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Anti-3-[(18)F]FACBC positron emission tomography-computerized tomography and (111)In-capromab pendetide single photon emission computerized tomography-computerized tomography for recurrent prostate carcinoma: results of a prospective clinical trial.
Schuster DM, Nieh PT, Jani AB, Amzat R, Bowman FD, Halkar RK, Master VA, Nye JA, Odewole OA, Osunkoya AO, Savir-Baruch B, Alaei-Taleghani P, Goodman MM. Schuster DM, et al. J Urol. 2014 May;191(5):1446-53. doi: 10.1016/j.juro.2013.10.065. Epub 2013 Oct 19. J Urol. 2014. PMID: 24144687 Free PMC article. Clinical Trial.
PURPOSE: We prospectively evaluated the amino acid analogue positron emission tomography radiotracer anti-3-[(18)F]FACBC compared to ProstaScint ((111)In-capromab pendetide) single photon emission computerized tomography-computerized tomography to detect recurrent prost
PURPOSE: We prospectively evaluated the amino acid analogue positron emission tomography radiotracer anti-3-[(18)F]FACBC compared to …
[(14)C]Fluciclovine (alias anti-[(14)C]FACBC) uptake and ASCT2 expression in castration-resistant prostate cancer cells.
Ono M, Oka S, Okudaira H, Nakanishi T, Mizokami A, Kobayashi M, Schuster DM, Goodman MM, Shirakami Y, Kawai K. Ono M, et al. Among authors: schuster dm. Nucl Med Biol. 2015 Nov;42(11):887-92. doi: 10.1016/j.nucmedbio.2015.07.005. Epub 2015 Jul 15. Nucl Med Biol. 2015. PMID: 26278491
INTRODUCTION: trans-1-Amino-3-[(18)F]fluorocyclobutanecarboxylic acid ([(18)F]fluciclovine, also known as anti-[(18)F]FACBC), is a tracer for positron emission tomography (PET) imaging for detection of tumors such as prostate cancer (PCa). Our previous study showed …
INTRODUCTION: trans-1-Amino-3-[(18)F]fluorocyclobutanecarboxylic acid ([(18)F]fluciclovine, also known as anti-[(18)F]FACBC), is a tr …
Differences in transport mechanisms of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid in inflammation, prostate cancer, and glioma cells: comparison with L-[methyl-11C]methionine and 2-deoxy-2-[18F]fluoro-D-glucose.
Oka S, Okudaira H, Ono M, Schuster DM, Goodman MM, Kawai K, Shirakami Y. Oka S, et al. Among authors: schuster dm. Mol Imaging Biol. 2014 Jun;16(3):322-9. doi: 10.1007/s11307-013-0693-0. Mol Imaging Biol. 2014. PMID: 24136390
CONCLUSIONS: The low anti-[(18)F]FACBC accumulation in granulocytes/macrophages may be advantageous in discriminating inflamed regions from tumors. The significant anti-[(18)F]FACBC uptake in T/B cells may cause false-positives in some cancer patients who undergo …
CONCLUSIONS: The low anti-[(18)F]FACBC accumulation in granulocytes/macrophages may be advantageous in discriminating inflamed region …
Imaging of Prostate Cancer Using Fluciclovine.
Savir-Baruch B, Zanoni L, Schuster DM. Savir-Baruch B, et al. Among authors: schuster dm. Urol Clin North Am. 2018 Aug;45(3):489-502. doi: 10.1016/j.ucl.2018.03.015. Epub 2018 Jun 15. Urol Clin North Am. 2018. PMID: 30031468 Review.
Prostate cancer is the most common cancer and the second leading cause of cancer death in men in the United States. ...This review provides a detailed overview of the use of F-18 fluciclovine PET in prostate cancer imaging....
Prostate cancer is the most common cancer and the second leading cause of cancer death in men in the United States. ...This review pr
Imaging of Prostate Cancer Using Fluciclovine.
Savir-Baruch B, Zanoni L, Schuster DM. Savir-Baruch B, et al. Among authors: schuster dm. PET Clin. 2017 Apr;12(2):145-157. doi: 10.1016/j.cpet.2016.11.005. Epub 2017 Jan 23. PET Clin. 2017. PMID: 28267449 Review.
Prostate cancer is the most common cancer and the second leading cause of cancer death in men in the United States. ...Amino acids are building blocks of proteins, and intracellular transport of amino acids is upregulated in prostate cancer. This review provides a d
Prostate cancer is the most common cancer and the second leading cause of cancer death in men in the United States. ...Amino acids ar
Reproducibility and reliability of anti-3-[18F]FACBC uptake measurements in background structures and malignant lesions on follow-up PET-CT in prostate carcinoma: an exploratory analysis.
