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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1977 1
1979 1
1980 2
1981 2
1982 1
1983 2
1984 6
1985 3
1986 3
1987 4
1988 3
1989 1
1990 3
1991 7
1992 4
1993 3
1994 1
1995 3
1996 2
1997 1
1998 4
1999 7
2000 1
2001 2
2002 1
2003 3
2004 2
2005 1
2006 3
2007 5
2008 2
2009 6
2010 4
2011 9
2012 4
2013 7
2014 8
2015 8
2016 7
2017 13
2018 12
2019 15
2020 11
2021 12
2022 6
2023 8
2024 11
2025 8
2026 2

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206 results

Results by year

Filters applied: Meta-Analysis, Randomized Controlled Trial. Clear all
Page 1
The role of simeticone in small-bowel preparation for capsule endoscopy.
Ge ZZ, Chen HY, Gao YJ, Hu YB, Xiao SD. Ge ZZ, et al. Endoscopy. 2006 Aug;38(8):836-40. doi: 10.1055/s-2006-944634. Endoscopy. 2006. PMID: 17001575 Clinical Trial.
The patients were randomly allocated to groups receiving either simeticone or no simeticone, on the basis of a computer-generated random number table. Patients in the simeticone group (n = 28) received 300 mg simeticone for bowel preparation 20 min bef …
The patients were randomly allocated to groups receiving either simeticone or no simeticone, on the basis of a computer-genera …
Comparison of Two Forms of Loperamide-Simeticone and a Probiotic Yeast (Saccharomyces boulardii) in the Treatment of Acute Diarrhoea in Adults: A Randomised Non-Inferiority Clinical Trial.
Cottrell J, Koenig K, Perfekt R, Hofmann R; Loperamide–Simethicone Acute Diarrhoea Study Team. Cottrell J, et al. Drugs R D. 2015 Dec;15(4):363-73. doi: 10.1007/s40268-015-0111-y. Drugs R D. 2015. PMID: 26541878 Free PMC article. Clinical Trial.
The loperamide-simeticone groups had a shorter median TLUS [14.9 and 14.0 vs. 28.5 h (loperamide-simeticone caplet and chewable tablet groups, respectively, vs. ...S. boulardii), loperamide-simeticone chewable tablet 3.7 %, S. boulardii 5.7 %] and felt comple …
The loperamide-simeticone groups had a shorter median TLUS [14.9 and 14.0 vs. 28.5 h (loperamide-simeticone caplet and chewabl …
Clinical trial: the efficacy of alverine citrate/simeticone combination on abdominal pain/discomfort in irritable bowel syndrome--a randomized, double-blind, placebo-controlled study.
Wittmann T, Paradowski L, Ducrotté P, Bueno L, Andro Delestrain MC. Wittmann T, et al. Aliment Pharmacol Ther. 2010 Mar;31(6):615-24. doi: 10.1111/j.1365-2036.2009.04216.x. Epub 2009 Dec 10. Aliment Pharmacol Ther. 2010. PMID: 20003095 Clinical Trial.
BACKGROUND: Alverine citrate and simeticone combination has been used for almost 20 years in irritable bowel syndrome (IBS), but supportive scientific evidence of efficacy was limited. ...Patient receiving alverine citrate and simeticone reported greater global symp …
BACKGROUND: Alverine citrate and simeticone combination has been used for almost 20 years in irritable bowel syndrome (IBS), but supp …
On-demand treatment with alverine citrate/simeticone compared with standard treatments for irritable bowel syndrome: results of a randomised pragmatic study.
Ducrotte P, Grimaud JC, Dapoigny M, Personnic S, O'Mahony V, Andro-Delestrain MC. Ducrotte P, et al. Int J Clin Pract. 2014 Feb;68(2):245-54. doi: 10.1111/ijcp.12333. Epub 2013 Oct 21. Int J Clin Pract. 2014. PMID: 24147869 Free PMC article. Clinical Trial.
A randomised, double-blind, placebo-controlled study has shown the efficacy of alverine citrate/simeticone (ACS) combination for IBS symptom relief. AIM: As IBS symptoms are often intermittent, this pragmatic study was designed to compare the efficacy of an on-demand ACS t …
A randomised, double-blind, placebo-controlled study has shown the efficacy of alverine citrate/simeticone (ACS) combination for IBS …
Strategies to Improve Colonoscopy Preparation in Inflammatory Bowel Disease. A Systematic Review and Network Meta-analysis of Randomized Trials.
Chatterjee A, Kaur S, Jena A, Patil AN, Dutta U, Sebastian S, Sharma V. Chatterjee A, et al. J Gastrointestin Liver Dis. 2024 Jun 29;33(2):245-253. doi: 10.15403/jgld-5433. J Gastrointestin Liver Dis. 2024. PMID: 38944852 Free article.
