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2008 1
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Page 1
Loss of SPHK1 fuels inflammation to drive KRAS-mutated lung adenocarcinoma.
Luca AC, Kurnaeva M, John DK, Machtinger M, Vollmer NHJ, Mödl B, Hannich JT, Eckhard M, Lam HS, Musiejovsky L, Trenk C, Homolya M, Fürnsinn C, Sombke A, Schabbauer G, Eferl R, Sharif O, Casanova E, Moll HP. Luca AC, et al. Cancer Lett. 2025 Jul 28;623:217733. doi: 10.1016/j.canlet.2025.217733. Epub 2025 Apr 18. Cancer Lett. 2025. PMID: 40254091 Free article.
Itaconate is a metabolic regulator of bone formation in homeostasis and arthritis.
Kieler M, Prammer LS, Heller G, Hofmann M, Sperger S, Hanetseder D, Niederreiter B, Komljenovic A, Klavins K, Köcher T, Brunner JS, Stanic I, Oberbichler L, Korosec A, Vogel A, Kerndl M, Hromadová D, Musiejovsky L, Hajto A, Dobrijevic A, Piwonka T, Haschemi A, Miller A, Georgel P, Marolt Presen D, Grillari J, Hayer S, Auger JP, Krönke G, Sharif O, Aletaha D, Schabbauer G, Blüml S. Kieler M, et al. Ann Rheum Dis. 2024 Oct 21;83(11):1465-1479. doi: 10.1136/ard-2023-224898. Ann Rheum Dis. 2024. PMID: 38986577 Free PMC article.
TREM-2 plays a protective role in cholestasis by acting as a negative regulator of inflammation.
Labiano I, Agirre-Lizaso A, Olaizola P, Echebarria A, Huici-Izagirre M, Olaizola I, Esparza-Baquer A, Sharif O, Hijona E, Milkiewicz P, Milkiewicz M, González-Romero F, Aspichueta P, Monte MJ, Marin JJG, Vucur M, Luedde T, Marzioni M, Mann DA, Bujanda L, Rodrigues PM, Banales JM, Perugorria MJ. Labiano I, et al. J Hepatol. 2022 Oct;77(4):991-1004. doi: 10.1016/j.jhep.2022.05.044. Epub 2022 Jun 22. J Hepatol. 2022. PMID: 35750136 Free article.
PI3K Signaling in Dendritic Cells Aggravates DSS-Induced Colitis.
Kuttke M, Hromadová D, Yildirim C, Brunner JS, Vogel A, Paar H, Peters S, Weber M, Hofmann M, Kerndl M, Kieler M, Datler H, Musiejovsky L, Salzmann M, Lang M, Soukup K, Halfmann A, Sharif O, Schabbauer G. Kuttke M, et al. Front Immunol. 2022 Apr 19;13:695576. doi: 10.3389/fimmu.2022.695576. eCollection 2022. Front Immunol. 2022. PMID: 35514976 Free PMC article.
Lipid scavenging macrophages and inflammation.
Vogel A, Brunner JS, Hajto A, Sharif O, Schabbauer G. Vogel A, et al. Biochim Biophys Acta Mol Cell Biol Lipids. 2022 Jan;1867(1):159066. doi: 10.1016/j.bbalip.2021.159066. Epub 2021 Oct 6. Biochim Biophys Acta Mol Cell Biol Lipids. 2022. PMID: 34626791 Free article. Review.
33 results