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Table representation of search results timeline featuring number of search results per year.

Year Number of Results
1974 1
1975 3
1977 3
1978 3
1979 3
1980 7
1981 7
1982 5
1983 1
1984 7
1985 6
1986 9
1987 8
1988 12
1989 5
1990 11
1991 14
1992 12
1993 13
1994 22
1995 7
1996 7
1997 8
1998 20
1999 20
2000 24
2001 13
2002 16
2003 14
2004 14
2005 17
2006 21
2007 14
2008 20
2009 27
2010 26
2011 27
2012 18
2013 20
2014 31
2015 25
2016 20
2017 22
2018 27
2019 23
2020 47
2021 35
2022 17
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690 results
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Page 1
Renin-Angiotensin System Pathway Therapeutics Associated With Improved Outcomes in Males Hospitalized With COVID-19.
Rocheleau GLY, Lee T, Mohammed Y, Goodlett D, Burns K, Cheng MP, Tran K, Sweet D, Marshall J, Slutsky AS, Murthy S, Singer J, Patrick DM, Du B, Peng Z, Lee TC, Boyd JH, Walley KR, Lamontagne F, Fowler R, Winston BW, Haljan G, Vinh DC, McGeer A, Maslove D, Patrigeon SP, Mann P, Donohoe K, Hernandez G, Russell JA; for ARBs CORONA I Investigators. Rocheleau GLY, et al. Among authors: slutsky as. Crit Care Med. 2022 May 19. doi: 10.1097/CCM.0000000000005589. Online ahead of print. Crit Care Med. 2022. PMID: 35607951
Omicron BA.1/1.1 SARS-CoV-2 Infection among Vaccinated Canadian Adults.
Brown PE, Fu SH, Bansal A, Newcombe L, Colwill K, Mailhot G, Delgado-Brand M, Gingras AC, Slutsky AS, Pasic M, Companion J, Bogoch II, Morawski E, Lam T, Reid A, Jha P; Ab-C Study Collaborators. Brown PE, et al. Among authors: slutsky as. N Engl J Med. 2022 May 18. doi: 10.1056/NEJMc2202879. Online ahead of print. N Engl J Med. 2022. PMID: 35584302 No abstract available.
The PANDORA Study: Prevalence and Outcome of Acute Hypoxemic Respiratory Failure in the Pre-COVID-19 Era.
Villar J, Mora-Ordoñez JM, Soler JA, Mosteiro F, Vidal A, Ambrós A, Fernández L, Murcia I, Civantos B, Romera MA, Mira A, Díaz-Domínguez FJ, Parrilla D, Martínez-Carmona JF, Martínez D, Pita-García L, Robaglia D, Bueno-González A, Sánchez-Ballesteros J, Pereyra ÁE, Hernández M, Chamorro-Jambrina C, Cobeta P, González-Luengo RI, Montiel R, Nogales L, Fernández MM, Arocas B, Valverde-Montoro Á, Del Saz-Ortiz AM, Olea-Jiménez V, Añón JM, Rodríguez-Suárez P, Fernández RL, Fernández C, Szakmany T, González-Martín JM, Ferrando C, Kacmarek RM, Slutsky AS. Villar J, et al. Among authors: slutsky as. Crit Care Explor. 2022 Apr 29;4(5):e0684. doi: 10.1097/CCE.0000000000000684. eCollection 2022 May. Crit Care Explor. 2022. PMID: 35510152 Free PMC article.
Physiology is Vital to Precision Medicine in ARDS and Sepsis.
Goligher EC, Telias I, Sahetya SK, Baedorf-Kassis E, Patel BK, Yehya N, Silversides JA, Ferguson ND, Brochard LJ, Lawler PR, Zarychanski R, Slutsky A. Goligher EC, et al. Among authors: slutsky a. Am J Respir Crit Care Med. 2022 Apr 20. doi: 10.1164/rccm.202202-0230ED. Online ahead of print. Am J Respir Crit Care Med. 2022. PMID: 35442864 No abstract available.
ECMO During Respiratory Pandemics: Past, Present, and Future.
Brodie D, Abrams D, MacLaren G, Brown CE, Evans L, Barbaro RP, Calfee CS, Hough CL, Fowles JA, Karagiannidis C, Slutsky AS, Combes A. Brodie D, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2022 Feb 25. doi: 10.1164/rccm.202111-2661CP. Online ahead of print. Am J Respir Crit Care Med. 2022. PMID: 35213298
Association of PEEP and Lung Recruitment Selection Strategies with Mortality in Acute Respiratory Distress Syndrome: A Systematic Review and Network Meta-Analysis.
Dianti J, Tisminetzky M, Ferreyro BL, Englesakis M, Del Sorbo L, Sud S, Talmor D, Ball L, Meade M, Hodgson C, Beitler JR, Sahetya S, Nichol A, Fan E, Rochwerg B, Brochard L, Slutsky AS, Ferguson ND, Serpa Neto A, Adhikari NK, Angriman F, Goligher EC. Dianti J, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2022 Feb 18. doi: 10.1164/rccm.202108-1972OC. Online ahead of print. Am J Respir Crit Care Med. 2022. PMID: 35180042
Assessment of SARS-CoV-2 Seropositivity During the First and Second Viral Waves in 2020 and 2021 Among Canadian Adults.
Tang X, Sharma A, Pasic M, Brown P, Colwill K, Gelband H, Birnboim HC, Nagelkerke N, Bogoch II, Bansal A, Newcombe L, Slater J, Rodriguez PS, Huang G, Fu SH, Meh C, Wu DC, Kaul R, Langlois MA, Morawski E, Hollander A, Eliopoulos D, Aloi B, Lam T, Abe KT, Rathod B, Fazel-Zarandi M, Wang J, Iskilova M, Pasculescu A, Caldwell L, Barrios-Rodiles M, Mohammed-Ali Z, Vas N, Santhanam DR, Cho ER, Qu K, Jha S, Jha V, Suraweera W, Malhotra V, Mastali K, Wen R, Sinha S, Reid A, Gingras AC, Chakraborty P, Slutsky AS, Jha P; Ab-C Study Investigators. Tang X, et al. Among authors: slutsky as. JAMA Netw Open. 2022 Feb 1;5(2):e2146798. doi: 10.1001/jamanetworkopen.2021.46798. JAMA Netw Open. 2022. PMID: 35171263 Free PMC article.
Effect of Moderate Hypothermia vs Normothermia on 30-Day Mortality in Patients With Cardiogenic Shock Receiving Venoarterial Extracorporeal Membrane Oxygenation: A Randomized Clinical Trial.
Levy B, Girerd N, Amour J, Besnier E, Nesseler N, Helms J, Delmas C, Sonneville R, Guidon C, Rozec B, David H, Bougon D, Chaouch O, Walid O, Hervé D, Belin N, Gaide-Chevronnay L, Rossignol P, Kimmoun A, Duarte K, Slutsky AS, Brodie D, Fellahi JL, Ouattara A, Combes A; HYPO-ECMO Trial Group and the International ECMO Network (ECMONet). Levy B, et al. Among authors: slutsky as. JAMA. 2022 Feb 1;327(5):442-453. doi: 10.1001/jama.2021.24776. JAMA. 2022. PMID: 35103766 Clinical Trial.
COVID-19 ARDS: getting ventilation right - Authors' reply.
Barbaro RP, MacLaren G, Swol J, Slutsky AS, Brodie D. Barbaro RP, et al. Among authors: slutsky as. Lancet. 2022 Jan 1;399(10319):22-23. doi: 10.1016/S0140-6736(21)02448-X. Lancet. 2022. PMID: 34973715 Free PMC article. No abstract available.
High-Flow Nasal Oxygen for Severe Hypoxemia: Oxygenation Response and Outcome in Patients with COVID-19.
Ranieri VM, Tonetti T, Navalesi P, Nava S, Antonelli M, Pesenti A, Grasselli G, Grieco DL, Menga LS, Pisani L, Boscolo A, Sella N, Pasin L, Mega C, Pizzilli G, Dell'Olio A, Dongilli R, Rucci P, Slutsky AS. Ranieri VM, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2022 Feb 15;205(4):431-439. doi: 10.1164/rccm.202109-2163OC. Am J Respir Crit Care Med. 2022. PMID: 34861135 Free PMC article.
Noninvasive respiratory support following extubation in critically ill adults: a systematic review and network meta-analysis.
Fernando SM, Tran A, Sadeghirad B, Burns KEA, Fan E, Brodie D, Munshi L, Goligher EC, Cook DJ, Fowler RA, Herridge MS, Cardinal P, Jaber S, Møller MH, Thille AW, Ferguson ND, Slutsky AS, Brochard LJ, Seely AJE, Rochwerg B. Fernando SM, et al. Among authors: slutsky as. Intensive Care Med. 2022 Feb;48(2):137-147. doi: 10.1007/s00134-021-06581-1. Epub 2021 Nov 25. Intensive Care Med. 2022. PMID: 34825256 Free article.
Acute Hypoxemic Respiratory Failure in Children at the Start of COVID-19 Outbreak: A Nationwide Experience.
López-Fernández YM, Martínez-de-Azagra A, González-Gómez JM, Pérez-Caballero Macarrón C, García-González M, Parrilla-Parrilla J, Miñambres-Rodríguez M, Madurga-Revilla P, Gómez-Zamora A, Rodríguez-Campoy P, Mayordomo-Colunga J, Butragueño-Laiseca L, Núñez-Borrero R, González-Martín JM, Slutsky AS, Villar J, On Behalf The Prevalence And Outcome Of Acute Hypoxemic Respiratory Failure In Children Pandora-Child Network. López-Fernández YM, et al. Among authors: slutsky as. J Clin Med. 2021 Sep 22;10(19):4301. doi: 10.3390/jcm10194301. J Clin Med. 2021. PMID: 34640318 Free PMC article.
Prognostic factors for development of acute respiratory distress syndrome following traumatic injury: a systematic review and meta-analysis.
Tran A, Fernando SM, Brochard LJ, Fan E, Inaba K, Ferguson ND, Calfee CS, Burns KEA, Brodie D, McCredie VA, Kim DY, Kyeremanteng K, Lampron J, Slutsky AS, Combes A, Rochwerg B. Tran A, et al. Among authors: slutsky as. Eur Respir J. 2022 Apr 14;59(4):2100857. doi: 10.1183/13993003.00857-2021. Print 2022 Apr. Eur Respir J. 2022. PMID: 34625477
Extracorporeal membrane oxygenation for COVID-19: evolving outcomes from the international Extracorporeal Life Support Organization Registry.
