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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1988 1
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1999 1
2002 1
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2008 2
2009 2
2010 2
2011 4
2012 5
2013 5
2014 6
2015 3
2016 6
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88 results

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Page 1
Astrocytes as Key Regulators of Neural Signaling in Health and Disease.
Won W, Bhalla M, Lee JH, Lee CJ. Won W, et al. Annu Rev Neurosci. 2025 Jul;48(1):251-276. doi: 10.1146/annurev-neuro-112723-035356. Epub 2025 Mar 11. Annu Rev Neurosci. 2025. PMID: 40067961 Free article. Review.
They actively engage in synaptic transmission and brain health by releasing gliotransmitters such as glutamate, GABA, ATP, adenosine, lactate, and d-serine. ...This review explores the multifaceted roles of astrocytes in health and disease, emphasizing sensory and m …
They actively engage in synaptic transmission and brain health by releasing gliotransmitters such as glutamate, GABA, ATP, adenosine, …
Ataxia-Telangiectasia.
Veenhuis S, van Os N, Weemaes C, Kamsteeg EJ, Willemsen M. Veenhuis S, et al. 1999 Mar 19 [updated 2025 Dec 4]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. 1999 Mar 19 [updated 2025 Dec 4]. In: Adam MP, Bick S, Mirzaa GM, Pagon RA, Wallace SE, Amemiya A, editors. GeneReviews® [Internet]. Seattle (WA): University of Washington, Seattle; 1993–2026. PMID: 20301790 Free Books & Documents. Review.
Classic A-T is characterized by childhood onset of progressive neurologic manifestations (initially cerebellar ataxia, followed typically by extrapyramidal involvement and peripheral sensorimotor neuropathy), immunodeficiency (variably associated with abnormalities of humo …
Classic A-T is characterized by childhood onset of progressive neurologic manifestations (initially cerebellar ataxia, followed typic …
Framework for Brain-Derived Dimensions of Psychopathology.
Lett TA, Vaidya N, Jia T, Polemiti E, Banaschewski T, Bokde ALW, Flor H, Grigis A, Garavan H, Gowland P, Heinz A, Brühl R, Martinot JL, Paillère Martinot ML, Artiges E, Nees F, Papadopoulos Orfanos D, Lemaitre H, Paus T, Poustka L, Stringaris A, Waller L, Zhang Z, Winterer J, Zhang Y, Smolka MN, Whelan R, Schmidt U, Sinclair J, Walter H, Feng J, Robbins TW, Desrivières S, Marquand A, Schumann G; IMAGEN Consortium and the environMENTAL Consortium. Lett TA, et al. JAMA Psychiatry. 2025 Aug 1;82(8):778-789. doi: 10.1001/jamapsychiatry.2025.1246. JAMA Psychiatry. 2025. PMID: 40531512 Free PMC article.
OBJECTIVE: To develop a framework that groups clinical symptoms compatible with ICD-10 and DSM-5 according to their covariation and shared brain mechanisms. DESIGN, SETTING, AND PARTICIPANTS: This diagnostic study was conducted in 2 samples, the population-based Reinforcem …
OBJECTIVE: To develop a framework that groups clinical symptoms compatible with ICD-10 and DSM-5 according to their covariation and shared …
Astrocyte-mediated regulation of BLAWFS1 neurons alleviates risk-assessment deficits in DISC1-N mice.
Zhou X, Xiao Q, Liu Y, Chen S, Xu X, Zhang Z, Hong Y, Shao J, Chen Y, Chen Y, Wang L, Yang F, Tu J. Zhou X, et al. Neuron. 2024 Jul 3;112(13):2197-2217.e7. doi: 10.1016/j.neuron.2024.03.028. Epub 2024 Apr 19. Neuron. 2024. PMID: 38642554 Free article.
Unfortunately, many mental illnesses involve impaired risk assessment, affecting patients, families, and society. The brain processes behind these behaviors are not well understood. We developed a transgenic mouse model (disrupted-in-schizophrenia 1 [DISC1]-N) with a disru …
Unfortunately, many mental illnesses involve impaired risk assessment, affecting patients, families, and society. The brain processes …
The tripartite glutamatergic synapse.
Lalo U, Koh W, Lee CJ, Pankratov Y. Lalo U, et al. Neuropharmacology. 2021 Nov 1;199:108758. doi: 10.1016/j.neuropharm.2021.108758. Epub 2021 Aug 22. Neuropharmacology. 2021. PMID: 34433089 Review.
Astroglial cells were long considered as structural and metabolic supporting cells are which do not directly participate in information processing in the brain. Discoveries of responsiveness of astrocytes to synaptically-released glutamate and their capability to release a …
Astroglial cells were long considered as structural and metabolic supporting cells are which do not directly participate in information proc …
Neuronal connectivity, behavioral, and transcriptional alterations associated with the loss of MARK2.
