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1994 1
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2019 4
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31 results

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Page 1
Identification of bioactive compounds and potential mechanisms of scutellariae radix-coptidis rhizoma in the treatment of atherosclerosis by integrating network pharmacology and experimental validation.
Ji L, Song T, Ge C, Wu Q, Ma L, Chen X, Chen T, Chen Q, Chen Z, Chen W. Ji L, et al. Biomed Pharmacother. 2023 Sep;165:115210. doi: 10.1016/j.biopha.2023.115210. Epub 2023 Jul 25. Biomed Pharmacother. 2023. PMID: 37499457 Free article.
OBJECTIVE: This study aims at investigating the potential targets and functional mechanisms of Scutellariae Radix-Coptidis Rhizoma (QLYD) against atherosclerosis (AS) through network pharmacology, molecular docking, bioinformatic analysis and experimental validation …
OBJECTIVE: This study aims at investigating the potential targets and functional mechanisms of Scutellariae Radix-Coptidis Rhizoma (Q …
Unraveling the Role of Scutellaria baicalensis for the Treatment of Breast Cancer Using Network Pharmacology, Molecular Docking, and Molecular Dynamics Simulation.
Jiao Y, Shi C, Sun Y. Jiao Y, et al. Int J Mol Sci. 2023 Feb 10;24(4):3594. doi: 10.3390/ijms24043594. Int J Mol Sci. 2023. PMID: 36835006 Free PMC article.
Scutellaria baicalensis is often used to treat breast cancer, but the molecular mechanism behind the action is unclear. In this study, network pharmacology, molecular docking, and molecular dynamics simulation are combined to reveal the most active compound in Scutellar
Scutellaria baicalensis is often used to treat breast cancer, but the molecular mechanism behind the action is unclear. In this study
Promising influences of Scutellaria baicalensis and its two active constituents, baicalin, and baicalein, against metabolic syndrome: A review.
Baradaran Rahimi V, Askari VR, Hosseinzadeh H. Baradaran Rahimi V, et al. Phytother Res. 2021 Jul;35(7):3558-3574. doi: 10.1002/ptr.7046. Epub 2021 Feb 16. Phytother Res. 2021. PMID: 33590943 Review.
Metabolic syndrome is known as a group of metabolic abnormalities with features including central obesity, insulin resistance, hypercholesterolemia, hypertriglyceridemia, and hypertension as well as low level of high-density lipoprotein (HDL)-cholesterol. Previous studies showed …
Metabolic syndrome is known as a group of metabolic abnormalities with features including central obesity, insulin resistance, hypercholeste …
Banxia Xiexin decoction alleviates AS co-depression disease by regulating the gut microbiome-lipid metabolic axis.
Liao XX, Hu K, Xie XH, Wen YL, Wang R, Hu ZW, Zhou YL, Li JJ, Wu MK, Yu JX, Chen JW, Ren P, Wu XY, Zhou JJ. Liao XX, et al. J Ethnopharmacol. 2023 Sep 15;313:116468. doi: 10.1016/j.jep.2023.116468. Epub 2023 Apr 10. J Ethnopharmacol. 2023. PMID: 37044233 Free article.
ETHNOPHARMACOLOGICAL RELEVANCE: Banxia Xiexin decoction (BXD) is a classic Chinese herbal formulation consisting of 7 herbs including Pinelliae Rhizoma, Scutellariae Radix, Zingiberis Rhizoma, Ginseng Radix, Glycyrrhizae Radix, Coptidis Rhizoma, and Jujubae Fructus, which …
ETHNOPHARMACOLOGICAL RELEVANCE: Banxia Xiexin decoction (BXD) is a classic Chinese herbal formulation consisting of 7 herbs including Pinell …
Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review.
Xin L, Gao J, Lin H, Qu Y, Shang C, Wang Y, Lu Y, Cui X. Xin L, et al. Front Pharmacol. 2020 Nov 2;11:583200. doi: 10.3389/fphar.2020.583200. eCollection 2020. Front Pharmacol. 2020. PMID: 33224035 Free PMC article. Review.
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to develop new pharmacotherapies. In eastern countries, traditional Chinese medicine Scutellaria baicalensis Georgi has been used clinically …
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to deve …
Anti-proliferative and anti-migratory effects of Scutellaria strigillosa Hemsley extracts against vascular smooth muscle cells.
Li J, Wang H, Shi X, Zhao L, Lv T, Yuan Q, Hao W, Zhu J. Li J, et al. J Ethnopharmacol. 2019 May 10;235:155-163. doi: 10.1016/j.jep.2019.02.016. Epub 2019 Feb 11. J Ethnopharmacol. 2019. PMID: 30763696
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events in the pathogenesis of cardiovascular diseases (CVDs) including restenosis and atherosclerosis. The dried roots of Scutellaria
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events …
Neuraminidase 1 and its Inhibitors from Chinese Herbal Medicines: An Emerging Role for Cardiovascular Diseases.
Zhang JY, Chen QQ, Li J, Zhang L, Qi LW. Zhang JY, et al. Am J Chin Med. 2021;49(4):843-862. doi: 10.1142/S0192415X21500403. Epub 2021 Apr 6. Am J Chin Med. 2021. PMID: 33827385 Review.
In this review, we center the attention to the role of Neu1 in cardiovascular diseases, including atherosclerosis, ischemic myocardial injury, cerebrovascular disease, congenital heart disease, and pulmonary embolism. ...Many Chinese herbs and Chinese herb preparations, su …
In this review, we center the attention to the role of Neu1 in cardiovascular diseases, including atherosclerosis, ischemic myocardia …
Baicalin and geniposide inhibit the development of atherosclerosis by increasing Wnt1 and inhibiting dickkopf-related protein-1 expression.
Wang B, Liao PP, Liu LH, Fang X, Li W, Guan SM. Wang B, et al. J Geriatr Cardiol. 2016 Oct;13(10):846-854. doi: 10.11909/j.issn.1671-5411.2016.10.013. J Geriatr Cardiol. 2016. PMID: 27928227 Free PMC article.
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin and geniposide could inhibit atherosclerosis
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoi …
Anticoagulant effect of wogonin against tissue factor expression.
Wu YH, Chuang LP, Yu CL, Wang SW, Chen HY, Chang YL. Wu YH, et al. Eur J Pharmacol. 2019 Sep 15;859:172517. doi: 10.1016/j.ejphar.2019.172517. Epub 2019 Jun 29. Eur J Pharmacol. 2019. PMID: 31265843
Tissue factor (TF) is the primary cause of atherothrombosis, the rupture of atherosclerotic plaques with subsequent thrombosis, leading to acute cardiovascular events, such as myocardial infarction and stroke. Wogonin (Wog) is an active component of Scutellaria baicalensis …
Tissue factor (TF) is the primary cause of atherothrombosis, the rupture of atherosclerotic plaques with subsequent thrombosis, leading to a …
Extracts of Scutellaria baicalensis reduced body weight and blood triglyceride in db/db Mice.
Song KH, Lee SH, Kim BY, Park AY, Kim JY. Song KH, et al. Phytother Res. 2013 Feb;27(2):244-50. doi: 10.1002/ptr.4691. Epub 2012 Apr 25. Phytother Res. 2013. PMID: 22532505
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertension, dysentery, inflammatory diseases, and the common cold. The present study was performed to investigate the anti-obesity and anti-dyslipi
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertens
31 results