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51 results

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Page 1
Are Seed Oils the Culprit in Cardiometabolic and Chronic Diseases? A Narrative Review.
Lee K, Kurniawan K. Lee K, et al. Nutr Rev. 2025 Jul 1;83(7):e2106-e2112. doi: 10.1093/nutrit/nuae205. Nutr Rev. 2025. PMID: 39820582 Review.
The demonization of seed oils "campaign" has become stronger over the decades. Despite the dietary guidelines provided by nutritional experts recommending the limiting of saturated fat intake and its replacement with unsaturated fat-rich food sources, some health ex …
The demonization of seed oils "campaign" has become stronger over the decades. Despite the dietary guidelines provided by nutr …
Perspective on the health effects of unsaturated fatty acids and commonly consumed plant oils high in unsaturated fat.
Petersen KS, Maki KC, Calder PC, Belury MA, Messina M, Kirkpatrick CF, Harris WS. Petersen KS, et al. Br J Nutr. 2024 Oct 28;132(8):1039-1050. doi: 10.1017/S0007114524002459. Epub 2024 Oct 30. Br J Nutr. 2024. PMID: 39475012 Free PMC article. Review.
Edible plant oils, commonly termed vegetable oils, are derived from vegetables, nuts, seeds, fruits and cereal grains. ...Importantly, clinical trials show that increased n-6 PUFA (linoleic acid) intake does not increase markers of inflammati …
Edible plant oils, commonly termed vegetable oils, are derived from vegetables, nuts, seeds, fruits and cereal grains. …
The Importance of Maintaining a Low Omega-6/Omega-3 Ratio for Reducing the Risk of Autoimmune Diseases, Asthma, and Allergies.
DiNicolantonio JJ, O'Keefe J. DiNicolantonio JJ, et al. Mo Med. 2021 Sep-Oct;118(5):453-459. Mo Med. 2021. PMID: 34658440 Free PMC article.
This predisposes to supraphysiologic inflammatory responses and perpetuates chronic low-grade inflammation. The overconsumption of linoleic acid, mainly from industrial omega-6 seed oils, and the lack of long-chain omega-3s in the diet creates a …
This predisposes to supraphysiologic inflammatory responses and perpetuates chronic low-grade inflammation. The overconsumption of …
Historical rise of cancer and dietary linoleic acid: Mechanisms and therapeutic strategies.
Mercola J. Mercola J. World J Clin Oncol. 2025 Sep 24;16(9):110686. doi: 10.5306/wjco.v16.i9.110686. World J Clin Oncol. 2025. PMID: 41024837 Free PMC article. Review.
Over the past century, dietary intake of linoleic acid (LA), an essential omega-6 fatty acid, has risen markedly in industrialized regions, largely due to industrial seed oils (e.g., soybean oil). ...A proposed "terrain restoration" protocol, em …
Over the past century, dietary intake of linoleic acid (LA), an essential omega-6 fatty acid, has risen markedly in ind …
The health implications of changing linoleic acid intakes.
Whelan J. Whelan J. Prostaglandins Leukot Essent Fatty Acids. 2008 Sep-Nov;79(3-5):165-7. doi: 10.1016/j.plefa.2008.09.013. Epub 2008 Nov 5. Prostaglandins Leukot Essent Fatty Acids. 2008. PMID: 18990554 Review.
Linoleic acid is the most prominent polyunsaturated fatty acid (PUFA) in the Western diet. It is virtually found in every food we eat and is the predominant PUFA in land-based meats, dairy, vegetables, vegetable oils, cereals, fruits, nuts, legumes, …
Linoleic acid is the most prominent polyunsaturated fatty acid (PUFA) in the Western diet. It is virtually found in eve …
Nutraceutical Potential of Grape (Vitis vinifera L.) Seed Oil in Oxidative Stress, Inflammation, Obesity and Metabolic Alterations.
