shimada ichio - Search Results

Year	Number of Results
2002	5
2003	5
2004	7
2005	8
2006	6
2007	10
2008	7
2009	11
2010	15
2011	8
2012	17
2013	9
2014	10
2015	8
2016	6
2017	7
2018	10
2019	8
2020	9
2021	3

1

GPCR drug discovery: integrating solution NMR data with crystal and cryo-EM structures.

Shimada I, Ueda T, Kofuku Y, Eddy MT, Wüthrich K. Shimada I, et al. Nat Rev Drug Discov. 2019 Jan;18(1):59-82. doi: 10.1038/nrd.2018.180. Epub 2018 Nov 9. Nat Rev Drug Discov. 2019. PMID: 30410121 Free PMC article. Review.

2

Targeting FROUNT with disulfiram suppresses macrophage accumulation and its tumor-promoting properties.

Terashima Y, Toda E, Itakura M, Otsuji M, Yoshinaga S, Okumura K, Shand FHW, Komohara Y, Takeda M, Kokubo K, Chen MC, Yokoi S, Rokutan H, Kofuku Y, Ohnishi K, Ohira M, Iizasa T, Nakano H, Okabe T, Kojima H, Shimizu A, Kanegasaki S, Zhang MR, Shimada I, Nagase H, Terasawa H, Matsushima K. Terashima Y, et al. Among authors: shimada i. Nat Commun. 2020 Jan 30;11(1):609. doi: 10.1038/s41467-020-14338-5. Nat Commun. 2020. PMID: 32001710 Free PMC article.

3

Structural equilibrium underlying ligand-dependent activation of β₂-adrenoreceptor.

Imai S, Yokomizo T, Kofuku Y, Shiraishi Y, Ueda T, Shimada I. Imai S, et al. Among authors: shimada i. Nat Chem Biol. 2020 Apr;16(4):430-439. doi: 10.1038/s41589-019-0457-5. Epub 2020 Jan 20. Nat Chem Biol. 2020. PMID: 31959965

4

In situ structural biology using in-cell NMR.

Nishida N, Ito Y, Shimada I. Nishida N, et al. Among authors: shimada i. Biochim Biophys Acta Gen Subj. 2020 Feb;1864(2):129364. doi: 10.1016/j.bbagen.2019.05.007. Epub 2019 May 16. Biochim Biophys Acta Gen Subj. 2020. PMID: 31103749 Review.

5

Function-related conformational dynamics of G protein-coupled receptors revealed by NMR.

Ueda T, Kofuku Y, Okude J, Imai S, Shiraishi Y, Shimada I. Ueda T, et al. Among authors: shimada i. Biophys Rev. 2019 Jun;11(3):409-418. doi: 10.1007/s12551-019-00539-w. Epub 2019 May 17. Biophys Rev. 2019. PMID: 31102199 Free PMC article. Review.

6

Structural basis for two-way communication between dynein and microtubules.

Nishida N, Komori Y, Takarada O, Watanabe A, Tamura S, Kubo S, Shimada I, Kikkawa M. Nishida N, et al. Among authors: shimada i. Nat Commun. 2020 Feb 25;11(1):1038. doi: 10.1038/s41467-020-14842-8. Nat Commun. 2020. PMID: 32098965 Free PMC article.

7

Conformational equilibrium defines the variable induction of the multidrug-binding transcriptional repressor QacR.

Takeuchi K, Imai M, Shimada I. Takeuchi K, et al. Among authors: shimada i. Proc Natl Acad Sci U S A. 2019 Oct 1;116(40):19963-19972. doi: 10.1073/pnas.1906129116. Epub 2019 Sep 16. Proc Natl Acad Sci U S A. 2019. PMID: 31527244 Free PMC article.

8

Activation of adenosine A_2A receptor by lipids from docosahexaenoic acid revealed by NMR.

Mizumura T, Kondo K, Kurita M, Kofuku Y, Natsume M, Imai S, Shiraishi Y, Ueda T, Shimada I. Mizumura T, et al. Among authors: shimada i. Sci Adv. 2020 Mar 18;6(12):eaay8544. doi: 10.1126/sciadv.aay8544. eCollection 2020 Mar. Sci Adv. 2020. PMID: 32206717 Free PMC article.

9

Real-Time In-Cell NMR Reveals the Intracellular Modulation of GTP-Bound Levels of RAS.

Zhao Q, Fujimiya R, Kubo S, Marshall CB, Ikura M, Shimada I, Nishida N. Zhao Q, et al. Among authors: shimada i. Cell Rep. 2020 Aug 25;32(8):108074. doi: 10.1016/j.celrep.2020.108074. Cell Rep. 2020. PMID: 32846131 Free article.

10

Conformational equilibrium shift underlies altered K⁺ channel gating as revealed by NMR.

Iwahashi Y, Toyama Y, Imai S, Itoh H, Osawa M, Inoue M, Shimada I. Iwahashi Y, et al. Among authors: shimada i. Nat Commun. 2020 Oct 14;11(1):5168. doi: 10.1038/s41467-020-19005-3. Nat Commun. 2020. PMID: 33057011 Free PMC article.

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