Caiola HO, Wu Q, Li J, Wang XF, Soni S, Monahan K, Wagner GC, Pang ZP, Zhang H. Caiola HO, et al. FASEB J. 2024 Oct 31;38(20):e70124. doi: 10.1096/fj.202400454R. FASEB J. 2024. PMID: 39436150 Free PMC article.
Neuronal connectivity is essential for adaptive brain responses and can be modulated by dendritic spine plasticity and the intrinsic excitability of individual neurons. ...However, despite its genetic association with several neurological disorders, the in vivo impa …
Neuronal connectivity is essential for adaptive brain responses and can be modulated by dendritic spine plasticity and the intrinsic …
Digenic inheritance involving a muscle-specific protein kinase and the giant titin protein causes a skeletal muscle myopathy.
Töpf A, Cox D, Zaharieva IT, Di Leo V, Sarparanta J, Jonson PH, Sealy IM, Smolnikov A, White RJ, Vihola A, Savarese M, Merteroglu M, Wali N, Laricchia KM, Venturini C, Vroling B, Stenton SL, Cummings BB, Harris E, Marini-Bettolo C, Diaz-Manera J, Henderson M, Barresi R, Duff J, England EM, Patrick J, Al-Husayni S, Biancalana V, Beggs AH, Bodi I, Bommireddipalli S, Bönnemann CG, Cairns A, Chiew MT, Claeys KG, Cooper ST, Davis MR, Donkervoort S, Erasmus CE, Fassad MR, Genetti CA, Grosmann C, Jungbluth H, Kamsteeg EJ, Lornage X, Löscher WN, Malfatti E, Manzur A, Martí P, Mongini TE, Muelas N, Nishikawa A, O'Donnell-Luria A, Ogonuki N, O'Grady GL, O'Heir E, Paquay S, Phadke R, Pletcher BA, Romero NB, Schouten M, Shah S, Smuts I, Sznajer Y, Tasca G, Taylor RW, Tuite A, Van den Bergh P, VanNoy G, Voermans NC, Wanschitz JV, Wraige E, Yoshimura K, Oates EC, Nakagawa O, Nishino I, Laporte J, Vilchez JJ, MacArthur DG, Sarkozy A, Cordell HJ, Udd B, Busch-Nentwich EM, Muntoni F, Straub V. Töpf A, et al. Nat Genet. 2024 Mar;56(3):395-407. doi: 10.1038/s41588-023-01651-0. Epub 2024 Mar 1. Nat Genet. 2024. PMID: 38429495 Free PMC article.
Here we show that predicted deleterious variants in SRPK3, encoding the X-linked serine/argenine protein kinase 3, lead to a progressive early onset skeletal muscle myopathy only when in combination with heterozygous variants in the TTN gene. ...
Here we show that predicted deleterious variants in SRPK3, encoding the X-linked serine/argenine protein kinase 3, lead to a progress …
mTOR in Brain Physiology and Pathologies.
Bockaert J, Marin P. Bockaert J, et al. Physiol Rev. 2015 Oct;95(4):1157-87. doi: 10.1152/physrev.00038.2014. Physiol Rev. 2015. PMID: 26269525 Free article. Review.
In addition, mTOR-controlled signaling pathways regulate many integrated physiological functions of the nervous system including neuronal development, synaptic plasticity, memory storage, and cognition. Thus it is not surprising that deregulation of mTOR signaling is assoc …
In addition, mTOR-controlled signaling pathways regulate many integrated physiological functions of the nervous system including neuronal de …
L-Serine Influences Epigenetic Modifications to Improve Cognition and Behaviors in Growth Hormone-Releasing Hormone Knockout Mice.
Zhang F, Icyuz M, Tollefsbol T, Cox PA, Banack SA, Sun LY. Zhang F, et al. Biomedicines. 2022 Dec 30;11(1):104. doi: 10.3390/biomedicines11010104. Biomedicines. 2022. PMID: 36672612 Free PMC article.
The amino acid L-serine has been shown to have beneficial effects on neurological symptoms. Here, we found that growth hormone-releasing hormone knockout (GHRH-KO) mice, a GH-deficiency mouse model characterized by extended lifespan and enhanced insulin sensitivity, …
The amino acid L-serine has been shown to have beneficial effects on neurological symptoms. Here, we found that growth hormone …
The role of Cdk5 in cognition and neuropsychiatric and neurological pathology.
Barnett DG, Bibb JA. Barnett DG, et al. Brain Res Bull. 2011 Apr 25;85(1-2):9-13. doi: 10.1016/j.brainresbull.2010.11.016. Epub 2010 Dec 7. Brain Res Bull. 2011. PMID: 21145377 Free PMC article. Review.
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that is ubiquitous in the nervous system and interacts with a myriad of substrates. Its modulation of synaptic plasticity and associated mechanisms of learning and memory as well as neurodegener …
Cyclin-dependent kinase 5 (Cdk5) is a proline-directed serine/threonine kinase that is ubiquitous in the nervous system and interacts …
88 results