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Page 1
Targeted therapies for uveitis in spondyloarthritis: A narrative review.
Jacquot R, Kodjikian L, Chapurlat R, Sève P. Jacquot R, et al. Joint Bone Spine. 2024 Sep;91(5):105697. doi: 10.1016/j.jbspin.2024.105697. Epub 2024 Feb 1. Joint Bone Spine. 2024. PMID: 38309516 Free article. Review.
Ophthalmologists will describe an acute anterior unilateral uveitis. Most patients present with episodic acute anterior non-granulomatous uveitis and retain excellent visual acuity. ...Significant benefits have been obtained with the tumor necrosis factor-alpha inhi …
Ophthalmologists will describe an acute anterior unilateral uveitis. Most patients present with episodic acute anterior non-granuloma …
New-Onset Uveitis Possibly Caused by Secukinumab in a 47-Year-Old Male Patient with Long-Standing Ankylosing Spondylitis.
Nadwi H, Janaini M, Zammo M, Cheikh M, Almoallim H. Nadwi H, et al. Int Med Case Rep J. 2020 Aug 5;13:331-334. doi: 10.2147/IMCRJ.S265812. eCollection 2020. Int Med Case Rep J. 2020. PMID: 32801946 Free PMC article.
Although it has been proven that certain agents are linked with a paradoxical increase in uveitis, there are limited data on whether secukinumab has this effect or not. We report a case of a new-onset anterior uveitis after 6 months of starting secu …
Although it has been proven that certain agents are linked with a paradoxical increase in uveitis, there are limited data on w …
Behcet's-like disease during secukinumab treatment: new paradoxical reaction?
Calleja Algarra A, Aragón Miguel R, Andrés Lencina JJ, Pinilla Martín B, Vico Alonso C, Rodríguez Peralto JL, Ortiz Romero PL, Rivera Díaz R. Calleja Algarra A, et al. J Dtsch Dermatol Ges. 2021 Jan;19(1):116-118. doi: 10.1111/ddg.14196. Epub 2020 Aug 10. J Dtsch Dermatol Ges. 2021. PMID: 32776677 No abstract available.
Paradoxical Reactions: Anti-Tumor Necrosis Factor Alpha Agents, Ustekinumab, Secukinumab, Ixekizumab, and Others.
Puig L. Puig L. Curr Probl Dermatol. 2018;53:49-63. doi: 10.1159/000479475. Epub 2017 Nov 7. Curr Probl Dermatol. 2018. PMID: 29131037
Paradoxical reactions have subsequently been reported with other biological drugs or classes (e.g., tocilizumab), even though in some cases insufficient efficacy or phenotype switch may be difficult to differentiate from true paradoxical reactions. This chapter will …
Paradoxical reactions have subsequently been reported with other biological drugs or classes (e.g., tocilizumab), even though in some …
Acute Posterior Multifocal Placoid Pigment Epitheliopathy: A Rare Presentation of Anklylosing Spondylitis or a Paradoxical Reaction to Secukinumab?
Altinisik M, Delibay Y, Erdogan M. Altinisik M, et al. Ocul Immunol Inflamm. 2024 Jan;32(1):120-122. doi: 10.1080/09273948.2022.2150225. Epub 2023 Jan 6. Ocul Immunol Inflamm. 2024. PMID: 36608284
PURPOSE: To describe an atypical presentation of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in a patient with ankylosing spondylitis (AS) receiving secukinumab. METHODS: Retrospective chart review. RESULTS: A 48-year-old female patient with AS recei …
PURPOSE: To describe an atypical presentation of acute posterior multifocal placoid pigment epitheliopathy (APMPPE) in a patient with ankylo …
What are the characteristics of paradoxical effects in the Biotherapies Registry of the Moroccan Society of Rheumatology?
Taoubane L, Maghraoui AE, Niamane R, Hmamouchi I, Allali F, Bahiri R, Mkinsi O, Hassikou H, Ghozlani I, Ahmed B. Taoubane L, et al. Reumatologia. 2025 Sep 10;63(4):244-250. doi: 10.5114/reum/205366. eCollection 2025. Reumatologia. 2025. PMID: 41064386 Free PMC article.
Uveitis was the most frequent paradoxical reaction, found in 9 patients, followed by psoriasis in 7 patients, and then pyoderma gangrenosum, lichen, and granulomatous dermatitis in only 1 patient each. These paradoxical effects were found predominantly in men …
Uveitis was the most frequent paradoxical reaction, found in 9 patients, followed by psoriasis in 7 patients, and then pyoderm …
Etanercept-induced sarcoidosis presenting with bilateral panuveitis: diagnostic value of ocular signs and therapeutic response to IL-17A inhibition-a case-based review.
Bonifazi T, Cerquaglia A, Iaccheri B. Bonifazi T, et al. Clin Rheumatol. 2025 Dec;44(12):5123-5128. doi: 10.1007/s10067-025-07759-4. Epub 2025 Oct 18. Clin Rheumatol. 2025. PMID: 41107632 Free PMC article. Review.
To our knowledge, this is the first long-term report of etanercept-induced ocular sarcoidosis successfully managed with secukinumab, which allowed steroid withdrawal. While IL-17A inhibitors are not yet approved for uveitis, available data and our observation sugges …
To our knowledge, this is the first long-term report of etanercept-induced ocular sarcoidosis successfully managed with secukinumab, …
Behcet's-like disease induced by secukinumab in a patient with psoriasis: a case report and literature review.
Liu K, Sun J. Liu K, et al. J Dermatolog Treat. 2024 Dec;35(1):2347440. doi: 10.1080/09546634.2024.2347440. Epub 2024 Jun 10. J Dermatolog Treat. 2024. PMID: 38857894 Free article. Review.
Purpose: The incidence of cutaneous paradoxical reactions associated with IL-17 inhibitors has gained attention in recent literature. Our report aims to investigate the characteristics of one rare paradoxical reaction, presenting as Behcet's disease. Methods: We rep …
Purpose: The incidence of cutaneous paradoxical reactions associated with IL-17 inhibitors has gained attention in recent literature. …