Barbaro RP, MacLaren G, Boonstra PS, Combes A, Agerstrand C, Annich G, Diaz R, Fan E, Hryniewicz K, Lorusso R, Paden ML, Stead CM, Swol J, Iwashyna TJ, Slutsky AS, Brodie D; Extracorporeal Life Support Organization. Barbaro RP, et al. Among authors: slutsky as. Lancet. 2021 Oct 2;398(10307):1230-1238. doi: 10.1016/S0140-6736(21)01960-7. Epub 2021 Sep 29. Lancet. 2021. PMID: 34599878 Free PMC article.
Synergistic Effect of Static Compliance and D-dimers to Predict Outcome of Patients with COVID-19-ARDS: A Prospective Multicenter Study.
Tonetti T, Grasselli G, Rucci P, Alessandri F, Dell'Olio A, Boscolo A, Pasin L, Sella N, Mega C, Melotti RM, Girardis M, Busani S, Bellani G, Foti G, Grieco DL, Scaravilli V, Protti A, Langer T, Mascia L, Pugliese F, Cecconi M, Fumagalli R, Nava S, Antonelli M, Slutsky AS, Navalesi P, Pesenti A, Ranieri VM. Tonetti T, et al. Among authors: slutsky as. Biomedicines. 2021 Sep 15;9(9):1228. doi: 10.3390/biomedicines9091228. Biomedicines. 2021. PMID: 34572414 Free PMC article.
Extracorporeal cardiopulmonary resuscitation in adults: evidence and implications.
Abrams D, MacLaren G, Lorusso R, Price S, Yannopoulos D, Vercaemst L, Bělohlávek J, Taccone FS, Aissaoui N, Shekar K, Garan AR, Uriel N, Tonna JE, Jung JS, Takeda K, Chen YS, Slutsky AS, Combes A, Brodie D. Abrams D, et al. Among authors: slutsky as. Intensive Care Med. 2022 Jan;48(1):1-15. doi: 10.1007/s00134-021-06514-y. Epub 2021 Sep 10. Intensive Care Med. 2022. PMID: 34505911 Free PMC article. Review.
Effect of Esophageal Pressure-guided Positive End-Expiratory Pressure on Survival from Acute Respiratory Distress Syndrome: A Risk-based and Mechanistic Reanalysis of the EPVent-2 Trial.
Sarge T, Baedorf-Kassis E, Banner-Goodspeed V, Novack V, Loring SH, Gong MN, Cook D, Talmor D, Beitler JR; EPVent-2 Study Group. Sarge T, et al. Am J Respir Crit Care Med. 2021 Nov 15;204(10):1153-1163. doi: 10.1164/rccm.202009-3539OC. Am J Respir Crit Care Med. 2021. PMID: 34464237 Clinical Trial.
Biotrauma during ultra-low tidal volume ventilation and venoarterial extracorporeal membrane oxygenation in cardiogenic shock: a randomized crossover clinical trial.
Amado-Rodríguez L, Del Busto C, López-Alonso I, Parra D, Mayordomo-Colunga J, Arias-Guillén M, Albillos-Almaraz R, Martín-Vicente P, López-Martínez C, Huidobro C, Camporota L, Slutsky AS, Albaiceta GM. Amado-Rodríguez L, et al. Among authors: slutsky as. Ann Intensive Care. 2021 Aug 28;11(1):132. doi: 10.1186/s13613-021-00919-0. Ann Intensive Care. 2021. PMID: 34453620 Free PMC article.
Therapeutic Anticoagulation with Heparin in Critically Ill Patients with Covid-19.
REMAP-CAP Investigators; ACTIV-4a Investigators; ATTACC Investigators, Goligher EC, Bradbury CA, McVerry BJ, Lawler PR, Berger JS, Gong MN, Carrier M, Reynolds HR, Kumar A, Turgeon AF, Kornblith LZ, Kahn SR, Marshall JC, Kim KS, Houston BL, Derde LPG, Cushman M, Tritschler T, Angus DC, Godoy LC, McQuilten Z, Kirwan BA, Farkouh ME, Brooks MM, Lewis RJ, Berry LR, Lorenzi E, Gordon AC, Ahuja T, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Contreras A, Costantini TW, de Brouwer S, Detry MA, Duggal A, Džavík V, Effron MB, Eng HF, Escobedo J, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, Fowler RA, Froess JD, Fu Z, Galanaud JP, Galen BT, Gandotra S, Girard TD, Goodman AL, Goossens H, Green C, Greenstein YY, Gross PL, Haniffa R, Hegde SM, Hendrickson CM, Higgins AM, Hindenburg AA, Hope AA, Horowitz JM, Horvat CM, Huang DT, Hudock K, Hunt BJ, Husain M, Hyzy RC, Jacobson JR, Jayakumar D, Keller NM, Khan A, Kim Y, Kindzelski A, King AJ, Knudson MM, Kornblith AE, Kutcher ME, Laffan MA, Lamontagne F, Le Gal G, Leeper CM, Leifer ES, Lim G, Gallego Lima F, Linstrum K, Litton E, Lopez-Sendon J, Lother SA, Marten N, Saud Marinez A, Martinez M, Mateos Garcia E, Mavromichalis S, McAuley DF, McDonald EG, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Mouncey PR, Murthy S, Nair GB, Nair R, Nichol AD, Nicolau JC, Nunez-Garcia B, Park JJ, Park PK, Parke RL, Parker JC, Parnia S, Paul JD, Pompilio M, Quigley JG, Rosenson RS, Rost NS, Rowan K, Santos FO, Santos M, Santos MO, Satterwhite L, Saunders CT, Schreiber J, Schutgens REG, Seymour CW, Siegal DM, Silva DG Jr, Singhal AB, Slutsky AS, Solvason D, Stanworth SJ, Turner AM, van Bentum-Puijk W, van de Veerdonk FL, van Diepen S, Vazquez-Grande G, Wahid L, Wareham V, Widmer RJ, Wilson JG, Yuriditsky E, Zhong Y, Berry SM, McArthur CJ, Neal MD, Hochman JS, Webb SA, Zarychanski R. REMAP-CAP Investigators, et al. Among authors: slutsky as. N Engl J Med. 2021 Aug 26;385(9):777-789. doi: 10.1056/NEJMoa2103417. Epub 2021 Aug 4. N Engl J Med. 2021. PMID: 34351722 Free PMC article. Clinical Trial.
Therapeutic Anticoagulation with Heparin in Noncritically Ill Patients with Covid-19.
ATTACC Investigators; ACTIV-4a Investigators; REMAP-CAP Investigators, Lawler PR, Goligher EC, Berger JS, Neal MD, McVerry BJ, Nicolau JC, Gong MN, Carrier M, Rosenson RS, Reynolds HR, Turgeon AF, Escobedo J, Huang DT, Bradbury CA, Houston BL, Kornblith LZ, Kumar A, Kahn SR, Cushman M, McQuilten Z, Slutsky AS, Kim KS, Gordon AC, Kirwan BA, Brooks MM, Higgins AM, Lewis RJ, Lorenzi E, Berry SM, Berry LR, Aday AW, Al-Beidh F, Annane D, Arabi YM, Aryal D, Baumann Kreuziger L, Beane A, Bhimani Z, Bihari S, Billett HH, Bond L, Bonten M, Brunkhorst F, Buxton M, Buzgau A, Castellucci LA, Chekuri S, Chen JT, Cheng AC, Chkhikvadze T, Coiffard B, Costantini TW, de Brouwer S, Derde LPG, Detry MA, Duggal A, Džavík V, Effron MB, Estcourt LJ, Everett BM, Fergusson DA, Fitzgerald M, Fowler RA, Galanaud JP, Galen BT, Gandotra S, García-Madrona S, Girard TD, Godoy LC, Goodman AL, Goossens H, Green C, Greenstein YY, Gross PL, Hamburg NM, Haniffa R, Hanna G, Hanna N, Hegde SM, Hendrickson CM, Hite RD, Hindenburg AA, Hope AA, Horowitz JM, Horvat CM, Hudock K, Hunt BJ, Husain M, Hyzy RC, Iyer VN, Jacobson JR, Jayakumar D, Keller NM, Khan A, Kim Y, Kindzelski AL, King AJ, Knudson MM, Kornblith AE, Krishnan V, Kutcher ME, Laffan MA, Lamontagne F, Le Gal G, Leeper CM, Leifer ES, Lim G, Lima FG, Linstrum K, Litton E, Lopez-Sendon J, Lopez-Sendon Moreno JL, Lother SA, Malhotra S, Marcos M, Saud Marinez A, Marshall JC, Marten N, Matthay MA, McAuley DF, McDonald EG, McGlothlin A, McGuinness SP, Middeldorp S, Montgomery SK, Moore SC, Morillo Guerrero R, Mouncey PR, Murthy S, Nair GB, Nair R, Nichol AD, Nunez-Garcia B, Pandey A, Park PK, Parke RL, Parker JC, Parnia S, Paul JD, Pérez González YS, Pompilio M, Prekker ME, Quigley JG, Rost NS, Rowan K, Santos FO, Santos M, Olombrada Santos M, Satterwhite L, Saunders CT, Schutgens REG, Seymour CW, Siegal DM, Silva DG Jr, Shankar-Hari M, Sheehan JP, Singhal AB, Solvason D, Stanworth SJ, Tritschler T, Turner AM, van Bentum-Puijk W, van de Veerdonk FL, van Diepen S, Vazquez-Grande G, Wahid L, Wareham V, Wells BJ, Widmer RJ, Wilson JG, Yuriditsky E, Zampieri FG, Angus DC, McArthur CJ, Webb SA, Farkouh ME, Hochman JS, Zarychanski R. ATTACC Investigators, et al. Among authors: slutsky as. N Engl J Med. 2021 Aug 26;385(9):790-802. doi: 10.1056/NEJMoa2105911. Epub 2021 Aug 4. N Engl J Med. 2021. PMID: 34351721 Free PMC article. Clinical Trial.
