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Promising influences of Scutellaria baicalensis and its two active constituents, baicalin, and baicalein, against metabolic syndrome: A review.
Baradaran Rahimi V, Askari VR, Hosseinzadeh H. Baradaran Rahimi V, et al. Phytother Res. 2021 Jul;35(7):3558-3574. doi: 10.1002/ptr.7046. Epub 2021 Feb 16. Phytother Res. 2021. PMID: 33590943 Review.
Metabolic syndrome is known as a group of metabolic abnormalities with features including central obesity, insulin resistance, hypercholesterolemia, hypertriglyceridemia, and hypertension as well as low level of high-density lipoprotein (HDL)-cholesterol. Previous studies showed …
Metabolic syndrome is known as a group of metabolic abnormalities with features including central obesity, insulin resistance, hypercholeste …
Regulatory Mechanisms of Baicalin in Cardiovascular Diseases: A Review.
Xin L, Gao J, Lin H, Qu Y, Shang C, Wang Y, Lu Y, Cui X. Xin L, et al. Front Pharmacol. 2020 Nov 2;11:583200. doi: 10.3389/fphar.2020.583200. eCollection 2020. Front Pharmacol. 2020. PMID: 33224035 Free PMC article. Review.
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to develop new pharmacotherapies. In eastern countries, traditional Chinese medicine Scutellaria baicalensis Georgi has been used clinically …
Cardiovascular diseases (CVDs) is the leading cause of high morbidity and mortality worldwide, which emphasizes the urgent necessity to deve …
Neuraminidase 1 and its Inhibitors from Chinese Herbal Medicines: An Emerging Role for Cardiovascular Diseases.
Zhang JY, Chen QQ, Li J, Zhang L, Qi LW. Zhang JY, et al. Am J Chin Med. 2021;49(4):843-862. doi: 10.1142/S0192415X21500403. Epub 2021 Apr 6. Am J Chin Med. 2021. PMID: 33827385 Review.
In this review, we center the attention to the role of Neu1 in cardiovascular diseases, including atherosclerosis, ischemic myocardial injury, cerebrovascular disease, congenital heart disease, and pulmonary embolism. ...Many Chinese herbs and Chinese herb preparations, su …
In this review, we center the attention to the role of Neu1 in cardiovascular diseases, including atherosclerosis, ischemic myocardia …
Anti-proliferative and anti-migratory effects of Scutellaria strigillosa Hemsley extracts against vascular smooth muscle cells.
Li J, Wang H, Shi X, Zhao L, Lv T, Yuan Q, Hao W, Zhu J. Li J, et al. J Ethnopharmacol. 2019 May 10;235:155-163. doi: 10.1016/j.jep.2019.02.016. Epub 2019 Feb 11. J Ethnopharmacol. 2019. PMID: 30763696
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events in the pathogenesis of cardiovascular diseases (CVDs) including restenosis and atherosclerosis. The dried roots of Scutellaria
ETHNOPHARMACOLOGICAL RELEVANCE: The abnormal increase in vascular smooth muscle cell (VSMC) proliferation and migration are critical events …
Arginase II inhibitory activity of flavonoid compounds from Scutellaria indica.
Kim SW, Cuong TD, Hung TM, Ryoo S, Lee JH, Min BS. Kim SW, et al. Arch Pharm Res. 2013 Aug;36(8):922-6. doi: 10.1007/s12272-013-0125-3. Epub 2013 Apr 20. Arch Pharm Res. 2013. PMID: 23604721 Free PMC article.
Arginase II has recently reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. In the course of screening plants used in natural medicines as arginase II inhibitory activity, a methanol extract of Scutellaria in …
Arginase II has recently reported as a novel therapeutic target for the treatment of cardiovascular diseases such as atherosclerosis. …
Extracts of Scutellaria baicalensis reduced body weight and blood triglyceride in db/db Mice.
