Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation

Search Page

Filters

My Custom Filters

Edit custom filters

Results by year

Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1946 2
1947 1
1951 2
1953 1
1955 3
1956 7
1957 6
1958 7
1959 4
1960 5
1961 12
1962 10
1963 16
1964 7
1965 11
1966 8
1967 6
1968 9
1969 34
1970 107
1971 252
1972 306
1973 309
1974 226
1975 242
1976 268
1977 250
1978 243
1979 257
1980 298
1981 272
1982 266
1983 309
1984 269
1985 290
1986 279
1987 340
1988 345
1989 380
1990 354
1991 367
1992 379
1993 430
1994 419
1995 429
1996 462
1997 408
1998 483
1999 489
2000 531
2001 589
2002 615
2003 605
2004 602
2005 617
2006 699
2007 665
2008 685
2009 660
2010 679
2011 633
2012 680
2013 623
2014 619
2015 645
2016 568
2017 569
2018 523
2019 508
2020 534
2021 570
2022 475
2023 465
2024 448
2025 478
2026 293

Publication date

Text availability

Article attribute

Article type

Additional filters

Article Language

Species

Sex

Age

Other

Search Results

23,994 results

Results by year

Filters applied: . Clear all
Page 1
Secretory granule exocytosis.
Burgoyne RD, Morgan A. Burgoyne RD, et al. Physiol Rev. 2003 Apr;83(2):581-632. doi: 10.1152/physrev.00031.2002. Physiol Rev. 2003. PMID: 12663867 Free article. Review.
Secretory granule exocytosis occurs through mechanisms with many aspects in common with synaptic vesicle exocytosis and most likely uses the same basic protein components. ...In this review we describe the wide range of cell types in which regulated secretory …
Secretory granule exocytosis occurs through mechanisms with many aspects in common with synaptic vesicle exocytosis and most l …
Rediscovering the intricacies of secretory granule biogenesis.
Campelo F, Tian M, von Blume J. Campelo F, et al. Curr Opin Cell Biol. 2023 Dec;85:102231. doi: 10.1016/j.ceb.2023.102231. Epub 2023 Aug 30. Curr Opin Cell Biol. 2023. PMID: 37657367 Review.
Regulated secretion, an essential cellular process, relies on secretory granules (SGs) for the controlled release of a diverse range of cargo molecules, including proteins, peptides, hormones, enzymes, and neurotransmitters. ...Research in the last three decades has reveal …
Regulated secretion, an essential cellular process, relies on secretory granules (SGs) for the controlled release of a diverse range …
Revisiting secretory granule fusion at vesicular pseudopodia.
Scher N, Avinoam O. Scher N, et al. J Cell Sci. 2025 Sep 1;138(17):jcs263980. doi: 10.1242/jcs.263980. Epub 2025 Sep 3. J Cell Sci. 2025. PMID: 40899476 Review.
Secretory granules are specialized vesicles that package large amounts of cargo, such as hormones, enzymes and mucous. They are typically stored intracellularly until an extracellular signal initiates exocytosis, characterized by fusion between the secretory …
Secretory granules are specialized vesicles that package large amounts of cargo, such as hormones, enzymes and mucous. They ar …
Biogenesis of the Insulin Secretory Granule in Health and Disease.
Guest PC. Guest PC. Adv Exp Med Biol. 2019;1134:17-32. doi: 10.1007/978-3-030-12668-1_2. Adv Exp Med Biol. 2019. PMID: 30919330 Review.
The secretory granules of pancreatic beta cells are specialized organelles responsible for the packaging, storage and secretion of the vital hormone insulin. ...This chapter discusses the various processes involved in insulin granule biogenesis with a focus on the …
The secretory granules of pancreatic beta cells are specialized organelles responsible for the packaging, storage and secretion of th …
Secretory granule biogenesis: rafting to the SNARE.
Tooze SA, Martens GJ, Huttner WB. Tooze SA, et al. Trends Cell Biol. 2001 Mar;11(3):116-22. doi: 10.1016/s0962-8924(00)01907-3. Trends Cell Biol. 2001. PMID: 11306272 Review.