COVID-19-associated autoimmunity as a feature of acute respiratory failure.
Trahtemberg U, Fritzler MJ; On behalf of the COVID-19 chapter of the “Longitudinal Biomarkers in Lung Injury” study group. Trahtemberg U, et al. Intensive Care Med. 2021 Jul;47(7):801-804. doi: 10.1007/s00134-021-06408-z. Epub 2021 Apr 30. Intensive Care Med. 2021. PMID: 33928414 Free PMC article. No abstract available.
The novel Mechanical Ventilator Milano for the COVID-19 pandemic.
Abba A, Accorsi C, Agnes P, Alessi E, Amaudruz P, Annovi A, Desages FA, Back S, Badia C, Bagger J, Basile V, Batignani G, Bayo A, Bell B, Beschi M, Biagini D, Bianchi G, Bicelli S, Bishop D, Boccali T, Bombarda A, Bonfanti S, Bonivento WM, Bouchard M, Breviario M, Brice S, Brown R, Calvo-Mozota JM, Camozzi L, Camozzi M, Capra A, Caravati M, Carlini M, Ceccanti A, Celano B, Cela Ruiz JM, Charette C, Cogliati G, Constable M, Crippa C, Croci G, Cudmore S, Dahl CE, Dal Molin A, Daley M, Di Guardo C, D'Avenio G, Davignon O, Del Tutto M, De Ruiter J, Devoto A, Diaz Gomez Maqueo P, Di Francesco F, Dossi M, Druszkiewicz E, Duma C, Elliott E, Farina D, Fernandes C, Ferroni F, Finocchiaro G, Fiorillo G, Ford R, Foti G, Fournier RD, Franco D, Fricbergs C, Gabriele F, Galbiati C, Garcia Abia P, Gargantini A, Giacomelli L, Giacomini F, Giacomini F, Giarratana LS, Gillespie S, Giorgi D, Girma T, Gobui R, Goeldi D, Golf F, Gorel P, Gorini G, Gramellini E, Grosso G, Guescini F, Guetre E, Hackman G, Hadden T, Hawkins W, Hayashi K, Heavey A, Hersak G, Hessey N, Hockin G, Hudson K, Ianni A, Ienzi C, Ippolito V, James CC, Jillings C, Kendziora C, Khan S, Kim E, King M, King S, Kittmer A, Kochanek I, Kowalkowski J, Krücken R, Kushoro M, Kuula S, Laclaustra M, Leblond G, Lee L, Lennarz A, Leyton M, Li X, Liimatainen P, Lim C, Lindner T, Lomonaco T, Lu P, Lubna R, Lukhanin GA, Luzón G, MacDonald M, Magni G, Maharaj R, Manni S, Mapelli C, Margetak P, Martin L, Martin S, Martínez M, Massacret N, McClurg P, McDonald AB, Meazzi E, Migalla R, Mohayai T, Tosatti LM, Monzani G, Moretti C, Morrison B, Mountaniol M, Muraro A, Napoli P, Nati F, Natzke CR, Noble AJ, Norrick A, Olchanski K, Ortiz de Solorzano A, Padula F, Pallavicini M, Palumbo I, Panontin E, Papini N, Parmeggiano L, Parmeggiano S, Patel K, Patel A, Paterno M, Pellegrino C, Pelliccione P, Pesudo V, Pocar A, Pope A, Pordes S, Prelz F, Putignano O, Raaf JL, Ratti C, Razeti M, Razeto A, Reed D, Refsgaard J, Reilly T, Renshaw A, Retriere F, Riccobene E, Rigamonti D, Rizzi A, Rode J, Romualdez J, Russel L, Sablone D, Sala S, Salomoni D, Salvo P, Sandoval A, Sansoucy E, Santorelli R, Savarese C, Scapparone E, Schaubel T, Scorza S, Settimo M, Shaw B, Shawyer S, Sher A, Shi A, Skensved P, Slutsky A, Smith B, Smith NJT, Stenzler A, Straubel C, Stringari P, Suchenek M, Sur B, Tacchino S, Takeuchi L, Tardocchi M, Tartaglia R, Thomas E, Trask D, Tseng J, Tseng L, VanPagee L, Vedia V, Velghe B, Viel S, Visioli A, Viviani L, Vonica D, Wada M, Walter D, Wang H, Wang MHLS, Westerdale S, Wood D, Yates D, Yue S, Zambrano V. Abba A, et al. Among authors: slutsky a. Phys Fluids (1994). 2021 Mar;33(3):037122. doi: 10.1063/5.0044445. Epub 2021 Mar 23. Phys Fluids (1994). 2021. PMID: 33897243 Free PMC article.
Acute Cardiac Injury in Coronavirus Disease 2019 and Other Viral Infections-A Systematic Review and Meta-Analysis.
Cheng MP, Cau A, Lee TC, Brodie D, Slutsky A, Marshall J, Murthy S, Lee T, Singer J, Demir KK, Boyd J, Ohm H, Maslove D, Goffi A, Bogoch II, Sweet DD, Walley KR, Russell JA; Angiotensin Receptor Blocker Coronavirus Study (ARBs) CORONA I. Cheng MP, et al. Among authors: slutsky a. Crit Care Med. 2021 Sep 1;49(9):1558-1566. doi: 10.1097/CCM.0000000000005026. Crit Care Med. 2021. PMID: 33870918
Ventilator Weaning and Discontinuation Practices for Critically Ill Patients.
Burns KEA, Rizvi L, Cook DJ, Lebovic G, Dodek P, Villar J, Slutsky AS, Jones A, Kapadia FN, Gattas DJ, Epstein SK, Pelosi P, Kefala K, Meade MO; Canadian Critical Care Trials Group. Burns KEA, et al. Among authors: slutsky as. JAMA. 2021 Mar 23;325(12):1173-1184. doi: 10.1001/jama.2021.2384. JAMA. 2021. PMID: 33755077 Free PMC article.
Enabling a learning healthcare system with automated computer protocols that produce replicable and personalized clinician actions.
Morris AH, Stagg B, Lanspa M, Orme J, Clemmer TP, Weaver LK, Thomas F, Grissom CK, Hirshberg E, East TD, Wallace CJ, Young MP, Sittig DF, Pesenti A, Bombino M, Beck E, Sward KA, Weir C, Phansalkar SS, Bernard GR, Taylor Thompson B, Brower R, Truwit JD, Steingrub J, Duncan Hite R, Willson DF, Zimmerman JJ, Nadkarni VM, Randolph A, Curley MAQ, Newth CJL, Lacroix J, Agus MSD, Lee KH, deBoisblanc BP, Scott Evans R, Sorenson DK, Wong A, Boland MV, Grainger DW, Dere WH, Crandall AS, Facelli JC, Huff SM, Haug PJ, Pielmeier U, Rees SE, Karbing DS, Andreassen S, Fan E, Goldring RM, Berger KI, Oppenheimer BW, Wesley Ely E, Gajic O, Pickering B, Schoenfeld DA, Tocino I, Gonnering RS, Pronovost PJ, Savitz LA, Dreyfuss D, Slutsky AS, Crapo JD, Angus D, Pinsky MR, James B, Berwick D. Morris AH, et al. Among authors: slutsky as. J Am Med Inform Assoc. 2021 Jun 12;28(6):1330-1344. doi: 10.1093/jamia/ocaa294. J Am Med Inform Assoc. 2021. PMID: 33594410 Free PMC article.
A simple nomogram for predicting failure of non-invasive respiratory strategies in adults with COVID-19: a retrospective multicentre study.
Liu L, Xie J, Wu W, Chen H, Li S, He H, Yu Y, Hu M, Li J, Zheng R, Li X, Qiu H, Tong Z, Du B, Fan E, Yang Y, Slutsky AS. Liu L, et al. Among authors: slutsky as. Lancet Digit Health. 2021 Mar;3(3):e166-e174. doi: 10.1016/S2589-7500(20)30316-2. Epub 2021 Feb 8. Lancet Digit Health. 2021. PMID: 33573999 Free PMC article.
Media Portrayals of Outcomes After Extracorporeal Membrane Oxygenation.
Fernando SM, Mathew R, Slutsky AS, Rochwerg B, Kyeremanteng K, Combes A, Brodie D. Fernando SM, et al. Among authors: slutsky as. JAMA Intern Med. 2021 Mar 1;181(3):391-394. doi: 10.1001/jamainternmed.2020.6094. JAMA Intern Med. 2021. PMID: 33393994 Free PMC article.
Outcome of acute hypoxaemic respiratory failure: insights from the LUNG SAFE Study.
Pham T, Pesenti A, Bellani G, Rubenfeld G, Fan E, Bugedo G, Lorente JA, Fernandes ADV, Van Haren F, Bruhn A, Rios F, Esteban A, Gattinoni L, Larsson A, McAuley DF, Ranieri M, Thompson BT, Wrigge H, Brochard LJ, Laffey JG; LUNG SAFE Investigators and the European Society of Intensive Care Medicine Trials Group. Pham T, et al. Eur Respir J. 2021 Jun 10;57(6):2003317. doi: 10.1183/13993003.03317-2020. Print 2021 Jun. Eur Respir J. 2021. PMID: 33334944 Free article.
Gender-Based Differences in Outcomes Among Resuscitated Patients With Out-of-Hospital Cardiac Arrest.
Mody P, Pandey A, Slutsky AS, Segar MW, Kiss A, Dorian P, Parsons J, Scales DC, Rac VE, Cheskes S, Bierman AS, Abramson BL, Gray S, Fowler RA, Dainty KN, Idris AH, Morrison L. Mody P, et al. Among authors: slutsky as. Circulation. 2021 Feb 16;143(7):641-649. doi: 10.1161/CIRCULATIONAHA.120.050427. Epub 2020 Dec 15. Circulation. 2021. PMID: 33317326 Free PMC article.
Correction to: Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS.
Ferrando C, Suarez-Sipmann F, Mellado-Artigas R, Hernández M, Gea A, Arruti E, Aldecoa C, Martínez-Pallí G, Martínez-González MA, Slutsky AS, Villar J; COVID-19 Spanish ICU Network. Ferrando C, et al. Among authors: slutsky as. Intensive Care Med. 2021 Jan;47(1):144-146. doi: 10.1007/s00134-020-06251-8. Intensive Care Med. 2021. PMID: 33263817 Free PMC article. No abstract available.