On comparison with 4 liter (L) of poliethylen glycol (PEG), oral sulfate solution (OR=1.1, 95%CI: 0.65-1.86); PEG2L/Ascorbate (OR=0.98, 95%CI: 0.65-1.48); PEG1L (OR=1, 95%CI: 0.55-1.81); PEG2L plus bisacodyl (OR=1.08, 95%CI: 0.71-1.65); PEG4L plus simethicone (OR=1, 95%CI: …
On comparison with 4 liter (L) of poliethylen glycol (PEG), oral sulfate solution (OR=1.1, 95%CI: 0.65-1.86); PEG2L/Ascorbate (OR=0.98, 95%C …
Comparative efficacy of different bowel preparations for colonoscopy: A network meta-analysis.
Maida M, Marasco G, Fuccio L, Vitello A, Mocciaro F, Amata M, Fabbri A, Di Mitri R, Vassallo R, Ramai D, Hassan C, Repici A, Facciorusso A. Maida M, et al. Dig Liver Dis. 2025 Mar;57(3):688-696. doi: 10.1016/j.dld.2024.11.019. Epub 2024 Dec 15. Dig Liver Dis. 2025. PMID: 39676010
Overall, 2 L PEG + lactulose resulted as the best product (SUCRA 0.94), followed by 2 L PEG + simethicone (SUCRA 0.93). On network meta-analysis for ADR (17 RCTs, 6639 patients, 11 bowel preparations), only 2 L PEG + simethicone (RR = 1.60 [95 %CI = 1.05-2.43]) resu …
Overall, 2 L PEG + lactulose resulted as the best product (SUCRA 0.94), followed by 2 L PEG + simethicone (SUCRA 0.93). On network me …
Comparative Efficacy and Safety of 0.8-L Versus 2-L Polyethylene Glycol-Ascorbic Acid Solutions in Colonoscopy Preparation: A Prospective, Multicenter, Randomized, Controlled Trial.
Lee B, Keum B, Hong SN, Kim HG, Im JP, Na SY, Kwak MS, Nam K, Byeon JS. Lee B, et al. J Gastroenterol Hepatol. 2025 Sep;40(9):2248-2257. doi: 10.1111/jgh.70006. Epub 2025 Jul 24. J Gastroenterol Hepatol. 2025. PMID: 40704430 Free PMC article. Clinical Trial.
We compared a new 0.8-L PEG-ascorbic acid solution containing simethicone to a 2-L PEG-ascorbic acid solution. METHODS: In this prospective, investigator-blinded study, 137 outpatients from five centers were randomized into three groups: Group A (0.8-L PEG-ascorbic acid wi …
We compared a new 0.8-L PEG-ascorbic acid solution containing simethicone to a 2-L PEG-ascorbic acid solution. METHODS: In this prosp …
The effect of oral polyethylene glycol combined with simethicone for colonoscopy on cecal intubation rate, tolerability and acceptability : a systematic review and meta-analysis.
Li Y, Xing S, Chen R, Zhou Z, Guo Y. Li Y, et al. Acta Gastroenterol Belg. 2019 Jul-Sep;82(3):407-415. Acta Gastroenterol Belg. 2019. PMID: 31566329 Free article.
OBJECTIVE: To assess the efficacy adjunction of oral simethicone to polyethylene glycol as bowel preparation agent on cecal intubation rate. METHODS: We searched EMBASE, PubMed and Cochrane library for randomized controlled trials regarding simeticone plus polyethyl …
OBJECTIVE: To assess the efficacy adjunction of oral simethicone to polyethylene glycol as bowel preparation agent on cecal intubatio …
Exploring species-level infant gut bacterial biodiversity by meta-analysis and formulation of an optimized cultivation medium.
Alessandri G, Fontana F, Mancabelli L, Lugli GA, Tarracchini C, Argentini C, Longhi G, Viappiani A, Milani C, Turroni F, van Sinderen D, Ventura M. Alessandri G, et al. NPJ Biofilms Microbiomes. 2022 Oct 31;8(1):88. doi: 10.1038/s41522-022-00349-1. NPJ Biofilms Microbiomes. 2022. PMID: 36316342 Free PMC article.
Furthermore, this formulation was used to evaluate the in vitro effect of two drugs commonly used in pediatrics, i.e., acetaminophen and simethicone, on the taxonomic composition of the infant gut microbiota....
Furthermore, this formulation was used to evaluate the in vitro effect of two drugs commonly used in pediatrics, i.e., acetaminophen and …
Premedication in upper gastrointestinal endoscopy to improve mucosal visualization. A systematic review.
Linares-Ramírez JD, Córdoba AC, Calderón-Franco CH, Aponte-Martín DM, Dávila F, Sabbagh LC. Linares-Ramírez JD, et al. Rev Gastroenterol Peru. 2024 Oct-Dec;44(4):346-353. Rev Gastroenterol Peru. 2024. PMID: 39825811 English.
RESULTS: In patients undergoing an elective procedure, premedication with defoaming and/or mucolytic agents improved the visibility score of the gastric antrum during upper GI endoscopy. The use of combined agents such as simethicone vs. water and N-acetyl cysteine (NAC) v …
RESULTS: In patients undergoing an elective procedure, premedication with defoaming and/or mucolytic agents improved the visibility score of …
206 results