Di Pietro Fernandes C, Santana LF, Dos Santos JR, Fernandes DS, Hiane PA, Pott A, Freitas KC, Bogo D, do Nascimento VA, Filiú WFO, Asato MA, Guimarães RCA. Di Pietro Fernandes C, et al. Molecules. 2023 Nov 28;28(23):7811. doi: 10.3390/molecules28237811. Molecules. 2023. PMID: 38067541 Free PMC article. Review.
(grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fatty acids such as linoleic acid (65-75%), vitamin E (50 mg), and phytosterols in addition to phenolic compounds, such as catec …
(grapevine) is a perennial plant of the Vitaceae family that is widely used to produce grapes and wines. Grape seed oil is rich in fa …
The effect of Oenothera biennis (Evening primrose) oil on inflammatory diseases: a systematic review of clinical trials.
Sharifi M, Nourani N, Sanaie S, Hamedeyazdan S. Sharifi M, et al. BMC Complement Med Ther. 2024 Feb 15;24(1):89. doi: 10.1186/s12906-024-04378-5. BMC Complement Med Ther. 2024. PMID: 38360611 Free PMC article.
BACKGROUND: Evening primrose oil (EPO), extracted from the seeds of Oenothera biennis, has gained attention for its therapeutic effects in various inflammatory conditions. ...
BACKGROUND: Evening primrose oil (EPO), extracted from the seeds of Oenothera biennis, has gained attention for its therapeutic effec …
Prospective clinical trial examining the impact of genetic variation in FADS1 on the metabolism of linoleic acid- and -linolenic acid-containing botanical oils.
Sergeant S, Hallmark B, Mathias RA, Mustin TL, Ivester P, Bohannon ML, Ruczinski I, Johnstone L, Seeds MC, Chilton FH. Sergeant S, et al. Am J Clin Nutr. 2020 May 1;111(5):1068-1078. doi: 10.1093/ajcn/nqaa023. Am J Clin Nutr. 2020. PMID: 32167131 Free PMC article. Clinical Trial.
BACKGROUND: Unexplained heterogeneity in clinical trials has resulted in questions regarding the effectiveness of -linolenic acid (GLA)-containing botanical oil supplements. This heterogeneity may be explained by genetic variation within the fatty acid desaturase ( …
BACKGROUND: Unexplained heterogeneity in clinical trials has resulted in questions regarding the effectiveness of -linolenic acid (G …
Mechanistic insights and clinical evidence of Helianthus annuus Linn. (Sunflower) seed oil for dermatological applications: A narrative review.
Lim HC, Lee SK, Keng JW, Lee EQ, Tan ESS, Liew KB, Mai CW, Lee SK, Chen L, Low ML, Chew YL. Lim HC, et al. Drug Deliv Transl Res. 2025 Nov;15(11):4260-4276. doi: 10.1007/s13346-025-01939-0. Epub 2025 Aug 9. Drug Deliv Transl Res. 2025. PMID: 40783675 Review.
Plant oils play an important role in natural product-based dermatological formulations owing to their multifunctional therapeutic properties. ...Rich in unsaturated fatty acids, particularly linoleic acid (LA) and oleic acid (OA), SSO supports skin hea …
Plant oils play an important role in natural product-based dermatological formulations owing to their multifunctional therapeutic pro …
Seed Oils as a Hypothesized Contributor to Heart Disease: A Narrative Synthesis.
Mercola J. Mercola J. Cureus. 2026 Jan 21;18(1):e102012. doi: 10.7759/cureus.102012. eCollection 2026 Jan. Cureus. 2026. PMID: 41728472 Free PMC article. Review.
Coronary heart disease (CHD) was relatively uncommon in the 19(th) century, when infectious illnesses dominated mortality, but it rose dramatically in the 20(th) century in parallel with major dietary shifts, including an increase in linoleic acid (LA), an essential …
Coronary heart disease (CHD) was relatively uncommon in the 19(th) century, when infectious illnesses dominated mortality, but it rose drama …
51 results