Clinical trials in critical care: can a Bayesian approach enhance clinical and scientific decision making?
Yarnell CJ, Abrams D, Baldwin MR, Brodie D, Fan E, Ferguson ND, Hua M, Madahar P, McAuley DF, Munshi L, Perkins GD, Rubenfeld G, Slutsky AS, Wunsch H, Fowler RA, Tomlinson G, Beitler JR, Goligher EC. Yarnell CJ, et al. Among authors: slutsky as. Lancet Respir Med. 2021 Feb;9(2):207-216. doi: 10.1016/S2213-2600(20)30471-9. Epub 2020 Nov 20. Lancet Respir Med. 2021. PMID: 33227237 Free PMC article. Review.
The role for high flow nasal cannula as a respiratory support strategy in adults: a clinical practice guideline.
Rochwerg B, Einav S, Chaudhuri D, Mancebo J, Mauri T, Helviz Y, Goligher EC, Jaber S, Ricard JD, Rittayamai N, Roca O, Antonelli M, Maggiore SM, Demoule A, Hodgson CL, Mercat A, Wilcox ME, Granton D, Wang D, Azoulay E, Ouanes-Besbes L, Cinnella G, Rauseo M, Carvalho C, Dessap-Mekontso A, Fraser J, Frat JP, Gomersall C, Grasselli G, Hernandez G, Jog S, Pesenti A, Riviello ED, Slutsky AS, Stapleton RD, Talmor D, Thille AW, Brochard L, Burns KEA. Rochwerg B, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2226-2237. doi: 10.1007/s00134-020-06312-y. Epub 2020 Nov 17. Intensive Care Med. 2020. PMID: 33201321 Free PMC article.
Human soluble ACE2 improves the effect of remdesivir in SARS-CoV-2 infection.
Monteil V, Dyczynski M, Lauschke VM, Kwon H, Wirnsberger G, Youhanna S, Zhang H, Slutsky AS, Hurtado Del Pozo C, Horn M, Montserrat N, Penninger JM, Mirazimi A. Monteil V, et al. Among authors: slutsky as. EMBO Mol Med. 2021 Jan 11;13(1):e13426. doi: 10.15252/emmm.202013426. Epub 2020 Dec 14. EMBO Mol Med. 2021. PMID: 33179852 Free PMC article.
Current and evolving standards of care for patients with ARDS.
Menk M, Estenssoro E, Sahetya SK, Neto AS, Sinha P, Slutsky AS, Summers C, Yoshida T, Bein T, Ferguson ND. Menk M, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2157-2167. doi: 10.1007/s00134-020-06299-6. Epub 2020 Nov 6. Intensive Care Med. 2020. PMID: 33156382 Free PMC article. Review.
Extracorporeal life support for adults with acute respiratory distress syndrome.
Combes A, Schmidt M, Hodgson CL, Fan E, Ferguson ND, Fraser JF, Jaber S, Pesenti A, Ranieri M, Rowan K, Shekar K, Slutsky AS, Brodie D. Combes A, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2464-2476. doi: 10.1007/s00134-020-06290-1. Epub 2020 Nov 2. Intensive Care Med. 2020. PMID: 33140180 Free PMC article. Review.
Human recombinant soluble ACE2 in severe COVID-19.
Zoufaly A, Poglitsch M, Aberle JH, Hoepler W, Seitz T, Traugott M, Grieb A, Pawelka E, Laferl H, Wenisch C, Neuhold S, Haider D, Stiasny K, Bergthaler A, Puchhammer-Stoeckl E, Mirazimi A, Montserrat N, Zhang H, Slutsky AS, Penninger JM. Zoufaly A, et al. Among authors: slutsky as. Lancet Respir Med. 2020 Nov;8(11):1154-1158. doi: 10.1016/S2213-2600(20)30418-5. Epub 2020 Sep 24. Lancet Respir Med. 2020. PMID: 33131609 Free PMC article. No abstract available.
Evaluation of PEEP and prone positioning in early COVID-19 ARDS.
Mittermaier M, Pickerodt P, Kurth F, de Jarcy LB, Uhrig A, Garcia C, Machleidt F, Pergantis P, Weber S, Li Y, Breitbart A, Bremer F, Knape P, Dewey M, Doellinger F, Weber-Carstens S, Slutsky AS, Kuebler WM, Suttorp N, Müller-Redetzky H. Mittermaier M, et al. Among authors: slutsky as. EClinicalMedicine. 2020 Nov;28:100579. doi: 10.1016/j.eclinm.2020.100579. Epub 2020 Oct 11. EClinicalMedicine. 2020. PMID: 33073217 Free PMC article.
We've never seen a patient with ARDS!
Vincent JL, Slutsky AS. Vincent JL, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2133-2135. doi: 10.1007/s00134-020-06255-4. Epub 2020 Oct 13. Intensive Care Med. 2020. PMID: 33051737 Free PMC article. No abstract available.
What have we learned ventilating COVID-19 patients?
Trahtemberg U, Slutsky AS, Villar J. Trahtemberg U, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2458-2460. doi: 10.1007/s00134-020-06275-0. Epub 2020 Oct 12. Intensive Care Med. 2020. PMID: 33044572 Free PMC article. No abstract available.
Effect of Driving Pressure Change During Extracorporeal Membrane Oxygenation in Adults With Acute Respiratory Distress Syndrome: A Randomized Crossover Physiologic Study.
Del Sorbo L, Goffi A, Tomlinson G, Pettenuzzo T, Facchin F, Vendramin A, Goligher EC, Cypel M, Slutsky AS, Keshavjee S, Ferguson ND, Fan E; International ECMO Network (ECMONet). Del Sorbo L, et al. Among authors: slutsky as. Crit Care Med. 2020 Dec;48(12):1771-1778. doi: 10.1097/CCM.0000000000004637. Crit Care Med. 2020. PMID: 33044283 Clinical Trial.
Extracorporeal membrane oxygenation support in COVID-19: an international cohort study of the Extracorporeal Life Support Organization registry.
Barbaro RP, MacLaren G, Boonstra PS, Iwashyna TJ, Slutsky AS, Fan E, Bartlett RH, Tonna JE, Hyslop R, Fanning JJ, Rycus PT, Hyer SJ, Anders MM, Agerstrand CL, Hryniewicz K, Diaz R, Lorusso R, Combes A, Brodie D; Extracorporeal Life Support Organization. Barbaro RP, et al. Among authors: slutsky as. Lancet. 2020 Oct 10;396(10257):1071-1078. doi: 10.1016/S0140-6736(20)32008-0. Epub 2020 Sep 25. Lancet. 2020. PMID: 32987008 Free PMC article.
Association Between Administration of Systemic Corticosteroids and Mortality Among Critically Ill Patients With COVID-19: A Meta-analysis.
WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, Sterne JAC, Murthy S, Diaz JV, Slutsky AS, Villar J, Angus DC, Annane D, Azevedo LCP, Berwanger O, Cavalcanti AB, Dequin PF, Du B, Emberson J, Fisher D, Giraudeau B, Gordon AC, Granholm A, Green C, Haynes R, Heming N, Higgins JPT, Horby P, Jüni P, Landray MJ, Le Gouge A, Leclerc M, Lim WS, Machado FR, McArthur C, Meziani F, Møller MH, Perner A, Petersen MW, Savovic J, Tomazini B, Veiga VC, Webb S, Marshall JC. WHO Rapid Evidence Appraisal for COVID-19 Therapies (REACT) Working Group, et al. Among authors: slutsky as. JAMA. 2020 Oct 6;324(13):1330-1341. doi: 10.1001/jama.2020.17023. JAMA. 2020. PMID: 32876694 Free PMC article.
Pathophysiology of COVID-19-associated acute respiratory distress syndrome: a multicentre prospective observational study.
Grasselli G, Tonetti T, Protti A, Langer T, Girardis M, Bellani G, Laffey J, Carrafiello G, Carsana L, Rizzuto C, Zanella A, Scaravilli V, Pizzilli G, Grieco DL, Di Meglio L, de Pascale G, Lanza E, Monteduro F, Zompatori M, Filippini C, Locatelli F, Cecconi M, Fumagalli R, Nava S, Vincent JL, Antonelli M, Slutsky AS, Pesenti A, Ranieri VM; collaborators. Grasselli G, et al. Among authors: slutsky as. Lancet Respir Med. 2020 Dec;8(12):1201-1208. doi: 10.1016/S2213-2600(20)30370-2. Epub 2020 Aug 27. Lancet Respir Med. 2020. PMID: 32861276 Free PMC article.
Corticosteroid therapy for critically ill patients with COVID-19: A structured summary of a study protocol for a prospective meta-analysis of randomized trials.
Sterne JAC, Diaz J, Villar J, Murthy S, Slutsky AS, Perner A, Jüni P, Angus DC, Annane D, Azevedo LCP, Du B, Dequin PF, Gordon AC, Green C, Higgins JPT, Horby P, Landray MJ, Lapadula G, Le Gouge A, Leclerc M, Savović J, Tomazini B, Venkatesh B, Webb S, Marshall JC; WHO COVID-19 Clinical Management and Characterization Working Group. Sterne JAC, et al. Among authors: slutsky as. Trials. 2020 Aug 24;21(1):734. doi: 10.1186/s13063-020-04641-3. Trials. 2020. PMID: 32831155 Free PMC article.
Venoarterial extracorporeal membrane oxygenation to rescue sepsis-induced cardiogenic shock: a retrospective, multicentre, international cohort study.
Bréchot N, Hajage D, Kimmoun A, Demiselle J, Agerstrand C, Montero S, Schmidt M, Luyt CE, Lebreton G, Hékimian G, Flecher E, Zogheib E, Levy B, Slutsky AS, Brodie D, Asfar P, Combes A; International ECMO Network. Bréchot N, et al. Among authors: slutsky as. Lancet. 2020 Aug 22;396(10250):545-552. doi: 10.1016/S0140-6736(20)30733-9. Lancet. 2020. PMID: 32828186
Anti-Thrombotic Therapy to Ameliorate Complications of COVID-19 (ATTACC): Study design and methodology for an international, adaptive Bayesian randomized controlled trial.
