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Page 1
Personalized Supplementation Is Associated with Reduced Inflammatory Biomarkers: A 12-Week Observational Study.
Roeth E, Morris M, Reynolds AP, Reynolds EM, Hungerford R, Livingston EJ, Richardson AW, Bikman BT, Reynolds PR. Roeth E, et al. Life (Basel). 2025 Dec 10;15(12):1887. doi: 10.3390/life15121887. Life (Basel). 2025. PMID: 41465826 Free PMC article.
Personalized protocols were developed based on individual biomarker profiles and included targeted interventions with vitamin D, omega-3 fatty acids, B vitamins, zinc, selenium, hormone optimization, and other supportive agents. Primary outcomes were percent changes in CRP …
Personalized protocols were developed based on individual biomarker profiles and included targeted interventions with vitamin D, omega-3 fat …
Effect of Selenium-Enriched Yeast Supplementation on Serum Thyroid-Stimulating Hormone and Anti-Thyroid Peroxidase Antibody Levels in Subclinical Hypothyroidism: Randomized Controlled Trial.
Mahmoudi L, Mobasseri M, Ostadrahimi A, Pourmoradian S, Soleimanzadeh H, Kafili B. Mahmoudi L, et al. Adv Biomed Res. 2021 Oct 27;10:33. doi: 10.4103/abr.abr_252_20. eCollection 2021. Adv Biomed Res. 2021. PMID: 34909430 Free PMC article.
BACKGROUND: In the subclinical hypothyroidism, T4 or T3 levels are normal and thyroid-stimulating hormone (TSH) is slightly high. Selenium deficiency can lead to thyroid dysfunction. The present study aims to investigate the effect of selenium supplementation on the …
BACKGROUND: In the subclinical hypothyroidism, T4 or T3 levels are normal and thyroid-stimulating hormone (TSH) is slightly high. Seleniu …
Selenium supplementation for Hashimoto's thyroiditis.
van Zuuren EJ, Albusta AY, Fedorowicz Z, Carter B, Pijl H. van Zuuren EJ, et al. Cochrane Database Syst Rev. 2013 Jun 6;2013(6):CD010223. doi: 10.1002/14651858.CD010223.pub2. Cochrane Database Syst Rev. 2013. PMID: 23744563 Free PMC article.

In a further comparison within the first study where selenomethionine was combined with LT4 the reduction in TPO antibodies was even more noticeable (MD -1508 U/mL, 95% CI -1671 to -1345; P < 0.001; 86 participants). In a third study, where LT4 was added t

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In a further comparison within the first study where selenomethionine was combined with LT4 the reduction in TPO antibodies …
Selenium supplementation in thyroid associated ophthalmopathy: an update.
Dharmasena A. Dharmasena A. Int J Ophthalmol. 2014 Apr 18;7(2):365-75. doi: 10.3980/j.issn.2222-3959.2014.02.31. eCollection 2014. Int J Ophthalmol. 2014. PMID: 24790886 Free PMC article. Review.
The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). ...These mechanisms include 1) inhibitory effect of HLA-DR molecule expression on thyrocytes; 2) profound reductions of thyroid stimulatin …
The therapeutic effect of selenium (Se) has already been proven in thyroid disease and thyroid associated ophthalmopathy (TAO). ...Th …
Association Between Essential Trace Elements and Thyroid Antibodies in the Blood of Women with Newly Diagnosed Hashimoto's Thyroiditis.
Rostami R, Beiranvand A, Nourooz-Zadeh S, Rostami M, Mohammadi A, Nourooz-Zadeh J. Rostami R, et al. Int J Endocrinol Metab. 2024 Aug 12;22(2):e145599. doi: 10.5812/ijem-145599. eCollection 2024 Apr. Int J Endocrinol Metab. 2024. PMID: 40071251 Free PMC article.