Song KH, Lee SH, Kim BY, Park AY, Kim JY. Song KH, et al. Phytother Res. 2013 Feb;27(2):244-50. doi: 10.1002/ptr.4691. Epub 2012 Apr 25. Phytother Res. 2013. PMID: 22532505
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertension, dysentery, inflammatory diseases, and the common cold. The present study was performed to investigate the anti-obesity and anti-dyslipi
Scutellaria baicalensis has been extensively employed for the clinical treatment of hyperlipidemia, atherosclerosis, hypertens
Baicalin and geniposide inhibit the development of atherosclerosis by increasing Wnt1 and inhibiting dickkopf-related protein-1 expression.
Wang B, Liao PP, Liu LH, Fang X, Li W, Guan SM. Wang B, et al. J Geriatr Cardiol. 2016 Oct;13(10):846-854. doi: 10.11909/j.issn.1671-5411.2016.10.013. J Geriatr Cardiol. 2016. PMID: 27928227 Free PMC article.
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoids ellis inhibited atherosclerosis. In this study, we sought to determine if baicalin and geniposide could inhibit atherosclerosis
BACKGROUND: Our previous study showed that the combined Chinese herbs containing scutellaria baicalensis georgi and gardenia jasminoi …
Anti-atherosclerosis and cardio-protective effects of the Angong Niuhuang Pill on a high fat and vitamin D3 induced rodent model of atherosclerosis.
Fu WJ, Lei T, Yin Z, Pan JH, Chai YS, Xu XY, Yan YX, Wang ZH, Ke J, Wu G, Xu RH, Paranjpe M, Qu L, Nie H. Fu WJ, et al. J Ethnopharmacol. 2017 Jan 4;195:118-126. doi: 10.1016/j.jep.2016.11.015. Epub 2016 Nov 20. J Ethnopharmacol. 2017. PMID: 27880884
OBJECTIVE: The goal of this study was to investigate the anti-atherosclerosis and cardio-protective effects of ANP administration using a rodent model of atherosclerosis induced by a high fat and vitamin D(3). ...The atherosclerotic groups were divided to receive ei …
OBJECTIVE: The goal of this study was to investigate the anti-atherosclerosis and cardio-protective effects of ANP administration usi …
Baicalin and geniposide attenuate atherosclerosis involving lipids regulation and immunoregulation in ApoE-/- mice.
Liao P, Liu L, Wang B, Li W, Fang X, Guan S. Liao P, et al. Eur J Pharmacol. 2014 Oct 5;740:488-95. doi: 10.1016/j.ejphar.2014.06.039. Epub 2014 Jun 30. Eur J Pharmacol. 2014. PMID: 24991786
Baicalin and geniposide, which are respectively isolated from Scutellariae radix and Gardenia jasminoides, have been known to exhibit a number of pharmacological effects, including anti-inflammatory and anti-oxidant. Here, we primarily aimed to observe the protective effec …
Baicalin and geniposide, which are respectively isolated from Scutellariae radix and Gardenia jasminoides, have been known to exhibit …
Baicalin alleviates atherosclerosis by relieving oxidative stress and inflammatory responses via inactivating the NF-κB and p38 MAPK signaling pathways.
Wu Y, Wang F, Fan L, Zhang W, Wang T, Du Y, Bai X. Wu Y, et al. Biomed Pharmacother. 2018 Jan;97:1673-1679. doi: 10.1016/j.biopha.2017.12.024. Epub 2017 Dec 8. Biomed Pharmacother. 2018. PMID: 29793330
Atherosclerosis (AS) is a chronic progressive disease related to inflammatory reaction. Baicalin is a flavonoid isolated from Scutellaria baicalensis georgi (Huang-qin) and exerts anti-inflammation effects in various diseases. ...
Atherosclerosis (AS) is a chronic progressive disease related to inflammatory reaction. Baicalin is a flavonoid isolated from Scut
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