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Anti-proliferative and anti-migratory effects of Scutellaria strigillosa Hemsley extracts against vascular smooth muscle cells.
Li J, Wang H, Shi X, Zhao L, Lv T, Yuan Q, Hao W, Zhu J. Li J, et al. J Ethnopharmacol. 2019 May 10;235:155-163. doi: 10.1016/j.jep.2019.02.016. Epub 2019 Feb 11. J Ethnopharmacol. 2019. PMID: 30763696
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events in the pathogenesis of cardiovascular diseases (CVDs) including restenosis and atherosclerosis. The dried roots of Scutellaria …
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events …
Evaluation of antioxidant activity of extracts from the roots and shoots of Scutellaria alpina L. and S. altissima L. in selected blood cells.
Grzegorczyk-Karolak I, Kontek B, Kontek R, Wysokińska H, Olas B. Grzegorczyk-Karolak I, et al. Adv Clin Exp Med. 2019 Apr;28(4):453-460. doi: 10.17219/acem/78589. Adv Clin Exp Med. 2019. PMID: 30085423 Free article.
BACKGROUND: It is widely known that reactive oxygen species (ROS) can cause oxidative damage in cells and have been linked to the pathogenesis of oxidative diseases, such as atherosclerosis, ischemia, neurodegenerative disease, diabetes, or cancer. ...RESULTS: Extracts (5- …
BACKGROUND: It is widely known that reactive oxygen species (ROS) can cause oxidative damage in cells and have been linked to the pathogenes …
Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review.
Xin L, Gao J, Lin H, Qu Y, Shang C, Wang Y, Lu Y, Cui X. Xin L, et al. Front Pharmacol. 2020 Nov 2;11:583200. doi: 10.3389/fphar.2020.583200. eCollection 2020. Front Pharmacol. 2020. PMID: 33224035 Free PMC article. Review.
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to develop new pharmacotherapies. In eastern countries, traditional Chinese medicine Scutellaria baicalensis Georgi has been used clinically …
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to deve …
Anticoagulant effect of wogonin against tissue factor expression.
Wu YH, Chuang LP, Yu CL, Wang SW, Chen HY, Chang YL. Wu YH, et al. Eur J Pharmacol. 2019 Sep 15;859:172517. doi: 10.1016/j.ejphar.2019.172517. Epub 2019 Jun 29. Eur J Pharmacol. 2019. PMID: 31265843
Tissue factor (TF) is the primary cause of atherothrombosis, the rupture of atherosclerotic plaques with subsequent thrombosis, leading to acute cardiovascular events, such as myocardial infarction and stroke. Wogonin (Wog) is an active component of Scutellaria baicalensis …
Tissue factor (TF) is the primary cause of atherothrombosis, the rupture of atherosclerotic plaques with subsequent thrombosis, leading to a …
Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis.
Fu WJ, Lei T, Yin Z, Pan JH, Chai YS, Xu XY, Yan YX, Wang ZH, Ke J, Wu G, Xu RH, Paranjpe M, Qu L, Nie H. Fu WJ, et al. J Ethnopharmacol. 2017 Jan 4;195:118-126. doi: 10.1016/j.jep.2016.11.015. Epub 2016 Nov 20. J Ethnopharmacol. 2017. PMID: 27880884
OBJECTIVE: The goal of this study was to investigate the anti-atherosclerosis and cardio-protective effects of ANP administration using a rodent model of atherosclerosis induced by a high fat and vitamin D(3). ...The atherosclerotic groups were divided to receive ei …
OBJECTIVE: The goal of this study was to investigate the anti-atherosclerosis and cardio-protective effects of ANP administration usi …
Baicalin alleviates atherosclerosis by relieving oxidative stress and inflammatory responses via inactivating the NF-kappaB and p38 MAPK signaling pathways.
Wu Y, Wang F, Fan L, Zhang W, Wang T, Du Y, Bai X. Wu Y, et al. Biomed Pharmacother. 2018 Jan;97:1673-1679. doi: 10.1016/j.biopha.2017.12.024. Epub 2017 Dec 8. Biomed Pharmacother. 2018. PMID: 29793330
Atherosclerosis (AS) is a chronic progressive disease related to inflammatory reaction. Baicalin is a flavonoid isolated from Scutellaria baicalensis georgi (Huang-qin) and exerts anti-inflammation effects in various diseases. ...
Atherosclerosis (AS) is a chronic progressive disease related to inflammatory reaction. Baicalin is a flavonoid isolated from Scut …
Baicalin and geniposide inhibit the development of atherosclerosis by increasing Wnt1 and inhibiting dickkopf-related protein-1 expression.
Wang B, Liao PP, Liu LH, Fang X, Li W, Guan SM. Wang B, et al. J Geriatr Cardiol. 2016 Oct;13(10):846-854. doi: 10.11909/j.issn.1671-5411.2016.10.013. J Geriatr Cardiol. 2016. PMID: 27928227 Free PMC article.
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin and geniposide could inhibit atherosclerosis …
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoi …
Extracts of Scutellaria baicalensis reduced body weight and blood triglyceride in db/db Mice.
Song KH, Lee SH, Kim BY, Park AY, Kim JY. Song KH, et al. Phytother Res. 2013 Feb;27(2):244-50. doi: 10.1002/ptr.4691. Epub 2012 Apr 25. Phytother Res. 2013. PMID: 22532505
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertension, dysentery, inflammatory diseases, and the common cold. The present study was performed to investigate the anti-obesity and anti-dyslipi …
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertens …
Baicalin and geniposide attenuate atherosclerosis involving lipids regulation and immunoregulation in ApoE-/- mice.
Liao P, Liu L, Wang B, Li W, Fang X, Guan S. Liao P, et al. Eur J Pharmacol. 2014 Oct 5;740:488-95. doi: 10.1016/j.ejphar.2014.06.039. Epub 2014 Jun 30. Eur J Pharmacol. 2014. PMID: 24991786
Baicalin and geniposide, which are respectively isolated from Scutellariae radix and Gardenia jasminoides, have been known to exhibit a number of pharmacological effects, including anti-inflammatory and anti-oxidant. Here, we primarily aimed to observe the protective effec …
Baicalin and geniposide, which are respectively isolated from Scutellariae radix and Gardenia jasminoides, have been known to exhibit …
Baicalin and its aglycone: a novel approach for treatment of metabolic disorders.
Fang P, Yu M, Shi M, Bo P, Gu X, Zhang Z. Fang P, et al. Pharmacol Rep. 2020 Feb;72(1):13-23. doi: 10.1007/s43440-019-00024-x. Epub 2020 Jan 8. Pharmacol Rep. 2020. PMID: 32016847
Therefore, novel ways to prevent insulin resistance and type 2 diabetes are urgently needed. The roots of Scutellaria radix are commonly used in traditional Chinese medicines for prevention and treatment of type 2 diabetes, atherosclerosis, hypertension, hyperlipide …
Therefore, novel ways to prevent insulin resistance and type 2 diabetes are urgently needed. The roots of Scutellaria radix are commo …
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