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127 results

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Page 1
Global, regional, and national prevalence and mortality burden of sickle cell disease, 2000-2021: a systematic analysis from the Global Burden of Disease Study 2021.
GBD 2021 Sickle Cell Disease Collaborators. GBD 2021 Sickle Cell Disease Collaborators. Lancet Haematol. 2023 Aug;10(8):e585-e599. doi: 10.1016/S2352-3026(23)00118-7. Epub 2023 Jun 15. Lancet Haematol. 2023. PMID: 37331373 Free PMC article.
We employed DisMod-MR 2.1 to triangulate between these measures-borrowing strength from predictive covariates and across age, time, and geography-and generated internally consistent estimates of incidence, prevalence, and mortality for three distinct genotypes of sickle …
We employed DisMod-MR 2.1 to triangulate between these measures-borrowing strength from predictive covariates and across age, time, and geog …
Insight into the complex pathophysiology of sickle cell anaemia and possible treatment.
Piccin A, Murphy C, Eakins E, Rondinelli MB, Daves M, Vecchiato C, Wolf D, Mc Mahon C, Smith OP. Piccin A, et al. Eur J Haematol. 2019 Apr;102(4):319-330. doi: 10.1111/ejh.13212. Epub 2019 Feb 21. Eur J Haematol. 2019. PMID: 30664257 Review.
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the beta-globin gene. The resulting haemoglobin tetramer is poorly soluble when deoxygenated, and when this is prolonged, intracellular gelation of …
Sickle cell anaemia (SCA) is the consequence of abnormal haemoglobin production due to an inherited point mutation in the beta …
Updated clinical classification of pulmonary hypertension.
Simonneau G, Gatzoulis MA, Adatia I, Celermajer D, Denton C, Ghofrani A, Gomez Sanchez MA, Krishna Kumar R, Landzberg M, Machado RF, Olschewski H, Robbins IM, Souza R. Simonneau G, et al. J Am Coll Cardiol. 2013 Dec 24;62(25 Suppl):D34-41. doi: 10.1016/j.jacc.2013.10.029. J Am Coll Cardiol. 2013. PMID: 24355639 Free article. Review.
Pulmonary hypertension associated with chronic hemolytic anemia has been moved from Group 1 PAH to Group 5, unclear/multifactorial mechanism. In addition, it was decided to add specific items related to pediatric pulmonary hypertension in order to create a comprehensive, c …
Pulmonary hypertension associated with chronic hemolytic anemia has been moved from Group 1 PAH to Group 5, unclear/multifactorial me …
Preoperative blood transfusions for sickle cell disease.
Estcourt LJ, Kimber C, Trivella M, Doree C, Hopewell S. Estcourt LJ, et al. Cochrane Database Syst Rev. 2020 Jul 2;7(7):CD003149. doi: 10.1002/14651858.CD003149.pub4. Cochrane Database Syst Rev. 2020. PMID: 32614473 Free PMC article.
BACKGROUND: Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inheritance of two abnormal haemoglobin (beta globin) genes. ...The majority of surgical procedures were considered low or intermediate risk for …
BACKGROUND: Sickle cell disease (SCD) is one of the commonest severe monogenic disorders in the world, due to the inher …
Is the treatment of inflammatory arthritis different in sickle cell disease?
Kimyon G, İlhan G. Kimyon G, et al. Turk J Med Sci. 2022 Jun;52(5):1721-1728. doi: 10.55730/1300-0144.5515. Epub 2022 Oct 19. Turk J Med Sci. 2022. PMID: 36422487 Free PMC article.
Excluding patients with musculoskeletal findings associated with sickle cell disease (SCD), patients with chronic or acute inflammatory arthritis were enrolled into study. ...The use of drugs such as steroids, methotrexate, or anti-TNF in sickle cel …
Excluding patients with musculoskeletal findings associated with sickle cell disease (SCD), patients with chronic or ac …
Antiphospholipid Antibodies in Sickle Cell Disease: A Systematic Review and Exploratory Meta-Analysis.
Merashli M, Arcaro A, Graf M, Caruso M, Ames PRJ, Gentile F. Merashli M, et al. Clin Appl Thromb Hemost. 2021 Jan-Dec;27:10760296211002914. doi: 10.1177/10760296211002914. Clin Appl Thromb Hemost. 2021. PMID: 33784835 Free PMC article.
The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically addressed. Our aim was to evaluate potential links between SCD and aPL in all age groups. ...
The relationship between antiphospholipid antibodies (aPL) and sickle cell disease (SCD) has never been systematically …
Characterization of microvascular disease in pediatric sickle cell disease using nailfold capillaroscopy.
Bharara R, Browne R, Seydafkan S, Salciccioli L, Rehman M, Zhang Y, Tena M, Malhi P, Hanono M, Chen SX, Daich J, Lazar JM. Bharara R, et al. Microvasc Res. 2021 Jul;136:104150. doi: 10.1016/j.mvr.2021.104150. Epub 2021 Feb 26. Microvasc Res. 2021. PMID: 33647341
Sickle cell disease (SCD) is a disorder with repetitive vaso-occlusive crises resulting in microvascular obstruction and tissue ischemia that may lead to multi-organ ischemia and dysfunction. ...In our SCD cohort, capillary number was unrelated to our availab …
Sickle cell disease (SCD) is a disorder with repetitive vaso-occlusive crises resulting in microvascular obstruction an …
Sickle cell disease and COVID-19: Atypical presentations and favorable outcomes.
Azerad MA, Bayoudh F, Weber T, Minon JM, Ketelslegers O, Hoyoux M, Ren X, Kaye O, De Marneffe N, Fraipont V, Masset C, Bouillon AS, Jaspers A, Tebache M, D'Hoen G, Habibi A, Efira A, Thachil J, Deckmyn H, Beguin Y. Azerad MA, et al. EJHaem. 2020 Aug 4;1(1):338-341. doi: 10.1002/jha2.74. eCollection 2020 Jul. EJHaem. 2020. PMID: 32838401 Free PMC article. No abstract available.
Coexistence of Relapsing Polychondritis and Sickle Cell Disease in a Child.
Tetteh BO, Yebuah FB, Amissah-Arthur MB, Dey D. Tetteh BO, et al. Case Rep Rheumatol. 2021 Nov 24;2021:3600451. doi: 10.1155/2021/3600451. eCollection 2021. Case Rep Rheumatol. 2021. PMID: 34868694 Free PMC article.
The pathogenesis of RP is poorly understood but suggests an autoimmune mechanism with a link to sickle cell disease yet to be established. Treatment is empiric with steroids, anti-inflammatory, and disease-modifying antirheumatic drugs being the mainst …
The pathogenesis of RP is poorly understood but suggests an autoimmune mechanism with a link to sickle cell disease yet …
Haemoglobinopathies and the rheumatologist.
Hughes M, Akram Q, Rees DC, Jones AK. Hughes M, et al. Rheumatology (Oxford). 2016 Dec;55(12):2109-2118. doi: 10.1093/rheumatology/kew042. Epub 2016 Mar 27. Rheumatology (Oxford). 2016. PMID: 27018056 Review.
The haemoglobinopathies are a relatively common, heterogeneous group of inherited conditions that are the result of either a quantitative abnormality (e.g. thalassaemia) or structural [e.g. sickle cell anaemia (SCA)] of the globin part of the haemoglobin molecule. M …
The haemoglobinopathies are a relatively common, heterogeneous group of inherited conditions that are the result of either a quantitative ab …
127 results