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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1944 1
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1948 1
1950 1
1953 1
1955 1
1957 1
1958 1
1959 4
1960 4
1961 15
1962 41
1963 76
1964 146
1965 428
1966 705
1967 1236
1968 1793
1969 2103
1970 1994
1971 2735
1972 3395
1973 3998
1974 4599
1975 3008
1976 1819
1977 1827
1978 1714
1979 1985
1980 2264
1981 2286
1982 2390
1983 2723
1984 3158
1985 3478
1986 3276
1987 3230
1988 3348
1989 3670
1990 3595
1991 3837
1992 3685
1993 3152
1994 3009
1995 2514
1996 2587
1997 2257
1998 2140
1999 2128
2000 2454
2001 2553
2002 2403
2003 2478
2004 2578
2005 2749
2006 2633
2007 2777
2008 2774
2009 2649
2010 2806
2011 2833
2012 2853
2013 2829
2014 2685
2015 2544
2016 2325
2017 2120
2018 2013
2019 2067
2020 2014
2021 1916
2022 1778
2023 1703
2024 1614
2025 1624
2026 802

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148,238 results

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Page 1
Size Exclusion Chromatography Strategies and MASH Explorer for Large Proteoform Characterization.
Tiambeng TN, Wu Z, Melby JA, Ge Y. Tiambeng TN, et al. Methods Mol Biol. 2022;2500:15-30. doi: 10.1007/978-1-0716-2325-1_3. Methods Mol Biol. 2022. PMID: 35657584 Free PMC article.
Top-down mass spectrometry (MS)-based analysis of larger proteoforms (>50 kDa) is typically challenging due to an exponential decay in the signal-to-noise ratio with increasing protein molecular weight (MW) and coelution with low-MW proteoforms. Size exclusion …
Top-down mass spectrometry (MS)-based analysis of larger proteoforms (>50 kDa) is typically challenging due to an exponential decay in th …
Fluorescence-Detection Size-Exclusion Chromatography-Based Thermostability Assay for Membrane Proteins.
Yao H, Cai H, Li D. Yao H, et al. Methods Mol Biol. 2023;2564:299-315. doi: 10.1007/978-1-0716-2667-2_16. Methods Mol Biol. 2023. PMID: 36107350
Of particular interest is the fluorescence-detector size-exclusion chromatography-based thermostability assay (FSEC-TS). By simple heating and FSEC, the generally applicable method allows rapid assessment of the thermostability of GFP-fused membrane proteins …
Of particular interest is the fluorescence-detector size-exclusion chromatography-based thermostability assay (FSEC-TS) …
Size exclusion chromatography as green support for forced degradation study of adalimumab.
Kovačić J, Klarić DA, Turk N, Mornar A. Kovačić J, et al. Acta Pharm. 2023 Dec 26;73(4):709-721. doi: 10.2478/acph-2023-0044. Print 2023 Dec 1. Acta Pharm. 2023. PMID: 38147477 Free article.
Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in their native form. ...
Size exclusion chromatography (SEC) has become a powerful tool for analysing size variants of biologic drugs in …
Size-exclusion chromatography for the characterization of urinary extracellular vesicles.
Park S, Jalaludin I, Hwang H, Ko M, Adelipour M, Hwan M, Cho N, Kim KK, Lubman DM, Kim J. Park S, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2023 Aug 1;1228:123828. doi: 10.1016/j.jchromb.2023.123828. Epub 2023 Jul 17. J Chromatogr B Analyt Technol Biomed Life Sci. 2023. PMID: 37480686 Free PMC article.
However, alternative enrichment methods such as size-exclusion chromatography (SEC) and polyethylene glycol-based precipitation have been introduced. ...Urinary EVs isolated from human urine using centrifugation (40,000 g) were analyzed using an SEC column …
However, alternative enrichment methods such as size-exclusion chromatography (SEC) and polyethylene glycol-based preci …
Direct coupling of size exclusion chromatography and mass spectrometry for the characterization of complex monoclonal antibody products.
