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Table representation of search results timeline featuring number of search results per year.

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151 results

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2 articles found by citation matching

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Page 1
The Skin Barrier and Moisturization: Function, Disruption, and Mechanisms of Repair.
Rajkumar J, Chandan N, Lio P, Shi V. Rajkumar J, et al. Skin Pharmacol Physiol. 2023;36(4):174-185. doi: 10.1159/000534136. Epub 2023 Sep 15. Skin Pharmacol Physiol. 2023. PMID: 37717558 Free article. Review.
BACKGROUND: The anatomic layers of the skin are well-defined, and a functional model of the skin barrier has recently been described. ...This review aimed to analyze the skin barrier in the context of the function model, with a foc …
BACKGROUND: The anatomic layers of the skin are well-defined, and a functional model of the skin barrier has rec …
Ceramide-Containing Adjunctive Skin Care for Skin Barrier Restoration During Acne Vulgaris Treatment.
Draelos ZD, Baalbaki N, Colon G, Dreno B. Draelos ZD, et al. J Drugs Dermatol. 2023 Jun 1;22(6):554-558. doi: 10.36849/JDD.7142. J Drugs Dermatol. 2023. PMID: 37276158 Clinical Trial.
Use of a ceramide-containing cleanser and moisturizer significantly reduced severity and incidence of dryness, erythema, and scaling while more quickly resolving barrier damage and restoring function. Draelos ZD, Baalbaki N, Colon G, et al. Ceramide
Use of a ceramide-containing cleanser and moisturizer significantly reduced severity and incidence of dryness, erythema, and s …
Stratum Corneum Lipids: Their Role for the Skin Barrier Function in Healthy Subjects and Atopic Dermatitis Patients.
van Smeden J, Bouwstra JA. van Smeden J, et al. Curr Probl Dermatol. 2016;49:8-26. doi: 10.1159/000441540. Epub 2016 Feb 4. Curr Probl Dermatol. 2016. PMID: 26844894 Review.
Human skin acts as a primary barrier between the body and its environment. Crucial for this skin barrier function is the lipid matrix in the outermost layer of the skin, the stratum corneum (SC). ...In addition, this review addresses how …
Human skin acts as a primary barrier between the body and its environment. Crucial for this skin barrier func
Role of topical emollients and moisturizers in the treatment of dry skin barrier disorders.
Lodén M. Lodén M. Am J Clin Dermatol. 2003;4(11):771-88. doi: 10.2165/00128071-200304110-00005. Am J Clin Dermatol. 2003. PMID: 14572299 Review.
Dryness is frequently linked to an impaired barrier function observed, for example, in atopic skin, psoriasis, ichthyosis, and contact dermatitis. ...Large differences also exist between moisturizing creams. Moisturizers have multiple functio
Dryness is frequently linked to an impaired barrier function observed, for example, in atopic skin, psoriasis, ichthyos …
Ceramides and Skin Health: New Insights.
Yong TL, Zaman R, Rehman N, Tan CK. Yong TL, et al. Exp Dermatol. 2025 Feb;34(2):e70042. doi: 10.1111/exd.70042. Exp Dermatol. 2025. PMID: 39912256 Review.
Creating a moisture barrier, preserving hydration, regulating pH, controlling inflammation, and enhancing skin functions and appearance are among its established benefits. It is often used medically to repair skin barrier defects, as obse …
Creating a moisture barrier, preserving hydration, regulating pH, controlling inflammation, and enhancing skin funct
Nicotinic acid/niacinamide and the skin.
Gehring W. Gehring W. J Cosmet Dermatol. 2004 Apr;3(2):88-93. doi: 10.1111/j.1473-2130.2004.00115.x. J Cosmet Dermatol. 2004. PMID: 17147561
Topical application of niacinamide has a stabilizing effect on epidermal barrier function, seen as a reduction in transepidermal water loss and an improvement in the moisture content of the horny layer. ...Because of its verifiable beneficial effects, niacina …
Topical application of niacinamide has a stabilizing effect on epidermal barrier function, seen as a reduction in transepiderm …
Noninvasive assessment of skin barrier function: evaluating ceramide-based moisturizer using confocal Raman spectroscopy.
Rajarahm P, Bi R, Attia AE, Zhang R, Thng STG, Ng SP, Yuan L, Olivo M. Rajarahm P, et al. J Biomed Opt. 2025 Dec;30(Suppl 3):S34117. doi: 10.1117/1.JBO.30.S3.S34117. Epub 2025 Dec 31. J Biomed Opt. 2025. PMID: 41503070 Free PMC article.
APPROACH: Skin physiological assessments and CRS measurements were performed to evaluate water content and ceramide levels in both superficial and deeper skin layers after application of the two moisturizers. ...CONCLUSIONS: These findings suggest that …
APPROACH: Skin physiological assessments and CRS measurements were performed to evaluate water content and ceramide levels in …
Topical supplementation with physiological lipids rebalances the stratum corneum ceramide profile and strengthens skin barrier function in adults predisposed to atopic dermatitis.
Andrew PV, Williams SF, Brown K, Chittock J, Pinnock A, Poyner A, Cork MJ, Danby SG. Andrew PV, et al. Br J Dermatol. 2025 Sep 18;193(4):729-740. doi: 10.1093/bjd/ljaf200. Br J Dermatol. 2025. PMID: 40408261 Free article. Clinical Trial.
BACKGROUND: People with atopic dermatitis (AD) suffer from dry, itchy skin with reduced skin barrier function that leaves it prone to irritant and allergen penetration. ...Our findings suggest that the addition of skin-identical lipids to moi
BACKGROUND: People with atopic dermatitis (AD) suffer from dry, itchy skin with reduced skin barrier function th …
Skin care interventions in infants for preventing eczema and food allergy.
Kelleher MM, Phillips R, Brown SJ, Cro S, Cornelius V, Carlsen KCL, Skjerven HO, Rehbinder EM, Lowe AJ, Dissanayake E, Shimojo N, Yonezawa K, Ohya Y, Yamamoto-Hanada K, Morita K, Axon E, Cork M, Cooke A, Van Vogt E, Schmitt J, Weidinger S, McClanahan D, Simpson E, Duley L, Askie LM, Williams HC, Boyle RJ. Kelleher MM, et al. Cochrane Database Syst Rev. 2022 Nov 14;11(11):CD013534. doi: 10.1002/14651858.CD013534.pub3. Cochrane Database Syst Rev. 2022. PMID: 36373988 Free PMC article.
They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an impaired skin barrier soon after birth is effective for preventing eczema or food allergy. ...SELECTION CRITERIA: We included R …
They can be associated with an impaired skin barrier in early infancy. It is unclear whether trying to prevent or reverse an i …
Skin condition and barrier function in individuals with a history of atopic dermatitis.
Cho E, Kim J, Kang B, Liu K, Cho C, Lee E, Ha J, Lim KM. Cho E, et al. Eur J Dermatol. 2025 Feb 1;35(1):16-24. doi: 10.1684/ejd.2025.4810. Eur J Dermatol. 2025. PMID: 40110816
However, the AD history group displayed significantly higher TEWL values, delayed skin barrier recovery following stratum corneum damage, and skin roughness on the inner forearm skin. Individuals with a history of AD, even after symptom resolution and …
However, the AD history group displayed significantly higher TEWL values, delayed skin barrier recovery following stratum corn …
151 results