Houston BL, Lawler PR, Goligher EC, Farkouh ME, Bradbury C, Carrier M, Dzavik V, Fergusson DA, Fowler RA, Galanaud JP, Gross PL, McDonald EG, Husain M, Kahn SR, Kumar A, Marshall J, Murthy S, Slutsky AS, Turgeon AF, Berry SM, Rosenson RS, Escobedo J, Nicolau JC, Bond L, Kirwan BA, de Brouwer S, Zarychanski R. Houston BL, et al. Among authors: slutsky as. Clin Trials. 2020 Oct;17(5):491-500. doi: 10.1177/1740774520943846. Epub 2020 Aug 20. Clin Trials. 2020. PMID: 32815416 Clinical Trial.
Efficacy of dexamethasone treatment for patients with the acute respiratory distress syndrome caused by COVID-19: study protocol for a randomized controlled superiority trial.
Villar J, Añón JM, Ferrando C, Aguilar G, Muñoz T, Ferreres J, Ambrós A, Aldecoa C, Suárez-Sipmann F, Thorpe KE, Jüni P, Slutsky AS; DEXA-COVID19 Network. Villar J, et al. Among authors: slutsky as. Trials. 2020 Aug 16;21(1):717. doi: 10.1186/s13063-020-04643-1. Trials. 2020. PMID: 32799933 Free PMC article.
Artificial intelligence in intensive care medicine.
Mamdani M, Slutsky AS. Mamdani M, et al. Among authors: slutsky as. Intensive Care Med. 2021 Feb;47(2):147-149. doi: 10.1007/s00134-020-06203-2. Epub 2020 Aug 7. Intensive Care Med. 2021. PMID: 32767073 No abstract available.
Clinical features, ventilatory management, and outcome of ARDS caused by COVID-19 are similar to other causes of ARDS.
Ferrando C, Suarez-Sipmann F, Mellado-Artigas R, Hernández M, Gea A, Arruti E, Aldecoa C, Martínez-Pallí G, Martínez-González MA, Slutsky AS, Villar J; COVID-19 Spanish ICU Network. Ferrando C, et al. Among authors: slutsky as. Intensive Care Med. 2020 Dec;46(12):2200-2211. doi: 10.1007/s00134-020-06192-2. Epub 2020 Jul 29. Intensive Care Med. 2020. PMID: 32728965 Free PMC article.
Temporary circulatory support for cardiogenic shock.
Combes A, Price S, Slutsky AS, Brodie D. Combes A, et al. Among authors: slutsky as. Lancet. 2020 Jul 18;396(10245):199-212. doi: 10.1016/S0140-6736(20)31047-3. Lancet. 2020. PMID: 32682486 Review.
Personalized Ventilation to Multiple Patients Using a Single Ventilator: Description and Proof of Concept.
Han JS, Mashari A, Singh D, Dianti J, Goligher E, Long M, Ng W, Wasowicz M, Preiss D, Vesely A, Kacmarek R, Keshavjee S, Brochard L, Fisher JA, Slutsky AS. Han JS, et al. Among authors: slutsky as. Crit Care Explor. 2020 May 6;2(5):e0118. doi: 10.1097/CCE.0000000000000118. eCollection 2020 May. Crit Care Explor. 2020. PMID: 32671348 Free PMC article.
The plasma peptides of sepsis.
Thavarajah T, Dos Santos CC, Slutsky AS, Marshall JC, Bowden P, Romaschin A, Marshall JG. Thavarajah T, et al. Among authors: slutsky as. Clin Proteomics. 2020 Jul 2;17:26. doi: 10.1186/s12014-020-09288-5. eCollection 2020. Clin Proteomics. 2020. PMID: 32636717 Free PMC article.
Influence of quality of intensive care on quality of life/return to work in survivors of the acute respiratory distress syndrome: prospective observational patient cohort study (DACAPO).
Apfelbacher C, Brandstetter S, Blecha S, Dodoo-Schittko F, Brandl M, Karagiannidis C, Quintel M, Kluge S, Putensen C, Bercker S, Ellger B, Kirschning T, Arndt C, Meybohm P, Weber-Carstens S; DACAPO study group, Bein T. Apfelbacher C, et al. BMC Public Health. 2020 Jun 5;20(1):861. doi: 10.1186/s12889-020-08943-8. BMC Public Health. 2020. PMID: 32503583 Free PMC article.
Inhibition of SARS-CoV-2 Infections in Engineered Human Tissues Using Clinical-Grade Soluble Human ACE2.
Monteil V, Kwon H, Prado P, Hagelkrüys A, Wimmer RA, Stahl M, Leopoldi A, Garreta E, Hurtado Del Pozo C, Prosper F, Romero JP, Wirnsberger G, Zhang H, Slutsky AS, Conder R, Montserrat N, Mirazimi A, Penninger JM. Monteil V, et al. Among authors: slutsky as. Cell. 2020 May 14;181(4):905-913.e7. doi: 10.1016/j.cell.2020.04.004. Epub 2020 Apr 24. Cell. 2020. PMID: 32333836 Free PMC article.
Coronavirus: just imagine….
Vincent JL, Slutsky AS. Vincent JL, et al. Among authors: slutsky as. Crit Care. 2020 Mar 16;24(1):90. doi: 10.1186/s13054-020-2824-8. Crit Care. 2020. PMID: 32178716 Free PMC article. No abstract available.
Association of Low Baseline Diaphragm Muscle Mass With Prolonged Mechanical Ventilation and Mortality Among Critically Ill Adults.
Sklar MC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, Rittayamai N, Harhay MO, Reid WD, Tomlinson G, Rozenberg D, McClelland W, Riegler S, Slutsky AS, Brochard L, Ferguson ND, Goligher EC. Sklar MC, et al. Among authors: slutsky as. JAMA Netw Open. 2020 Feb 5;3(2):e1921520. doi: 10.1001/jamanetworkopen.2019.21520. JAMA Netw Open. 2020. PMID: 32074293 Free article.
The plasma peptides of breast versus ovarian cancer.
Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG. Dufresne J, et al. Among authors: slutsky as. Clin Proteomics. 2019 Dec 23;16:43. doi: 10.1186/s12014-019-9262-0. eCollection 2019. Clin Proteomics. 2019. PMID: 31889940 Free PMC article.
A novel non-invasive method to detect excessively high respiratory effort and dynamic transpulmonary driving pressure during mechanical ventilation.
Bertoni M, Telias I, Urner M, Long M, Del Sorbo L, Fan E, Sinderby C, Beck J, Liu L, Qiu H, Wong J, Slutsky AS, Ferguson ND, Brochard LJ, Goligher EC. Bertoni M, et al. Among authors: slutsky as. Crit Care. 2019 Nov 6;23(1):346. doi: 10.1186/s13054-019-2617-0. Crit Care. 2019. PMID: 31694692 Free PMC article.
Prevention of viral transmission during lung transplantation with hepatitis C-viraemic donors: an open-label, single-centre, pilot trial.
Cypel M, Feld JJ, Galasso M, Pinto Ribeiro RV, Marks N, Kuczynski M, Kumar D, Bahinskaya I, Bagnato VS, Kurachi C, Slutsky AS, Yeung JC, Donahoe L, de Perrot M, Yasufuku K, Pierre A, Binnie M, Chaparro C, Martinu T, Chen M, Tikkanen J, Chow CW, Sidhu A, Waddell TK, Keshavjee S, Singer LG, Humar A. Cypel M, et al. Among authors: slutsky as. Lancet Respir Med. 2020 Feb;8(2):192-201. doi: 10.1016/S2213-2600(19)30268-1. Epub 2019 Oct 9. Lancet Respir Med. 2020. PMID: 31606437 Clinical Trial.
Variation in the practice of discontinuing mechanical ventilation in critically ill adults: study protocol for an international prospective observational study.
Burns KEA, Rizvi L, Cook DJ, Dodek P, Slutsky AS, Jones A, Villar J, Kapadia FN, Gattas DJ, Epstein SK, Meade MO; Canadian Critical Care Trials Group. Burns KEA, et al. Among authors: slutsky as. BMJ Open. 2019 Sep 8;9(9):e031775. doi: 10.1136/bmjopen-2019-031775. BMJ Open. 2019. PMID: 31501132 Free PMC article.
Determinants of the effect of extracorporeal carbon dioxide removal in the SUPERNOVA trial: implications for trial design.
Goligher EC, Combes A, Brodie D, Ferguson ND, Pesenti AM, Ranieri VM, Slutsky AS; SUPERNOVA investigators (European Society of Intensive Care Medicine trials group)  and for the International ECMO Network (ECMONet). Goligher EC, et al. Among authors: slutsky as. Intensive Care Med. 2019 Sep;45(9):1219-1230. doi: 10.1007/s00134-019-05708-9. Epub 2019 Aug 20. Intensive Care Med. 2019. PMID: 31432216
Practice Patterns and Ethical Considerations in the Management of Venovenous Extracorporeal Membrane Oxygenation Patients: An International Survey.
Abrams D, Pham T, Burns KEA, Combes A, Curtis JR, Mueller T, Prager KM, Serra A, Slutsky AS, Brodie D, Schmidt M; International ECMO Network (ECMONet). Abrams D, et al. Among authors: slutsky as. Crit Care Med. 2019 Oct;47(10):1346-1355. doi: 10.1097/CCM.0000000000003910. Crit Care Med. 2019. PMID: 31356471
Impact of Early Acute Kidney Injury on Management and Outcome in Patients With Acute Respiratory Distress Syndrome: A Secondary Analysis of a Multicenter Observational Study.
McNicholas BA, Rezoagli E, Pham T, Madotto F, Guiard E, Fanelli V, Bellani G, Griffin MD, Ranieri M, Laffey JG; ESICM Trials Group and the Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators. McNicholas BA, et al. Crit Care Med. 2019 Sep;47(9):1216-1225. doi: 10.1097/CCM.0000000000003832. Crit Care Med. 2019. PMID: 31162201
Early Paralytic Agents for ARDS? Yes, No, and Sometimes.
Slutsky AS, Villar J. Slutsky AS, et al. N Engl J Med. 2019 May 23;380(21):2061-2063. doi: 10.1056/NEJMe1905627. Epub 2019 May 19. N Engl J Med. 2019. PMID: 31112382 No abstract available.
