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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1925 1
1927 1
1947 1
1950 1
1951 1
1954 2
1956 1
1958 1
1959 2
1961 1
1962 1
1963 1
1964 1
1965 1
1966 3
1967 3
1968 8
1969 5
1970 11
1971 17
1972 32
1973 38
1974 46
1975 112
1976 116
1977 122
1978 124
1979 189
1980 193
1981 267
1982 324
1983 478
1984 598
1985 664
1986 822
1987 914
1988 1236
1989 1393
1990 1815
1991 2201
1992 2658
1993 3001
1994 3209
1995 3457
1996 3370
1997 3102
1998 3122
1999 3168
2000 3319
2001 3363
2002 3245
2003 3406
2004 3698
2005 3903
2006 3961
2007 4031
2008 4086
2009 4436
2010 4687
2011 5161
2012 5321
2013 5397
2014 5693
2015 5869
2016 5695
2017 5730
2018 5878
2019 6565
2020 7661
2021 9137
2022 9095
2023 1144
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77,930 results
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Comparative Analysis of Single-Cell RNA Sequencing Methods.
Ziegenhain C, Vieth B, Parekh S, Reinius B, Guillaumet-Adkins A, Smets M, Leonhardt H, Heyn H, Hellmann I, Enard W. Ziegenhain C, et al. Mol Cell. 2017 Feb 16;65(4):631-643.e4. doi: 10.1016/j.molcel.2017.01.023. Mol Cell. 2017. PMID: 28212749 Free article.
Single-cell RNA sequencing (scRNA-seq) offers new possibilities to address biological and medical questions. ...Power simulations at different sequencing depths showed that Drop-seq is more cost-efficient for transcriptome quantification of large numbe …
Single-cell RNA sequencing (scRNA-seq) offers new possibilities to address biological and medical questions. ...Power s …
Review of Single-Cell RNA Sequencing in the Heart.
Yamada S, Nomura S. Yamada S, et al. Int J Mol Sci. 2020 Nov 6;21(21):8345. doi: 10.3390/ijms21218345. Int J Mol Sci. 2020. PMID: 33172208 Free PMC article. Review.
Single-cell RNA sequencing (scRNA-seq) technology is a powerful, rapidly developing tool for characterizing individual cells and elucidating biological mechanisms at the cellular level. ...In this review, we summarize the various scRNA-seq platforms an …
Single-cell RNA sequencing (scRNA-seq) technology is a powerful, rapidly developing tool for characterizing individual …
Single-Cell RNA Sequencing in Hematological Diseases.
Zhu Y, Huang Y, Tan Y, Zhao W, Tian Q. Zhu Y, et al. Proteomics. 2020 Jul;20(13):e1900228. doi: 10.1002/pmic.201900228. Epub 2020 May 25. Proteomics. 2020. PMID: 32181578 Review.
Hematological diseases, including leukemia, lymphoma, and multiple myeloma, are characterized by high heterogeneity with diverse cellular subpopulations. Single-cell RNA sequencing (scRNA-seq), a transformational technology, provides deep insights into cel …
Hematological diseases, including leukemia, lymphoma, and multiple myeloma, are characterized by high heterogeneity with diverse cellular su …
Data Analysis in Single-Cell Transcriptome Sequencing.
Gao S. Gao S. Methods Mol Biol. 2018;1754:311-326. doi: 10.1007/978-1-4939-7717-8_18. Methods Mol Biol. 2018. PMID: 29536451
Single-cell transcriptome sequencing, often referred to as single-cell RNA sequencing (scRNA-seq), is used to measure gene expression at the single-cell level and provides a higher resolution of cellular differences than bul …
Single-cell transcriptome sequencing, often referred to as single-cell RNA sequencing (scRNA-seq), …
Fibroblast and Myofibroblast Subtypes: Single Cell Sequencing.
