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141 results

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Page 1
Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021.
GBD 2021 Sickle Cell Disease Collaborators. GBD 2021 Sickle Cell Disease Collaborators. Lancet Haematol. 2023 Aug;10(8):e585-e599. doi: 10.1016/S2352-3026(23)00118-7. Epub 2023 Jun 15. Lancet Haematol. 2023. PMID: 37331373 Free PMC article.
We employed DisMod-MR 2.1 to triangulate between these measures-borrowing strength from predictive covariates and across age, time, and geography-and generated internally consistent estimates of incidence, prevalence, and mortality for three distinct genotypes of sickle
We employed DisMod-MR 2.1 to triangulate between these measures-borrowing strength from predictive covariates and across age, time, and geog …
Insight into the complex pathophysiology of sickle cell anaemia and possible treatment.
Piccin A, Murphy C, Eakins E, Rondinelli MB, Daves M, Vecchiato C, Wolf D, Mc Mahon C, Smith OP. Piccin A, et al. Eur J Haematol. 2019 Apr;102(4):319-330. doi: 10.1111/ejh.13212. Epub 2019 Feb 21. Eur J Haematol. 2019. PMID: 30664257 Review.
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the beta-globin gene. The resulting haemoglobin tetramer is poorly soluble when deoxygenated, and when this is prolonged, intracellular gelation of
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the beta
Preoperative blood transfusions for sickle cell disease.
Estcourt LJ, Kimber C, Trivella M, Doree C, Hopewell S. Estcourt LJ, et al. Cochrane Database Syst Rev. 2020 Jul 2;7(7):CD003149. doi: 10.1002/14651858.CD003149.pub4. Cochrane Database Syst Rev. 2020. PMID: 32614473 Free PMC article.
BACKGROUND: Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta globin) genes. ...The majority of surgical procedures were considered low or intermediate risk for …
BACKGROUND: Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inher …
Antiphospholipid Antibodies in Sickle Cell Disease: A Systematic Review and Exploratory Meta-Analysis.
Merashli M, Arcaro A, Graf M, Caruso M, Ames PRJ, Gentile F. Merashli M, et al. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211002914. doi: 10.1177/10760296211002914. Clin Appl Thromb Hemost. 2021. PMID: 33784835 Free PMC article.
The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically addressed. Our aim was to evaluate potential links between SCD and aPL in all age groups. ...
The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically …
Dynamics of neutrophil phenotype and function in sickle cell disease.
Gaartman AE, de Ligt LA, Beuger BM, Tool ATJ, Veldthuis M, Kuijpers TW, van Zwieten R, Biemond BJ, van Bruggen R, Nur E. Gaartman AE, et al. Front Immunol. 2025 May 2;16:1591283. doi: 10.3389/fimmu.2025.1591283. eCollection 2025. Front Immunol. 2025. PMID: 40386776 Free PMC article.
INTRODUCTION: While sickle cell disease (SCD) is primarily acknowledged as an erythrocyte disorder, emerging evidence suggests a role for altered neutrophil phenotype and function in SCD pathophysiology and disease severity. ...
INTRODUCTION: While sickle cell disease (SCD) is primarily acknowledged as an erythrocyte disorder, emerging evidence s …
Is the treatment of inflammatory arthritis different in sickle cell disease?
Kimyon G, İlhan G. Kimyon G, et al. Turk J Med Sci. 2022 Jun;52(5):1721-1728. doi: 10.55730/1300-0144.5515. Epub 2022 Oct 19. Turk J Med Sci. 2022. PMID: 36422487 Free PMC article.
Excluding patients with musculoskeletal findings associated with sickle cell disease (SCD), patients with chronic or acute inflammatory arthritis were enrolled into study. ...The use of drugs such as steroids, methotrexate, or anti-TNF in sickle cel
Excluding patients with musculoskeletal findings associated with sickle cell disease (SCD), patients with chronic or ac …
Characterization of microvascular disease in pediatric sickle cell disease using nailfold capillaroscopy.
Bharara R, Browne R, Seydafkan S, Salciccioli L, Rehman M, Zhang Y, Tena M, Malhi P, Hanono M, Chen SX, Daich J, Lazar JM. Bharara R, et al. Microvasc Res. 2021 Jul;136:104150. doi: 10.1016/j.mvr.2021.104150. Epub 2021 Feb 26. Microvasc Res. 2021. PMID: 33647341
Sickle cell disease (SCD) is a disorder with repetitive vaso-occlusive crises resulting in microvascular obstruction and tissue ischemia that may lead to multi-organ ischemia and dysfunction. ...In our SCD cohort, capillary number was unrelated to our availab
Sickle cell disease (SCD) is a disorder with repetitive vaso-occlusive crises resulting in microvascular obstruction an
Regular long-term red blood cell transfusions for managing chronic chest complications in sickle cell disease.
Estcourt LJ, Hopewell S, Trivella M, Hambleton IR, Cho G. Estcourt LJ, et al. Cochrane Database Syst Rev. 2019 Oct 25;2019(10):CD008360. doi: 10.1002/14651858.CD008360.pub5. Cochrane Database Syst Rev. 2019. PMID: 31684693 Free PMC article.
BACKGROUND: Sickle cell disease is a genetic haemoglobin disorder, which can cause severe pain, significant end-organ damage, pulmonary complications, and premature death. Sickle cell disease is one of the most common severe monogenic dis …
BACKGROUND: Sickle cell disease is a genetic haemoglobin disorder, which can cause severe pain, significant end-organ d …
Concomitant sickle cell disease and systemic lupus erythematosus: A single-center case series.
Lapite A, Sánchez LM, Altaffer AL, Rae M, Ramirez AA, Muscal E, Yildirim-Toruner C, Tubman VN. Lapite A, et al. Pediatr Blood Cancer. 2024 Oct;71(10):e31194. doi: 10.1002/pbc.31194. Epub 2024 Jul 14. Pediatr Blood Cancer. 2024. PMID: 39004780
Sickle cell disease (SCD) and systemic lupus erythematosus (SLE) are two uncommon disorders each characterized by multisystemic manifestations. ...
Sickle cell disease (SCD) and systemic lupus erythematosus (SLE) are two uncommon disorders each characterized by multi
Haemoglobinopathies and the rheumatologist.
Hughes M, Akram Q, Rees DC, Jones AK. Hughes M, et al. Rheumatology (Oxford). 2016 Dec;55(12):2109-2118. doi: 10.1093/rheumatology/kew042. Epub 2016 Mar 27. Rheumatology (Oxford). 2016. PMID: 27018056 Review.
The haemoglobinopathies are a relatively common, heterogeneous group of inherited conditions that are the result of either a quantitative abnormality (e.g. thalassaemia) or structural [e.g. sickle cell anaemia (SCA)] of the globin part of the haemoglobin molecule. M …
The haemoglobinopathies are a relatively common, heterogeneous group of inherited conditions that are the result of either a quantitative ab …
141 results