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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1978 1
1981 2
1982 2
1983 2
1984 2
1985 2
1986 7
1987 6
1988 12
1989 17
1990 13
1991 24
1992 33
1993 36
1994 44
1995 35
1996 88
1997 76
1998 109
1999 111
2000 124
2001 140
2002 168
2003 181
2004 177
2005 209
2006 239
2007 224
2008 233
2009 244
2010 267
2011 236
2012 242
2013 244
2014 266
2015 231
2016 225
2017 226
2018 238
2019 212
2020 205
2021 200
2022 191
2023 176
2024 1

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5,190 results

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Page 1
Downregulation of KCNMA1 in mice accelerates auditory hair cells senescence via ferroptosis.
Tang X, Zhong H, Xu C, Sun Y, Lou Y, Zhao Y, Liang Y, Guo X, Pan C, Sun J, Sun J. Tang X, et al. Neurobiol Aging. 2023 Dec 2;134:115-125. doi: 10.1016/j.neurobiolaging.2023.10.011. Online ahead of print. Neurobiol Aging. 2023. PMID: 38056217
KCNMA1 encodes the K+ potassium channel alpha-subunit that plays a significant role in the auditory system. ...To verify the role of KCNMA1 in AHL, we downregulated KCNMA1 in HEI-OC1 cells by transfecting shRNA. ...
KCNMA1 encodes the K+ potassium channel alpha-subunit that plays a significant role in the auditory system. ...To verif …
Forced Abstinence from Volitional Ethanol Intake Drives a Vulnerable Period of Hyperexcitability in BNST-Projecting Insular Cortex Neurons.
Taylor A, Adank DN, Young PA, Quan Y, Nabit BP, Winder DG. Taylor A, et al. J Neurosci. 2023 Nov 22:JN-RM-1121-23. doi: 10.1523/JNEUROSCI.1121-23.2023. Online ahead of print. J Neurosci. 2023. PMID: 38050120
In contrast, in vivo ethanol exposure via i.p injection, ex vivo via ethanol wash and acute FA from a natural reward (sucrose) all failed to alter excitability. In situ hybridization studies revealed that at 24hrs post FA BK channel mRNA expression is reduced in IC. …
In contrast, in vivo ethanol exposure via i.p injection, ex vivo via ethanol wash and acute FA from a natural reward (sucrose) all failed to …
Structural mapping of patient-associated KCNMA1 gene variants.
Moldenhauer HJ, Tammen K, Meredith AL. Moldenhauer HJ, et al. Biophys J. 2023 Dec 1:S0006-3495(23)04120-6. doi: 10.1016/j.bpj.2023.11.3404. Online ahead of print. Biophys J. 2023. PMID: 38042986 Free article.
The disease mechanisms are predicted to result from alterations in KCNMA1-encoded BK K(+) channel activity; however, only a subset of the patient-associated variants have been functionally studied. ...These combined results reveal the distribution of potentia …
The disease mechanisms are predicted to result from alterations in KCNMA1-encoded BK K(+) channel activity; however, on …
Aerobic exercise improves BKCa channel-mediated vasodilation in diabetic vascular smooth muscle via AMPK/Nrf2/HO-1 pathway.
Liu Y, Cheng Y, Xiang N, Wang Z, Li S, Gong L, Wang X. Liu Y, et al. Acta Diabetol. 2023 Dec 2. doi: 10.1007/s00592-023-02210-z. Online ahead of print. Acta Diabetol. 2023. PMID: 38041787
AIMS: This study aims to investigate the effect of aerobic exercise training on BK(Ca) channel in diabetic vascular smooth muscle and explore the underlying mechanism. ...Aerobic exercise can promote the expression of BK(Ca) channel and improve BK …
AIMS: This study aims to investigate the effect of aerobic exercise training on BK(Ca) channel in diabetic vascular smooth mus …
Dual allosteric modulation of voltage and calcium sensitivities of the Slo1-LRRC channel complex.
Yamanouchi D, Kasuya G, Nakajo K, Kise Y, Nureki O. Yamanouchi D, et al. Mol Cell. 2023 Nov 23:S1097-2765(23)00921-8. doi: 10.1016/j.molcel.2023.11.005. Online ahead of print. Mol Cell. 2023. PMID: 38035882 Free article.