Murisier A, Andrie M, Fekete S, Lauber M, D'Atri V, Iwan K, Guillarme D. Murisier A, et al. J Sep Sci. 2022 Jun;45(12):1997-2007. doi: 10.1002/jssc.202200075. Epub 2022 Mar 28. J Sep Sci. 2022. PMID: 35278285 Free PMC article.
The present study describes the possibilities offered by an innovative bioinert size exclusion chromatography column for size variant characterization of complex monoclonal antibody products. ...By using this innovative size exclusion …
The present study describes the possibilities offered by an innovative bioinert size exclusion chromatography column fo …
The Past, the Present, and the Future of the Size Exclusion Chromatography in Extracellular Vesicles Separation.
Kaddour H, Tranquille M, Okeoma CM. Kaddour H, et al. Viruses. 2021 Nov 13;13(11):2272. doi: 10.3390/v13112272. Viruses. 2021. PMID: 34835078 Free PMC article. Review.
Numerous techniques have been adapted for the separation of EVs with size exclusion chromatography (SEC)-based methods being the most promising. Here, we review the SEC protocols used for EV separation, and discuss opportunities for significant improvements, …
Numerous techniques have been adapted for the separation of EVs with size exclusion chromatography (SEC)-based methods …
Size-exclusion chromatography-based extracellular vesicle size subtyping and multiplex membrane protein profiling for differentiating gastrointestinal cancer prognosis.
Qin T, Li P, Li J, Guo Q, Chen Y, Wang YE, Tao L, Huang J, Shen X, Wu X. Qin T, et al. Analyst. 2023 Nov 6;148(22):5745-5752. doi: 10.1039/d3an01027a. Analyst. 2023. PMID: 37842723
However, the biomolecular and biophysical heterogeneity of EVs has restricted their application in clinical settings. In this article, we developed a size-exclusion chromatography-based technique for simultaneous EV size subtyping and protein profiling …
However, the biomolecular and biophysical heterogeneity of EVs has restricted their application in clinical settings. In this article, we de …
Microfluidic Size Exclusion Chromatography (muSEC) for Extracellular Vesicles and Plasma Protein Separation.
Leong SY, Ong HB, Tay HM, Kong F, Upadya M, Gong L, Dao M, Dalan R, Hou HW. Leong SY, et al. Small. 2022 Feb;18(6):e2104470. doi: 10.1002/smll.202104470. Epub 2022 Jan 5. Small. 2022. PMID: 34984816
Herein, a unique microfluidic platform is reported for EV-protein fractionation based on the principle of size exclusion chromatography (SEC). Using a novel rapid ( 20 min) replica molding technique, a fritless microfluidic SEC device (muSEC) is fabricated us …
Herein, a unique microfluidic platform is reported for EV-protein fractionation based on the principle of size exclusion ch …
The impact of storage on extracellular vesicles: A systematic study.
Gelibter S, Marostica G, Mandelli A, Siciliani S, Podini P, Finardi A, Furlan R. Gelibter S, et al. J Extracell Vesicles. 2022 Feb;11(2):e12162. doi: 10.1002/jev2.12162. J Extracell Vesicles. 2022. PMID: 35102719 Free PMC article.
EVs were collected from human plasma and murine microglia culture by size exclusion chromatography and ultracentrifugation, respectively. The analysis included: concentration, size and zeta potential (tunable resistive pulse sensing), contaminant prote …
EVs were collected from human plasma and murine microglia culture by size exclusion chromatography and ultracentrifugat …
Size-exclusion chromatography (SEC) of branched polymers and polysaccharides.
Gaborieau M, Castignolles P. Gaborieau M, et al. Anal Bioanal Chem. 2011 Feb;399(4):1413-23. doi: 10.1007/s00216-010-4221-7. Epub 2010 Oct 22. Anal Bioanal Chem. 2011. PMID: 20967430 Free PMC article. Review.
It also plays a key role in viscous properties, and thus in the mechanism of the separation of these polymers in size-exclusion chromatography (SEC). Critically reviewing the literature, particularly on SEC of polyolefins, polyacrylates and starch, we discuss …
It also plays a key role in viscous properties, and thus in the mechanism of the separation of these polymers in size-exclusion …
148,238 results
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