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2010 47
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1,905 results

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Page 1
Diabetic Ketoacidosis: Evaluation and Treatment.
Veauthier B, Levy-Grau B. Veauthier B, et al. Am Fam Physician. 2024 Nov;110(5):476-486. Am Fam Physician. 2024. PMID: 39556629 Review.
Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 and type 2 diabetes resulting from an absolute or relative insulin deficiency. It can occur in patients of all ages and can be the initial presentation of diabetes, especia …
Diabetic ketoacidosis (DKA) is a life-threatening complication of type 1 and type 2 diabetes resulting from an absolute or rel …
Insulin-dependent diabetes mellitus: pathophysiology.
Gerich JE. Gerich JE. Mayo Clin Proc. 1986 Oct;61(10):787-91. doi: 10.1016/s0025-6196(12)64818-6. Mayo Clin Proc. 1986. PMID: 3528691 Review.
Diabetes mellitus is a heterogeneous disorder. About 80% of the patients with this disease are categorized as having non-insulin-dependent diabetes mellitus, a disorder resulting from varied degrees of insulin resistance and impaired i …
Diabetes mellitus is a heterogeneous disorder. About 80% of the patients with this disease are categorized as having non-in …
Pathophysiology, phenotypes and management of type 2 diabetes mellitus in Indian and Chinese populations.
Ke C, Narayan KMV, Chan JCN, Jha P, Shah BR. Ke C, et al. Nat Rev Endocrinol. 2022 Jul;18(7):413-432. doi: 10.1038/s41574-022-00669-4. Epub 2022 May 4. Nat Rev Endocrinol. 2022. PMID: 35508700 Free PMC article. Review.
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These populations have an underlying predisposition to deficient insulin secretion, which has a key role in the pathogenesis of T2DM. ...Cluster-based phenotypic an …
Nearly half of all adults with type 2 diabetes mellitus (T2DM) live in India and China. These populations have an underlying p …
Severe insulin-deficient diabetes is at the opposite end of the neuropathy spectrum to mild aged-related diabetes.
Callaghan BC, Anjana RM, Muthukumar L, Reynolds EL, Saravanan J, Vignesh MA, Mukundan A, Feldman EL, Mohan V. Callaghan BC, et al. J Diabetes Investig. 2025 Jun;16(6):1045-1049. doi: 10.1111/jdi.70033. Epub 2025 Mar 27. J Diabetes Investig. 2025. PMID: 40145817 Free PMC article.
The effect of diabetes subtypes on neuropathy prevalence and metabolic drivers of this relationship are unknown. ...Neuropathy prevalence was highest in severe insulin-deficient diabetes (SIDD; 25.5%), followed by insulin-resistant obese …
The effect of diabetes subtypes on neuropathy prevalence and metabolic drivers of this relationship are unknown. ...Neuropathy preval …
SGLT2 Inhibitor-associated Diabetic Ketoacidosis: Clinical Review and Recommendations for Prevention and Diagnosis.
Goldenberg RM, Berard LD, Cheng AYY, Gilbert JD, Verma S, Woo VC, Yale JF. Goldenberg RM, et al. Clin Ther. 2016 Dec;38(12):2654-2664.e1. doi: 10.1016/j.clinthera.2016.11.002. Clin Ther. 2016. PMID: 28003053 Review.
Patients with SGLT2 inhibitor-associated DKA may be euglycemic (plasma glucose level <14 mmol/L). DKA is more likely in patients with insulin-deficient diabetes, including those with type 2 diabetes, and is typically precipitated by insulin o …
Patients with SGLT2 inhibitor-associated DKA may be euglycemic (plasma glucose level <14 mmol/L). DKA is more likely in patients with …
Hypoglycaemia unawareness.
Meijer E, Hoekstra JB, Erkelens DW. Meijer E, et al. Presse Med. 1994 Apr 2;23(13):623-7. Presse Med. 1994. PMID: 8029194 Review.
Hypoglycaemia is a severe complication of insulin-dependent diabetes mellitus, especially when it is not preceded by warning signs. ...While the pathophysiology of hypoglycemia unawareness remains unclear in patients with insulin-dependent di …
Hypoglycaemia is a severe complication of insulin-dependent diabetes mellitus, especially when it is not precede …
Advanced hybrid closed loop therapy versus conventional treatment in adults with type 1 diabetes (ADAPT): a randomised controlled study.
Choudhary P, Kolassa R, Keuthage W, Kroeger J, Thivolet C, Evans M, Ré R, de Portu S, Vorrink L, Shin J, Habteab A, Castañeda J, da Silva J, Cohen O; ADAPT study Group. Choudhary P, et al. Lancet Diabetes Endocrinol. 2022 Oct;10(10):720-731. doi: 10.1016/S2213-8587(22)00212-1. Epub 2022 Sep 1. Lancet Diabetes Endocrinol. 2022. PMID: 36058207 Clinical Trial.
Safety endpoints included the number of device deficiencies, severe hypoglycaemic events, diabetic ketoacidosis, and serious adverse events. ...No diabetic ketoacidosis, severe hypoglycaemia, or serious adverse events related to study devices oc …
Safety endpoints included the number of device deficiencies, severe hypoglycaemic events, diabetic ketoacidosis, and se …
Achievements, prospects and challenges in precision care for monogenic insulin-deficient and insulin-resistant diabetes.
Bonnefond A, Semple RK. Bonnefond A, et al. Diabetologia. 2022 Nov;65(11):1782-1795. doi: 10.1007/s00125-022-05720-7. Epub 2022 May 27. Diabetologia. 2022. PMID: 35618782 Free PMC article. Review.
Monogenic diabetes may be divided into primary pancreatic beta cell failure, and primary insulin resistance. ...In monogenic insulin-resistant diabetes, subcutaneous leptin therapy is beneficial in some severe lipodystrophy. ...
Monogenic diabetes may be divided into primary pancreatic beta cell failure, and primary insulin resistance. ...In monogenic …
Exercise and diabetes.
De Feo P, Di Loreto C, Ranchelli A, Fatone C, Gambelunghe G, Lucidi P, Santeusanio F. De Feo P, et al. Acta Biomed. 2006;77 Suppl 1:14-7. Acta Biomed. 2006. PMID: 16921608 Review.
On the other hand, exercise-induced activation of counterregulatory hormones might trigger an acute metabolic derangement in severe insulin-deficient subjects. Thus, diabetic patients, before starting exercise sessions, must be carefully educated about …
On the other hand, exercise-induced activation of counterregulatory hormones might trigger an acute metabolic derangement in severe …
Vitamin E treatment in insulin-deficient diabetic rats reduces cardiac arrhythmias and mortality during severe hypoglycemia.
Reno-Bernstein CM, Oxspring M, Bayles J, Huang EY, Holiday I, Fisher SJ. Reno-Bernstein CM, et al. Am J Physiol Endocrinol Metab. 2022 Nov 1;323(5):E428-E434. doi: 10.1152/ajpendo.00188.2022. Epub 2022 Oct 5. Am J Physiol Endocrinol Metab. 2022. PMID: 36198111 Free PMC article.
Increased oxidative stress associated with insulin-deficient diabetes was hypothesized to increase susceptibility to severe hypoglycemia-induced fatal cardiac arrhythmias. ...We show in our animal model that insulin-deficient diabetic …
Increased oxidative stress associated with insulin-deficient diabetes was hypothesized to increase susceptibility to …
1,905 results