The formation of a mature secretory granule (MSG) involves a series of discrete and unique events such as protein sorting, formation of immature secretory granules (ISGs), prohormone processing and vesicle fusion. ...At the heart of these findings is the eluc …
The formation of a mature secretory granule (MSG) involves a series of discrete and unique events such as protein sorting, for …
Dense-core secretory granule biogenesis.
Kim T, Gondré-Lewis MC, Arnaoutova I, Loh YP. Kim T, et al. Physiology (Bethesda). 2006 Apr;21:124-33. doi: 10.1152/physiol.00043.2005. Physiology (Bethesda). 2006. PMID: 16565478 Free article. Review.
The dense-core secretory granule is a key organelle for secretion of hormones and neuropeptides in endocrine cells and neurons, in response to stimulation. ...
The dense-core secretory granule is a key organelle for secretion of hormones and neuropeptides in endocrine cells and neurons …
Secretory granule and synaptic vesicle formation.
Kelly RB. Kelly RB. Curr Opin Cell Biol. 1991 Aug;3(4):654-60. doi: 10.1016/0955-0674(91)90037-y. Curr Opin Cell Biol. 1991. PMID: 1663373 Review.
Sorting of secreted proteins into dense-core secretory granules may involve selective aggregation of regulated secretory proteins, rather than a conventional sortase. Synaptic vesicles, which mediate paracrine communication between adjacent cells, appear to a …
Sorting of secreted proteins into dense-core secretory granules may involve selective aggregation of regulated secretory prote …
Mast cell secretory granule fusion with amphisomes coordinates their homotypic fusion and release of exosomes.
Omari S, Roded A, Eisenberg M, Ali H, Fukuda M, Galli SJ, Sagi-Eisenberg R. Omari S, et al. Cell Rep. 2024 Jul 23;43(7):114482. doi: 10.1016/j.celrep.2024.114482. Epub 2024 Jul 9. Cell Rep. 2024. PMID: 38985670 Free article.
Secretory granule (SG) fusion is an intermediate step in SG biogenesis. However, the precise mechanism of this process is not completely understood. ...
Secretory granule (SG) fusion is an intermediate step in SG biogenesis. However, the precise mechanism of this process is not …
The insulin secretory granule is a hotspot for autoantigen formation in type 1 diabetes.
Groegler J, Callebaut A, James EA, Delong T. Groegler J, et al. Diabetologia. 2024 Aug;67(8):1507-1516. doi: 10.1007/s00125-024-06164-x. Epub 2024 May 29. Diabetologia. 2024. PMID: 38811417 Review.
Furthermore, autoantibody prevalence data and murine studies implicate insulin as a crucial autoantigen for the disease. Studies identify secretory granules, where proinsulin is processed into mature insulin, stored and released in response to glucose stimulation, as a sou …
Furthermore, autoantibody prevalence data and murine studies implicate insulin as a crucial autoantigen for the disease. Studies identify …
Signaling from the secretory granule to the nucleus.
Rajagopal C, Mains RE, Eipper BA. Rajagopal C, et al. Crit Rev Biochem Mol Biol. 2012 Jul-Aug;47(4):391-406. doi: 10.3109/10409238.2012.694845. Epub 2012 Jun 8. Crit Rev Biochem Mol Biol. 2012. PMID: 22681236 Free PMC article. Review.
The larger granules that contain bioactive peptides present the secretory cell with special challenges, as the peptide precursors are inserted into the lumen of the secretory pathway in the cell soma and undergo biosynthetic processing while being transported to dis …
The larger granules that contain bioactive peptides present the secretory cell with special challenges, as the peptide precursors are …
23,994 results
You have reached the last available page of results. Please see the User Guide for more information.