Soliman H, Tung LW, Rossi FMV. Soliman H, et al. Methods Mol Biol. 2021;2299:49-84. doi: 10.1007/978-1-0716-1382-5_4. Methods Mol Biol. 2021. PMID: 34028734
Studying populations at single cell resolution has enabled identification of new clusters of cells with unique transcriptional signatures. ...In this chapter, we first describe a procedure for purification and preparation of a single cell suspen …
Studying populations at single cell resolution has enabled identification of new clusters of cells with unique transcri …
Single-cell RNA sequencing identifies celltype-specific cis-eQTLs and co-expression QTLs.
van der Wijst MGP, Brugge H, de Vries DH, Deelen P, Swertz MA; LifeLines Cohort Study; BIOS Consortium; Franke L. van der Wijst MGP, et al. Nat Genet. 2018 Apr;50(4):493-497. doi: 10.1038/s41588-018-0089-9. Epub 2018 Apr 2. Nat Genet. 2018. PMID: 29610479 Free PMC article.
To identify these celltype-specific eQTLs using an unbiased approach, we used single-cell RNA sequencing to generate expression profiles of ~25,000 peripheral blood mononuclear cells from 45 donors. ...Finally, we generated personalized co-expression n …
To identify these celltype-specific eQTLs using an unbiased approach, we used single-cell RNA sequencing to generate ex …
Single-Cell Analyses Inform Mechanisms of Myeloid-Targeted Therapies in Colon Cancer.
Zhang L, Li Z, Skrzypczynska KM, Fang Q, Zhang W, O'Brien SA, He Y, Wang L, Zhang Q, Kim A, Gao R, Orf J, Wang T, Sawant D, Kang J, Bhatt D, Lu D, Li CM, Rapaport AS, Perez K, Ye Y, Wang S, Hu X, Ren X, Ouyang W, Shen Z, Egen JG, Zhang Z, Yu X. Zhang L, et al. Cell. 2020 Apr 16;181(2):442-459.e29. doi: 10.1016/j.cell.2020.03.048. Cell. 2020. PMID: 32302573 Free article.
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for defining cellular diversity in tumors, but its application toward dissecting mechanisms underlying immune-modulating therapies is scarce. ...Treatment with a CD40 agonist antibody preferentially ac …
Single-cell RNA sequencing (scRNA-seq) is a powerful tool for defining cellular diversity in tumors, but its applicatio …
Single-cell RNA sequencing: one step closer to the clinic.
Sklavenitis-Pistofidis R, Getz G, Ghobrial I. Sklavenitis-Pistofidis R, et al. Nat Med. 2021 Mar;27(3):375-376. doi: 10.1038/s41591-021-01276-y. Nat Med. 2021. PMID: 33664491 No abstract available.
MULTI-seq: sample multiplexing for single-cell RNA sequencing using lipid-tagged indices.
McGinnis CS, Patterson DM, Winkler J, Conrad DN, Hein MY, Srivastava V, Hu JL, Murrow LM, Weissman JS, Werb Z, Chow ED, Gartner ZJ. McGinnis CS, et al. Nat Methods. 2019 Jul;16(7):619-626. doi: 10.1038/s41592-019-0433-8. Epub 2019 Jun 17. Nat Methods. 2019. PMID: 31209384 Free PMC article.
We therefore developed MULTI-seq: multiplexing using lipid-tagged indices for single-cell and single-nucleus RNA sequencing. MULTI-seq reagents can barcode any cell type or nucleus from any species with an accessible plasma membrane. The method …
We therefore developed MULTI-seq: multiplexing using lipid-tagged indices for single-cell and single-nucleus RNA seq …
Single cell RNA sequencing of stem cell-derived retinal ganglion cells.
Daniszewski M, Senabouth A, Nguyen QH, Crombie DE, Lukowski SW, Kulkarni T, Sluch VM, Jabbari JS, Chamling X, Zack DJ, Pébay A, Powell JE, Hewitt AW. Daniszewski M, et al. Sci Data. 2018 Feb 13;5:180013. doi: 10.1038/sdata.2018.13. Sci Data. 2018. PMID: 29437159 Free PMC article.
We used single cell sequencing technology to characterize the transcriptomes of 1,174 human embryonic stem cell-derived retinal ganglion cells (RGCs) at the single cell level. ...Cells were harvested at day 36 and prepared f …
We used single cell sequencing technology to characterize the transcriptomes of 1,174 human embryonic stem cell- …
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