC, Dobbs K, Delmonte OM, Montealegre Sanchez GA, Magliocco M, Barron K, Danielson J, Petrov L, Unterwalder N, Sawitzki B, Matz M, Lehmann K, Gratopp A, von Bernuth H, Burkhardt LM, Wiese N, Peter L, Schmueck-Henneresse M, Amini L, Maurer M, Roehmel JF, Gewurz BE, Yonker LM, Witkowski M, Kruglov A, Mall MA, Su HC, Ozen S, Radbruch A, Belot A, Durek P, Kallinich T, Mashreghi MF. Goetzke CC, et al. Among authors: schmueck henneresse m. Nature. 2025 Apr;640(8059):762-771. doi: 10.1038/s41586-025-08697-6. Epub 2025 Mar 12. Nature. 2025. PMID: 40074901 Free PMC article.
Progress and harmonization of gene editing to treat human diseases: Proceeding of COST Action CA21113 GenE-HumDi.
Cavazza A, Hendel A, Bak RO, Rio P, Güell M, Lainšček D, Arechavala-Gomeza V, Peng L, Hapil FZ, Harvey J, Ortega FG, Gonzalez-Martinez C, Lederer CW, Mikkelsen K, Gasiunas G, Kalter N, Gonçalves MAFV, Petersen J, Garanto A, Montoliu L, Maresca M, Seemann SE, Gorodkin J, Mazini L, Sanchez R, Rodriguez-Madoz JR, Maldonado-Pérez N, Laura T, Schmueck-Henneresse M, Maccalli C, Grünewald J, Carmona G, Kachamakova-Trojanowska N, Miccio A, Martin F, Turchiano G, Cathomen T, Luo Y, Tsai SQ, Benabdellah K; COST Action CA21113. Cavazza A, et al. Among authors: schmueck henneresse m. Mol Ther Nucleic Acids. 2023 Oct 29;34:102066. doi: 10.1016/j.omtn.2023.102066. eCollection 2023 Dec 12. Mol Ther Nucleic Acids. 2023. PMID: 38034032 Free PMC article. Review.
Effector memory-type regulatory T cells display phenotypic and functional instability.
Wendering DJ, Amini L, Schlickeiser S, Farrera-Sal M, Schulenberg S, Peter L, Mai M, Vollmer T, Du W, Stein M, Hamm F, Malard A, Castro C, Yang M, Ranka R, Rückert T, Durek P, Heinrich F, Gasparoni G, Salhab A, Walter J, Wagner DL, Mashreghi MF, Landwehr-Kenzel S, Polansky JK, Reinke P, Volk HD, Schmueck-Henneresse M. Wendering DJ, et al. Among authors: schmueck henneresse m. Sci Adv. 2024 Sep 6;10(36):eadn3470. doi: 10.1126/sciadv.adn3470. Epub 2024 Sep 4. Sci Adv. 2024. PMID: 39231218 Free PMC article.
Engineering a solution for allogeneic CAR-T rejection.
Amini L, Peter L, Schmueck-Henneresse M. Amini L, et al. Among authors: schmueck henneresse m. Mol Ther. 2024 Oct 2;32(10):3204-3206. doi: 10.1016/j.ymthe.2024.08.025. Epub 2024 Sep 11. Mol Ther. 2024. PMID: 39265578 No abstract available.
Gene editing of CD3 epsilon to redirect regulatory T cells for adoptive T cell transfer.
Du W, Noyan F, McCallion O, Drosdek V, Kath J, Glaser V, Fuster-Garcia C, Yang M, Stein M, Franke C, Pu Y, Weber O, Polansky JK, Cathomen T, Jaeckel E, Hester J, Issa F, Volk HD, Schmueck-Henneresse M, Reinke P, Wagner DL. Du W, et al. Among authors: schmueck henneresse m. Mol Ther. 2025 Mar 5;33(3):997-1013. doi: 10.1016/j.ymthe.2025.01.045. Epub 2025 Feb 3. Mol Ther. 2025. PMID: 39905729 Free PMC article.
35 results