Determinants of Depressive Symptoms at 1 Year Following ICU Discharge in Survivors of ≥ 7 Days of Mechanical Ventilation: Results From the RECOVER Program, a Secondary Analysis of a Prospective Multicenter Cohort Study.
Hamilton M, Tomlinson G, Chu L, Robles P, Matte A, Burns S, Thomas C, Lamontagne F, Adhikari NKJ, Ferguson N, Friedrich JO, Rudkowski JC, Skrobik Y, Meggison H, Cameron J, Herridge M; RECOVER Program Investigators; Canadian Critical Care Trials Group. Hamilton M, et al. Chest. 2019 Sep;156(3):466-476. doi: 10.1016/j.chest.2019.04.104. Epub 2019 May 15. Chest. 2019. PMID: 31102611
Post Hoc Bayesian Analyses-Reply.
Goligher EC, Tomlinson G, Slutsky AS. Goligher EC, et al. Among authors: slutsky as. JAMA. 2019 Apr 23;321(16):1632-1633. doi: 10.1001/jama.2019.1202. JAMA. 2019. PMID: 31012927 No abstract available.
ECMO for ARDS: from salvage to standard of care?
Abrams D, Ferguson ND, Brochard L, Fan E, Mercat A, Combes A, Pellegrino V, Schmidt M, Slutsky AS, Brodie D. Abrams D, et al. Among authors: slutsky as. Lancet Respir Med. 2019 Feb;7(2):108-110. doi: 10.1016/S2213-2600(18)30506-X. Epub 2019 Jan 11. Lancet Respir Med. 2019. PMID: 30642778 No abstract available.
The plasma peptides of ovarian cancer.
Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen CE, Diamandis EP, Michael Siu KW, Marshall JG. Dufresne J, et al. Among authors: slutsky as. Clin Proteomics. 2018 Dec 21;15:41. doi: 10.1186/s12014-018-9215-z. eCollection 2018. Clin Proteomics. 2018. PMID: 30598658 Free PMC article.
The plasma peptidome.
Dufresne J, Bowden P, Thavarajah T, Florentinus-Mefailoski A, Chen ZZ, Tucholska M, Norzin T, Ho MT, Phan M, Mohamed N, Ravandi A, Stanton E, Slutsky AS, Dos Santos CC, Romaschin A, Marshall JC, Addison C, Malone S, Heyland D, Scheltens P, Killestein J, Teunissen C, Diamandis EP, Siu KWM, Marshall JG. Dufresne J, et al. Among authors: slutsky as. Clin Proteomics. 2018 Dec 1;15:39. doi: 10.1186/s12014-018-9211-3. eCollection 2018. Clin Proteomics. 2018. PMID: 30519149 Free PMC article.
Outcomes of Patients Presenting with Mild Acute Respiratory Distress Syndrome: Insights from the LUNG SAFE Study.
Pham T, Serpa Neto A, Pelosi P, Laffey JG, De Haro C, Lorente JA, Bellani G, Fan E, Brochard LJ, Pesenti A, Schultz MJ, Artigas A; LUNG SAFE Investigators* and the European Society of Intensive Care Medicine Trials Group. Pham T, et al. Anesthesiology. 2019 Feb;130(2):263-283. doi: 10.1097/ALN.0000000000002508. Anesthesiology. 2019. PMID: 30499850 Free article.
Pulmonary phagocyte-derived NPY controls the pathology of severe influenza virus infection.
Fujiwara S, Hoshizaki M, Ichida Y, Lex D, Kuroda E, Ishii KJ, Magi S, Okada M, Takao H, Gandou M, Imai H, Hara R, Herzog H, Yoshimura A, Okamura H, Penninger JM, Slutsky AS, Uhlig S, Kuba K, Imai Y. Fujiwara S, et al. Among authors: slutsky as. Nat Microbiol. 2019 Feb;4(2):258-268. doi: 10.1038/s41564-018-0289-1. Epub 2018 Nov 19. Nat Microbiol. 2019. PMID: 30455472
Practice of diagnosis and management of acute respiratory distress syndrome in mainland China: a cross-sectional study.
Liu L, Yang Y, Gao Z, Li M, Mu X, Ma X, Li G, Sun W, Wang X, Gu Q, Zheng R, Zhao H, Ao D, Yu W, Wang Y, Chen K, Yan J, Li J, Cai G, Wang Y, Wang H, Kang Y, Slutsky AS, Liu S, Xie J, Qiu H. Liu L, et al. Among authors: slutsky as. J Thorac Dis. 2018 Sep;10(9):5394-5404. doi: 10.21037/jtd.2018.08.137. J Thorac Dis. 2018. PMID: 30416787 Free PMC article.
Spontaneous Breathing in Early Acute Respiratory Distress Syndrome: Insights From the Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE Study.
van Haren F, Pham T, Brochard L, Bellani G, Laffey J, Dres M, Fan E, Goligher EC, Heunks L, Lynch J, Wrigge H, McAuley D; Large observational study to UNderstand the Global impact of Severe Acute respiratory FailurE (LUNG SAFE) Investigators. van Haren F, et al. Crit Care Med. 2019 Feb;47(2):229-238. doi: 10.1097/CCM.0000000000003519. Crit Care Med. 2019. PMID: 30379668 Free PMC article.
ECMO for Severe Acute Respiratory Distress Syndrome.
Combes A, Slutsky AS, Brodie D. Combes A, et al. Among authors: slutsky as. N Engl J Med. 2018 Sep 13;379(11):1091-2. doi: 10.1056/NEJMc1808731. N Engl J Med. 2018. PMID: 30207913 No abstract available.
First tidal volume greater than 8 mL/kg is associated with increased mortality in complicated influenza infection with acute respiratory distress syndrome.
Chan MC, Chao WC, Liang SJ, Tseng CH, Wang HC, Chien YC, Yang KY, Chen WC, Perng WC, Kao KC, Hu HC, Sheu CC, Chang WA, Fang WF, Chen YM, Slutsky AS, Wu CL; for Taiwan Severe Influenza Research Consortium (TSIRC) Investigators. Chan MC, et al. Among authors: slutsky as. J Formos Med Assoc. 2019 Jan;118(1 Pt 2):378-385. doi: 10.1016/j.jfma.2018.06.010. Epub 2018 Jul 3. J Formos Med Assoc. 2019. PMID: 30041997 Free article.
Extracorporeal Membrane Oxygenation for Severe Acute Respiratory Distress Syndrome.
Combes A, Hajage D, Capellier G, Demoule A, Lavoué S, Guervilly C, Da Silva D, Zafrani L, Tirot P, Veber B, Maury E, Levy B, Cohen Y, Richard C, Kalfon P, Bouadma L, Mehdaoui H, Beduneau G, Lebreton G, Brochard L, Ferguson ND, Fan E, Slutsky AS, Brodie D, Mercat A; EOLIA Trial Group, REVA, and ECMONet. Combes A, et al. Among authors: slutsky as. N Engl J Med. 2018 May 24;378(21):1965-1975. doi: 10.1056/NEJMoa1800385. N Engl J Med. 2018. PMID: 29791822 Free article. Clinical Trial.
Evaluating Muscle Mass in Survivors of Acute Respiratory Distress Syndrome: A 1-Year Multicenter Longitudinal Study.
Chan KS, Mourtzakis M, Aronson Friedman L, Dinglas VD, Hough CL, Ely EW, Morris PE, Hopkins RO, Needham DM; National Institutes of Health National Heart, Lung, and Blood Institute (NHLBI) Acute Respiratory Distress Syndrome (ARDS) Network. Chan KS, et al. Crit Care Med. 2018 Aug;46(8):1238-1246. doi: 10.1097/CCM.0000000000003183. Crit Care Med. 2018. PMID: 29727365 Free PMC article.
Resolved versus confirmed ARDS after 24 h: insights from the LUNG SAFE study.
Madotto F, Pham T, Bellani G, Bos LD, Simonis FD, Fan E, Artigas A, Brochard L, Schultz MJ, Laffey JG; LUNG SAFE Investigators and the ESICM Trials Group. Madotto F, et al. Intensive Care Med. 2018 May;44(5):564-577. doi: 10.1007/s00134-018-5152-6. Epub 2018 Apr 9. Intensive Care Med. 2018. PMID: 29632996
Position paper for the organization of ECMO programs for cardiac failure in adults.
Abrams D, Garan AR, Abdelbary A, Bacchetta M, Bartlett RH, Beck J, Belohlavek J, Chen YS, Fan E, Ferguson ND, Fowles JA, Fraser J, Gong M, Hassan IF, Hodgson C, Hou X, Hryniewicz K, Ichiba S, Jakobleff WA, Lorusso R, MacLaren G, McGuinness S, Mueller T, Park PK, Peek G, Pellegrino V, Price S, Rosenzweig EB, Sakamoto T, Salazar L, Schmidt M, Slutsky AS, Spaulding C, Takayama H, Takeda K, Vuylsteke A, Combes A, Brodie D; International ECMO Network (ECMONet) and The Extracorporeal Life Support Organization (ELSO). Abrams D, et al. Among authors: slutsky as. Intensive Care Med. 2018 Jun;44(6):717-729. doi: 10.1007/s00134-018-5064-5. Epub 2018 Feb 15. Intensive Care Med. 2018. PMID: 29450594
Should basic science matter to clinicians?
Filewod NC, Batt J, Kapus A, Szaszi K, Fairn GD, Slutsky AS, Lee WL. Filewod NC, et al. Among authors: slutsky as. Lancet. 2018 Feb 3;391(10119):410-412. doi: 10.1016/S0140-6736(18)30199-5. Lancet. 2018. PMID: 29407017 No abstract available.
Research in Extracorporeal Life Support: A Call to Action.
Brodie D, Vincent JL, Brochard LJ, Combes A, Ferguson ND, Hodgson CL, Laffey JG, Mercat A, Pesenti A, Quintel M, Slutsky AS, Ranieri VM; International ECMO Network (ECMONet). Brodie D, et al. Among authors: slutsky as. Chest. 2018 Apr;153(4):788-791. doi: 10.1016/j.chest.2017.12.024. Epub 2018 Jan 31. Chest. 2018. PMID: 29355550 No abstract available.
Correction to: Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study.