Odewole OA, Oyenuga OA, Tade F, Savir-Baruch B, Nieh PT, Master V, Chen Z, Wang X, Jani AB, Bellamy LM, Halkar RK, Goodman MM, Schuster DM. Odewole OA, et al. Among authors: schuster dm. Mol Imaging Biol. 2015 Apr;17(2):277-83. doi: 10.1007/s11307-014-0797-1. Mol Imaging Biol. 2015. PMID: 25281411 Free PMC article.
PURPOSE: The aim of this study is to examine the reproducibility of anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F]FACBC) quantitative measurements in key background structures and untreated malignant lesions. PROCEDURES: Retrospective review of 1 …
PURPOSE: The aim of this study is to examine the reproducibility of anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid (anti-3-[(18)F …
Image Guided Planning for Prostate Carcinomas With Incorporation of Anti-3-[18F]FACBC (Fluciclovine) Positron Emission Tomography: Workflow and Initial Findings From a Randomized Trial.
Schreibmann E, Schuster DM, Rossi PJ, Shelton J, Cooper S, Jani AB. Schreibmann E, et al. Among authors: schuster dm. Int J Radiat Oncol Biol Phys. 2016 Sep 1;96(1):206-13. doi: 10.1016/j.ijrobp.2016.04.023. Epub 2016 Apr 30. Int J Radiat Oncol Biol Phys. 2016. PMID: 27511856 Free PMC article. Clinical Trial.
PURPOSE: (18)F-Fluciclovine (anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid) is a novel positron emission tomography (PET)/computed tomography (CT) radiotracer that has demonstrated utility for detection of prostate cancer. Our goal is to report the initial resu …
PURPOSE: (18)F-Fluciclovine (anti-1-amino-3-[(18)F]fluorocyclobutane-1-carboxylic acid) is a novel positron emission tomography (PET)/comput …
PET Tracers Beyond FDG in Prostate Cancer.
Schuster DM, Nanni C, Fanti S. Schuster DM, et al. Semin Nucl Med. 2016 Nov;46(6):507-521. doi: 10.1053/j.semnuclmed.2016.07.005. Epub 2016 Sep 7. Semin Nucl Med. 2016. PMID: 27825431 Free PMC article. Review.
Choline is used for cell membrane synthesis and its metabolism is upregulated in prostate cancer. (11)C-choline and (18)F-choline are in wide clinical use outside the United States, and they have proven most beneficial for detection of recurrent prostate cancer. (11 …
Choline is used for cell membrane synthesis and its metabolism is upregulated in prostate cancer. (11)C-choline and (18)F-choline are …
Kinetic analyses of trans-1-amino-3-[18F]fluorocyclobutanecarboxylic acid transport in Xenopus laevis oocytes expressing human ASCT2 and SNAT2.
Okudaira H, Nakanishi T, Oka S, Kobayashi M, Tamagami H, Schuster DM, Goodman MM, Shirakami Y, Tamai I, Kawai K. Okudaira H, et al. Among authors: schuster dm. Nucl Med Biol. 2013 Jul;40(5):670-5. doi: 10.1016/j.nucmedbio.2013.03.009. Epub 2013 May 3. Nucl Med Biol. 2013. PMID: 23647854
INTRODUCTION: Trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid (anti-[(18)F]FACBC) is a promising amino acid positron emission tomography (PET) radiotracer for visualizing prostate cancer. ...The ASCT2-preferential transport of anti-[(18)F]FACBC in can …
INTRODUCTION: Trans-1-amino-3-[(18)F]fluorocyclobutanecarboxylic acid (anti-[(18)F]FACBC) is a promising amino acid positron emission …
Evaluation of Prostate Cancer with Radiolabeled Amino Acid Analogs.
Schuster DM, Nanni C, Fanti S. Schuster DM, et al. J Nucl Med. 2016 Oct;57(Suppl 3):61S-66S. doi: 10.2967/jnumed.115.170209. J Nucl Med. 2016. PMID: 27694174 Free article. Review.
Conventional imaging of prostate cancer has limitations related to the frequently indolent biology of the disease. ...Radiotracers that are in use or under investigation for targeting salient features of prostate cancer include those directed to glucose, choline, ac …
Conventional imaging of prostate cancer has limitations related to the frequently indolent biology of the disease. ...Radiotracers th …
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