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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1980 1
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1988 11
1989 18
1990 25
1991 17
1992 14
1993 19
1994 10
1995 14
1996 17
1997 14
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1999 22
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2002 41
2003 76
2004 79
2005 94
2006 108
2007 101
2008 95
2009 95
2010 94
2011 88
2012 56
2013 73
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1,610 results

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Page 1
Allergic Rhinitis.
Cohen B. Cohen B. Pediatr Rev. 2023 Oct 1;44(10):537-550. doi: 10.1542/pir.2022-005618. Pediatr Rev. 2023. PMID: 37777655
Pharmacotherapy of AR has expanded, with many intranasal corticosteroids, intranasal antihistamines, and second-generation oral antihistamines approved for pediatric use. Allergen immunotherapy, including both subcutaneous and sublingual forms, are app …
Pharmacotherapy of AR has expanded, with many intranasal corticosteroids, intranasal antihistamines, and second-generation …
Comparative Efficacy and Acceptability of Licensed Dose Second-Generation Antihistamines in Chronic Spontaneous Urticaria: A Network Meta-Analysis.
Phinyo P, Koompawichit P, Nochaiwong S, Tovanabutra N, Chiewchanvit S, Chuamanochan M. Phinyo P, et al. J Allergy Clin Immunol Pract. 2021 Feb;9(2):956-970.e57. doi: 10.1016/j.jaip.2020.08.055. Epub 2020 Sep 8. J Allergy Clin Immunol Pract. 2021. PMID: 32916325
BACKGROUND: Licensed dose second-generation H1-antihistamines (sgAHs) are the first-line treatment in chronic spontaneous urticaria (CSU). ...
BACKGROUND: Licensed dose second-generation H1-antihistamines (sgAHs) are the first-line treatment in chronic sp …
Sedation and performance impairment of diphenhydramine and second-generation antihistamines: a meta-analysis.
Bender BG, Berning S, Dudden R, Milgrom H, Tran ZV. Bender BG, et al. J Allergy Clin Immunol. 2003 Apr;111(4):770-6. doi: 10.1067/mai.2003.1408. J Allergy Clin Immunol. 2003. PMID: 12704356
BACKGROUND: Antihistamines are among the most frequently used medications in the United States. Despite dramatically higher cost, second-generation antihistamines are replacing diphenhydramine because of the perception that they are not constrained by …
BACKGROUND: Antihistamines are among the most frequently used medications in the United States. Despite dramatically higher cost, …
Antihistamines: ABC for the pediatricians.
Parisi GF, Licari A, Papale M, Manti S, Salpietro C, Marseglia GL, Leonardi S. Parisi GF, et al. Pediatr Allergy Immunol. 2020 Feb;31 Suppl 24:34-36. doi: 10.1111/pai.13152. Pediatr Allergy Immunol. 2020. PMID: 32017222
Antihistamines are currently one of the most commonly administered drugs in children. They are used to treat symptoms that depend on histamine release, namely allergic diseases, such as rhinitis, asthma, urticaria, and anaphylaxis. It is possible to distinguish firs …
Antihistamines are currently one of the most commonly administered drugs in children. They are used to treat symptoms that depend on …
Antihistamines for Allergic Rhinitis Treatment from the Viewpoint of Nonsedative Properties.
Kawauchi H, Yanai K, Wang DY, Itahashi K, Okubo K. Kawauchi H, et al. Int J Mol Sci. 2019 Jan 8;20(1):213. doi: 10.3390/ijms20010213. Int J Mol Sci. 2019. PMID: 30626077 Free PMC article. Review.
Antihistamines are classified into non-sedating (<20%), less-sedating (20-50%), and sedating (50%) groups based on H1RO. Among the non-sedating group, fexofenadine and bilastine are classified into "non-brain-penetrating anti …
Antihistamines are classified into non-sedating (<20%), less-sedating (20-50%), and sedating (50%) gro …
Second generation antihistamines: an update.
Sánchez-Borges M, Ansotegui IJ. Sánchez-Borges M, et al. Curr Opin Allergy Clin Immunol. 2019 Aug;19(4):358-364. doi: 10.1097/ACI.0000000000000556. Curr Opin Allergy Clin Immunol. 2019. PMID: 31169593 Review.
PURPOSE OF REVIEW: This article presents an update on the clinical pharmacology, mechanisms of action, and safety of second generation antihistamines (SGAHs). RECENT FINDINGS: Recent research has shown the efficacy and good tolerance of SGAHs supporting its i …
PURPOSE OF REVIEW: This article presents an update on the clinical pharmacology, mechanisms of action, and safety of second genera …
Second-generation antihistamines: a study of poisoning in children.
Verdu E, Blanc-Brisset I, Meyer G, Le Roux G, Bruneau C, Deguigne M. Verdu E, et al. Clin Toxicol (Phila). 2020 Apr;58(4):275-283. doi: 10.1080/15563650.2019.1634812. Epub 2019 Jul 4. Clin Toxicol (Phila). 2020. PMID: 31271318
Background and objectives: The toxicity of second-generation antihistamines after an overdose by a child is still unknown. The objective of this study is to use data from Poisons Centres in France to describe the toxicity profile of second-generatio …
Background and objectives: The toxicity of second-generation antihistamines after an overdose by a child is still unkno …
Why fexofenadine is considered as a truly non-sedating antihistamine with no brain penetration: a systematic review.
Ansotegui IJ, Bousquet J, Canonica GW, Demoly P, Gómez RM, Meltzer EO, Murrieta-Aguttes M, Naclerio RM, Rosario Filho N, Scadding GK. Ansotegui IJ, et al. Curr Med Res Opin. 2024 Aug;40(8):1297-1309. doi: 10.1080/03007995.2024.2378172. Epub 2024 Jul 19. Curr Med Res Opin. 2024. PMID: 39028636 Free article.
OBJECTIVE: Fexofenadine is a second-generation inverse agonist of H(1)-receptor of histamine which is highly selective with proven efficacy in relieving symptoms associated with allergic conditions. ...CONCLUSION: Published literature based on various paramet …
OBJECTIVE: Fexofenadine is a second-generation inverse agonist of H(1)-receptor of histamine which is highly selective …
Clinical pharmacokinetics and pharmacodynamics of desloratadine, fexofenadine and levocetirizine : a comparative review.
Devillier P, Roche N, Faisy C. Devillier P, et al. Clin Pharmacokinet. 2008;47(4):217-30. doi: 10.2165/00003088-200847040-00001. Clin Pharmacokinet. 2008. PMID: 18336052 Review.
Second-generation histamine H(1) receptor antagonists were developed to provide efficacious treatment of allergic rhinitis (AR) and chronic idiopathic urticaria (CIU) while decreasing adverse effects associated with first-generation agents. When …
Second-generation histamine H(1) receptor antagonists were developed to provide efficacious treatment of allergi …
Antihistamines.
Armstrong SC, Cozza KL. Armstrong SC, et al. Psychosomatics. 2003 Sep-Oct;44(5):430-4. doi: 10.1176/appi.psy.44.5.430. Psychosomatics. 2003. PMID: 12954920 Review.
Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamines is coming to light through in vivo and in vitro studies. The polymorphic CYP 2D6 metabolic enzyme appears to be potently inhibited by …
Antihistamines and their drug-drug interactions are reviewed in depth. The metabolism of "classic" or sedating antihistamin …
1,610 results