Laffey JG, Bellani G, Pham T, Fan E, Madotto F, Bajwa EK, Brochard L, Clarkson K, Esteban A, Gattinoni L, van Haren F, Heunks LM, Kurahashi K, Laake JH, Larsson A, McAuley DF, McNamee L, Nin N, Qiu H, Ranieri M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Laffey JG, et al. Among authors: slutsky as. Intensive Care Med. 2018 Jan;44(1):157-165. doi: 10.1007/s00134-017-4981-z. Intensive Care Med. 2018. PMID: 29138899
Mechanical Ventilation-induced Diaphragm Atrophy Strongly Impacts Clinical Outcomes.
Goligher EC, Dres M, Fan E, Rubenfeld GD, Scales DC, Herridge MS, Vorona S, Sklar MC, Rittayamai N, Lanys A, Murray A, Brace D, Urrea C, Reid WD, Tomlinson G, Slutsky AS, Kavanagh BP, Brochard LJ, Ferguson ND. Goligher EC, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2018 Jan 15;197(2):204-213. doi: 10.1164/rccm.201703-0536OC. Am J Respir Crit Care Med. 2018. PMID: 28930478
Respiratory support in patients with acute respiratory distress syndrome: an expert opinion.
Chiumello D, Brochard L, Marini JJ, Slutsky AS, Mancebo J, Ranieri VM, Thompson BT, Papazian L, Schultz MJ, Amato M, Gattinoni L, Mercat A, Pesenti A, Talmor D, Vincent JL. Chiumello D, et al. Among authors: slutsky as. Crit Care. 2017 Sep 12;21(1):240. doi: 10.1186/s13054-017-1820-0. Crit Care. 2017. PMID: 28899408 Free PMC article. Review.
Mechanical Ventilation: State of the Art.
Pham T, Brochard LJ, Slutsky AS. Pham T, et al. Among authors: slutsky as. Mayo Clin Proc. 2017 Sep;92(9):1382-1400. doi: 10.1016/j.mayocp.2017.05.004. Mayo Clin Proc. 2017. PMID: 28870355 Review.
Treatment limitations in the era of ECMO.
Brodie D, Curtis JR, Vincent JL, Bakker J, Brown CE, Creteur J, Papazian L, Sladen RN, Ranieri VM; participants in the Round Table Conference. Brodie D, et al. Lancet Respir Med. 2017 Oct;5(10):769-770. doi: 10.1016/S2213-2600(17)30263-1. Epub 2017 Jul 10. Lancet Respir Med. 2017. PMID: 28705688 No abstract available.
Geo-economic variations in epidemiology, patterns of care, and outcomes in patients with acute respiratory distress syndrome: insights from the LUNG SAFE prospective cohort study.
Laffey JG, Madotto F, Bellani G, Pham T, Fan E, Brochard L, Amin P, Arabi Y, Bajwa EK, Bruhn A, Cerny V, Clarkson K, Heunks L, Kurahashi K, Laake JH, Lorente JA, McNamee L, Nin N, Palo JE, Piquilloud L, Qiu H, Jiménez JIS, Esteban A, McAuley DF, van Haren F, Ranieri M, Rubenfeld G, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Laffey JG, et al. Among authors: slutsky as. Lancet Respir Med. 2017 Aug;5(8):627-638. doi: 10.1016/S2213-2600(17)30213-8. Epub 2017 Jun 15. Lancet Respir Med. 2017. PMID: 28624388
Development of a zebrafish sepsis model for high-throughput drug discovery.
Philip AM, Wang Y, Mauro A, El-Rass S, Marshall JC, Lee WL, Slutsky AS, dosSantos CC, Wen XY. Philip AM, et al. Among authors: slutsky as. Mol Med. 2017 Jul;23:134-148. doi: 10.2119/molmed.2016.00188. Epub 2017 Jun 7. Mol Med. 2017. PMID: 28598490 Free PMC article.
An Official American Thoracic Society/European Society of Intensive Care Medicine/Society of Critical Care Medicine Clinical Practice Guideline: Mechanical Ventilation in Adult Patients with Acute Respiratory Distress Syndrome.
Fan E, Del Sorbo L, Goligher EC, Hodgson CL, Munshi L, Walkey AJ, Adhikari NKJ, Amato MBP, Branson R, Brower RG, Ferguson ND, Gajic O, Gattinoni L, Hess D, Mancebo J, Meade MO, McAuley DF, Pesenti A, Ranieri VM, Rubenfeld GD, Rubin E, Seckel M, Slutsky AS, Talmor D, Thompson BT, Wunsch H, Uleryk E, Brozek J, Brochard LJ; American Thoracic Society, European Society of Intensive Care Medicine, and Society of Critical Care Medicine. Fan E, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2017 May 1;195(9):1253-1263. doi: 10.1164/rccm.201703-0548ST. Am J Respir Crit Care Med. 2017. PMID: 28459336
Joblessness and Lost Earnings after Acute Respiratory Distress Syndrome in a 1-Year National Multicenter Study.
Kamdar BB, Huang M, Dinglas VD, Colantuoni E, von Wachter TM, Hopkins RO, Needham DM; National Heart, Lung, and Blood Institute Acute Respiratory Distress Syndrome Network. Kamdar BB, et al. Am J Respir Crit Care Med. 2017 Oct 15;196(8):1012-1020. doi: 10.1164/rccm.201611-2327OC. Am J Respir Crit Care Med. 2017. PMID: 28448162 Free PMC article.
Severity of Hypoxemia and Effect of High-Frequency Oscillatory Ventilation in Acute Respiratory Distress Syndrome.
Meade MO, Young D, Hanna S, Zhou Q, Bachman TE, Bollen C, Slutsky AS, Lamb SE, Adhikari NKJ, Mentzelopoulos SD, Cook DJ, Sud S, Brower RG, Thompson BT, Shah S, Stenzler A, Guyatt G, Ferguson ND. Meade MO, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2017 Sep 15;196(6):727-733. doi: 10.1164/rccm.201609-1938OC. Am J Respir Crit Care Med. 2017. PMID: 28245137
T regulatory cells and dendritic cells protect against transfusion-related acute lung injury via IL-10.
Kapur R, Kim M, Aslam R, McVey MJ, Tabuchi A, Luo A, Liu J, Li Y, Shanmugabhavananthan S, Speck ER, Zufferey A, Yousef G, Zhang H, Rondina MT, Weyrich AS, Porcelijn L, Kuebler WM, Slutsky AS, Semple JW. Kapur R, et al. Among authors: slutsky as. Blood. 2017 May 4;129(18):2557-2569. doi: 10.1182/blood-2016-12-758185. Epub 2017 Feb 15. Blood. 2017. PMID: 28202460 Free PMC article.
Potentially modifiable factors contributing to outcome from acute respiratory distress syndrome: the LUNG SAFE study.
Laffey JG, Bellani G, Pham T, Fan E, Madotto F, Bajwa EK, Brochard L, Clarkson K, Esteban A, Gattinoni L, van Haren F, Heunks LM, Kurahashi K, Laake JH, Larsson A, McAuley DF, McNamee L, Nin N, Qiu H, Ranieri M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators and the ESICM Trials Group. Laffey JG, et al. Among authors: slutsky as. Intensive Care Med. 2016 Dec;42(12):1865-1876. doi: 10.1007/s00134-016-4571-5. Epub 2016 Oct 18. Intensive Care Med. 2016. PMID: 27757516
Associations between ventilator settings during extracorporeal membrane oxygenation for refractory hypoxemia and outcome in patients with acute respiratory distress syndrome: a pooled individual patient data analysis : Mechanical ventilation during ECMO.
Serpa Neto A, Schmidt M, Azevedo LC, Bein T, Brochard L, Beutel G, Combes A, Costa EL, Hodgson C, Lindskov C, Lubnow M, Lueck C, Michaels AJ, Paiva JA, Park M, Pesenti A, Pham T, Quintel M, Marco Ranieri V, Ried M, Roncon-Albuquerque R Jr, Slutsky AS, Takeda S, Terragni PP, Vejen M, Weber-Carstens S, Welte T, Gama de Abreu M, Pelosi P, Schultz MJ; ReVA Research Network and the PROVE Network Investigators. Serpa Neto A, et al. Among authors: slutsky as. Intensive Care Med. 2016 Nov;42(11):1672-1684. doi: 10.1007/s00134-016-4507-0. Epub 2016 Sep 1. Intensive Care Med. 2016. PMID: 27586996 Free PMC article.
Noninvasive Ventilation of Patients with Acute Respiratory Distress Syndrome. Insights from the LUNG SAFE Study.
Bellani G, Laffey JG, Pham T, Madotto F, Fan E, Brochard L, Esteban A, Gattinoni L, Bumbasirevic V, Piquilloud L, van Haren F, Larsson A, McAuley DF, Bauer PR, Arabi YM, Ranieri M, Antonelli M, Rubenfeld GD, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Bellani G, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2017 Jan 1;195(1):67-77. doi: 10.1164/rccm.201606-1306OC. Am J Respir Crit Care Med. 2017. PMID: 27753501 Free article.
Intensive care medicine in 2050: the future of ICU treatments.
Vincent JL, Slutsky AS, Gattinoni L. Vincent JL, et al. Among authors: slutsky as. Intensive Care Med. 2017 Sep;43(9):1401-1402. doi: 10.1007/s00134-016-4556-4. Epub 2016 Oct 4. Intensive Care Med. 2017. PMID: 27704150 No abstract available.
Lung-Kidney Cross-Talk in the Critically Ill Patient.
Husain-Syed F, Slutsky AS, Ronco C. Husain-Syed F, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2016 Aug 15;194(4):402-14. doi: 10.1164/rccm.201602-0420CP. Am J Respir Crit Care Med. 2016. PMID: 27337068 Review.
One-Year Outcomes in Caregivers of Critically Ill Patients.
Cameron JI, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, dos Santos C, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hébert P, Slutsky AS, Marshall JC, Cook D, Herridge MS; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. Cameron JI, et al. Among authors: slutsky as. N Engl J Med. 2016 May 12;374(19):1831-41. doi: 10.1056/NEJMoa1511160. N Engl J Med. 2016. PMID: 27168433 Free article.
Amiodarone, Lidocaine, or Placebo in Out-of-Hospital Cardiac Arrest.
