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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1968 3
1969 2
1970 3
1971 8
1972 5
1973 14
1974 11
1975 17
1976 11
1977 22
1978 15
1979 16
1980 15
1981 13
1982 14
1983 12
1984 8
1985 17
1986 15
1987 16
1988 21
1989 19
1990 26
1991 18
1992 27
1993 22
1994 17
1995 13
1996 18
1997 29
1998 29
1999 33
2000 40
2001 44
2002 58
2003 67
2004 63
2005 103
2006 110
2007 141
2008 128
2009 154
2010 201
2011 214
2012 231
2013 261
2014 246
2015 255
2016 265
2017 301
2018 284
2019 250
2020 104
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3,601 results
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Page 1
Silymarin/Silybin and Chronic Liver Disease: A Marriage of Many Years.
Federico A, Dallio M, Loguercio C. Federico A, et al. Molecules. 2017 Jan 24;22(2):191. doi: 10.3390/molecules22020191. Molecules. 2017. PMID: 28125040 Free PMC article. Review.
Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biological effect. ...With respect to alcohol abuse, silymarin is able to increase cellular vitality and to reduce both lipid peroxidation
Silymarin is the extract of Silybum marianum, or milk thistle, and its major active compound is silybin, which has a remarkable biolo
Silymarin and Its Role in Chronic Diseases.
Neha, Jaggi AS, Singh N. Neha, et al. Adv Exp Med Biol. 2016;929:25-44. doi: 10.1007/978-3-319-41342-6_2. Adv Exp Med Biol. 2016. PMID: 27771919 Review.
Silymarin is the active constituent of Silybum marianum (milk thistle) which is a C-25 containing flavonolignan. Milk thistle has a lot of traditional values, being used as a vegetable, as salad, as bitter tonic, and as galactogogue in nursing mothers and in various ailmen
Silymarin is the active constituent of Silybum marianum (milk thistle) which is a C-25 containing flavonolignan. Milk thistle has a l
The silymarin composition… and why does it matter???
Chambers CS, Holečková V, Petrásková L, Biedermann D, Valentová K, Buchta M, Křen V. Chambers CS, et al. Food Res Int. 2017 Oct;100(Pt 3):339-353. doi: 10.1016/j.foodres.2017.07.017. Epub 2017 Jul 12. Food Res Int. 2017. PMID: 28964357 Review.
As silybin is the main component of silymarin, the literature mainly focuses on this compound, ignoring all other components. ...There are studies dealing with the analytical separation and quantification of silymarin components as well as studies focused on sily
As silybin is the main component of silymarin, the literature mainly focuses on this compound, ignoring all other components. ...Ther …
Antiviral Activities of Silymarin and Derivatives.
Liu CH, Jassey A, Hsu HY, Lin LT. Liu CH, et al. Molecules. 2019 Apr 19;24(8):1552. doi: 10.3390/molecules24081552. Molecules. 2019. PMID: 31010179 Free PMC article. Review.
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective functions. ...This review will describe some of the latest preclinical and clinical studies detailing the antiviral profiles of silymarin and
Silymarin flavonolignans are well-known agents that typically possess antioxidative, anti-inflammatory, and hepatoprotective function
Effect of silymarin on biochemical indicators in patients with liver disease: Systematic review with meta-analysis.
de Avelar CR, Pereira EM, de Farias Costa PR, de Jesus RP, de Oliveira LPM. de Avelar CR, et al. World J Gastroenterol. 2017 Jul 21;23(27):5004-5017. doi: 10.3748/wjg.v23.i27.5004. World J Gastroenterol. 2017. PMID: 28785154 Free PMC article. Review.
AIM: To evaluate the effect of silymarin on the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and gamma glutamyl transpeptidase (γGT) in patients with liver diseases. ...The trials with adult and elderly patients of both sexes, with Liver …
AIM: To evaluate the effect of silymarin on the serum levels of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and …
Effects of silymarin on metabolic syndrome: a review.
Vahabzadeh M, Amiri N, Karimi G. Vahabzadeh M, et al. J Sci Food Agric. 2018 Oct;98(13):4816-4823. doi: 10.1002/jsfa.9115. Epub 2018 Jun 27. J Sci Food Agric. 2018. PMID: 29736939 Review.
There are emerging studies on preventive and therapeutic effects of silymarin on different components of metabolic syndrome. ...Reviewing different human and experimental studies into the effects of silymarin on metabolic syndrome, we deduced that silymarin p …
There are emerging studies on preventive and therapeutic effects of silymarin on different components of metabolic syndrome. ...Revie …
Silymarin in the prevention and treatment of liver diseases and primary liver cancer.
Féher J, Lengyel G. Féher J, et al. Curr Pharm Biotechnol. 2012 Jan;13(1):210-7. doi: 10.2174/138920112798868818. Curr Pharm Biotechnol. 2012. PMID: 21466434 Review.
In addition to this, anti-inflammatory activity and inhibitory effect of silymarin on the development of metastases have also been detected. In some neoplastic diseases silymarin can be administered as adjuvant therapy as well....
In addition to this, anti-inflammatory activity and inhibitory effect of silymarin on the development of metastases have also been de …
Formulation Strategies for Enhancing the Bioavailability of Silymarin: The State of the Art.
Di Costanzo A, Angelico R. Di Costanzo A, et al. Molecules. 2019 Jun 7;24(11):2155. doi: 10.3390/molecules24112155. Molecules. 2019. PMID: 31181687 Free PMC article. Review.
Equally promising are the effects of silymarin in protecting the brain from the inflammatory and oxidative stress effects by which metabolic syndrome contributes to neurodegenerative diseases. ...The purpose of this study is to review the different nanostructured systems a …
Equally promising are the effects of silymarin in protecting the brain from the inflammatory and oxidative stress effects by which me …
Silymarin: An interesting modality in dermatological therapeutics.
Dorjay K, Arif T, Adil M. Dorjay K, et al. Indian J Dermatol Venereol Leprol. 2018;84(2):238-243. doi: 10.4103/ijdvl.IJDVL_746_16. Indian J Dermatol Venereol Leprol. 2018. PMID: 29350205 Free article. Review. No abstract available.
Silymarin's Inhibition and Treatment Effects for Alzheimer's Disease.
Guo H, Cao H, Cui X, Zheng W, Wang S, Yu J, Chen Z. Guo H, et al. Molecules. 2019 May 6;24(9):1748. doi: 10.3390/molecules24091748. Molecules. 2019. PMID: 31064071 Free PMC article. Review.
Silymarin has always been valued by researchers for its good efficacy and safety in treating liver disease. Recent studies have shown that silymarin also has good pharmacological activity in the nervous system, especially for the treatment of AD. ...The good efficac
Silymarin has always been valued by researchers for its good efficacy and safety in treating liver disease. Recent studies have shown
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