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1953 5
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1955 2
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1958 3
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41,451 results

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Page 1
Shedding light on GPIbalpha shedding.
Debaene C, Feys HB, Six KR. Debaene C, et al. Curr Opin Hematol. 2024 Sep 1;31(5):224-229. doi: 10.1097/MOH.0000000000000826. Epub 2024 May 9. Curr Opin Hematol. 2024. PMID: 38728102 Review.
PURPOSE OF REVIEW: Ectodomain shedding has been investigated since the late 1980s. The abundant and platelet specific GPIbalpha receptor is cleaved by ADAM17 resulting in the release of its ectodomain called glycocalicin. ...In physiological settings, GPIbalpha shedding …
PURPOSE OF REVIEW: Ectodomain shedding has been investigated since the late 1980s. The abundant and platelet specific GPIbalpha recep …
SARS-CoV-2 shedding sources in wastewater and implications for wastewater-based epidemiology.
Li X, Kulandaivelu J, Guo Y, Zhang S, Shi J, O'Brien J, Arora S, Kumar M, Sherchan SP, Honda R, Jackson G, Luby SP, Jiang G. Li X, et al. J Hazard Mater. 2022 Jun 15;432:128667. doi: 10.1016/j.jhazmat.2022.128667. Epub 2022 Mar 10. J Hazard Mater. 2022. PMID: 35339834 Free PMC article.
Wastewater-based epidemiology (WBE) approach for COVID-19 surveillance is largely based on the assumption of SARS-CoV-2 RNA shedding into sewers by infected individuals. Recent studies found that SARS-CoV-2 RNA concentration in wastewater (C(RNA)) could not be accounted by …
Wastewater-based epidemiology (WBE) approach for COVID-19 surveillance is largely based on the assumption of SARS-CoV-2 RNA shedding …
Virus Shedding of Avian Influenza in Poultry: A Systematic Review and Meta-Analysis.
Germeraad EA, Sanders P, Hagenaars TJ, Jong MCM, Beerens N, Gonzales JL. Germeraad EA, et al. Viruses. 2019 Sep 2;11(9):812. doi: 10.3390/v11090812. Viruses. 2019. PMID: 31480744 Free PMC article.
Understanding virus shedding patterns of avian influenza virus (AIV) in poultry is important for understanding host-pathogen interactions and developing effective control strategies. ...In conclusion, this study highlights the need to standardize experimental procedures, i …
Understanding virus shedding patterns of avian influenza virus (AIV) in poultry is important for understanding host-pathogen interact …
Impact of Epithelial Cell Shedding on Intestinal Homeostasis.
Ngo PA, Neurath MF, López-Posadas R. Ngo PA, et al. Int J Mol Sci. 2022 Apr 9;23(8):4160. doi: 10.3390/ijms23084160. Int J Mol Sci. 2022. PMID: 35456978 Free PMC article. Review.
As the last step within the epithelial turnover, cell shedding occurs due to the pressure of cell division and migration from the base of the crypt. ...In this review, we summarized the current knowledge about intestinal cell shedding under both physiological and pa …
As the last step within the epithelial turnover, cell shedding occurs due to the pressure of cell division and migration from the bas …
Shedding of ciliary vesicles at a glance.
Ojeda Naharros I, Nachury MV. Ojeda Naharros I, et al. J Cell Sci. 2022 Oct 1;135(19):jcs246553. doi: 10.1242/jcs.246553. Epub 2022 Oct 12. J Cell Sci. 2022. PMID: 36222105 Free PMC article.
Extracellular vesicles (EVs) that bud from the ciliary membrane have well-studied roles in the disposal of excess ciliary material, most dramatically exemplified by the shedding of micrometer-sized blocks by photoreceptors. Shedding of EVs by cilia also affords cell …
Extracellular vesicles (EVs) that bud from the ciliary membrane have well-studied roles in the disposal of excess ciliary material, most dra …
Prolonged viral shedding in feces of children with COVID-19: a systematic review and synthesis of data.
Li WT, Zhang Y, Liu M, Liu YQ, Ma X. Li WT, et al. Eur J Pediatr. 2022 Dec;181(12):4011-4017. doi: 10.1007/s00431-022-04622-5. Epub 2022 Sep 17. Eur J Pediatr. 2022. PMID: 36114833 Free PMC article. Review.
In this review, we collected relevant literature to summarize the duration of fecal viral shedding in children with COVID-19. We found that in about 60% of the cases, the fecal shedding time was between 28 and 42 days, which was much longer than that of adults. ...C …
In this review, we collected relevant literature to summarize the duration of fecal viral shedding in children with COVID-19. We foun …
Understanding viral shedding of severe acute respiratory coronavirus virus 2 (SARS-CoV-2): Review of current literature.
Fontana LM, Villamagna AH, Sikka MK, McGregor JC. Fontana LM, et al. Infect Control Hosp Epidemiol. 2021 Jun;42(6):659-668. doi: 10.1017/ice.2020.1273. Epub 2020 Oct 20. Infect Control Hosp Epidemiol. 2021. PMID: 33077007 Free PMC article. Review.
We reviewed available literature to reach an evidenced-based consensus on the expected duration of viral shedding. DESIGN: We queried 4 scholarly repositories and search engines for studies reporting SARS-CoV-2 viral shedding dynamics by PCR and/or culture available …
We reviewed available literature to reach an evidenced-based consensus on the expected duration of viral shedding. DESIGN: We queried …
Actin polymerization regulates glycoprotein Ibalpha shedding.
Zhou K, Xia Y, Yang M, Xiao W, Zhao L, Hu R, Shoaib KM, Yan R, Dai K. Zhou K, et al. Platelets. 2022 Apr 3;33(3):381-389. doi: 10.1080/09537104.2021.1922882. Epub 2021 May 12. Platelets. 2022. PMID: 33979555 Free article.
However, the mechanism of GPIbalpha shedding remains elusive. Here, we show that jasplakinolide (an actin-polymerizing peptide)-induced actin polymerization results in GPIbalpha shedding and impairs platelet function. Thrombin and A23187-induced GPIbalpha sheddin …
However, the mechanism of GPIbalpha shedding remains elusive. Here, we show that jasplakinolide (an actin-polymerizing peptide)-induc …
Variant-specific SARS-CoV-2 shedding rates in wastewater.
Prasek SM, Pepper IL, Innes GK, Slinski S, Betancourt WQ, Foster AR, Yaglom HD, Porter WT, Engelthaler DM, Schmitz BW. Prasek SM, et al. Sci Total Environ. 2023 Jan 20;857(Pt 1):159165. doi: 10.1016/j.scitotenv.2022.159165. Epub 2022 Oct 3. Sci Total Environ. 2023. PMID: 36195153 Free PMC article.
Previous studies show that SARS-CoV-2 waste shedding rates vary by community and are influenced by multiple factors; however, differences in shedding rates across multiple variants have yet to be evaluated. The purpose of this work is to build on previous research t …
Previous studies show that SARS-CoV-2 waste shedding rates vary by community and are influenced by multiple factors; however, differe …
Basic mechanisms of platelet receptor shedding.
Andrews RK, Gardiner EE. Andrews RK, et al. Platelets. 2017 Jun;28(4):319-324. doi: 10.1080/09537104.2016.1235690. Epub 2016 Oct 25. Platelets. 2017. PMID: 27778531 Free article. Review.
Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-binding capacity, and for regulating platelet function in health and disease. ...This review will consider the key components of platelet rec …
Proteolytic shedding of the extracellular ectodomain of platelet receptors provides a key mechanism for irreversible loss of ligand-b …
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