Kudenchuk PJ, Brown SP, Daya M, Rea T, Nichol G, Morrison LJ, Leroux B, Vaillancourt C, Wittwer L, Callaway CW, Christenson J, Egan D, Ornato JP, Weisfeldt ML, Stiell IG, Idris AH, Aufderheide TP, Dunford JV, Colella MR, Vilke GM, Brienza AM, Desvigne-Nickens P, Gray PC, Gray R, Seals N, Straight R, Dorian P; Resuscitation Outcomes Consortium Investigators. Kudenchuk PJ, et al. N Engl J Med. 2016 May 5;374(18):1711-22. doi: 10.1056/NEJMoa1514204. Epub 2016 Apr 4. N Engl J Med. 2016. PMID: 27043165 Free article. Clinical Trial.
The RECOVER Program: Disability Risk Groups and 1-Year Outcome after 7 or More Days of Mechanical Ventilation.
Herridge MS, Chu LM, Matte A, Tomlinson G, Chan L, Thomas C, Friedrich JO, Mehta S, Lamontagne F, Levasseur M, Ferguson ND, Adhikari NK, Rudkowski JC, Meggison H, Skrobik Y, Flannery J, Bayley M, Batt J, Santos CD, Abbey SE, Tan A, Lo V, Mathur S, Parotto M, Morris D, Flockhart L, Fan E, Lee CM, Wilcox ME, Ayas N, Choong K, Fowler R, Scales DC, Sinuff T, Cuthbertson BH, Rose L, Robles P, Burns S, Cypel M, Singer L, Chaparro C, Chow CW, Keshavjee S, Brochard L, Hebert P, Slutsky AS, Marshall JC, Cook D, Cameron JI; RECOVER Program Investigators (Phase 1: towards RECOVER); Canadian Critical Care Trials Group. Herridge MS, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2016 Oct 1;194(7):831-844. doi: 10.1164/rccm.201512-2343OC. Am J Respir Crit Care Med. 2016. PMID: 26974173
Happy 50th birthday ARDS!
Slutsky AS, Villar J, Pesenti A. Slutsky AS, et al. Intensive Care Med. 2016 May;42(5):637-639. doi: 10.1007/s00134-016-4284-9. Epub 2016 Mar 14. Intensive Care Med. 2016. PMID: 26972902 No abstract available.
Pediatric High-Frequency Oscillation. The End of the Road?
Adhikari NK, Slutsky AS. Adhikari NK, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2016 Mar 1;193(5):471-2. doi: 10.1164/rccm.201511-2169ED. Am J Respir Crit Care Med. 2016. PMID: 26930425 No abstract available.
Epidemiology, Patterns of Care, and Mortality for Patients With Acute Respiratory Distress Syndrome in Intensive Care Units in 50 Countries.
Bellani G, Laffey JG, Pham T, Fan E, Brochard L, Esteban A, Gattinoni L, van Haren F, Larsson A, McAuley DF, Ranieri M, Rubenfeld G, Thompson BT, Wrigge H, Slutsky AS, Pesenti A; LUNG SAFE Investigators; ESICM Trials Group. Bellani G, et al. Among authors: slutsky as. JAMA. 2016 Feb 23;315(8):788-800. doi: 10.1001/jama.2016.0291. JAMA. 2016. PMID: 26903337
Trial of Continuous or Interrupted Chest Compressions during CPR.
Nichol G, Leroux B, Wang H, Callaway CW, Sopko G, Weisfeldt M, Stiell I, Morrison LJ, Aufderheide TP, Cheskes S, Christenson J, Kudenchuk P, Vaillancourt C, Rea TD, Idris AH, Colella R, Isaacs M, Straight R, Stephens S, Richardson J, Condle J, Schmicker RH, Egan D, May S, Ornato JP; ROC Investigators. Nichol G, et al. N Engl J Med. 2015 Dec 3;373(23):2203-14. doi: 10.1056/NEJMoa1509139. Epub 2015 Nov 9. N Engl J Med. 2015. PMID: 26550795 Free article. Clinical Trial.
Driving pressure as a key ventilation variable.
Costa EL, Slutsky AS, Amato MB. Costa EL, et al. Among authors: slutsky as. N Engl J Med. 2015 May 21;372(21):2072. doi: 10.1056/NEJMc1503487. N Engl J Med. 2015. PMID: 25992757 No abstract available.
Mechanical Stress and the Induction of Lung Fibrosis via the Midkine Signaling Pathway.
Zhang R, Pan Y, Fanelli V, Wu S, Luo AA, Islam D, Han B, Mao P, Ghazarian M, Zeng W, Spieth PM, Wang D, Khang J, Mo H, Liu X, Uhlig S, Liu M, Laffey J, Slutsky AS, Li Y, Zhang H. Zhang R, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2015 Aug 1;192(3):315-23. doi: 10.1164/rccm.201412-2326OC. Am J Respir Crit Care Med. 2015. PMID: 25945397 Clinical Trial.
Response to Perner et al.: testing current practice is no mistake.
Vincent JL, Hall JB, Slutsky AS. Vincent JL, et al. Among authors: slutsky as. Intensive Care Med. 2015 May;41(5):961. doi: 10.1007/s00134-015-3775-4. Epub 2015 Apr 8. Intensive Care Med. 2015. PMID: 25851388 No abstract available.
Driving pressure and survival in the acute respiratory distress syndrome.
Amato MB, Meade MO, Slutsky AS, Brochard L, Costa EL, Schoenfeld DA, Stewart TE, Briel M, Talmor D, Mercat A, Richard JC, Carvalho CR, Brower RG. Amato MB, et al. Among authors: slutsky as. N Engl J Med. 2015 Feb 19;372(8):747-55. doi: 10.1056/NEJMsa1410639. N Engl J Med. 2015. PMID: 25693014 Free article.
Feasibility and safety of hydrotherapy in critically ill ventilated patients.
Felten-Barentsz KM, Haans AJ, Slutsky AS, Heunks LM, van der Hoeven JG. Felten-Barentsz KM, et al. Among authors: slutsky as. Am J Respir Crit Care Med. 2015 Feb 15;191(4):476-7. doi: 10.1164/rccm.201408-1559LE. Am J Respir Crit Care Med. 2015. PMID: 25679106 Clinical Trial. No abstract available.
Human alveolar epithelial type II cells in primary culture.
Mao P, Wu S, Li J, Fu W, He W, Liu X, Slutsky AS, Zhang H, Li Y. Mao P, et al. Among authors: slutsky as. Physiol Rep. 2015 Feb 12;3(2):e12288. doi: 10.14814/phy2.12288. Print 2015 Feb 1. Physiol Rep. 2015. PMID: 25677546 Free PMC article.
Year in review 2013: Critical Care--respirology.
Curley GF, Slutsky AS. Curley GF, et al. Among authors: slutsky as. Crit Care. 2014 Oct 15;18(5):577. doi: 10.1186/s13054-014-0577-y. Crit Care. 2014. PMID: 25673260 Free PMC article. Review.
Is nosocomial infection really the major cause of death in sepsis?
Goldenberg NM, Leligdowicz A, Slutsky AS, Friedrich JO, Lee WL. Goldenberg NM, et al. Among authors: slutsky as. Crit Care. 2014 Oct 1;18(5):540. doi: 10.1186/s13054-014-0540-y. Crit Care. 2014. PMID: 25672933 Free PMC article. No abstract available.
Improving use of targeted temperature management after out-of-hospital cardiac arrest: a stepped wedge cluster randomized controlled trial.
Morrison LJ, Brooks SC, Dainty KN, Dorian P, Needham DM, Ferguson ND, Rubenfeld GD, Slutsky AS, Wax RS, Zwarenstein M, Thorpe K, Zhan C, Scales DC; Strategies for Post-Arrest Care Network. Morrison LJ, et al. Among authors: slutsky as. Crit Care Med. 2015 May;43(5):954-64. doi: 10.1097/CCM.0000000000000864. Crit Care Med. 2015. PMID: 25654175 Clinical Trial.
Chest compression rates and survival following out-of-hospital cardiac arrest.
Idris AH, Guffey D, Pepe PE, Brown SP, Brooks SC, Callaway CW, Christenson J, Davis DP, Daya MR, Gray R, Kudenchuk PJ, Larsen J, Lin S, Menegazzi JJ, Sheehan K, Sopko G, Stiell I, Nichol G, Aufderheide TP; Resuscitation Outcomes Consortium Investigators. Idris AH, et al. Crit Care Med. 2015 Apr;43(4):840-8. doi: 10.1097/CCM.0000000000000824. Crit Care Med. 2015. PMID: 25565457
Ten big mistakes in intensive care medicine.
Vincent JL, Hall JB, Slutsky AS. Vincent JL, et al. Among authors: slutsky as. Intensive Care Med. 2015 Mar;41(3):505-7. doi: 10.1007/s00134-014-3570-7. Epub 2014 Dec 11. Intensive Care Med. 2015. PMID: 25502093 No abstract available.
Bacteria and the neural code.
Steinberg BE, Tracey KJ, Slutsky AS. Steinberg BE, et al. Among authors: slutsky as. N Engl J Med. 2014 Nov 27;371(22):2131-3. doi: 10.1056/NEJMcibr1412003. N Engl J Med. 2014. PMID: 25427116 No abstract available.
Novel avian-origin influenza A (H7N9) in critically ill patients in China*.
Yang Y, Guo F, Zhao W, Gu Q, Huang M, Cao Q, Shi Y, Li J, Chen J, Yan J, Jin Z, Wang X, Deng Y, Sun L, Cai H, Huang J, Zheng Y, Li W, Liu A, Chen B, Zhou M, Qiu H, Slutsky AS. Yang Y, et al. Among authors: slutsky as. Crit Care Med. 2015 Feb;43(2):339-45. doi: 10.1097/CCM.0000000000000695. Crit Care Med. 2015. PMID: 25365721
Early activation of pro-fibrotic WNT5A in sepsis-induced acute lung injury.
Villar J, Cabrera-Benítez NE, Ramos-Nuez A, Flores C, García-Hernández S, Valladares F, López-Aguilar J, Blanch L, Slutsky AS. Villar J, et al. Among authors: slutsky as. Crit Care. 2014 Oct 21;18(5):568. doi: 10.1186/s13054-014-0568-z. Crit Care. 2014. PMID: 25331176 Free PMC article.
690 results