Modulation of large conductance intracellular ligand-activated potassium (BK) channel family (Slo1-3) by auxiliary subunits allows diverse physiological functions in excitable and non-excitable cells. ...However, the modulation mechanisms …
Modulation of large conductance intracellular ligand-activated potassium (BK) channel family (Slo1 …
The physiological basis with uterine myometrium contractions from electro-mechanical/hormonal myofibril function to the term and preterm labor.
Zangeneh FZ, Hantoushzadeh S. Zangeneh FZ, et al. Heliyon. 2023 Nov 19;9(11):e22259. doi: 10.1016/j.heliyon.2023.e22259. eCollection 2023 Nov. Heliyon. 2023. PMID: 38034762 Free PMC article. Review.
METHODS: We conducted a scoping narrative review using three online databases (PubMed, Scopus, and Science Direct). RESULTS: The review focused on ion channel functions in the myometrium, including sodium channels [Na K-ATPase, Na-activated K channels …
METHODS: We conducted a scoping narrative review using three online databases (PubMed, Scopus, and Science Direct). RESULTS: The review focu …
Long noncoding RNA KCNMA1-AS1 promotes osteogenic differentiation of human bone marrow mesenchymal stem cells by activating the SMAD9 signaling pathway.
Mai Z, Liu J, Jiang X, Gu W, Wang W, Li S, Schmalz G, Xiao H, Zhao J. Mai Z, et al. Biol Direct. 2023 Nov 29;18(1):81. doi: 10.1186/s13062-023-00425-2. Biol Direct. 2023. PMID: 38017487 Free PMC article.
However, precise roles and molecular mechanisms are still largely unknown. In this work, we report for the first time that lncRNA KCNMA1 antisense RNA 1 (KCNMA1-AS1) plays a vital role in regulating hBMSCs' osteogenic differentiation. ...In addition, KCNMA1-A …
However, precise roles and molecular mechanisms are still largely unknown. In this work, we report for the first time that lncRNA KCNMA1 …
Research on an Enhanced Detuned-Loading Effect in Integrated Two-Section DFB Lasers with High Modulation Bandwidths.
Zhang Y, Gu H, Ma G, Guan S, Fang T, Chen X. Zhang Y, et al. Micromachines (Basel). 2023 Oct 27;14(11):1994. doi: 10.3390/mi14111994. Micromachines (Basel). 2023. PMID: 38004851 Free PMC article.
The modulation bandwidth is increased from 17.5 GHz for a single DFB laser to around 24 GHz when the lasing wavelength is located on the left falling edge of the TS-DFB laser based on the detuned-loading effect, and it can be increased to 22 GHz for the right side. An eight-ch …
The modulation bandwidth is increased from 17.5 GHz for a single DFB laser to around 24 GHz when the lasing wavelength is located on the lef …
Ca2+-activated K+ channels modulate membrane potential in the human parathyroid cell: Possible role in exocytosis.
Bränström R, Vukojević V, Lu M, Shabo I, Mun HC, Conigrave AD, Farnebo LO, Larsson C. Bränström R, et al. Exp Cell Res. 2023 Nov 21;433(2):113858. doi: 10.1016/j.yexcr.2023.113858. Online ahead of print. Exp Cell Res. 2023. PMID: 37995920 Free article.
We showed that in single human parathyroid cells K(+) current is dependent on at least two types of Ca(2+)-activated K(+) channels: a small-conductance Ca(2+)-activated K(+) channel (K(SK)) and a large-conductance voltage and Ca(2+ …
We showed that in single human parathyroid cells K(+) current is dependent on at least two types of Ca(2+)-activated K(+) channels …
Acute, pro-contractile effects of prorenin on rat mesenteric arteries.
Rognant S, Baldwin SN, Pritchard HAT, Greenstein A, Calloe K, Aalkjaer C, Jepps TA. Rognant S, et al. FASEB J. 2023 Dec;37(12):e23282. doi: 10.1096/fj.202301480. FASEB J. 2023. PMID: 37994700
We found that the (P)RR is located within a distance of less than 40 nm from the V-ATPase, caveolin-1, ryanodine receptors, and large conductance Ca(2+) -activated K(+) channels (BK(Ca) ) in VSMCs. ...Inhibition of the V-ATPase with 100 nM bafil …
We found that the (P)RR is located within a distance of less than 40 nm from the V-ATPase, caveolin-1, ryanodine receptors, and large …
5,190 results