Pearson correlation analysis revealed a significant inverse correlation between serum Se, Zn, and Cu with thyroid peroxidase antibody (TPO-Ab) and thyroglobulin antibody (Tg-Ab) levels (P < 0.001). While no significant correlation was observed between thyr

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Pearson correlation analysis revealed a significant inverse correlation between serum Se, Zn, and Cu with thyroid peroxidase antibody …
Supplementation with myo-inositol and Selenium improves the clinical conditions and biochemical features of women with or at risk for subclinical hypothyroidism.
Payer J, Jackuliak P, Kužma M, Džupon M, Vaňuga P. Payer J, et al. Front Endocrinol (Lausanne). 2022 Nov 16;13:1067029. doi: 10.3389/fendo.2022.1067029. eCollection 2022. Front Endocrinol (Lausanne). 2022. PMID: 36465640 Free PMC article.
The patients included at the enrollment were women of reproductive age (18-50), who exhibit values of TSH in the range 2.5-5 mU/l and positivity to antibodies TPO-Ab/TG-Ab, or otherwise values of TSH in the range 5-10 mU/l both with and without positivity to anti …
The patients included at the enrollment were women of reproductive age (18-50), who exhibit values of TSH in the range 2.5-5 mU/l and positi …
l-selenomethionine supplementation in children and adolescents with autoimmune thyroiditis: A randomized double-blind placebo-controlled clinical trial.
Kyrgios I, Giza S, Kotanidou EP, Kleisarchaki A, Tsinopoulou VR, Papadopoulou A, Markantonatou AM, Kanellidou E, Giannakou A, Galli-Tsinopoulou A. Kyrgios I, et al. J Clin Pharm Ther. 2019 Feb;44(1):102-108. doi: 10.1111/jcpt.12765. Epub 2018 Oct 10. J Clin Pharm Ther. 2019. PMID: 30306604 Clinical Trial.
WHAT IS KNOWN AND OBJECTIVE: Although a beneficial effect of selenium (Se) administration has been proposed in adults with autoimmune thyroiditis (AT), there is a paucity of similar data in children and adolescents. The purpose of the study was to investigate whether admin …
WHAT IS KNOWN AND OBJECTIVE: Although a beneficial effect of selenium (Se) administration has been proposed in adults with autoimmune …
The Impact of Selenium Deficiency and Supplementation on Hashimoto's Thyroiditis: A Clinical Evaluation.
Acik H, Aydin Y. Acik H, et al. Endocr Metab Immune Disord Drug Targets. 2026 Apr 28. doi: 10.2174/0118715303424962251204064911. Online ahead of print. Endocr Metab Immune Disord Drug Targets. 2026. PMID: 42083539
Biochemical parameters, including Se, thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), anti-thyroid peroxidase (anti-TPO), and anti-thyroglobulin (anti-Tg) antibodies, were compared. Se-deficient HT patients (<80 g/L) receive …
Biochemical parameters, including Se, thyroid-stimulating hormone (TSH), free triiodothyronine (FT3), free thyroxine (FT4), anti-thyroid per …
Influence of physiological dietary selenium supplementation on the natural course of autoimmune thyroiditis.
Nacamulli D, Mian C, Petricca D, Lazzarotto F, Barollo S, Pozza D, Masiero S, Faggian D, Plebani M, Girelli ME, Mantero F, Betterle C. Nacamulli D, et al. Clin Endocrinol (Oxf). 2010 Oct;73(4):535-9. doi: 10.1111/j.1365-2265.2009.03758.x. Clin Endocrinol (Oxf). 2010. PMID: 20039895
Thyroperoxidase and thyroglobulin autoantibodies (TPO-Ab; Tg-Ab), TSH, fT4 and urine iodine concentrations (UIC) were measured at baseline and after 6 and 12 months of follow-up. ...CONCLUSIONS: Dietary supplementation with physiological doses of Se seems to be effective i …
Thyroperoxidase and thyroglobulin autoantibodies (TPO-Ab; Tg-Ab), TSH, fT4 and urine iodine concentrations (UIC) were measured at bas …
Proof of concept of the WOMED model of benign thyroid disease: Restitution of thyroid morphology after correction of physical and psychological stressors and magnesium supplementation.
Moncayo R, Moncayo H. Moncayo R, et al. BBA Clin. 2014 Dec 31;3:113-22. doi: 10.1016/j.bbacli.2014.12.005. eCollection 2015 Jun. BBA Clin. 2014. PMID: 26672672 Free PMC article.
BACKGROUND: The aim of this study was to investigate the influence of a combined supplementation with magnesium, selenium and coenzyme Q10 on the morphology of the thyroid in patients with benign diseases. ...After a period of 2-4 years of supplementation we observed a nor …
BACKGROUND: The aim of this study was to investigate the influence of a combined supplementation with magnesium, selenium and coenzym …
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